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Journal Articles

The Carboxy-Terminal Domain of Calreticulin (CALR) Exports the Glucocorticoid Receptor (GR) from the Nucleus to the Cytoplasm of Human Erythroid Cells Resetting Their Stress Response

Anna Rita Migliaccio, PhD, Mario Falchi, PhD, Lilian Varricchio, PhD, Fabrizio Martelli, PhD, Francesca Masiello, MS, Manuela Marra, PhD, Orietta Picconi, Agostino Tafuri, MD, Gabriella Girelli, MD, Carolyn F. Whitsett, MD

Blood (2016) 128 (22): 545.

https://doi.org/10.1182/blood.V128.22.545.545

Published: 2016

Journal Articles

Ribosomal Deficiency Due to Activation of the Thrombopoietin Axis May be Involved in the Reduced Levels of GATA1 Expressed By Megakaryocytes (MKs) from the Gata1 low Model of Myelofibrosis

Anna Rita F Migliaccio, PhD, Maria Zingariello, MD, Laura Sancillo, MS, Fabrizio Martelli, PhD, Fiorella Ciaffoni, PhD, Francesca Masiello, MS, Ilaria Ceglia, PhD, Lilian Varricchio, PhD, Rosa Alba Rana, MD, Changsheng Zhao, PhD, John Crispino, PhD

Blood (2016) 128 (22): 4275.

https://doi.org/10.1182/blood.V128.22.4275.4275

Published: 2016

Journal Articles

Phosphoproteomic Landscaping Unveils Constitutive cKIT Activation in Human Erythroblasts from Polycythemia Vera (PV) Patients

Lilian Varricchio, PhD, Giulia Federici, PhD, Francesca Masiello, MS, Fabrizio Martelli, PhD, Mario Falchi, PhD, Orietta Picconi, Gabriella Girelli, MD, Agostino Tafuri, MD, Emanuel Petricoin III, PhD, Ann Zeuner, PhD, Anna Rita Migliaccio, PhD

Blood (2016) 128 (22): 399.

https://doi.org/10.1182/blood.V128.22.399.399

Published: 2016

Journal Articles

The JAK2 V617F Mutation Disrupts the Regulatory Activity Exerted By Calreticulin on the Glucocorticoid Receptor in Erythroid Cells

Mario Falchi, PhD, Lilian Varricchio, PhD, Fabrizio Martelli, PhD, Francesca Masiello, Orietta Piccioni, Agostino Tafuri, MD, Gabriella Girelli, Camelia Iancu-Rubin, PhD, Ronald Hoffman, MD, Anna Rita Migliaccio, PhD

Blood (2015) 126 (23): 5216.

https://doi.org/10.1182/blood.V126.23.5216.5216

Published: 2015

Journal Articles

2p15-p16.1 microdeletions encompassing and proximal to BCL11A are associated with elevated HbF in addition to neurologic impairment

Alister P. W. Funnell, Paolo Prontera, Valentina Ottaviani, Maria Piccione, Antonino Giambona, Aurelio Maggio, Fiorella Ciaffoni, Sandra Stehling-Sun, Manuela Marra, Francesca Masiello, Lilian Varricchio, John A. Stamatoyannopoulos, Anna R. Migliaccio, Thalia Papayannopoulou

Blood (2015) 126 (1): 89–93.

https://doi.org/10.1182/blood-2015-04-638528

Published: 2015

Includes: Supplemental data

Journal Articles

Identification Of Specific Hematopoietic Populations Present In Peripheral Blood Mononuclear Cells That Increase Erythroid Output Directly Or Through Feeder/Stromal Cell-Like Properties

Esther Heideveld, MS, Valentina Tirelli, MS, Francesca Masiello, Fatemehsadat Esteghamat, Nurcan Yagci, Marieke von Lindern, PhD, Anna Rita F Migliaccio, PhD, Emile van den Akker, PhD

Blood (2013) 122 (21): 3414.

https://doi.org/10.1182/blood.V122.21.3414.3414

Published: 2013

Journal Articles

Differential Modulation Of cKIT Signaling By CD63 Dictates The Magnitude Of Response To Stem Cell Factor Of Erythroblasts From Adult Blood, Cord Blood and Polycythemia Vera

Ann Zeuner, PhD, Giulia Federici, MS, Paola Contavalli, PhD, Emanuel F. Petricoin, PhD, Valentina Tirelli, MS, Francesca Masiello, Gabriella Girelli, MD, Giuliana Alimena, Agostino Tafuri, Giovanni Migliaccio, Ph.D., Anna Rita F Migliaccio, PhD

Blood (2013) 122 (21): 2850.

https://doi.org/10.1182/blood.V122.21.2850.2850

Published: 2013

Journal Articles

The Making Of “Erythroid Islands” In HEMA Culture

Mario Falchi, PhD, Valentina Tirelli, MS, Francesca Masiello, MS, Carolyn Whitsett, Ann Zeuner, PhD, Anna Rita Migliaccio, PhD

Blood (2013) 122 (21): 939.

https://doi.org/10.1182/blood.V122.21.939.939

Published: 2013

Journal Articles

Characterization of the TGF-β1 signaling abnormalities in the Gata1 low mouse model of myelofibrosis

Maria Zingariello, Fabrizio Martelli, Fiorella Ciaffoni, Francesca Masiello, Barbara Ghinassi, Emanuela D’Amore, Margherita Massa, Giovanni Barosi, Laura Sancillo, Xiaochun Li, Judith D. Goldberg, Rosa Alba Rana, Anna Rita Migliaccio

Blood (2013) 121 (17): 3345–3363.

https://doi.org/10.1182/blood-2012-06-439661

Published: 2013

Includes: Supplemental data

Journal Articles

The Glucocorticoid Receptor Plays an Important Role in Controlling Lipid Metabolism During Erythroid Maturation

Valentina Tirelli, MS, Francesca Masiello, MS, Fabrizio Martelli, PhD, Fiorella Ciaffoni, PhD, Giovanni Migliaccio, PhD, Carolyn F. Whitsett, MD, David Ray, MD, Anna Rita F Migliaccio, PhD

Blood (2012) 120 (21): 3195.

https://doi.org/10.1182/blood.V120.21.3195.3195

Published: 2012

Journal Articles

Increased TGF -β 1 expression Cooperates with the Gata1 low Mutation in Determining the Gata1 low Phenotype in CD1 Mice

Fabrizio Martelli, PhD, Fiorella Ciaffoni, PhD, Francesca Masiello, MS, Maria Zingariello, MD, Laura Sancillo, PhD, Rosa Alba Rana, MD, Anna Rita F Migliaccio, PhD

Blood (2012) 120 (21): 3462.

https://doi.org/10.1182/blood.V120.21.3462.3462

Published: 2012

Journal Articles

Different Stress Responses Mediate the Massive Erythroblast Expansion Occurring in Cultures of Human Progenitor Cells Derived From Cord Blood and Adult Blood in the Presence of Glucocorticoid Receptor Agonists.

Giulia Federici, MS, Valentina Tirelli, MS, Francesca Masiello, MS, Lilian Varricchio, PhD, Gabriella Girelli, MD, Ann Zeuner, PhD, Emanuel F. Petricoin, PhD, Anna Rita F Migliaccio, PhD

Blood (2012) 120 (21): 2339.

https://doi.org/10.1182/blood.V120.21.2339.2339

Published: 2012

Journal Articles

Transcriptosome and Phospho-Proteomic Analyses of Erythroblasts Expanded in Vitro From Normal Donors (ND) and From Patients with Polycythemia Vera (PV).

Todd Hricik, BS, Anna Sophia McKenney, MPH, Ross L. Levine, Giulia Federici, MS, Ann Zeuner, PhD, Emanuel F. Petricoin, PhD, Agostino Tafuri, Giuliana Alimena, MD, Valentina Tirelli, MS, Francesca Masiello, MS, Fiorella Ciaffoni, PhD, Anna Rita F Migliaccio, PhD

Blood (2012) 120 (21): 2860.

https://doi.org/10.1182/blood.V120.21.2860.2860

Published: 2012

Journal Articles

Unique Requirements for Lipoproteins Derived From Human Plasma for Maximal Expansion of Human Erythroid Cells Ex-Vivo Under Humanized Conditions

Francesca Masiello, Fiorella Ciaffoni, Valentina Tirelli, Elena Bravo, Anna Rita F Migliaccio, PhD, Giovanni Migliaccio, PhD

Blood (2011) 118 (21): 1257.

https://doi.org/10.1182/blood.V118.21.1257.1257

Published: 2011

Journal Articles

Effects of Ontogeny, Ethnicity, Gender and Loss of Companion Cells on Ex-Vivo Expansion of Erythroid Cells for Transfusion

Valentina Tirelli, Francesca Masiello, Massimo Sanchez, Barbara Ghinassi, Carolyn Whitsett, Giovanni Migliaccio, PhD, Anna Rita F Migliaccio, PhD

Blood (2011) 118 (21): 1261.

https://doi.org/10.1182/blood.V118.21.1261.1261

Published: 2011

Journal Articles

High Levels of CD44 Expression Identify Hematopoietic Cells Capable of Generating Great Numbers of Erythroid Cells Under HEMA Conditions

Anna Rita F Migliaccio, PhD, Valentina Tirelli, Francesca Masiello, Massimo Sanchez, Carolyn Whitsett, Giovanni Migliaccio, PhD

Blood (2010) 116 (21): 3349.

https://doi.org/10.1182/blood.V116.21.3349.3349

Published: 2010

Journal Articles

Mature Erythroblasts Die of Autophagy and Induce Autophagy of Immature Erythroblasts, Limiting the Final Cellular Output In Human Erythroid Massive Amplification (HEMA) Culture

Giovanni Migliaccio, PhD, Francesca Masiello, Valentina Tirelli, Massimo Sanchez, Lilian Varricchio, Carolyn Whitsett, Anna Rita F Migliaccio, PhD

Blood (2010) 116 (21): 339.

https://doi.org/10.1182/blood.V116.21.339.339

Published: 2010

Journal Articles

The Final Cellular Output in Human Erythroid Massive Amplification Culture (HEMA) Is Determined by Dynamic Interactions Between Immature and Mature Cell Populations.

Massimo Sanchez, Ph.D, Francesca Masiello, Ph.D., Valentina Tirelli, Ph.D, Barbara Ghinassi, Carolyn Whitsett, MD, Anna Rita Migliaccio, Ph.D., Giovanni Migliaccio, Ph.D.

Blood (2009) 114 (22): 3156.

https://doi.org/10.1182/blood.V114.22.3156.3156

Published: 2009

Journal Articles

the γ Isoform of the Glucocorticoid Receptor Is Ontogenetically Activated and Predicts Poor Ex-Vivo Expansion of Erythroid Cells From Adult Blood.

Giovanni Migliaccio, Ph.D., Massimo Sanchez, Ph.D, Francesca Masiello, Ph.D., Valentina Tirelli, Ph.D, Lilian Varricchio, Ph.D, Barbara Ghinassi, Ph.D, Carolyn Whitsett, MD, Anna Rita Migliaccio, Ph.D.

Blood (2009) 114 (22): 642.

https://doi.org/10.1182/blood.V114.22.642.642

Published: 2009

Journal Articles

Dynamic Pattern of Adhesion Receptor Expression during the Maturation of Ex-Vivo Generated Human Adult and Neonatal Erythroid Cells.

Giovanni Migliaccio, Ph.D., Massimo Sanchez, Ph.D, Francesca Masiello, Ph.D., Valentina Tirelli, Ph.D, Katija Iliecic, Ph.D., Annalisa Mancini, Ph.D., Paul S. Frenette, MD, Anna Rita Migliaccio, Ph.D.

Blood (2008) 112 (11): 997.

https://doi.org/10.1182/blood.V112.11.997.997

Published: 2008

NARROW

The Carboxy-Terminal Domain of Calreticulin (CALR) Exports the Glucocorticoid Receptor (GR) from the Nucleus to the Cytoplasm of Human Erythroid Cells Resetting Their Stress Response

Ribosomal Deficiency Due to Activation of the Thrombopoietin Axis May be Involved in the Reduced Levels of GATA1 Expressed By Megakaryocytes (MKs) from the Gata1 low Model of Myelofibrosis

Phosphoproteomic Landscaping Unveils Constitutive cKIT Activation in Human Erythroblasts from Polycythemia Vera (PV) Patients

The JAK2 V617F Mutation Disrupts the Regulatory Activity Exerted By Calreticulin on the Glucocorticoid Receptor in Erythroid Cells

2p15-p16.1 microdeletions encompassing and proximal to BCL11A are associated with elevated HbF in addition to neurologic impairment

Identification Of Specific Hematopoietic Populations Present In Peripheral Blood Mononuclear Cells That Increase Erythroid Output Directly Or Through Feeder/Stromal Cell-Like Properties

Differential Modulation Of cKIT Signaling By CD63 Dictates The Magnitude Of Response To Stem Cell Factor Of Erythroblasts From Adult Blood, Cord Blood and Polycythemia Vera

The Making Of “Erythroid Islands” In HEMA Culture

Characterization of the TGF-β1 signaling abnormalities in the Gata1 low mouse model of myelofibrosis

The Glucocorticoid Receptor Plays an Important Role in Controlling Lipid Metabolism During Erythroid Maturation

Increased TGF -β 1 expression Cooperates with the Gata1 low Mutation in Determining the Gata1 low Phenotype in CD1 Mice

Different Stress Responses Mediate the Massive Erythroblast Expansion Occurring in Cultures of Human Progenitor Cells Derived From Cord Blood and Adult Blood in the Presence of Glucocorticoid Receptor Agonists.

Transcriptosome and Phospho-Proteomic Analyses of Erythroblasts Expanded in Vitro From Normal Donors (ND) and From Patients with Polycythemia Vera (PV).

Unique Requirements for Lipoproteins Derived From Human Plasma for Maximal Expansion of Human Erythroid Cells Ex-Vivo Under Humanized Conditions

Effects of Ontogeny, Ethnicity, Gender and Loss of Companion Cells on Ex-Vivo Expansion of Erythroid Cells for Transfusion

High Levels of CD44 Expression Identify Hematopoietic Cells Capable of Generating Great Numbers of Erythroid Cells Under HEMA Conditions

Mature Erythroblasts Die of Autophagy and Induce Autophagy of Immature Erythroblasts, Limiting the Final Cellular Output In Human Erythroid Massive Amplification (HEMA) Culture

The Final Cellular Output in Human Erythroid Massive Amplification Culture (HEMA) Is Determined by Dynamic Interactions Between Immature and Mature Cell Populations.

the γ Isoform of the Glucocorticoid Receptor Is Ontogenetically Activated and Predicts Poor Ex-Vivo Expansion of Erythroid Cells From Adult Blood.

Dynamic Pattern of Adhesion Receptor Expression during the Maturation of Ex-Vivo Generated Human Adult and Neonatal Erythroid Cells.

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American Society of Hematology

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American Society of Hematology

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