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Journal Articles

SPARC Stabilizes Integrin α4-VCAM-1 Interactions and Is Regulated By Intracellular Rac in NPM1 -Mutated AML

Driti Ashok, Dennis Raith, Martin Helmstädter, Geoffroy Andrieux, Séverine Kayser, Sangya Chatterjee, Judith Treiber, Khalid Shoumariyeh, Tim Struessmann, Valentin Wenger, Julian Rapp, Jesus Duque Afonso, Michael Lübbert, Robert Zeiser, Melanie Boerries, Justus Duyster, Tanja Nicole Hartmann

Blood (2024) 144 (Supplement 1): 1298.

https://doi.org/10.1182/blood-2024-205323

Published: 2024

Journal Articles

Patient-Reported Quality of Life Outcomes with Venetoclax-Based First-Line Combinations in CLL: An Analysis from the Phase 3 GAIA/CLL13 Trial

Blood (2024) 144 (Supplement 1): 3238.

https://doi.org/10.1182/blood-2024-198917

Published: 2024

Journal Articles

Early-life infection depletes preleukemic cells in a mouse model of hyperdiploid B-cell acute lymphoblastic leukemia

Ali Farrokhi, Tanmaya Atre, Samuel Salitra, Maryam Aletaha, Ana Citlali Márquez, Matthew Gynn, Mario Fidanza, Sumin Jo, Nina Rolf, Karen Simmons, Jesus Duque-Afonso, Michael L. Cleary, Alix E. Seif, Tobias Kollmann, Soren Gantt, Gregor S. D. Reid

Blood (2024) 144 (8): 809–821.

https://doi.org/10.1182/blood.2024025038

Published: 2024

Includes: Supplemental data

Journal Articles

CD49d Shapes B Cell Receptor Responsiveness and Tissue Distribution in an Aggressive Chronic Lymphocytic Leukemia Murine Model

Blood (2023) 142 (Supplement 1): 81.

https://doi.org/10.1182/blood-2023-179726

Published: 2023

Journal Articles

Genomic Determinants of Therapy Response in ETV6::RUNX1 Leukemia

Laura Oksa, Sanni Moisio, Khurram Maqbool, Hassan Foroughi-Asl, Roger Kramer, Atte Nikkilä, Kaisa Vepsäläinen, Jesus Duque-Afonso, Julia Hauer, Jessica Nordlund, Valtteri Wirta, Olli Lohi, Merja Heinäniemi

Blood (2023) 142 (Supplement 1): 2970.

https://doi.org/10.1182/blood-2023-188691

Published: 2023

Journal Articles

Long-Term Follow-up of AML Patients Undergoing Allogeneic Hematopoietic Stem Cell Transplantation after Primary Induction Failure

Miriam Mozaffari Jovein, Gabriele Ihorst, Jesus Duque Afonso, Ralph Wäsch, Claudia Wehr, Hartmut Bertz, Justus Duyster, Robert Zeiser, Jürgen Finke, Florian Scherer

Blood (2023) 142 (Supplement 1): 3588.

https://doi.org/10.1182/blood-2023-179103

Published: 2023

Journal Articles

Identification of Epigenetic Modifiers Essential for Growth and Survival of AML1/ETO-Positive Leukemia

Jesus Duque Afonso, Veratti Pia, Usama-Ur Rehman, Heike Herzog, Jan Mitschke, Gabriele Greve, Julian Eble, Bettina Berberich, Johanna Thomas, Milena Pantic, Miguel Waterhouse, Gaia Gentile, Olaf Heidenreich, Cornelius Miething, Michael Lübbert

Blood (2023) 142 (Supplement 1): 5687.

https://doi.org/10.1182/blood-2023-187372

Published: 2023

Journal Articles

Genetic and Pharmacological Inhibition of BTK Increases Dasatinib Sensitivity in Vitro and In Vivo Including CNS-Infiltrating E2A-PBX1 + /Pre-BCR + ALL Cells

Gaia Gentile, Teresa Poggio, Antonella Catalano, Minna Voutilainen, Marta Andrade-Martinez, Tobias Ma, Roman Sankowski, Lina Goncarenko, Stefan Tholen, Kyuho Han, David Morgens, Marco Prinz, Michael Luebbert, Peter Bronsert, Michael Bassik, Michael Cleary, Oliver Schilling, Merja Heinäniemi, Jesus Duque Afonso

Blood (2022) 140 (Supplement 1): 503–504.

https://doi.org/10.1182/blood-2022-162699

Published: 2022

Journal Articles

Comparison of Fludarabine/Melphalan (FluMel) with Fludarabine/Melphalan/BCNU or Thiotepa (FBM/FTM) in Patients with AML in First Complete Remission Undergoing Allogeneic Hematopoietic Stem Cell Transplantation - a Registry Study on Behalf of the EBMT Acute Leukemia Working Party

Blood (2022) 140 (Supplement 1): 2110–2112.

https://doi.org/10.1182/blood-2022-162277

Published: 2022

Journal Articles

The Fanconi Anemia-Associated Protein NIPA Is Essential for the Nuclear Abundance of FANCD2

Blood (2019) 134 (Supplement_1): 3741.

https://doi.org/10.1182/blood-2019-125973

Published: 2019

Journal Articles

Identification of a Novel Chromosomal Translocation t(11;16)(q23;q22) Fusing MLL to Enhancer of mRNA Decapping (EDC)-4 in Smoldering Acute Myeloid Leukemia

Heiko Becker, MD, Keisuke Kataoka, MD PhD, Gabriele Greve, Jesús Duque Afonso, MD, Tobias Ma, Sabine Bleul, Milena Pantic, PhD, Julia Schüler, DVM, PhD, Justus Duyster, MD, Michael L Cleary, MD, Seishi Ogawa, MD PhD, Michael Lübbert, MD

Blood (2016) 128 (22): 1696.

https://doi.org/10.1182/blood.V128.22.1696.1696

Published: 2016

Journal Articles

Oncogenic Role for the Lck/ZAP70/PLCG2 Signaling Pathway in Pre-B-ALL Pathogenesis

Jesus Duque-Afonso, MD, Michael C. Wei, MD PhD, Chiou-Hong Lin, PhD, Jue Feng, PhD, Corina Buechele, MD, Stephen Hon-Kit Wong, PhD, Michael C Bassik, PhD, Michael L. Cleary, MD

Blood (2015) 126 (23): 810.

https://doi.org/10.1182/blood.V126.23.810.810

Published: 2015

Journal Articles

MLL leukemia induction by genome editing of human CD34 + hematopoietic cells

Corina Buechele, Erin H. Breese, Dominik Schneidawind, Chiou-Hong Lin, Johan Jeong, Jesus Duque-Afonso, Stephen H. K. Wong, Kevin S. Smith, Robert S. Negrin, Matthew Porteus, Michael L. Cleary

Blood (2015) 126 (14): 1683–1694.

https://doi.org/10.1182/blood-2015-05-646398

Published: 2015

Includes: Supplemental data

Journal Articles

Comparative Studies of B Cell Precursor ALL Pathogenesis and Translational Biology Using a Conditional E2a-PBX1 Transgenic Mouse Model

Jesus Duque-Afonso, MD, Jue Feng, PhD, Florian Scherer, MD, Zhong Wang, PhD, Michael L. Cleary, MD

Blood (2014) 124 (21): 283.

https://doi.org/10.1182/blood.V124.21.283.283

Published: 2014

Journal Articles

Re-Expression of the AML1/ETO Target Gene LAT2/NTAL/LAB Results In Direct Interference with Myeloid Differentiation In AML1/ETO-Positive Cells

Jesus Duque-Afonso, Aitomi Essig, Leticia M Solari, Tobias Berg, MD, Heike L. Pahl, PhD, Michael Lübbert, MD, PhD

Blood (2010) 116 (21): 2474.

https://doi.org/10.1182/blood.V116.21.2474.2474

Published: 2010

Journal Articles

Pulmonary Graft-Versus-Host Disease After Reduced Toxicity Conditioning with Fludarabin, Carmustine and Melphalan Prior to Hematopoietic Stem Cell Transplantation

Jesus Duque-Afonso, Antje Prasse, Ralph Wäsch, Hartmut Bertz, Jurgen Finke, MD, Reinhard E Marks

Blood (2010) 116 (21): 1266.

https://doi.org/10.1182/blood.V116.21.1266.1266

Published: 2010

Journal Articles

Low Incidence of Pulmonary Graft-Versus-Host Disease in Older Patients After Reduced Toxicity Conditioning with FBM Prior to Hematopoietic Stem Cell Transplantation.

Jesus Duque-Afonso, Antje Prasse, Ralph M. Waesch, Hartmut Bertz, Jürgen Finke, Reinhard Marks

Blood (2009) 114 (22): 4660.

https://doi.org/10.1182/blood.V114.22.4660.4660

Published: 2009

Journal Articles

The AML1/ETO Target LAT2 Membrane Adaptor Molecule Is Regulated during Normal Monocytic Differentiation.

Jesus Duque-Afonso, MD, Leticia Solari, MD, Michael Luebbert, MD, PhD

Blood (2007) 110 (11): 2401.

https://doi.org/10.1182/blood.V110.11.2401.2401

Published: 2007

Journal Articles

Epigenetic Repression of the Adaptor Molecule LAT2 by the Leukemic Fusion Protein AML1/ETO.

Jesus Duque-Afonso, MD, Tobias Berg, MD, Olaf Heidenreich, PhD, Michael Luebbert, MD PhD

Blood (2007) 110 (11): 987.

https://doi.org/10.1182/blood.V110.11.987.987

Published: 2007

Journal Articles

AML1/ETO-Mediated Lysozyme Repression Is Independently Relieved by Inhibitors of DNA Methylation and Histone Deacetylation.

Rainer Claus, MD, Manfred Fliegauf, PhD, Michael Stock, PhD, Jesus Duque, Mateusz Kolanczyk, PhD, Michael Lübbert, MD PhD

Blood (2006) 108 (11): 4310.

https://doi.org/10.1182/blood.V108.11.4310.4310

Published: 2006

NARROW

SPARC Stabilizes Integrin α4-VCAM-1 Interactions and Is Regulated By Intracellular Rac in NPM1 -Mutated AML

Patient-Reported Quality of Life Outcomes with Venetoclax-Based First-Line Combinations in CLL: An Analysis from the Phase 3 GAIA/CLL13 Trial

Early-life infection depletes preleukemic cells in a mouse model of hyperdiploid B-cell acute lymphoblastic leukemia

CD49d Shapes B Cell Receptor Responsiveness and Tissue Distribution in an Aggressive Chronic Lymphocytic Leukemia Murine Model

Genomic Determinants of Therapy Response in ETV6::RUNX1 Leukemia

Long-Term Follow-up of AML Patients Undergoing Allogeneic Hematopoietic Stem Cell Transplantation after Primary Induction Failure

Identification of Epigenetic Modifiers Essential for Growth and Survival of AML1/ETO-Positive Leukemia

Genetic and Pharmacological Inhibition of BTK Increases Dasatinib Sensitivity in Vitro and In Vivo Including CNS-Infiltrating E2A-PBX1 + /Pre-BCR + ALL Cells

Comparison of Fludarabine/Melphalan (FluMel) with Fludarabine/Melphalan/BCNU or Thiotepa (FBM/FTM) in Patients with AML in First Complete Remission Undergoing Allogeneic Hematopoietic Stem Cell Transplantation - a Registry Study on Behalf of the EBMT Acute Leukemia Working Party

The Fanconi Anemia-Associated Protein NIPA Is Essential for the Nuclear Abundance of FANCD2

Identification of a Novel Chromosomal Translocation t(11;16)(q23;q22) Fusing MLL to Enhancer of mRNA Decapping (EDC)-4 in Smoldering Acute Myeloid Leukemia

Oncogenic Role for the Lck/ZAP70/PLCG2 Signaling Pathway in Pre-B-ALL Pathogenesis

MLL leukemia induction by genome editing of human CD34 + hematopoietic cells

Comparative Studies of B Cell Precursor ALL Pathogenesis and Translational Biology Using a Conditional E2a-PBX1 Transgenic Mouse Model

Re-Expression of the AML1/ETO Target Gene LAT2/NTAL/LAB Results In Direct Interference with Myeloid Differentiation In AML1/ETO-Positive Cells

Pulmonary Graft-Versus-Host Disease After Reduced Toxicity Conditioning with Fludarabin, Carmustine and Melphalan Prior to Hematopoietic Stem Cell Transplantation

Low Incidence of Pulmonary Graft-Versus-Host Disease in Older Patients After Reduced Toxicity Conditioning with FBM Prior to Hematopoietic Stem Cell Transplantation.

The AML1/ETO Target LAT2 Membrane Adaptor Molecule Is Regulated during Normal Monocytic Differentiation.

Epigenetic Repression of the Adaptor Molecule LAT2 by the Leukemic Fusion Protein AML1/ETO.

AML1/ETO-Mediated Lysozyme Repression Is Independently Relieved by Inhibitors of DNA Methylation and Histone Deacetylation.

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American Society of Hematology

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ASH Publications

American Society of Hematology

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