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Journal Articles

Role of Nucleophosmin Mutations in AML.

Kotaro Funato, MD, PhD, David W. Sternberg, MD, PhD

Blood (2008) 112 (11): sci-13.

https://doi.org/10.1182/blood.V112.11.sci-13.sci-13

Published: 2008

Journal Articles

Identification of Critical Phosporylation Sites within NPM-ALK That Regulate JUNB mRNA Translation.

Claudia Fuchs, Paul Vesely, Ms, Isabella Bambach, Silvia Schauer, Werner Linkesch, MD, David W. Sternberg, MD, PhD, Gerald Hoefler, MD, Philipp B. Staber, MD

Blood (2007) 110 (11): 3571.

https://doi.org/10.1182/blood.V110.11.3571.3571

Published: 2007

Journal Articles

Translational Regulation of Gene Expression by Cytoplasmic Nucleophosmin in AML: A Global Evaluation of RNA’s Differentially Recruited to Polyribosomes.

Kotaro Funato, MD, PhD, Naznin Haq, Yezhou Sun, PhD, Jin Chen, PhD, Greg Khitrov, PhD, Weijia Zhang, PhD, David W. Sternberg, MD, PhD

Blood (2007) 110 (11): 720.

https://doi.org/10.1182/blood.V110.11.720.720

Published: 2007

Journal Articles

The oncoprotein NPM-ALK of anaplastic large-cell lymphoma induces JUNB transcription via ERK1/2 and JunB translation via mTOR signaling

Philipp B. Staber, Paul Vesely, Naznin Haq, Rene G. Ott, Kotaro Funato, Isabella Bambach, Claudia Fuchs, Silvia Schauer, Werner Linkesch, Andelko Hrzenjak, Wilhelm G. Dirks, Veronika Sexl, Helmut Bergler, Marshall E. Kadin, David W. Sternberg, Lukas Kenner, Gerald Hoefler

Blood (2007) 110 (9): 3374–3383.

https://doi.org/10.1182/blood-2007-02-071258

Published: 2007

Includes: Supplemental data

Journal Articles

NPM-ALK Fusion Tyrosine Kinase of Anaplastic Large Cell Lymphoma Exerts Its Transforming Potential by Increasing Translation of JUNB through mTOR and S6K1.

Philipp B. Staber, MD, Paul Vesely, MS, Rene Ott, PhD, Naznin Haq, Werner Linkesch, MD, Silvia Schauer, Andelko Hrzenjak, PhD, Lukas Kenner, MD, Wilhelm Dirks, PhD, Marshall E. Kadin, MD, David W. Sternberg, MD PhD, Gerald Hoefler, MD

Blood (2006) 108 (11): 1428.

https://doi.org/10.1182/blood.V108.11.1428.1428

Published: 2006

Journal Articles

NPM-ALK Converts JUNB from a Tumor Suppressor to an Oncogene.

Paul Vesely, MS, Philipp B. Staber, MD, Rene Ott, PhD, Montserrat Pinent, PhD, Werner Linkesch, MD, Silvia Schauer, Andelko Hrzenjak, PhD, Marshall E. Kadin, MD, David W. Sternberg, MD PhD, Gerald Hoefler, MD

Blood (2006) 108 (11): 1448.

https://doi.org/10.1182/blood.V108.11.1448.1448

Published: 2006

Journal Articles

Translational Regulation of Gene Expression by the NPM-ALK Fusion Kinase of Anaplastic Large Cell Lymphoma: A Global Evaluation of Differentially Recruited mRNA’s to Polyribosomes.

Kotaro Funato, MD, PhD, Naznin Haq, Yezhou Sun, Jin Chen, Greg Khitrov, PhD, Weijia Zhang, PhD, David W. Sternberg, MD, PhD

Blood (2006) 108 (11): 291.

https://doi.org/10.1182/blood.V108.11.291.291

Published: 2006

Journal Articles

Inhibition of the NPM-ALK Fusion Tyrosine Kinase in Hematopoietic Neoplasia by the Small Molecule Tyrosine Kinase Antagonist TAE684.

David W. Sternberg, MD, PhD, Arghya Ray, PhD, Benjamin H. Lee, MD, PhD, Jennifer Adelsperger, Nicole Duclos, Elizabeth McDowell, Naznin Haq, Patricia Imbach, Osamu Ohmori, Toshiyuki Honda, Markus Warmuth, Doriano Fabbro, PhD, James D. Griffin, MD, Johannes Roesel, PhD

Blood (2006) 108 (11): 828.

https://doi.org/10.1182/blood.V108.11.828.828

Published: 2006

Journal Articles

Lineage Instruction by Oncogenic Tyrosine Kinase Fusions.

Hirokazu Shigematsu, MD, PhD, Shin-ichi Mizuno, MD, Ph.D, Hiromi Iwasaki, MD, Yojiro Arinobu, MD, Ph.D, Hidetoshi Ozawa, PhD, David W. Sternberg, MD, Ph.D, Brian Huntly, MD, Ph.D, D. Gary Gilliland, MD, Ph.D, Koichi Akashi, MD, Ph.D

Blood (2005) 106 (11): 643.

https://doi.org/10.1182/blood.V106.11.643.643

Published: 2005

Journal Articles

Cell Proliferation Induced by the NPM-ALK Fusion Tyrosine Kinase of Anaplastic Large Cell Lymphoma Is Mediated by mTOR/S6K1 and MEK/ERK Signaling.

Ravi K. Amaravadi, MD, Naznin Haq, Stephan W. Morris, MD, D. Gary Gilliland, PhD, MD, David W. Sternberg, MD, PhD

Blood (2004) 104 (11): 241.

https://doi.org/10.1182/blood.V104.11.241.241

Published: 2004

Journal Articles

TEL/PDGFβR Tyrosine Kinase Fusion Specifically Activates Myeloid Differentiation Programs, and Converts Lymphoid Progenitors into the Myeloid Lineage.

Hirokazu Shigematsu, M.D., Ph.D., Hiromi Iwasaki, M.D., Shin-ichi Mizuno, M.D., Ph.D., David W. Sternberg, M.D., Brian J.P. Huntly, M.D., Ph.D., D. Gary Gilliland, M.D., Ph.D., Koichi Akashi, M.D., Ph.D.

Blood (2004) 104 (11): 387.

https://doi.org/10.1182/blood.V104.11.387.387

Published: 2004

Journal Articles

NPM-ALK fusion kinase of anaplastic large-cell lymphoma regulates survival and proliferative signaling through modulation of FOXO3a

Ting-Lei Gu, Zuzana Tothova, Blanca Scheijen, James D. Griffin, D. Gary Gilliland, David W. Sternberg

Blood (2004) 103 (12): 4622–4629.

https://doi.org/10.1182/blood-2003-03-0820

Published: 2004

Journal Articles

The TEL/PDGFβR fusion in chronic myelomonocytic leukemia signals through STAT5-dependent and STAT5-independent pathways

David W. Sternberg, Michael H. Tomasson, Martin Carroll, David P. Curley, George Barker, Michael Caprio, Alyson Wilbanks, Andrius Kazlauskas, D. Gary Gilliland

Blood (2001) 98 (12): 3390–3397.

https://doi.org/10.1182/blood.V98.12.3390

Published: 2001

Journal Articles

H4(D10S170), a gene frequently rearranged in papillary thyroid carcinoma, is fused to the platelet-derived growth factor receptor β gene in atypical chronic myeloid leukemia with t(5;10)(q33;q22)

Juerg Schwaller, Ema Anastasiadou, Danielle Cain, Jeff Kutok, Sarah Wojiski, Ifor R. Williams, Roberta LaStarza, Barbara Crescenzi, David W. Sternberg, Patrick Andreasson, Roberta Schiavo, Salvatore Siena, Cristina Mecucci, D. Gary Gilliland

Blood (2001) 97 (12): 3910–3918.

https://doi.org/10.1182/blood.V97.12.3910

Published: 2001

NARROW

Role of Nucleophosmin Mutations in AML.

Identification of Critical Phosporylation Sites within NPM-ALK That Regulate JUNB mRNA Translation.

Translational Regulation of Gene Expression by Cytoplasmic Nucleophosmin in AML: A Global Evaluation of RNA’s Differentially Recruited to Polyribosomes.

The oncoprotein NPM-ALK of anaplastic large-cell lymphoma induces JUNB transcription via ERK1/2 and JunB translation via mTOR signaling

NPM-ALK Fusion Tyrosine Kinase of Anaplastic Large Cell Lymphoma Exerts Its Transforming Potential by Increasing Translation of JUNB through mTOR and S6K1.

NPM-ALK Converts JUNB from a Tumor Suppressor to an Oncogene.

Translational Regulation of Gene Expression by the NPM-ALK Fusion Kinase of Anaplastic Large Cell Lymphoma: A Global Evaluation of Differentially Recruited mRNA’s to Polyribosomes.

Inhibition of the NPM-ALK Fusion Tyrosine Kinase in Hematopoietic Neoplasia by the Small Molecule Tyrosine Kinase Antagonist TAE684.

Lineage Instruction by Oncogenic Tyrosine Kinase Fusions.

Cell Proliferation Induced by the NPM-ALK Fusion Tyrosine Kinase of Anaplastic Large Cell Lymphoma Is Mediated by mTOR/S6K1 and MEK/ERK Signaling.

TEL/PDGFβR Tyrosine Kinase Fusion Specifically Activates Myeloid Differentiation Programs, and Converts Lymphoid Progenitors into the Myeloid Lineage.

NPM-ALK fusion kinase of anaplastic large-cell lymphoma regulates survival and proliferative signaling through modulation of FOXO3a

The TEL/PDGFβR fusion in chronic myelomonocytic leukemia signals through STAT5-dependent and STAT5-independent pathways

H4(D10S170), a gene frequently rearranged in papillary thyroid carcinoma, is fused to the platelet-derived growth factor receptor β gene in atypical chronic myeloid leukemia with t(5;10)(q33;q22)

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American Society of Hematology

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American Society of Hematology

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