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Journal Articles

Molecular Characterization of Response/Loss-of-Response to Ruxolitinib in Patients with Myelofibrosis

Paola Guglielmelli, Fiorenza Irushani Vanderwert, Simone Romagnoli, Giacomo Coltro, Giuseppe Gaetano Loscocco, Francesco Mannelli, Laura Calabresi, Giulia Gentili, Giada Rotunno, Niccolò Bartalucci, Valentina Boldrini, Emanuela Sant'Antonio, Danilo Tarantino, Marco Pieraccioli, Alessandro Vannucchi

Blood (2022) 140 (Supplement 1): 832–833.

https://doi.org/10.1182/blood-2022-156776

Published: 2022

Journal Articles

Haploinsufficiency of Calreticulin Causes Dysregulation of Hematopoiesis and Results in a Myeloproliferative Phenotype in an in-Vivo Mouse Model

Niccolò Bartalucci, Laura Calabresi, Manjola Balliu, Danilo Tarantino, Simone Romagnoli, Alessio Enderti, Francesca Arciprete, Maria Zingariello, Christian A Di Buduo, Alessandra Balduini, Anna Rita Migliaccio, Paola Guglielmelli, Alessandro M Vannucchi

Blood (2022) 140 (Supplement 1): 9586–9587.

https://doi.org/10.1182/blood-2022-162537

Published: 2022

Journal Articles

Single Cell Mutation Analysis Delineates Clonal Architecture in Leukemic Transformation of Myeloproliferative Neoplasms

Paola Guglielmelli, Laura Calabresi, Chiara Carretta, Giada Rotunno, Sandra Parenti, Simone Romagnoli, Selene Mallia, Niccolò Bartalucci, Sebastiano Rontauroli, Chiara Chiereghin, Sara Castellano, Francesco Mannelli, Matteo G. Della Porta, Rossella Manfredini, Alessandro Vannucchi

Blood (2021) 138 (Supplement 1): 56.

https://doi.org/10.1182/blood-2021-148315

Published: 2021

Journal Articles

Dysregulated IL-6/GP130/JAK Signaling in Calreticulin Mutated Myeloproliferative Neoplasms (MPN)

Manjola Balliu, PhD, Laura Calabresi, PhD, Niccolò Bartalucci, PhDBSc, Laura Maggi, PhD, Francesco Annunziato, PhD, Paola Guglielmelli, MD PhD, Alessandro M. Vannucchi, MD

Blood (2019) 134 (Supplement_1): 471.

https://doi.org/10.1182/blood-2019-123685

Published: 2019

Journal Articles

Human GATA1 Driven By the Human Μicro LCR/β-Globin Promoter Rescues the Erythroid but Not the Megakaryocytic Phenotype Induced in Mice By the Gata1 low Mutation

Maria Zingariello, Laura Sancillo, Fabrizio Martelli, Rosa Alba Rana, Laura Calabresi, PhD BSc, Niccolò Bartalucci, PhDBSc, Alessandro M. Vannucchi, MD, George Stamatoyannopoulos, Anna Rita Migliaccio, PhD

Blood (2018) 132 (Supplement 1): 1042.

https://doi.org/10.1182/blood-2018-99-115970

Published: 2018

Journal Articles

Absence of Calreticulin Phenocopies Cellular Abnormalities Induced By Calreticulin Exon-9 Mutation in Myeloproliferative Neoplasms

Laura Calabresi, PhD BSc, Manjola Balliu, PhD BSc, Niccolò Bartalucci, PhDBSc, Simona Salati, PhD, Laura Maggi, PhD, Francesco Annunziato, PhD, Rossella Manfredini, PhD, Paola Guglielmelli, MD PhD, Alessandro M. Vannucchi, MD

Blood (2018) 132 (Supplement 1): 1780.

https://doi.org/10.1182/blood-2018-99-113266

Published: 2018

Journal Articles

Deletion of Calr By CRISPR/Cas9 Genome-Editing Mimics Abnormalities of Megakaryocytopoiesis Induced By Calr Del52 Mutation

Niccolò Bartalucci, PhDBSc, Laura Calabresi, BiSc, Manjola Balliu, PhD, Matteo Lulli, PhD, Giuditta Corbizi Fattori, BiSc, Paola Guglielmelli, MD PhD, Alessandro M. Vannucchi

Blood (2017) 130 (Supplement 1): 2945.

https://doi.org/10.1182/blood.V130.Suppl_1.2945.2945

Published: 2017

Journal Articles

Complete Inhibition of STAT5 Phosphorylation Is Achieved By Combination of JAK1/2 and PI3K/mTOR Inhibitors in in Vitro and In Vivo MPN Models

Niccolò Bartalucci, PhD, Laura Calabresi, BiSci, Serena Martinelli, BiSci, Manjola Balliu, PhD, Jean-Luc Villeval, PhD, Francesco Annunziato, PhD, Alessandro M. Vannucchi

Blood (2015) 126 (23): 2824.

https://doi.org/10.1182/blood.V126.23.2824.2824

Published: 2015

Journal Articles

A Greater Mutational Complexity May Contribute to the Differential Prognostic Impact of Type 1/Type 1-like Versus Type 2/Type2-like Calreticulin Mutations in Primary Myelofibrosis

Paola Guglielmelli, MD PhD, Giada Rotunno, MSc, Tiziana Fanelli, MSc, Annalisa Pacilli, PhD, Laura Calabresi, BiSci, Alessandro Pancrazzi, BS, Alessandro M. Vannucchi

Blood (2015) 126 (23): 1627.

https://doi.org/10.1182/blood.V126.23.1627.1627

Published: 2015

NARROW

Molecular Characterization of Response/Loss-of-Response to Ruxolitinib in Patients with Myelofibrosis

Haploinsufficiency of Calreticulin Causes Dysregulation of Hematopoiesis and Results in a Myeloproliferative Phenotype in an in-Vivo Mouse Model

Single Cell Mutation Analysis Delineates Clonal Architecture in Leukemic Transformation of Myeloproliferative Neoplasms

Dysregulated IL-6/GP130/JAK Signaling in Calreticulin Mutated Myeloproliferative Neoplasms (MPN)

Human GATA1 Driven By the Human Μicro LCR/β-Globin Promoter Rescues the Erythroid but Not the Megakaryocytic Phenotype Induced in Mice By the Gata1 low Mutation

Absence of Calreticulin Phenocopies Cellular Abnormalities Induced By Calreticulin Exon-9 Mutation in Myeloproliferative Neoplasms

Deletion of Calr By CRISPR/Cas9 Genome-Editing Mimics Abnormalities of Megakaryocytopoiesis Induced By Calr Del52 Mutation

Complete Inhibition of STAT5 Phosphorylation Is Achieved By Combination of JAK1/2 and PI3K/mTOR Inhibitors in in Vitro and In Vivo MPN Models

A Greater Mutational Complexity May Contribute to the Differential Prognostic Impact of Type 1/Type 1-like Versus Type 2/Type2-like Calreticulin Mutations in Primary Myelofibrosis

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American Society of Hematology

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American Society of Hematology

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