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Journal Articles

Selected Genomic Structural Variants Refine ELN-Based Prognostic Stratification of Patients with Acute Myeloid Leukemia and Normal Karyotype

Blood (2023) 142 (Supplement 1): 4317.

https://doi.org/10.1182/blood-2023-178599

Published: 2023

Journal Articles

Haploinsufficiency of Calreticulin Causes Dysregulation of Hematopoiesis and Results in a Myeloproliferative Phenotype in an in-Vivo Mouse Model

Niccolò Bartalucci, Laura Calabresi, Manjola Balliu, Danilo Tarantino, Simone Romagnoli, Alessio Enderti, Francesca Arciprete, Maria Zingariello, Christian A Di Buduo, Alessandra Balduini, Anna Rita Migliaccio, Paola Guglielmelli, Alessandro M Vannucchi

Blood (2022) 140 (Supplement 1): 9586–9587.

https://doi.org/10.1182/blood-2022-162537

Published: 2022

Journal Articles

Molecular Characterization of Response/Loss-of-Response to Ruxolitinib in Patients with Myelofibrosis

Paola Guglielmelli, Fiorenza Irushani Vanderwert, Simone Romagnoli, Giacomo Coltro, Giuseppe Gaetano Loscocco, Francesco Mannelli, Laura Calabresi, Giulia Gentili, Giada Rotunno, Niccolò Bartalucci, Valentina Boldrini, Emanuela Sant'Antonio, Danilo Tarantino, Marco Pieraccioli, Alessandro Vannucchi

Blood (2022) 140 (Supplement 1): 832–833.

https://doi.org/10.1182/blood-2022-156776

Published: 2022

Journal Articles

Single Cell Mutation Analysis Delineates Clonal Architecture in Leukemic Transformation of Myeloproliferative Neoplasms

Paola Guglielmelli, Laura Calabresi, Chiara Carretta, Giada Rotunno, Sandra Parenti, Simone Romagnoli, Selene Mallia, Niccolò Bartalucci, Sebastiano Rontauroli, Chiara Chiereghin, Sara Castellano, Francesco Mannelli, Matteo G. Della Porta, Rossella Manfredini, Alessandro Vannucchi

Blood (2021) 138 (Supplement 1): 56.

https://doi.org/10.1182/blood-2021-148315

Published: 2021

Journal Articles

Dysregulated IL-6/GP130/JAK Signaling in Calreticulin Mutated Myeloproliferative Neoplasms (MPN)

Manjola Balliu, PhD, Laura Calabresi, PhD, Niccolò Bartalucci, PhDBSc, Laura Maggi, PhD, Francesco Annunziato, PhD, Paola Guglielmelli, MD PhD, Alessandro M. Vannucchi, MD

Blood (2019) 134 (Supplement_1): 471.

https://doi.org/10.1182/blood-2019-123685

Published: 2019

Journal Articles

Involvement of RUNX1 Pathway Is a Common Event in the Leukemic Transformation of Chronic Myeloproliferative Neoplasms (MPNs)

Paola Guglielmelli, MD PhD, Niccolò Bartalucci, PhDBSc, Elisa Contini, PhD, Giada Rotunno, PhD, Annalisa Pacilli, PhD, Simone Romagnoli, BSc, Lara Mannelli, MD, Francesco Mannelli, MD, Giacomo Coltro, MD, Alessandro Pancrazzi, PhD, Valentina Ariu, BSci, Sara Fiaccabrino, Roberto Semeraro, Alberto Magi, PhD, Carmela Mannarelli, PhD, Francesca Gesullo, BSci, Chiara Paoli, PhD, Alessandro M. Vannucchi, MD

Blood (2019) 134 (Supplement_1): 2968.

https://doi.org/10.1182/blood-2019-129094

Published: 2019

Journal Articles

Calreticulin Ins5 and Del52 Mutations Impair Unfolded Protein and Oxidative Stress Responses in Hematopoietic Cells

Simona Salati, PhD, Elena Genovese, BSc, Zelia Prudente, BSc, PhD, Chiara Carretta, Niccolò Bartalucci, PhD BSc, Valentina Pennucci, PhD, Samantha Ruberti, BSc, PhD, Chiara Rossi, PharmD, Sebastiano Rontauroli, BSc, Carmela Mannarelli, PhD, Roberta Zini, BSc, PhD, Elisa Bianchi, BSc, PhD, Paola Guglielmelli, MD PhD, Enrico Tagliafico, MDPhD, Alessandro M. Vannucchi, MD, Rossella Manfredini, PhD

Blood (2018) 132 (Supplement 1): 4332.

https://doi.org/10.1182/blood-2018-99-112550

Published: 2018

Journal Articles

Absence of Calreticulin Phenocopies Cellular Abnormalities Induced By Calreticulin Exon-9 Mutation in Myeloproliferative Neoplasms

Laura Calabresi, PhD BSc, Manjola Balliu, PhD BSc, Niccolò Bartalucci, PhDBSc, Simona Salati, PhD, Laura Maggi, PhD, Francesco Annunziato, PhD, Rossella Manfredini, PhD, Paola Guglielmelli, MD PhD, Alessandro M. Vannucchi, MD

Blood (2018) 132 (Supplement 1): 1780.

https://doi.org/10.1182/blood-2018-99-113266

Published: 2018

Journal Articles

Large Genomic Alterations Occurring in the Transition from Chronic to Blast Phase of Chronic Myeloproliferative Neoplasms

Niccolò Bartalucci, PhD BSc, Alberto Magi, PhD, Elisa Contini, PhD, Davide Bolognini, PhD, Simone Romagnoli, BSc, Paola Guglielmelli, MD PhD, Alessandro M. Vannucchi, MD

Blood (2018) 132 (Supplement 1): 3028.

https://doi.org/10.1182/blood-2018-99-113048

Published: 2018

Journal Articles

Human GATA1 Driven By the Human Μicro LCR/β-Globin Promoter Rescues the Erythroid but Not the Megakaryocytic Phenotype Induced in Mice By the Gata1 low Mutation

Maria Zingariello, Laura Sancillo, Fabrizio Martelli, Rosa Alba Rana, Laura Calabresi, PhD BSc, Niccolò Bartalucci, PhDBSc, Alessandro M. Vannucchi, MD, George Stamatoyannopoulos, Anna Rita Migliaccio, PhD

Blood (2018) 132 (Supplement 1): 1042.

https://doi.org/10.1182/blood-2018-99-115970

Published: 2018

Journal Articles

Deletion of Calr By CRISPR/Cas9 Genome-Editing Mimics Abnormalities of Megakaryocytopoiesis Induced By Calr Del52 Mutation

Niccolò Bartalucci, PhDBSc, Laura Calabresi, BiSc, Manjola Balliu, PhD, Matteo Lulli, PhD, Giuditta Corbizi Fattori, BiSc, Paola Guglielmelli, MD PhD, Alessandro M. Vannucchi

Blood (2017) 130 (Supplement 1): 2945.

https://doi.org/10.1182/blood.V130.Suppl_1.2945.2945

Published: 2017

Journal Articles

Complete Inhibition of STAT5 Phosphorylation Is Achieved By Combination of JAK1/2 and PI3K/mTOR Inhibitors in in Vitro and In Vivo MPN Models

Niccolò Bartalucci, PhD, Laura Calabresi, BiSci, Serena Martinelli, BiSci, Manjola Balliu, PhD, Jean-Luc Villeval, PhD, Francesco Annunziato, PhD, Alessandro M. Vannucchi

Blood (2015) 126 (23): 2824.

https://doi.org/10.1182/blood.V126.23.2824.2824

Published: 2015

Journal Articles

The PI3K Specific Inhibitor BKM120 Results Effective and Synergizes With Ruxolitinib In Preclinical Models Of Myeloproliferative Neoplasms

Niccolò Bartalucci, PhD, Costanza Bogani, PhD, Serena Martinelli, BiSci, Carmela Mannarelli, BiSci, Jean-Luc Villeval, PhD, Alessandro M. Vannucchi, MD

Blood (2013) 122 (21): 1599.

https://doi.org/10.1182/blood.V122.21.1599.1599

Published: 2013

Journal Articles

Safety and efficacy of everolimus, a mTOR inhibitor, as single agent in a phase 1/2 study in patients with myelofibrosis

Blood (2011) 118 (8): 2069–2076.

https://doi.org/10.1182/blood-2011-01-330563

Published: 2011

Includes: Supplemental data

Journal Articles

Dysregulated Expression of MicroRNA-16 Contributes to Abnormal Erythropoiesis in Patients with Polycythemia Vera

Paola Guglielmelli, MD, Lorenzo Tozzi, BiSci, Costanza Bogani, PhD, Niccolo’ Bartalucci, BiSci, Simona Salati, PhD, Rossella Manfredini, MD, Alberto Bosi, MD, Alessandro M. Vannucchi, MD

Blood (2008) 112 (11): 179.

https://doi.org/10.1182/blood.V112.11.179.179

Published: 2008

NARROW

Selected Genomic Structural Variants Refine ELN-Based Prognostic Stratification of Patients with Acute Myeloid Leukemia and Normal Karyotype

Haploinsufficiency of Calreticulin Causes Dysregulation of Hematopoiesis and Results in a Myeloproliferative Phenotype in an in-Vivo Mouse Model

Molecular Characterization of Response/Loss-of-Response to Ruxolitinib in Patients with Myelofibrosis

Single Cell Mutation Analysis Delineates Clonal Architecture in Leukemic Transformation of Myeloproliferative Neoplasms

Dysregulated IL-6/GP130/JAK Signaling in Calreticulin Mutated Myeloproliferative Neoplasms (MPN)

Involvement of RUNX1 Pathway Is a Common Event in the Leukemic Transformation of Chronic Myeloproliferative Neoplasms (MPNs)

Calreticulin Ins5 and Del52 Mutations Impair Unfolded Protein and Oxidative Stress Responses in Hematopoietic Cells

Absence of Calreticulin Phenocopies Cellular Abnormalities Induced By Calreticulin Exon-9 Mutation in Myeloproliferative Neoplasms

Large Genomic Alterations Occurring in the Transition from Chronic to Blast Phase of Chronic Myeloproliferative Neoplasms

Human GATA1 Driven By the Human Μicro LCR/β-Globin Promoter Rescues the Erythroid but Not the Megakaryocytic Phenotype Induced in Mice By the Gata1 low Mutation

Deletion of Calr By CRISPR/Cas9 Genome-Editing Mimics Abnormalities of Megakaryocytopoiesis Induced By Calr Del52 Mutation

Complete Inhibition of STAT5 Phosphorylation Is Achieved By Combination of JAK1/2 and PI3K/mTOR Inhibitors in in Vitro and In Vivo MPN Models

The PI3K Specific Inhibitor BKM120 Results Effective and Synergizes With Ruxolitinib In Preclinical Models Of Myeloproliferative Neoplasms

Safety and efficacy of everolimus, a mTOR inhibitor, as single agent in a phase 1/2 study in patients with myelofibrosis

Dysregulated Expression of MicroRNA-16 Contributes to Abnormal Erythropoiesis in Patients with Polycythemia Vera

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American Society of Hematology

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