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Komal Kumar Javarappa
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Journal Articles

Predictors of Response and Rational Combinations for the Novel MCL-1 Inhibitor MIK665 in Acute Myeloid Leukemia

Joseph Saad, Rhiannon Newman, Elmira Khabusheva, Sofia Aakko, Eric Durand, Mahesh B. Tambe, Heikki Kuusanmäki, Alun Parsons, Juho J. Miettinen, Komal Kumar Javarappa, Nemo Ikonen, Mika Kontro, Kimmo Porkka, Heiko Maacke, Janghee Woo, Ensar Halilovic, Caroline A. Heckman
Journal: Blood
Blood (2024) 144 (Supplement 1): 1560.
https://doi.org/10.1182/blood-2024-207199
Published: 2024
Journal Articles

Erythroid/Megakaryocytic Differentiation Confers BCL-XL Dependency and Venetoclax Resistance in Acute Myeloid Leukemia

Olli Dufva, Heikki Kuusanmäki, Markus Vaha-Koskela, Aino-Maija Leppä, Jani Huuhtanen, Ida Vänttinen, Petra Johanna Nygren, Jay Klievink, Jonas Bouhlal, Petri Pölönen, Qi Zhang, Shady Adnan Awad, Cristina Mancebo, Joseph Saad, Juho J. Miettinen, Komal Kumar Javarappa, Sofia Aakko, Tanja Ruokoranta, Samuli Eldfors, Merja Heinäniemi, Ulla Wartiovaara-Kautto, Marina Konopleva, Mikko A Keränen, Kimmo Porkka, Krister Wennerberg, Mika Kontro, Caroline A. Heckman, Satu Mustjoki
Journal: Blood
Blood (2022) 140 (Supplement 1): 101–103.
https://doi.org/10.1182/blood-2022-158694
Published: 2022
Journal Articles

Deep Immune Profiling in Multiple Myeloma at Diagnosis and Under Lenalidomide Maintenance Therapy

Raija Helena Silvennoinen, Komal Kumar Javarappa, Sini Luoma, Philipp Sergeev, Tiina J Öhman, Markku Varjosalo, Pekka Anttila, Marjaana Säily, Anu Partanen, Marja Sankelo, Caroline A. Heckman
Journal: Blood
Blood (2021) 138 (Supplement 1): 1597.
https://doi.org/10.1182/blood-2021-149090
Published: 2021
Journal Articles

Azacytidine Inhibits Megakaryopoiesis Via the Induction of Immunogenic RNA Species and Activation of Type-I Interferon Signaling

Ujunwa Cynthia Okoye-Okafor, MS,PhD, Komal Kumar Javarappa, PhD, Dimitrios Tsallos, BSc(Hons),MSc, Joseph J Saad, MSc, BSc, Lumie Benard, Victor Thiruthuvanathan, M.S, Sally Cole, Madhuri Tatiparthy, M.S., Stephen Ruiz, B.Sc, Stefanie DeFronzo, Celine Pallaud, PhD, Pedro Marques Ramos, PhD, Amit Verma, MBBS, Aditi Shastri, MD, Caroline A Heckman, PhD, Britta Will, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 1280.
https://doi.org/10.1182/blood-2019-131461
Published: 2019
Journal Articles

BCR-ABL1 p190 in CML: A Minor Breakpoint with a Major Impact

Shady Adnan Awad, MD, Helena Hohtari, MD, Komal Kumar Javarappa, PhD, Tania Brandstoetter, Daehong Kim, Swapnil Potdar, MSc, Caroline A Heckman, PhD, Soili Kytölä, PhD, Kimmo Porkka, Eszter Doma, PhD, Veronika Sexl, MD PhD, Matti Kankainen, PhD, Satu Mustjoki, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 190.
https://doi.org/10.1182/blood-2019-126584
Published: 2019
Journal Articles

Eltrombopag Promotes Megakaryocyte Survival and Signaling in the Presence of Specific Cytotoxic Agents

Komal Kumar Javarappa, PhD, Dimitrios Tsallos, BSc(Hons), MSc, Bulat Zagidullin, MSc, Joseph J Saad, MSc, BSc, Jing Tang, PhD, Pedro Marques Ramos, PhD, Celine Pallaud, PhD, Caroline A Heckman, PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 3836.
https://doi.org/10.1182/blood-2018-99-118449
Published: 2018