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Journal Articles

Evaluation of the Risk of Relapse and Survival Using a Conditional Survival Approach in 815 Multiple Myeloma Patients

Maximilian Schinke, Inga Promny, MD, Gabriele Ihorst, PhD, Johannes M. Waldschmidt, MD, Roland H. Mertelsmann, MD PhD, Justus Duyster, MD, Ralph M. Waesch, MD, Martin Schumacher, PhD, Monika Engelhardt, MD

Blood (2016) 128 (22): 5953.

https://doi.org/10.1182/blood.V128.22.5953.5953

Published: 2016

Journal Articles

Functional Geriatric Assessment (F-GA) in Multiple Myeloma Patients: Results from a Prospective Multicenter Study Group (DSMM) Trial and Changes from Baseline to Follow-up Assessment

Sophia Scheubeck, Sandra Maria Dold, M. Sc., Gabriele Ihorst, PhD, Alexander Zober, MD, Stefan J. Müller, Dipl.-Pharm., Christian Langer, MD, Wolfram Pönisch, Lars-Olof Mügge, MD, Stefan Knop, MD, Justus Duyster, MD, Martin Schumacher, PhD, Ralph M. Waesch, MD, Monika Engelhardt, MD

Blood (2016) 128 (22): 5627.

https://doi.org/10.1182/blood.V128.22.5627.5627

Published: 2016

Journal Articles

Treatment of Corticosteroid-Refractory Graft-Versus-Host Disease with Ruxolitinib in 95 Patients

Robert Zeiser, MD, Andreas Burchert, MD, Claudia Lengerke, MD, Mareike Verbeek, Kristina Maas-Bauer, MD, Stephan Metzelder, MD, Silvia Spoerl, MD, Markus Ditschkowski, MD, Matyas Ecsedi, MD, Katja Sockel, MD, Francis Ayuk, MD, Salem Ajib, MD, Flore Sicre de Fontbrune, MD, Il-Kang Na, MD, Livius Penter, MD, Udo Holtick, MD PhD, Dominik Wolf, MD, Esther Schuler, MD, Everett Meyer, MD PhD, Petya Apostolova, MD, Hartmut Bertz, MD, Reinhard Marks, Michael Luebbert, MD, Ralph M. Waesch, MD PhD, Christof Scheid, MD PhD, Friedrich Stölzel, MD, Rainer Ordemann, MD, Gesine Bug, MD, Guido Kobbe, MD, Robert Negrin, MD, Mats L Brune, Alexandros Spyridonidis, Annette Schmitt-Graeff, MD, Walter van der Velden, MD, Gerwin Huls, MD PhD, Stephan Mielke, MD, Goetz Ulrich Grigoleit, MD, Jurgen Kuball, MDPhD, Ryan P Flynn, PhD, Gabriele Ihorst, PhD, Jing Du, Bruce R. Blazar, MD, Renate Arnold, MD, Nicolaus Kröger, MD, Joerg Halter, MD, Gerard Socie, Dietrich Beelen, MD, Christian Peschel, MD, Andreas Neubauer, MD, Juergen Finke, MD, Justus Duyster, MD PhD, Nikolas von Bubnoff, MD

Blood (2015) 126 (23): 858.

https://doi.org/10.1182/blood.V126.23.858.858

Published: 2015

Journal Articles

Novel Patient Derived Multiple Myeloma Model Reflects Sensitivity Towards Anticancer Treatment in Multiple Myeloma Patients

Julia B. Schueler, DVM, PhD, Dagmar Wider, Kerstin Klingner, Gabrielle Melanie Siegers, PhD, Annette M May, MD, Johannes M. Waldschmidt, MD, Alexander Keller, MD, Justus Duyster, MD, Ralph M. Waesch, MD, Monika Engelhardt, MD

Blood (2015) 126 (23): 3004.

https://doi.org/10.1182/blood.V126.23.3004.3004

Published: 2015

Journal Articles

Impact of Comorbidities and Prospective Functional Geriatric Assessment Tools (CF-GA) As an Aide to Understand Outcome, Therapy Tolerance, Side Effects and Clinical Trial Eligibility in Multiple Myeloma (MM) Patients (pts)

Alexander Zober, MD, Mandy Möller, Sandra-Maria Dold, Gabriele Ihorst, PhD, Stefanie Hieke, PhD, Jochen Knaus, Milena Pantic, PhD, Barbara Deschler-Baier, MD, Stefan Knop, Hermann Einsele, Christian Langer, Lars-Olof Muegge, MD, Wolfram Poenisch, MD, Justus Duyster, MD PhD, Martin Schumacher, PhD, Ralph M. Waesch, MD PhD, Monika Engelhardt, MD PhD

Blood (2015) 126 (23): 5616.

https://doi.org/10.1182/blood.V126.23.5616.5616

Published: 2015

Journal Articles

Dissecting Stem Cell Proliferation and Differentiation In Association With The Central Cell Cycle Regulator APC/C Cdh1 In Vitro and In Vivo

Daniel Ewerth, Andrea Schmidts, Birgit Kuegelgen, Dagmar Wider, Julia Schüler, Monika Engelhardt, MD, Ralph M. Waesch, MD

Blood (2013) 122 (21): 2446.

https://doi.org/10.1182/blood.V122.21.2446.2446

Published: 2013

Journal Articles

The Tumor Suppressor APC/C Cdh1 and Its Role In Replication Stress and The Origin Of Genomic Instability

Julika Krohs, Dominik Schnerch, MD, Marie Follo, Julia Felthaus, Monika Engelhardt, MD, Ralph M. Waesch, MD

Blood (2013) 122 (21): 2489.

https://doi.org/10.1182/blood.V122.21.2489.2489

Published: 2013

Journal Articles

Significant Improvement Of Outcome In Adolescents and Young adults (AYAs) Aged 15-35 Years With Acute Lymphoblastic Leukemia (ALL) With a Pediatric Derived Adult ALL Protocol; Results Of 1529 AYAs In 2 Consecutive Trials Of The German Multicenter Study Group For Adult ALL (GMALL)

Blood (2013) 122 (21): 839.

https://doi.org/10.1182/blood.V122.21.839.839

Published: 2013

Journal Articles

Analysis of Mitosis In Acute Myeloid Leukemia Using Live-Cell Imaging.

Dominik Schnerch, Julia Felthaus, Lara Mentlein, Monika Engelhardt, Ralph M. Waesch, MD

Blood (2010) 116 (21): 3363.

https://doi.org/10.1182/blood.V116.21.3363.3363

Published: 2010

Journal Articles

Striking Anti-Multiple Myeloma (MM) Activity with the In Vitro Use of the Multikinase Inhibitor Sorafenib (S), Cytotoxic Synergy Between Bortezomib (B) and S, but Not Between B and Epigallocatechin-3-Gallate (EGCG; E) Enlarge the Present Knowledge In MM and Promise Novel Insights for Innovative Substance Exploitation In MM-Treatment

Josefina Udi, Dagmar Wider, Julie Catusse, Gabriele Ihorst, Dominik Schnerch, Marie Follo, Meike Burger, Ralph M. Waesch, MD, Monika Engelhardt

Blood (2010) 116 (21): 5020.

https://doi.org/10.1182/blood.V116.21.5020.5020

Published: 2010

Journal Articles

APC/C-Cdh1 as a Novel Regulator of Hematopoietic Stem Cell Differentiation.

Andrea Schmidts, Dagmar Wider, Julia Felthaus, Manuel Hein, Dominik Schnerch, Monika Engelhardt, Ralph M. Waesch, MD

Blood (2010) 116 (21): 1563.

https://doi.org/10.1182/blood.V116.21.1563.1563

Published: 2010

Journal Articles

Everolimus and Mycophenolate as GvHD Prophylaxis Results In Improved Control of Advanced Disease and Reduced Bacterial and Fungal Infectious Complications After Allogeneic Stem Cell Transplantation

Reinhard E Marks, Hartmut Bertz, Ralph M. Waesch, MD, Wolfgang Melchinger, Juergen Finke

Blood (2010) 116 (21): 1264.

https://doi.org/10.1182/blood.V116.21.1264.1264

Published: 2010

Journal Articles

Low Incidence of Pulmonary Graft-Versus-Host Disease in Older Patients After Reduced Toxicity Conditioning with FBM Prior to Hematopoietic Stem Cell Transplantation.

Jesus Duque-Afonso, Antje Prasse, Ralph M. Waesch, Hartmut Bertz, Jürgen Finke, Reinhard Marks

Blood (2009) 114 (22): 4660.

https://doi.org/10.1182/blood.V114.22.4660.4660

Published: 2009

Journal Articles

“Antitumor Activity of Novel Anti-MM Agents and Combinations, the Proteasome Inhibitor Bortezomib and Multikinase Inhibitor Sorafenib, Both Applied as Monotherapy and in Combination in NOD/SCID-IL2-Receptor-Gamma-chain −/− (NSG) Mice Using a Intratibial Tumor Dissemination approach”.

Julia Schüler, Dagmar Wider, Dietmar Pfeifer, Josefina Udi, Heinz-Herbert Fiebig, Ralph M. Waesch, Monika Engelhardt

Blood (2009) 114 (22): 4912.

https://doi.org/10.1182/blood.V114.22.4912.4912

Published: 2009

Journal Articles

Downregulation of the Cell-Cycle Regulating Ubiquitin-Ligase APC/C Cdh1 May Contribute to the Differentiation Block of AML1/Eto Positive AML.

Manuel Hein, Dominik Schnerch, Andrea Schmidts, Julia Felthaus, Dagmar Wider, Gabriele Ihorst, Monika Engelhardt, Ralph M. Waesch

Blood (2009) 114 (22): 5045.

https://doi.org/10.1182/blood.V114.22.5045.5045

Published: 2009

Journal Articles

Efficacy of a 3-Day, Low-Dose Treatment with 5-Azacytidine Followed by Donor Lymphocyte Infusions (DLI ) in Older AML/MDS Patients Relapsed after Allografting.

Michael Lübbert, Ralph M. Waesch, Reinhard Marks, Björn Rüter, Hartmut Bertz, Juergen Finke

Blood (2008) 112 (11): 3248.

https://doi.org/10.1182/blood.V112.11.3248.3248

Published: 2008

Journal Articles

Unscheduled Sister-Chromatid-Separation in the Presence of Spindle Disruption in Acute Myelogenous Leukemia

Dominik Schnerch, Julia Felthaus, Monika Engelhardt, Ralph M. Waesch, MD

Blood (2008) 112 (11): 3114.

https://doi.org/10.1182/blood.V112.11.3114.3114

Published: 2008

Journal Articles

Polo-Like Kinase-1 (Plk-1) Inhibitor BI 2536 Induces Mitotic Arrest and Apoptosis in Vivo: First Demonstration of Target Inhibition in the Bone Marrow of AML Patients

Kang-Hun Lee, MD, Richard F. Schlenk, MD, Gesine Bug, MD, Carsten Müller-Tidow, MD, Ralph M. Waesch, MD, David Nachbaur, MD, Peter Valent, MD, Gerd Munzert, MD, Frank Fleischer, PhD, Hartmut Dohner, MD, PhD, Pilar Garin-Chesa, PhD

Blood (2008) 112 (11): 2641.

https://doi.org/10.1182/blood.V112.11.2641.2641

Published: 2008

Journal Articles

Spindle Checkpoint Insufficiency in Acute Myeloid Leukemia.

Dominik Schnerch, Julia Felthaus, Monika Engelhardt, MD, Ralph M. Waesch, MD

Blood (2007) 110 (11): 873.

https://doi.org/10.1182/blood.V110.11.873.873

Published: 2007

Journal Articles

Spindle Checkpoint Insufficiency and Unscheduled APC-Dependent Proteolysis in Acute Myeloid Leukemia.

Dominik Schnerch, Julia Felthaus, Monika Engelhardt, Ralph M. Waesch

Blood (2006) 108 (11): 2082.

https://doi.org/10.1182/blood.V108.11.2082.2082

Published: 2006

NARROW

Evaluation of the Risk of Relapse and Survival Using a Conditional Survival Approach in 815 Multiple Myeloma Patients

Functional Geriatric Assessment (F-GA) in Multiple Myeloma Patients: Results from a Prospective Multicenter Study Group (DSMM) Trial and Changes from Baseline to Follow-up Assessment

Treatment of Corticosteroid-Refractory Graft-Versus-Host Disease with Ruxolitinib in 95 Patients

Novel Patient Derived Multiple Myeloma Model Reflects Sensitivity Towards Anticancer Treatment in Multiple Myeloma Patients

Impact of Comorbidities and Prospective Functional Geriatric Assessment Tools (CF-GA) As an Aide to Understand Outcome, Therapy Tolerance, Side Effects and Clinical Trial Eligibility in Multiple Myeloma (MM) Patients (pts)

Dissecting Stem Cell Proliferation and Differentiation In Association With The Central Cell Cycle Regulator APC/C Cdh1 In Vitro and In Vivo

The Tumor Suppressor APC/C Cdh1 and Its Role In Replication Stress and The Origin Of Genomic Instability

Significant Improvement Of Outcome In Adolescents and Young adults (AYAs) Aged 15-35 Years With Acute Lymphoblastic Leukemia (ALL) With a Pediatric Derived Adult ALL Protocol; Results Of 1529 AYAs In 2 Consecutive Trials Of The German Multicenter Study Group For Adult ALL (GMALL)

Analysis of Mitosis In Acute Myeloid Leukemia Using Live-Cell Imaging.

APC/C-Cdh1 as a Novel Regulator of Hematopoietic Stem Cell Differentiation.

Everolimus and Mycophenolate as GvHD Prophylaxis Results In Improved Control of Advanced Disease and Reduced Bacterial and Fungal Infectious Complications After Allogeneic Stem Cell Transplantation

Low Incidence of Pulmonary Graft-Versus-Host Disease in Older Patients After Reduced Toxicity Conditioning with FBM Prior to Hematopoietic Stem Cell Transplantation.

“Antitumor Activity of Novel Anti-MM Agents and Combinations, the Proteasome Inhibitor Bortezomib and Multikinase Inhibitor Sorafenib, Both Applied as Monotherapy and in Combination in NOD/SCID-IL2-Receptor-Gamma-chain −/− (NSG) Mice Using a Intratibial Tumor Dissemination approach”.

Downregulation of the Cell-Cycle Regulating Ubiquitin-Ligase APC/C Cdh1 May Contribute to the Differentiation Block of AML1/Eto Positive AML.

Efficacy of a 3-Day, Low-Dose Treatment with 5-Azacytidine Followed by Donor Lymphocyte Infusions (DLI ) in Older AML/MDS Patients Relapsed after Allografting.

Unscheduled Sister-Chromatid-Separation in the Presence of Spindle Disruption in Acute Myelogenous Leukemia

Polo-Like Kinase-1 (Plk-1) Inhibitor BI 2536 Induces Mitotic Arrest and Apoptosis in Vivo: First Demonstration of Target Inhibition in the Bone Marrow of AML Patients

Spindle Checkpoint Insufficiency in Acute Myeloid Leukemia.

Spindle Checkpoint Insufficiency and Unscheduled APC-Dependent Proteolysis in Acute Myeloid Leukemia.

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American Society of Hematology

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American Society of Hematology

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