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Journal Articles

Ceramide-induced integrated stress response overcomes Bcl-2 inhibitor resistance in acute myeloid leukemia

Alexander C. Lewis, Victoria S. Pope, Melinda N. Tea, Manjun Li, Gus O. Nwosu, Thao M. Nguyen, Craig T. Wallington-Beddoe, Paul A. B. Moretti, Dovile Anderson, Darren J. Creek, Maurizio Costabile, Saira R. Ali, Chloe A. L. Thompson-Peach, B. Kate Dredge, Andrew G. Bert, Gregory J. Goodall, Paul G. Ekert, Anna L. Brown, Richard D’Andrea, Nirmal Robinson, Melissa R. Pitman, Daniel Thomas, David M. Ross, Briony L. Gliddon, Jason A. Powell, Stuart M. Pitson
Journal: Blood
Blood (2022) 139 (26): 3737–3751.
https://doi.org/10.1182/blood.2021013277
Published: 2022
Includes: Supplemental data
Journal Articles

Final Results of a Phase 2 Study of Sotatercept (ACE-011) for Anemia of MPN-Associated Myelofibrosis

Prithviraj Bose, Lucia Masarova, Naveen Pemmaraju, Sharon D. Bledsoe, Naval Daver, Elias J. Jabbour, Tapan M. Kadia, Zeev E. Estrov, Steven M. Kornblau, Michael Andreeff, Jorge E. Cortes, Nitin Jain, Gautam Borthakur, Yesid Alvarado, Julie Huynh-Lu, Madeleine M. Nguyen-Cao, Mary Ann Richie, Mackenzie H. Dobbins, Selene Andrea McCrackin, Lingsha Zhou, Sherry A. Pierce, Xuemei Wang, Allison M. Pike, Guillermo Garcia-Manero, Hagop Kantarjian, Srdan Verstovsek
Journal: Blood
Blood (2021) 138 (Supplement 1): 144.
https://doi.org/10.1182/blood-2021-150908
Published: 2021
Journal Articles

S100a8/S100a9-Emmprin-Vegfa Axis Initiated By Tet2 -Deficient Immune Cells Exacerbates Lung Cancer Progression through Promotion of Angiogenesis

Yen T. M. Nguyen, Manabu Fujisawa, Tran B. Nguyen, Yasuhito Suehara, Tatsuhiro Sakamoto, Ryota Matsuoka, Yoshiaki Abe, Kota Fukumoto, Keiichiro Hattori, Masayuki Noguchi, Daisuke Matsubara, Shigeru Chiba, Mamiko Sakata-Yanagimoto
Journal: Blood
Blood (2021) 138 (Supplement 1): 3276.
https://doi.org/10.1182/blood-2021-151723
Published: 2021
Journal Articles

Myeloid lncRNA LOUP mediates opposing regulatory effects of RUNX1 and RUNX1-ETO in t(8;21) AML

Bon Q. Trinh, Simone Ummarino, Yanzhou Zhang, Alexander K. Ebralidze, Mahmoud A. Bassal, Tuan M. Nguyen, Gerwin Heller, Rory Coffey, Danielle E. Tenen, Emiel van der Kouwe, Emiliano Fabiani, Carmelo Gurnari, Chan-Shuo Wu, Vladimir Espinosa Angarica, Henry Yang, Sisi Chen, Hong Zhang, Abby R. Thurm, Francisco Marchi, Elena Levantini, Philipp B. Staber, Pu Zhang, Maria Teresa Voso, Pier Paolo Pandolfi, Susumu S. Kobayashi, Li Chai, Annalisa Di Ruscio, Daniel G. Tenen
Journal: Blood
Blood (2021) 138 (15): 1331–1344.
https://doi.org/10.1182/blood.2020007920
Published: 2021
Includes: Supplemental data
Journal Articles

Low CD19 Antigen Density Diminishes Efficacy of CD19 CAR T Cells and Can be Overcome By Rational Redesign of CAR Signaling Domains

Robbie G. Majzner, MD, Skyler P. Rietberg, Louai Labanieh, Elena Sotillo, PhD, Evan W. Weber, PhD, Rachel C. Lynn, PhD, Johanna L. Theruvath, MD, Constance M. Yuan, MD PhD, Peng Xu, MD, Sang M. Nguyen, BS, Nirali N. Shah, MD, Maryalice Stetler-Stevenson, MD PhD, Terry J. Fry, MD, Daniel W. Lee, MD, Crystal L. Mackall, MD
Journal: Blood
Blood (2018) 132 (Supplement 1): 963.
https://doi.org/10.1182/blood-2018-99-115558
Published: 2018
Journal Articles

Modulation of CD22 Antigen Density Improves Efficacy of CD22 Chimeric Antigen Receptor (CAR) T Cells Against CD22 lo B-Lineage Leukemia and Lymphoma

Sneha Ramakrishna, MD, Sang M Nguyen, BS, Haiying Qin, MS, Steven L Highfill, PhD, Ira Kraft, John Shern, MD, Zachary Walsh, Dimiter Dimitrov, PhD, Terry J Fry, MD
Journal: Blood
Blood (2017) 130 (Supplement 1): 3894.
https://doi.org/10.1182/blood.V130.Suppl_1.3894.3894
Published: 2017
Journal Articles

Novel CD19/CD22 Bicistronic Chimeric Antigen Receptors Outperform Single or Bivalent Cars in Eradicating CD19 + CD22 + , CD19 - , and CD22 - Pre-B Leukemia

Haiying Qin, MS, Sang M Nguyen, BS, Sneha Ramakrishna, MD, Samiksha Tarun, MSc, Lila Yang, BS, Nicholas Peter Verdini, BS, Waleed Haso, MS, Terry J. Fry, MD
Journal: Blood
Blood (2017) 130 (Supplement 1): 810.
https://doi.org/10.1182/blood.V130.Suppl_1.810.810
Published: 2017
Journal Articles

Peripheral blood harvest of unaffected CD34+ CD38- hematopoietic precursors in paroxysmal nocturnal hemoglobinuria

GM Prince, M Nguyen, HM Lazarus, RA Brodsky, LW Terstappen, ME Medof
Journal: Blood
Blood (1995) 86 (9): 3381–3386.
https://doi.org/10.1182/blood.V86.9.3381.bloodjournal8693381
Published: 1995
Journal Articles

The "common stem cell" hypothesis reevaluated: human fetal bone marrow contains separate populations of hematopoietic and stromal progenitors

EK Waller, J Olweus, F Lund-Johansen, S Huang, M Nguyen, GR Guo, L Terstappen
Journal: Blood
Blood (1995) 85 (9): 2422–2435.
https://doi.org/10.1182/blood.V85.9.2422.bloodjournal8592422
Published: 1995