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Journal Articles

Leukemic Cell-Intrinsic Innate Nucleic Acid Receptor Signaling Governs Efficacy of Hypomethylating Agents and Immunosurveillance in AML

Nadia El Khawanky, Yunus Barth, Tatiana Nedelko, Marc Rosenbaum, Christin Weiß, Stefan Enßle, Jürgen Ruland, Florian Bassermann, Simon M Heidegger

Blood (2023) 142 (Supplement 1): 1421.

https://doi.org/10.1182/blood-2023-182567

Published: 2023

Journal Articles

Negative Feedback Regulation of MAPK Signaling Is an Important Driver of CLL Progression

Lisa Brandmeier, Veronika Ecker, Martina Stumpf, Piero Giansanti, Aida Varela Moreira, Lisa Pfeuffer, Marcel Fens, Junyan Lu, Bernhard Küster, Thomas Engleitner, Simon Heidegger, Ingo Ringshausen, Thorsten Zenz, Clemens-Martin Wendtner, Markus Müschen, Jürgen Ruland, Maike Buchner

Blood (2022) 140 (Supplement 1): 9840–9841.

https://doi.org/10.1182/blood-2022-160103

Published: 2022

Journal Articles

Pathological RANK Signaling in Combination with TCL1 Drives a Multiple Myeloma-like Disease in Mice

Lisa Pfeuffer, Lisa Brandmeier, Nicole Beck, Katja Steiger, Clemens-Martin Wendtner, Jürgen Ruland, Maike Buchner

Blood (2022) 140 (Supplement 1): 606–607.

https://doi.org/10.1182/blood-2022-167394

Published: 2022

Journal Articles

Identification of Bacterial and Viral Consortia for the Production of Intestinal Microbiota-Derived Metabolites Associated with Protection in Allogeneic Stem Cell Transplantation Patients

Blood (2022) 140 (Supplement 1): 7619–7621.

https://doi.org/10.1182/blood-2022-157423

Published: 2022

Journal Articles

MondoA drives malignancy in B-ALL through enhanced adaptation to metabolic stress

Blood (2022) 139 (8): 1184–1197.

https://doi.org/10.1182/blood.2020007932

Published: 2022

Includes: Supplemental data

Journal Articles

Autophagy in mesenchymal progenitors protects mice against bone marrow failure after severe intermittent stress

Blood (2022) 139 (5): 690–703.

https://doi.org/10.1182/blood.2021011775

Published: 2022

Includes: Supplemental data

Journal Articles

Integrated genomic analyses of cutaneous T-cell lymphomas reveal the molecular bases for disease heterogeneity

Blood (2021) 138 (14): 1225–1236.

https://doi.org/10.1182/blood.2020009655

Published: 2021

Includes: Supplemental data

Journal Articles

Synergy of MALT1 and mTOR inhibition in DLBCL

Jürgen Ruland

Blood (2021) 137 (6): 724–725.

https://doi.org/10.1182/blood.2020008465

Published: 2021

Journal Articles

RIG-I Activation Is Critical for Responsiveness to Checkpoint Blockade

Simon Heidegger, MD, Alexander Wintges, Florian Stritzke, Katja Steiger, Paul-Albert Koenig, Thomas Engleitner, Julius Clemens Fischer, Vladimir Makarov, Christof Winter, Roland Rad, Marcel R.M. van den Brink, MD PhD, Jürgen Ruland, Florian Bassermann, MD PhD, Timothy Chan, Tobias Haas, MD, Hendrik Poeck, MD

Blood (2019) 134 (Supplement_1): 624.

https://doi.org/10.1182/blood-2019-128724

Published: 2019

Journal Articles

DUSP1/6 Inhibition Reduces Tumor Cells and Activates Immune Response in Chronic Lymphocytic Leukemia

Martina Braun, Veronika Ecker, MSc, Tanja Neumayer, Markus Muschen, MD, Jürgen Ruland, Maike Buchner, Dr.

Blood (2018) 132 (Supplement 1): 2857.

https://doi.org/10.1182/blood-2018-99-117052

Published: 2018

Journal Articles

Adaptation to Metabolic Stress By Mondoα in Common B-Cell Acute Lymphoblastic Leukemia

Alexandra Sipol, Andreas Petry, Erik Hameister, Agnes Görlach, Jürgen Ruland, Stefan Burdach, Poul Sorensen

Blood (2018) 132 (Supplement 1): 3888.

https://doi.org/10.1182/blood-2018-99-114014

Published: 2018

Journal Articles

SHIP1 Inhibition As Novel Therapeutic Approach in Chronic Lymphocytic Leukemia

Veronika Ecker, MSc, Martina Braun, Tanja Neumayer, Markus Muschen, MD, Jürgen Ruland, Maike Buchner, Dr.

Blood (2018) 132 (Supplement 1): 894.

https://doi.org/10.1182/blood-2018-99-117053

Published: 2018

Journal Articles

Tumor-Intrinsic RIG-I Signaling Promotes Anti-CTLA-4 Checkpoint Inhibitor-Mediated Anticancer Immunity

Simon Heidegger, MD, Alexander Wintges, Sarah Bek, Martina Schmickl, Jürgen Ruland, MD, Marcel R.M. van den Brink, MD PhD, Christian Peschel, MD, Tobias Haas, MD, Hendrik Poeck, MD

Blood (2017) 130 (Supplement 1): 693.

https://doi.org/10.1182/blood.V130.Suppl_1.693.693

Published: 2017

Journal Articles

The RIG-I Agonist 3pRNA Synergizes with Checkpoint Blockade in Cancer Immunotherapy

Simon Heidegger, MD, Diana Kreppel, Michael Bscheider, MD, Alexander Wintges, Sarah Bek, Martina Schmickl, Jürgen Ruland, MD, Christian Peschel, MD, Marcel van den Brink, MD, Tobias Haas, MD, Hendrik Poeck, MD

Blood (2015) 126 (23): 3436.

https://doi.org/10.1182/blood.V126.23.3436.3436

Published: 2015

Journal Articles

Constitutive gp130-JAK-STAT3 Signaling Induces a Plasma Cell Disorder Representing Genetic and Clinical Features of Human Myeloma – a Novel in Vivo Model for the Patient Subgroup Characterized By a STAT3 Target Gene Signature

Sabine Steidle, MD, Tobias Dechow, MD, Katharina Götze, Martina Rudelius, MD, Konstanze Pechloff, PhD, Kerstin Behnke, Lars Bullinger, MD PhD, Falko Fend, MD, Soberon Valeria, PhDstudent, Marc Schmidt-Supprian, PhD, Florian Bassermann, MD, Jürgen Ruland, MD, Christian Peschel, MD, Ulrich Keller, MD

Blood (2014) 124 (21): 648.

https://doi.org/10.1182/blood.V124.21.648.648

Published: 2014

Journal Articles

A Mouse Model for XLP-2 Disease Uncovers a Critical Function for IL-1beta and TNF in Driving Hyper-Inflammation

Philipp J. Jost, MD, Monica Yabal, PhD, Heiko Adler, PhD, Nathalie Knies, Christina Groß, Rune Busk Damgaard, Hirokazu Kanegane, MD PhD, Christian Peschel, MD, Andreas Strasser, PhD, Olaf Groß, Jürgen Ruland, MD, Mads Gyrd-Hansen, PhD

Blood (2014) 124 (21): 1403.

https://doi.org/10.1182/blood.V124.21.1403.1403

Published: 2014

Journal Articles

MCL-1 Critically Regulates Survival Of T-Lymphocyte Non-Hodgkin Lymphoma

Sabine Spinner, Kelly Gemma, PhD, Marco Herold, PhD, Konstanze Pechloff, PhD, Giuliano Crispatzu, Jürgen Ruland, MD, Marco Herling, MD, Christian Peschel, MD, Andreas Strasser, PhD, Philipp J. Jost, MD

Blood (2013) 122 (21): 4246.

https://doi.org/10.1182/blood.V122.21.4246.4246

Published: 2013

Journal Articles

Multiple ITAM-coupled NK-cell receptors engage the Bcl10/Malt1 complex via Carma1 for NF-κB and MAPK activation to selectively control cytokine production

Olaf Gross, Christina Grupp, Christian Steinberg, Stephanie Zimmermann, Dominikus Strasser, Nicole Hannesschläger, Wolfgang Reindl, Helena Jonsson, Hairong Huo, Dan R. Littman, Christian Peschel, Wayne M. Yokoyama, Anne Krug, Jürgen Ruland

Blood (2008) 112 (6): 2421–2428.

https://doi.org/10.1182/blood-2007-11-123513

Published: 2008

Journal Articles

Signaling crosstalk in DLBCL

Jürgen Ruland

Blood (2008) 111 (7): 3304.

https://doi.org/10.1182/blood-2008-01-133330

Published: 2008

NARROW

Leukemic Cell-Intrinsic Innate Nucleic Acid Receptor Signaling Governs Efficacy of Hypomethylating Agents and Immunosurveillance in AML

Negative Feedback Regulation of MAPK Signaling Is an Important Driver of CLL Progression

Pathological RANK Signaling in Combination with TCL1 Drives a Multiple Myeloma-like Disease in Mice

Identification of Bacterial and Viral Consortia for the Production of Intestinal Microbiota-Derived Metabolites Associated with Protection in Allogeneic Stem Cell Transplantation Patients

MondoA drives malignancy in B-ALL through enhanced adaptation to metabolic stress

Autophagy in mesenchymal progenitors protects mice against bone marrow failure after severe intermittent stress

Integrated genomic analyses of cutaneous T-cell lymphomas reveal the molecular bases for disease heterogeneity

Synergy of MALT1 and mTOR inhibition in DLBCL

RIG-I Activation Is Critical for Responsiveness to Checkpoint Blockade

DUSP1/6 Inhibition Reduces Tumor Cells and Activates Immune Response in Chronic Lymphocytic Leukemia

Adaptation to Metabolic Stress By Mondoα in Common B-Cell Acute Lymphoblastic Leukemia

SHIP1 Inhibition As Novel Therapeutic Approach in Chronic Lymphocytic Leukemia

Tumor-Intrinsic RIG-I Signaling Promotes Anti-CTLA-4 Checkpoint Inhibitor-Mediated Anticancer Immunity

The RIG-I Agonist 3pRNA Synergizes with Checkpoint Blockade in Cancer Immunotherapy

Constitutive gp130-JAK-STAT3 Signaling Induces a Plasma Cell Disorder Representing Genetic and Clinical Features of Human Myeloma – a Novel in Vivo Model for the Patient Subgroup Characterized By a STAT3 Target Gene Signature

A Mouse Model for XLP-2 Disease Uncovers a Critical Function for IL-1beta and TNF in Driving Hyper-Inflammation

MCL-1 Critically Regulates Survival Of T-Lymphocyte Non-Hodgkin Lymphoma

Multiple ITAM-coupled NK-cell receptors engage the Bcl10/Malt1 complex via Carma1 for NF-κB and MAPK activation to selectively control cytokine production

Signaling crosstalk in DLBCL

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American Society of Hematology

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American Society of Hematology

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