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Journal Articles

Randomized Phase 2 Open-Label Study of R-CHOP ± Bortezomib in Patients (Pts) with Untreated Non-Germinal Center B-Cell-like (Non-GCB) Subtype Diffuse Large Cell Lymphoma (DLBCL): Results from the Pyramid Trial (NCT00931918)

Blood (2015) 126 (23): 811.

https://doi.org/10.1182/blood.V126.23.811.811

Published: 2015

Journal Articles

Mutation of NRAS but not KRAS significantly reduces myeloma sensitivity to single-agent bortezomib therapy

Blood (2014) 123 (5): 632–639.

https://doi.org/10.1182/blood-2013-05-504340

Published: 2014

Includes: Supplemental data

Journal Articles

Suppression Of Uninvolved Immunoglobulin Has Significant Clinical Implication Including Predicting Relapse In Multiple Myeloma

Saulius Girnius, M.D., Rachel Neuwirth, Ph.D, Dixie-Lee Esseltine, MD, Kenneth C. Anderson, MD, Paul G. Richardson, MD, Munshi C Nikhil, MD

Blood (2013) 122 (21): 3151.

https://doi.org/10.1182/blood.V122.21.3151.3151

Published: 2013

Journal Articles

Efficacy and Safety Of Three Bortezomib-Based Induction and Maintenance Regimens In Previously Untreated, Transplant-Ineligible Multiple Myeloma (MM) Patients (Pts): Final Results From The Randomized, Phase 3b, US Community-Based UPFRONT Study (NCT00507416)

Ruben Niesvizky, MD, Ian Flinn, MD, PhD, Robert M. Rifkin, MD, James Essell, MD, Yousuf Gaffar, MD, Thomas Warr, MD, Rachel Neuwirth, Ph.D, Abbie Ba-Mancini, BS MBA, Yanyan Zhu, Ph.D, MPH, Liviu Niculescu, MD, James Reeves, MD

Blood (2013) 122 (21): 1966.

https://doi.org/10.1182/blood.V122.21.1966.1966

Published: 2013

Journal Articles

Risk of Second Primary Malignancies (SPMs) Following Bortezomib (Btz)-Based Therapy: Analysis of Four Phase 3 Randomized Controlled Trials in Previously Untreated or Relapsed Multiple Myeloma (MM)

Jesús F San Miguel, MD PhD, Paul G. Richardson, MD, Robert Z. Orlowski, MD, PhD, Hartmut Goldschmidt, Deyanira Corzo, MD, Carol Satler, Dixie-Lee Esseltine, MD, FRCPC, Rachel Neuwirth, MS, Maria Ponsillo, MD, Andrew Z Cakana, MD, FRCPath, Jay King, MD, William M Deraedt, PhD, Avinash Desai, Yana Lutska, Dina Gifkins, PhD, Kevin Liu, PhD, Pieter Sonneveld, MD, PhD

Blood (2011) 118 (21): 2933.

https://doi.org/10.1182/blood.V118.21.2933.2933

Published: 2011

Journal Articles

Patient-Reported Quality of Life (QoL) in Elderly, Newly Diagnosed Multiple Myeloma (MM) Patients Receiving Bortezomib-Based Combinations: Results From All Randomized Patients in the Community-Based, Phase 3b UPFRONT Study

Ruben Niesvizky, MD, Ian W. Flinn, MD, PhD, Robert Rifkin, MD, Nashat Gabrail, MD, Veena Charu, MD, Billy Clowney, MD, Yousuf Gaffar, MD, Thomas A. Warr, MD, FACP, Rachel Neuwirth, MS, Hui Huang, PhD, MBA, Sanggyu Choi, PhD, Deyanira Corzo, MD

Blood (2011) 118 (21): 1864.

https://doi.org/10.1182/blood.V118.21.1864.1864

Published: 2011

Journal Articles

Efficacy and Safety of Three Bortezomib-Based Combinations in Elderly, Newly Diagnosed Multiple Myeloma Patients: Results From All Randomized Patients in the Community-Based, Phase 3b UPFRONT Study

Ruben Niesvizky, MD, Ian W. Flinn, MD, PhD, Robert Rifkin, MD, Nashat Gabrail, MD, Veena Charu, MD, Billy Clowney, MD, James Essell, MD, Yousuf Gaffar, MD, Thomas A. Warr, MD, FACP, Rachel Neuwirth, MS, Deyanira Corzo, MD, James Reeves, MD

Blood (2011) 118 (21): 478.

https://doi.org/10.1182/blood.V118.21.478.478

Published: 2011

Journal Articles

Patient-Reported Quality of Life In Elderly, Newly Diagnosed Multiple Myeloma Patients Treated with Bortezomib-Based Regimens: Results From the Phase 3b UPFRONT Study

Ruben Niesvizky, MD, Ian W. Flinn, MD, PhD, Robert M. Rifkin, MD, Nashat Y Gabrail, MD, Veena Charu, MD, Billy Clowney, MD, James Essell, MD, Yousuf A Gaffar, MD, Thomas A. Warr, MD, Rachel Neuwirth, MS, Deyanira Corzo, MD, James A Reeves, MD

Blood (2010) 116 (21): 3026.

https://doi.org/10.1182/blood.V116.21.3026.3026

Published: 2010

Journal Articles

Herpes Zoster (HZ) Complicating Bortezomib Therapy of Relapsed/Refractory Indolent B-Cell and Mantle Cell Lymphoma: An Analysis of Two Phase II Trials.

Vicki A. Morrison, MD, Richard I Fisher, MD, Andre Goy, MD, Sven de Vos, Steven H. Bernstein, Anthony Boral, MD, PhD, Rachel Neuwirth, MS

Blood (2010) 116 (21): 2818.

https://doi.org/10.1182/blood.V116.21.2818.2818

Published: 2010

Journal Articles

Bortezomib In Combination with Rituximab, Cyclophosphamide, and Prednisone with or without Doxorubicin Followed by Rituximab Maintenance In Patients with Relapsed or Refractory Follicular Lymphoma: Results of a Phase 2 Study.

Michael Craig, MD, Wahid T Hanna, MD, Fernando Cabanillas, MD, Chien-Shing Chen, MD, PhD, Sudha Parasuraman, MD, Rachel Neuwirth, MS, Owen A. O'Connor, MD, PhD

Blood (2010) 116 (21): 2798.

https://doi.org/10.1182/blood.V116.21.2798.2798

Published: 2010

Journal Articles

Hematological Testing Is Not Required with Every Dose of Bortezomib In Patients with Adequate Blood Counts at the Start of Each Cycle

Pooja S. Raibagkar, MD, Paul G Richardson, Pieter Sonneveld, Michael W. Schuster, MD, David Irwin, MD, Edward A. Stadtmauer, MD, Thierry Facon, MD, Jean-Luc Harousseau, MD, Dina Ben-Yehuda, Sagar Lonial, MD, Hartmut Goldschmidt, Donna E. Reece, MD, Jesus F San Miguel, Joan Blade, Mario Boccadoro, Rachel Neuwirth, MS, Dixie-Lee Esseltine, MD, FRCPC, Kenneth C. Anderson, Nikhil C. Munshi, MD

Blood (2010) 116 (21): 1963.

https://doi.org/10.1182/blood.V116.21.1963.1963

Published: 2010

Journal Articles

Pharmacokinetics and Safety of Bortezomib In Patients with Advanced Malignancies and Varying Degrees of Liver Dysfunction: Results of the Phase 1 National Cancer Institute Organ Dysfunction Working Group Study NCI 6432

Karthik Venkatakrishnan, Ramesh K Ramanathan, John Sarantopoulos, Daniel L Mulkerin, Stephen I Shibata, Anne Hamilton, Afshin Dowlati, Sridhar Mani, Michelle A Rudek, Percy Ivy, Chris H Takimoto, Rachel Neuwirth, Sudha Parasuraman, Patricia M LoRusso

Blood (2010) 116 (21): 3975.

https://doi.org/10.1182/blood.V116.21.3975.3975

Published: 2010

Journal Articles

Phase 3b UPFRONT Study: Safety and Efficacy of Weekly Bortezomib Maintenance Therapy After Bortezomib-Based Induction Regimens In Elderly, Newly Diagnosed Multiple Myeloma Patients

Blood (2010) 116 (21): 619.

https://doi.org/10.1182/blood.V116.21.619.619

Published: 2010

Journal Articles

Phase 3b UPFRONT Study: Interim Results From a Community Practice-Based Prospective Randomized Trial Evaluating Three Bortezomib-Based Regimens in Elderly, Newly Diagnosed Multiple Myeloma Patients.

Ruben Niesvizky, James Reeves, Ian W Flinn, Robert M. Rifkin, Billy Clowney, Nashat Gabrail, Vijay R. Phooshkooru, Veena Charu, Christopher H. Chay, Deyanira Corzo, Rachel Neuwirth, Robert F. Manges, Thomas A. Warr

Blood (2009) 114 (22): 129.

https://doi.org/10.1182/blood.V114.22.129.129

Published: 2009

Journal Articles

Bortezomib Plus Melphalan and Prednisone as Induction Prior to Transplant or as Frontline Therapy for Non-Transplant Candidates in Patients with Previously Untreated Multiple Myeloma.

Cristina Gasparetto, MD, Jon P Gockerman, Louis F Diehl, MD, Carlos de Castro, III, MD, Joseph O Moore, Gwynn D Long, Mitchell Horwitz, MD, John Chute, MD, Keith M Sullivan, MD, Rachel Neuwirth, Patricia H Davis, Linda M. Sutton, Russell D Anderson, Nelson Chao, David A. Rizzieri, MD

Blood (2008) 112 (11): 3325.

https://doi.org/10.1182/blood.V112.11.3325.3325

Published: 2008

NARROW

Randomized Phase 2 Open-Label Study of R-CHOP ± Bortezomib in Patients (Pts) with Untreated Non-Germinal Center B-Cell-like (Non-GCB) Subtype Diffuse Large Cell Lymphoma (DLBCL): Results from the Pyramid Trial (NCT00931918)

Mutation of NRAS but not KRAS significantly reduces myeloma sensitivity to single-agent bortezomib therapy

Suppression Of Uninvolved Immunoglobulin Has Significant Clinical Implication Including Predicting Relapse In Multiple Myeloma

Efficacy and Safety Of Three Bortezomib-Based Induction and Maintenance Regimens In Previously Untreated, Transplant-Ineligible Multiple Myeloma (MM) Patients (Pts): Final Results From The Randomized, Phase 3b, US Community-Based UPFRONT Study (NCT00507416)

Risk of Second Primary Malignancies (SPMs) Following Bortezomib (Btz)-Based Therapy: Analysis of Four Phase 3 Randomized Controlled Trials in Previously Untreated or Relapsed Multiple Myeloma (MM)

Patient-Reported Quality of Life (QoL) in Elderly, Newly Diagnosed Multiple Myeloma (MM) Patients Receiving Bortezomib-Based Combinations: Results From All Randomized Patients in the Community-Based, Phase 3b UPFRONT Study

Efficacy and Safety of Three Bortezomib-Based Combinations in Elderly, Newly Diagnosed Multiple Myeloma Patients: Results From All Randomized Patients in the Community-Based, Phase 3b UPFRONT Study

Patient-Reported Quality of Life In Elderly, Newly Diagnosed Multiple Myeloma Patients Treated with Bortezomib-Based Regimens: Results From the Phase 3b UPFRONT Study

Herpes Zoster (HZ) Complicating Bortezomib Therapy of Relapsed/Refractory Indolent B-Cell and Mantle Cell Lymphoma: An Analysis of Two Phase II Trials.

Bortezomib In Combination with Rituximab, Cyclophosphamide, and Prednisone with or without Doxorubicin Followed by Rituximab Maintenance In Patients with Relapsed or Refractory Follicular Lymphoma: Results of a Phase 2 Study.

Hematological Testing Is Not Required with Every Dose of Bortezomib In Patients with Adequate Blood Counts at the Start of Each Cycle

Pharmacokinetics and Safety of Bortezomib In Patients with Advanced Malignancies and Varying Degrees of Liver Dysfunction: Results of the Phase 1 National Cancer Institute Organ Dysfunction Working Group Study NCI 6432

Phase 3b UPFRONT Study: Safety and Efficacy of Weekly Bortezomib Maintenance Therapy After Bortezomib-Based Induction Regimens In Elderly, Newly Diagnosed Multiple Myeloma Patients

Phase 3b UPFRONT Study: Interim Results From a Community Practice-Based Prospective Randomized Trial Evaluating Three Bortezomib-Based Regimens in Elderly, Newly Diagnosed Multiple Myeloma Patients.

Bortezomib Plus Melphalan and Prednisone as Induction Prior to Transplant or as Frontline Therapy for Non-Transplant Candidates in Patients with Previously Untreated Multiple Myeloma.

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American Society of Hematology

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American Society of Hematology

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