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Juho Miettinen
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Journal Articles

Erythroid/megakaryocytic differentiation confers BCL-XL dependency and venetoclax resistance in acute myeloid leukemia

Heikki Kuusanmäki, Olli Dufva, Markus Vähä-Koskela, Aino-Maija Leppä, Jani Huuhtanen, Ida Vänttinen, Petra Nygren, Jay Klievink, Jonas Bouhlal, Petri Pölönen, Qi Zhang, Shady Adnan-Awad, Cristina Mancebo-Pérez, Joseph Saad, Juho Miettinen, Komal K. Javarappa, Sofia Aakko, Tanja Ruokoranta, Samuli Eldfors, Merja Heinäniemi, Kim Theilgaard-Mönch, Ulla Wartiovaara-Kautto, Mikko Keränen, Kimmo Porkka, Marina Konopleva, Krister Wennerberg, Mika Kontro, Caroline A. Heckman, Satu Mustjoki
Journal: Blood
Blood (2023) 141 (13): 1610–1625.
https://doi.org/10.1182/blood.2021011094
Published: 2023
Includes: Supplemental data
Journal Articles

Integration of Deep Multi-Omics Profiling Veals New Insights into the Biology of Poor-Risk Acute Myeloid Leukemia

Ana Rio-Machin, Pedro Casado-Izquierdo, Juho Miettinen, PhD, Findlay Bewicke-Copley, PhD MSc, BSc, Naeem Khan, PhD, Jonas Demeulemeester, Szilvia Krizsán, MD, Jiexin Zheng, Christopher Middleton, Wencheng Yin, William Grey, Farideh Miraki-Moud, PhD, Janet Matthews, Marianne Grantham, Kevin Rouault-Pierre, PhD, Krister Wennerberg, Alun Parsons, Hannah Armes, Karina EM Close, Doriana Di Bella, James Cavenagh, Sylvie D Freeman, Peter Van Loo, Csaba Bödör, PhD, Kimmo Porkka, Caroline A Heckman, PhD, Jun Wang, PhD, David Taussig, Dominique Bonnet, PhD, Jean-Baptiste Cazier, PhD, Pedro Cutillas, PhD, Jude Fitzgibbon, PhD
Journal: Blood
Blood (2020) 136 (Supplement 1): 39–40.
https://doi.org/10.1182/blood-2020-141345
Published: 2020
Journal Articles

In Vitro and in Vivo Activity of Melflufen in Amyloidosis

Ken Flanagan, PhD, Muntasir M Majumder, MSc, BPharm, Romika Kumari, PhD, Juho Miettinen, PhD, Ana Slipicevic, PhD, Sarah A. Holstein, MD PhD, Michelle L. Varney, MS, Minna Suvela, MSC, Fredrik Lehmann, PhD, Nina N. Nupponen, PhD, Caroline A Heckman, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 3100.
https://doi.org/10.1182/blood-2019-125952
Published: 2019
Journal Articles

Predictive Response Biomarkers for BET Inhibitors in AML

Joseph J Saad, MSc, BSc, Juho Miettinen, PhD, Dimitrios Tsallos, BSc(Hons),MSc, Samuli Eldfors, PhD, Mika Kontro, MD, Krister Wennerberg, PhD, Olli Kallioniemi, MD PhD, Kimmo Porkka, MD PhD, Jing Tang, PhD, Caroline A Heckman, PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 2749.
https://doi.org/10.1182/blood-2018-99-118363
Published: 2018