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Journal Articles

CD14 + CD16 + Monocyte Binding to Myeloma Cells Is Required for Daratumumab Dependent Killing in Multiple Myeloma Patients

Paola Storti, PhD, Rosanna Vescovini, PhD, Valentina Marchica, MS, Marina Bolzoni, PhD, Federica Costa, MS, Emanuela Vicario, MS, Denise Toscani, PhD, Anna Benedetta Dalla Palma, MD, Fabrizio Accardi, MD, Fabio Malavasi, MD, Franco Aversa, MD, Nicola Giuliani, MD PhD

Blood (2018) 132 (Supplement 1): 3200.

https://doi.org/10.1182/blood-2018-99-112873

Published: 2018

Journal Articles

CD38 antibodies in multiple myeloma: back to the future

Niels W. C. J. van de Donk, Paul G. Richardson, Fabio Malavasi

Blood (2018) 131 (1): 13–29.

https://doi.org/10.1182/blood-2017-06-740944

Published: 2018

Journal Articles

Daratumumab Decreases Treg-Mediated Immunosuppression and Potentiates CD8+ T-Cell-Induced Killing of Chronic Lymphocytic Leukemia (CLL) Cells Ex Vivo

Alak Manna, PhD, Sharoon Akhtar, MPhil, Paul Yi, BS, Sameer A. Parikh, MD, Wei Ding, MD PhD, Jose F. Leis, MD PhD, Victoria R. Alegria, Taimur Sher, MD, Fabio Malavasi, MD, Sikander Ailawadhi, Asher A. Chanan-Khan, MD, Aneel Paulus, MD

Blood (2017) 130 (Supplement 1): 1736.

https://doi.org/10.1182/blood.V130.Suppl_1.1736.1736

Published: 2017

Journal Articles

Daratumumab Mitigates B-Cell Receptor Signaling and Enhances Antitumor Activity of Ibrutinib in Chronic Lymphocytic Leukemia (CLL) Cells

Alak Manna, PhD, Sharoon Akhtar, MPhil, Zahara Meghji, Kirtipal Bhatia, Paul Yi, BS, Sameer A. Parikh, MD, Wei Ding, MD PhD, Jose F. Leis, MD PhD, Taimur Sher, MD, Fabio Malavasi, MD, Victoria R. Alegria, Sikander Ailawadhi, Asher A. Chanan-Khan, MD, Aneel Paulus, MD

Blood (2017) 130 (Supplement 1): 3019.

https://doi.org/10.1182/blood.V130.Suppl_1.3019.3019

Published: 2017

Journal Articles

Targeting CD38 with Daratumumab Suppresses B-Cell Receptor Signaling and Enhances the Activity of Ibrutinib in Waldenstrom Macroglobulinemia Cells

Aneel Paulus, MD, Alak Manna, PhD, Sharoon Akhtar, MPhil, Taimur Sher, MD, Vivek Roy, MD, Morton Coleman, MD, Anne J Novak, PhD, Stephen M Ansell, MD PhD, Fabio Malavasi, MD, Sikander Ailawadhi, Asher A. Chanan-Khan, MD

Blood (2017) 130 (Supplement 1): 1529.

https://doi.org/10.1182/blood.V130.Suppl_1.1529.1529

Published: 2017

Journal Articles

Precision Targeting of Ion Channel Blocker for the Treatment of AML

David Marshall, BS, Antonella Chillemi, PhD, Fabio Malavasi, MD, James Prudent, PhD

Blood (2017) 130 (Supplement 1): 5203.

https://doi.org/10.1182/blood.V130.Suppl_1.5203.5203

Published: 2017

Journal Articles

CD38 and Antibody Therapy: What Can Basic Science Add?

Fabio Malavasi, MD, Antonella Chillemi, PhD, Barbara Castella, PhD, Ilaria Schiavoni, PhD, Danny Incarnato, PhD, Stefania Oliva, MD, Alberto L Horenstein, PhD

Blood (2016) 128 (22): SCI-36.

https://doi.org/10.1182/blood.V128.22.SCI-36.SCI-36

Published: 2016

Journal Articles

Clinical efficacy and management of monoclonal antibodies targeting CD38 and SLAMF7 in multiple myeloma

Niels W. C. J. van de Donk, Philippe Moreau, Torben Plesner, Antonio Palumbo, Francesca Gay, Jacob P. Laubach, Fabio Malavasi, Hervé Avet-Loiseau, Maria-Victoria Mateos, Pieter Sonneveld, Henk M. Lokhorst, Paul G. Richardson

Blood (2016) 127 (6): 681–695.

https://doi.org/10.1182/blood-2015-10-646810

Published: 2016

Journal Articles

Generation and Characterization of Microvesicles after Daratumumab Interaction with Myeloma Cells

Antonella Chillemi, PhD, Valeria Quarona, Andrea Zito, Fabio Morandi, PhD, Danilo Marimpietri, Massimiliano Cuccioloni, PhD, Oldham J Robert, Cragg S Mark, PhD, Marina Bolzoni, PhD, Denise Toscani, PhD, Vito Pistoia, MD, Nicola Giuliani, MD PhD, Alberto L Horenstein, PhD, Kate Sasser, PhD, Fabio Malavasi, MD

Blood (2015) 126 (23): 1849.

https://doi.org/10.1182/blood.V126.23.1849.1849

Published: 2015

Journal Articles

SYK Is Involved in the CD38 Signal Transduction Pathway in Chronic Lymphocytic Leukemia

Marco Benkisser-Petersen, Maike Buchner, Arlette Dörffel, Marcus Dühren von Minden, Kerstin Leberecht, Kathrin Kläsener, Rainer Claus, MD, Ariane Ott, Christine Dierks, Hassan Jumaa, Fabio Malavasi, Michael Reth, Hendrik Veelken, Katja Zirlik, MD

Blood (2015) 126 (23): 2910.

https://doi.org/10.1182/blood.V126.23.2910.2910

Published: 2015

Journal Articles

Expression Profile of CD38 and Related Ectoenzymes in Myeloma Bone Niche: A Rational Basis for the Use of Daratumumab to Inhibit Osteoclast Formation and Activity

Denise Toscani, PhD, Marina Bolzoni, PhD, Federica Costa, Valeria Quarona, Valentina Marchica, Cristina Mancini, MD, Eugenia Martella, MD, Sabrina Bonomini, Paola Storti, PhD, Antonella Chillemi, PhD, Fabrizio Accardi, MD, Benedetta Dalla Palma, MD, Luisa Craviotto, MD, Fabio Malavasi, MD, Franco Aversa, MD, Nicola Giuliani, MD PhD

Blood (2015) 126 (23): 2959.

https://doi.org/10.1182/blood.V126.23.2959.2959

Published: 2015

Journal Articles

Ectoenzymes and Their Products As Communicators in the Human Myeloma Niche

Alberto L. Horenstein, PhD, Valentina Ferri, Marina Bolzoni, Valeria Quarona, Antonella Chillemi, Gianluca Zaccarello, Nicola Giuliani, MD PhD, Fabio Malavasi, MD PhD

Blood (2014) 124 (21): 2064.

https://doi.org/10.1182/blood.V124.21.2064.2064

Published: 2014

Journal Articles

CD73-generated extracellular adenosine in chronic lymphocytic leukemia creates local conditions counteracting drug-induced cell death

Sara Serra, Alberto L. Horenstein, Tiziana Vaisitti, Davide Brusa, Davide Rossi, Luca Laurenti, Giovanni D'Arena, Marta Coscia, Claudio Tripodo, Giorgio Inghirami, Simon C. Robson, Gianluca Gaidano, Fabio Malavasi, Silvia Deaglio

Blood (2011) 118 (23): 6141–6152.

https://doi.org/10.1182/blood-2011-08-374728

Published: 2011

Includes: Supplemental data

Journal Articles

CD73-Generated Extracellular Adenosine Creates Microenvironmental Conditions Favoring Growth and Survival of Chronic Lymphocytic Leukemia Cells

Sara Serra, Alberto Horenstein, Tiziana Vaisitti, Davide Brusa, Davide Rossi, Luca Laurenti, Giovanni D'Arena, Marta Coscia, MD, PhD, Claudio Tripodo, Giorgio Inghirami, Simon Robson, Gianluca Gaidano, Fabio Malavasi, Silvia Deaglio

Blood (2011) 118 (21): 621.

https://doi.org/10.1182/blood.V118.21.621.621

Published: 2011

Journal Articles

CD38 Regulates Homing and Engraftment of CLL Cells,

Tiziana Vaisitti, Sara Serra, Valentina Audrito, Chris Pepper, Davide Rossi, Giovanni D'Arena, Luca Laurenti, Antonella Zucchetto, Ph.D., Valter Gattei, Gianluca Gaidano, Fabio Malavasi, Silvia Deaglio

Blood (2011) 118 (21): 3873.

https://doi.org/10.1182/blood.V118.21.3873.3873

Published: 2011

Journal Articles

CD38 and chronic lymphocytic leukemia: a decade later

Fabio Malavasi, Silvia Deaglio, Rajendra Damle, Giovanna Cutrona, Manlio Ferrarini, Nicholas Chiorazzi

Blood (2011) 118 (13): 3470–3478.

https://doi.org/10.1182/blood-2011-06-275610

Published: 2011

Journal Articles

CD38 Expression Marks CLL Cells with Invasive Properties

Tiziana Vaisitti, Cinzia Bologna, Sara Serra, Giovanni D'Arena, Davide Rossi, Chris Pepper, Gianluca Gaidano, MD, Fabio Malavasi, Silvia Deaglio

Blood (2010) 116 (21): 2422.

https://doi.org/10.1182/blood.V116.21.2422.2422

Published: 2010

Journal Articles

E2A Transcriptionally Regulates CD38 Expression In Chronic Lymphocytic Leukemia

Ifigenia Saborit-Villarroya, Tiziana Vaisitti, Davide Rossi, Giovanni D’Arena, Gianluca Gaidano, Fabio Malavasi, Silvia Deaglio

Blood (2010) 116 (21): 3599.

https://doi.org/10.1182/blood.V116.21.3599.3599

Published: 2010

Journal Articles

Nicotinamide Promotes Apoptosis In Chronic Lymphocytic Leukemia through Activation of the p53/Mir-34a/SIRT1 Tumor Suppressor Network

Valentina Audrito, Tiziana Vaisitti, Sara Serra, Davide Rossi, Daniela Gottardi, Giovanni D’Arena, Gianluca Gaidano, Fabio Malavasi, Silvia Deaglio

Blood (2010) 116 (21): 4627.

https://doi.org/10.1182/blood.V116.21.4627.4627

Published: 2010

Journal Articles

Monocytes/Macrophages Are the Major Targets of the CCL3 Chemokine Produced by CD38 + CD49d + Chronic Lymphocytic Leukemia Cells.

Antonella Zucchetto, Dania Benedetti, Claudio Tripodo, MD, Riccardo Bomben, Fleur Bossi, Michele Dal-Bo, Daniela Marconi, Massimo Degan, Giovanni Del Poeta, Silvia Deaglio, Gianluca Gaidano, MD, Francesco Tedesco, Fabio Malavasi, MD, PhD, Valter Gattei, MD

Blood (2009) 114 (22): 2350.

https://doi.org/10.1182/blood.V114.22.2350.2350

Published: 2009

NARROW

CD14 + CD16 + Monocyte Binding to Myeloma Cells Is Required for Daratumumab Dependent Killing in Multiple Myeloma Patients

CD38 antibodies in multiple myeloma: back to the future

Daratumumab Decreases Treg-Mediated Immunosuppression and Potentiates CD8+ T-Cell-Induced Killing of Chronic Lymphocytic Leukemia (CLL) Cells Ex Vivo

Daratumumab Mitigates B-Cell Receptor Signaling and Enhances Antitumor Activity of Ibrutinib in Chronic Lymphocytic Leukemia (CLL) Cells

Targeting CD38 with Daratumumab Suppresses B-Cell Receptor Signaling and Enhances the Activity of Ibrutinib in Waldenstrom Macroglobulinemia Cells

Precision Targeting of Ion Channel Blocker for the Treatment of AML

CD38 and Antibody Therapy: What Can Basic Science Add?

Clinical efficacy and management of monoclonal antibodies targeting CD38 and SLAMF7 in multiple myeloma

Generation and Characterization of Microvesicles after Daratumumab Interaction with Myeloma Cells

SYK Is Involved in the CD38 Signal Transduction Pathway in Chronic Lymphocytic Leukemia

Expression Profile of CD38 and Related Ectoenzymes in Myeloma Bone Niche: A Rational Basis for the Use of Daratumumab to Inhibit Osteoclast Formation and Activity

Ectoenzymes and Their Products As Communicators in the Human Myeloma Niche

CD73-generated extracellular adenosine in chronic lymphocytic leukemia creates local conditions counteracting drug-induced cell death

CD73-Generated Extracellular Adenosine Creates Microenvironmental Conditions Favoring Growth and Survival of Chronic Lymphocytic Leukemia Cells

CD38 Regulates Homing and Engraftment of CLL Cells,

CD38 and chronic lymphocytic leukemia: a decade later

CD38 Expression Marks CLL Cells with Invasive Properties

E2A Transcriptionally Regulates CD38 Expression In Chronic Lymphocytic Leukemia

Nicotinamide Promotes Apoptosis In Chronic Lymphocytic Leukemia through Activation of the p53/Mir-34a/SIRT1 Tumor Suppressor Network

Monocytes/Macrophages Are the Major Targets of the CCL3 Chemokine Produced by CD38 + CD49d + Chronic Lymphocytic Leukemia Cells.

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American Society of Hematology

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American Society of Hematology

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