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Karin Kleigrewe
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Journal Articles

Loss of Microbiota-Derived Metabolites Is Associated with Mucosal-Barrier-Injury Bloodstream Infection in Patients Undergoing Allogeneic Hematopoietic Stem Cell Transplantation

Sophia Göldel, Tingting Zheng, Tina Eismann, Melanie Tiefgraber, Mats Urban, Alix Schwarz, Klaus Neuhaus, Mohsen Pourjam, Ilias Lagkouvardos, Elisabeth Meedt, Karin Kleigrewe, Julia Frank, Michael Neuenhahn, Dirk H Busch, Peter Herhaus, Mareike Verbeek, Wolfgang Herr, Romana Gerner, Klaus-Peter Janssen, Simon M Heidegger, Florian Bassermann, Hendrik Poeck, Melanie Schirmer, Erik Thiele-Orberg
Journal: Blood
Blood (2024) 144 (Supplement 1): 4904.
https://doi.org/10.1182/blood-2024-193273
Published: 2024
Journal Articles

Recovery of the Intestinal Microbiome in Patients at Day +100 after Allogeneic Stem Cell Transplantation Is Defined By Microbial Metabolite Profiles and Linked to Long-Term Outcomes

Alix Schwarz, Tina Eismann, Tingting Zheng, Sophia Goeldel, Mats Urban, Mohsen Pourjam, Klaus Neuhaus, Ilias Lagkouvardos, Daniel Wolff, Peter Herhaus, Mareike Verbeek, Ernst Holler, Wolfgang Herr, Karin Kleigrewe, Simon M Heidegger, Klaus-Peter Janssen, Florian Bassermann, Melanie Schirmer, Hendrik Poeck, Daniela Weber, Erik Thiele Orberg
Journal: Blood
Blood (2024) 144 (Supplement 1): 780.
https://doi.org/10.1182/blood-2024-199035
Published: 2024
Journal Articles

Bacterial and Bacteriophage Consortia Are Associated with Protective Intestinal Immuno-Modulatory Metabolites in Allogeneic Stem Cell Transplantation Patients

Erik Thiele Orberg, Elisabeth Meedt, Andreas Hiergeist, Jinling Xue, Paul Heinrich, Sakhila Ghimire, Oriana Miltiadous, Sarah Lindner, Alix Schwarz, Klaus-Peter Janssen, Peter Herhaus, Mareike Verbeek, Marcel R.M. van den Brink, Daniela Weber, Matthias Edinger, Daniel Wolff, Karin Kleigrewe, Wolfgang Herr, Florian Bassermann, André Gessner, Li Deng, Ernst Holler, Hendrik Poeck
Journal: Blood
Blood (2023) 142 (Supplement 1): 477.
https://doi.org/10.1182/blood-2023-172457
Published: 2023
Journal Articles

Identification of Bacterial and Viral Consortia for the Production of Intestinal Microbiota-Derived Metabolites Associated with Protection in Allogeneic Stem Cell Transplantation Patients

Erik Thiele Orberg, Elisabeth Meedt, Andreas Hiergeist, Jinling Xue, Paul Heinrich, Sakhila Ghimire, Melanie Tiefgraber, Sophia Göldel, Tina Eismann, Alix Schwarz, Sebastian Jarosch, Katja Steiger, Karin Kleigrewe, Julius Clemens Fischer, Klaus-Peter Janssen, Michael Quante, Simon Heidegger, Peter Herhaus, Mareike Verbeek, Jürgen Ruland, Christian Schulz, Daniela Weber, Matthias Edinger, Daniel Wolff, Dirk Busch, Wolfgang Herr, Florian Bassermann, Li Deng, Andre Gessner, Ernst Holler, Hendrik Poeck
Journal: Blood
Blood (2022) 140 (Supplement 1): 7619–7621.
https://doi.org/10.1182/blood-2022-157423
Published: 2022
Journal Articles

Microbial-Derived Metabolites Induce Epithelial Recovery Via the Sting Pathway in Mice and Men and Protect from Graft-Versus-Host Disease

Erik Thiele Orberg, Sascha Göttert, Andreas Hiergeist, Elisabeth Meedt, Karin Kleigrewe, Wolfgang Herr, Florian Bassermann, Andre Gessner, Ernst Holler, Simon Heidegger, Hendrik Poeck
Journal: Blood
Blood (2021) 138 (Supplement 1): 87.
https://doi.org/10.1182/blood-2021-147794
Published: 2021