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Journal Articles

Selective targeting of sumoylation disrupts mitochondrial homeostasis via TRAP1 to suppress growth of non-Hodgkin lymphoma (NHL) B-cells

Vi Lam, Tingting Liu, Haifeng Shen, Olga Danilova, Katarzyna Dabrowska, Sonia Rodriguez-Rodriguez, Courtney Jones, Martina Cusan, Angelo D'Alessandro, Lapo Alinari, Lili Wang, Tycel Phillips, Patrick Pirrotte, Zheng Xia, Alexey Danilov

Blood (2025) 146 (Supplement 1): 5087.

https://doi.org/10.1182/blood-2025-5087

Published: 2025

Journal Articles

Dara-vd vs vrd: A breakthrough in newly diagnosed multiple myeloma treatment — superior survival and safety profiles

Blood (2025) 146 (Supplement 1): 7583.

https://doi.org/10.1182/blood-2025-7583

Published: 2025

Journal Articles

Integrated single-cell RNA sequencing and TCR profiling identifies immune drivers of severe early toxicity in CLL patients treated with idelalisib

Saurabh Yadav, Lu Yang, Zunqiu Wang, Binu Kandathilparambil Sasi, Stacey Fernandes, John-Hanson Machado, Samantha Shupe, Ignaty Leshchiner, Lili Wang, Jennifer Brown

Blood (2025) 146 (Supplement 1): 2103.

https://doi.org/10.1182/blood-2025-2103

Published: 2025

Journal Articles

Harnessing repressive LEF1/β-catenin complexes to overcome drug resistance in chronic lymphocytic leukemia

Kadriye Nehir Cosgun, Takeshi Ito, Mark Robinson, Esma Fera, Pranav Mishra, Jodi Forward, Prajish Iyer, Lili Wang, Tiziana Vaisitti, Silvia Deaglio, Maike Buchner, Hai-Hui Xue, Matthew S Davids, Markus Müschen

Blood (2025) 146 (Supplement 1): 5659.

https://doi.org/10.1182/blood-2025-5659

Published: 2025

Journal Articles

MGA loss promotes mitochondrial structure changes and redox adaptation in richter's transformation

Prajish Iyer, Girish Venkataraman, Joo Song, Oliche Brown, Dalmas Odhiambo, Wing Chan, Tanya Siddiqi, Steven Rosen, Alexey Danilov, Lili Wang

Blood (2025) 146 (Supplement 1): 5655.

https://doi.org/10.1182/blood-2025-5655

Published: 2025

Journal Articles

Integrating Metabolomics and Molecular Pathways to Uncover Therapeutic Vulnerabilities in Richter's Transformation

Prajish Iyer, Brian Jiang, Girish Venkataraman, Joo Y. Song, Wing Chung Chan, Tanya Siddiqi, Steven T. Rosen, Alexey Danilov, Antje Gohla, Lili Wang

Blood (2024) 144 (Supplement 1): 760.

https://doi.org/10.1182/blood-2024-199843

Published: 2024

Journal Articles

Impaired Response to Oxidative DNA Damage Underlies Genomic Instability in B-Cell Leukemia Driven By RPS15 Mutation

Blood (2024) 144 (Supplement 1): 758.

https://doi.org/10.1182/blood-2024-202115

Published: 2024

Journal Articles

Multiomic Discovery of Neopeptides from Non-Canonical ORFs on SF3B1 Mutation-Driven lncRNAs in Leukemia

Supriyo Bhattacharya, Mike Fernandez, Yiming Wu, Meiling Jin, Lili Wang

Blood (2024) 144 (Supplement 1): 1061.

https://doi.org/10.1182/blood-2024-208361

Published: 2024

Journal Articles

SF3B1 Mutation Drives Loss of Y Chromosome in Chronic Lymphocytic Leukemia

Mike Fernandez, Lei Yu, Qiong Jia, Xuesong Wang, Kevyn Hart, Zhenyu Jia, Ren-Jang Lin, Lili Wang

Blood (2024) 144 (Supplement 1): 46.

https://doi.org/10.1182/blood-2024-208209

Published: 2024

Journal Articles

Final Update of Safety, Efficacy and T-Cell Predictive Biomarkers from a Phase I Trial of Copanlisib+Nivolumab in Patients with Richter's Transformation (RT) or Transformed Non-Hodgkin Lymphoma (tNHL)

Geoffrey Shouse, Leslie Popplewell, Alex Muir, Tanya Siddiqi, Jasmine Zain, Alex F. Herrera, Olga Danilova, Stephen E Spurgeon, Lili Wang, Adam S Kittai, Lu Chen, Matthew S. Davids, Alexey V. Danilov

Blood (2024) 144 (Supplement 1): 4484.

https://doi.org/10.1182/blood-2024-209610

Published: 2024

Journal Articles

Beyond CLL Progression: Unveiling Th17 and Th2 T Cell Subsets As Predictors of Pembrolizumab Response in Richter's Transformation

Prajish Iyer, Lu Yang, Sutapa Sinha, Miles Del Busso, Zhi-Zhang Yang, Hyojin Kim, Charla Secreto, Yucai Wang, Neil E. Kay, Stephen M Ansell, Wei Ding, Lili Wang

Blood (2023) 142 (Supplement 1): 1888.

https://doi.org/10.1182/blood-2023-181004

Published: 2023

Journal Articles

Safety, Efficacy and T-Cell Predictive Biomarkers in a Phase I Trial of Copanlisib+Nivolumab in Patients with Richter's Transformation (RT) or Transformed Non-Hodgkin Lymphoma (tNHL)

Geoffrey P. Shouse, Leslie L. Popplewell, Alex Muir, Tanya Siddiqi, Alex F. Herrera, Olga Danilova, Sandrine Puverel, Lili Wang, Adam S Kittai, Lu Chen, Matthew S Davids, Alexey Danilov

Blood (2023) 142 (Supplement 1): 1730.

https://doi.org/10.1182/blood-2023-182559

Published: 2023

Journal Articles

Proteogenomic Features Define Novel Subtypes of Mantle Cell Lymphoma

Yuting Yan, Xinzhou Ge, Jian Sun, Lei Yu, Qunling Zhang, Ying Yu, Zhenyu Jia, Dehui Zou, Jessica Li, Lugui Qiu, Lili Wang, Shuhua Yi

Blood (2023) 142 (Supplement 1): 4368.

https://doi.org/10.1182/blood-2023-190838

Published: 2023

Journal Articles

RNA Splicing Factor Mutations Drive Aberrant Canonical and Cryptic Circular RNA Biogenesis in Leukemia

Mike Fernandez, Meiling Jin, Qiong Jia, Yiming Wu, Kevyn Hart, Emilee Bargoma, Joseph Pangallo, Robert K. Bradley, Omar Abdel-Wahab, Zhenyu Jia, Ren-Jang Lin, Lili Wang

Blood (2023) 142 (Supplement 1): 1395.

https://doi.org/10.1182/blood-2023-174135

Published: 2023

Journal Articles

Glycerolipid Metabolism Via the MGA-MYC-NME1-PGP Axis As a Key Regulator of Oxidative Phosphorylation in Richter's Transformation

Prajish Iyer, Brian Jiang, Girish Venkataraman, Joo Y Song, Tanya Siddiqi, Steven T. Rosen, Alexey Danilov, Lili Wang

Blood (2023) 142 (Supplement 1): 79.

https://doi.org/10.1182/blood-2023-179427

Published: 2023

Journal Articles

Individualized Dosing of Anti-Thymocyte Globulin Led to Reduced CMV/EBV Reactivation and Superior Overall Survival in Adult Unmanipulated Haploidentical Peripheral Blood Stem Cell Transplantation: A Prospective Phase II Study

Haitao Wang, Liping Dou, Lili Wang, Bo Peng, Nan Wang, Yingxin Zhao, Jishan Du, Daihong Liu

Blood (2022) 140 (Supplement 1): 4753–4754.

https://doi.org/10.1182/blood-2022-158994

Published: 2022

Journal Articles

A Phase I Trial of PI3Kαδ Inhibitor Copanlisib in Combination with Nivolumab in Patients with Richter's Transformation (RT) or Transformed Non-Hodgkin Lymphoma (tNHL)

Geoffrey Shouse, Tanya Siddiqi, Leslie L. Popplewell, Alexandra Muir, Ivana Melgar, Kirsten Orand, Brandy Gonzalez, Sandrine Puverel, Lili Wang, Adam S Kittai, Lu Chen, Matthew S. Davids, Alexey V Danilov

Blood (2022) 140 (Supplement 1): 6633–6634.

https://doi.org/10.1182/blood-2022-160157

Published: 2022

Journal Articles

Disrupting MGA-MYC Driven Metabolic Reprogramming in Richter's Syndrome Pre-Clinical Models Via Novel Therapeutic Approaches

Prajish Iyer, Bo Zhang, Tingting Liu, Meiling Jin, Kevyn Hart, Joo Y. Song, Wing C Chan, Tanya Siddiqi, Alexey V Danilov, Steve T Rosen, Lili Wang

Blood (2022) 140 (Supplement 1): 9842–9843.

https://doi.org/10.1182/blood-2022-162664

Published: 2022

Journal Articles

Nedd8-Activating Enzyme Inhibition Enhances Anti-Tumor Immunity and PD1 Blockade in In Vivo lymphoma Models

Xiaoguang Wang, Vi Lam, Dan Vuong, Tingting Liu, Olga Danilova, Tanya Siddiqi, Allison J Berger, Lili Wang, Alexey V. Danilov

Blood (2021) 138 (Supplement 1): 2414.

https://doi.org/10.1182/blood-2021-146349

Published: 2021

Journal Articles

MGA deletion Leads to Richter's Transformation Via NME1

Prajish Iyer, Bo Zhang, Tingting Liu, Meiling Jin, Kevyn Hart, Joo Y. Song, John Chan, Raju Pillai, Tanya Siddiqi, Alexey V. Danilov, Steven T. Rosen, Lili Wang

Blood (2021) 138 (Supplement 1): 252.

https://doi.org/10.1182/blood-2021-148953

Published: 2021

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Selective targeting of sumoylation disrupts mitochondrial homeostasis via TRAP1 to suppress growth of non-Hodgkin lymphoma (NHL) B-cells

Dara-vd vs vrd: A breakthrough in newly diagnosed multiple myeloma treatment — superior survival and safety profiles

Integrated single-cell RNA sequencing and TCR profiling identifies immune drivers of severe early toxicity in CLL patients treated with idelalisib

Harnessing repressive LEF1/β-catenin complexes to overcome drug resistance in chronic lymphocytic leukemia

MGA loss promotes mitochondrial structure changes and redox adaptation in richter's transformation

Integrating Metabolomics and Molecular Pathways to Uncover Therapeutic Vulnerabilities in Richter's Transformation

Impaired Response to Oxidative DNA Damage Underlies Genomic Instability in B-Cell Leukemia Driven By RPS15 Mutation

Multiomic Discovery of Neopeptides from Non-Canonical ORFs on SF3B1 Mutation-Driven lncRNAs in Leukemia

SF3B1 Mutation Drives Loss of Y Chromosome in Chronic Lymphocytic Leukemia

Final Update of Safety, Efficacy and T-Cell Predictive Biomarkers from a Phase I Trial of Copanlisib+Nivolumab in Patients with Richter's Transformation (RT) or Transformed Non-Hodgkin Lymphoma (tNHL)

Beyond CLL Progression: Unveiling Th17 and Th2 T Cell Subsets As Predictors of Pembrolizumab Response in Richter's Transformation

Safety, Efficacy and T-Cell Predictive Biomarkers in a Phase I Trial of Copanlisib+Nivolumab in Patients with Richter's Transformation (RT) or Transformed Non-Hodgkin Lymphoma (tNHL)

Proteogenomic Features Define Novel Subtypes of Mantle Cell Lymphoma

RNA Splicing Factor Mutations Drive Aberrant Canonical and Cryptic Circular RNA Biogenesis in Leukemia

Glycerolipid Metabolism Via the MGA-MYC-NME1-PGP Axis As a Key Regulator of Oxidative Phosphorylation in Richter's Transformation

Individualized Dosing of Anti-Thymocyte Globulin Led to Reduced CMV/EBV Reactivation and Superior Overall Survival in Adult Unmanipulated Haploidentical Peripheral Blood Stem Cell Transplantation: A Prospective Phase II Study

A Phase I Trial of PI3Kαδ Inhibitor Copanlisib in Combination with Nivolumab in Patients with Richter's Transformation (RT) or Transformed Non-Hodgkin Lymphoma (tNHL)

Disrupting MGA-MYC Driven Metabolic Reprogramming in Richter's Syndrome Pre-Clinical Models Via Novel Therapeutic Approaches

Nedd8-Activating Enzyme Inhibition Enhances Anti-Tumor Immunity and PD1 Blockade in In Vivo lymphoma Models

MGA deletion Leads to Richter's Transformation Via NME1

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