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Journal Articles

Pediatric T-cell lymphoblastic lymphoma but not leukemia harbor TRB::NOTCH1 fusions with unfavorable outcome

Marcel Te Vrugt, Janna Sophie Wessolowski, Gerrit Randau, Amelie Alfert, Stephanie Müller, Kenneth Scholten, Claudia Sopalla, Claudia Lanvers-Kaminsky, Marc Hotfilder, Finn Asmus Lamp, Christine Damm-Welk, Jette Luedersen, Gabriele Escherich, Udo zur Stadt, Lena Behrmann, Wilhelm Woessmann, Ilske Oschlies, Matteo Marzi, Mr., Martin Zimmermann, Birgit Burkhardt
Journal: Blood
Blood blood.2024025307.
https://doi.org/10.1182/blood.2024025307
Published: 2024
Includes: Supplemental data
Journal Articles

Impact of Additional Intensive L-Asparaginase Therapy during Consolidation Phase for High-Risk Acute Lymphoblastic Leukemia: Results of a Randomized Controlled Trial in the AIEOP-BFM ALL 2009 Protocol

Valentino Conter, Maria Grazia Valsecchi, Gunnar Cario, Martin Zimmermann, Andishe Attarbaschi, Jan Stary, Felix Niggli, Luciano Dalla Pozza, Sarah Elitzur, Daniela Silvestri, Franco Locatelli, Anja Moericke, Gernot Engstler, Petr Smisek, Nicole Bodmer, Draga Barbaric, Shai Izraeli, Carmelo Rizzari, Joachim Boos, Barbara Buldini, Claudia Lanvers-Kaminsky, Giovanni Cazzaniga, Bernd Gruhn, Andrea Biondi, Martin Schrappe
Journal: Blood
Blood (2022) 140 (Supplement 1): 109–111.
https://doi.org/10.1182/blood-2022-166583
Published: 2022
Journal Articles

Hypersensitivity Reactions to Native E. coli L-Asparaginase in Children with Acute Lymphoblastic Leukemia May Vary By Treatment Schedule and Type of Glucocorticoid in Induction: Results of Trial ALL-BFM 2000

Anja Möricke, Martin Schrappe, Carmelo Rizzari, Julia Alten, Andishe Attarbaschi, Rita Beier, Andrea Biondi, Birgit Burkhardt, Nicole Bodmer, Joachim Boos, Gunnar Cario, Valentino Conter, Christian Flotho, Andreas E. Kulozik, Claudia Lanvers-Kaminsky, Georg Mann, Felix Niggli, Daniela Silvestri, Arend von Stackelberg, Martin Stanulla, Maria Grazia Valsecchi, Martin Zimmermann
Journal: Blood
Blood (2022) 140 (Supplement 1): 11676–11678.
https://doi.org/10.1182/blood-2022-163142
Published: 2022
Journal Articles

A germ line mutation in cathepsin B points toward a role in asparaginase pharmacokinetics

Clinical Trials & Observations
Laurens T. van der Meer, Esmé Waanders, Marloes Levers, Hanka Venselaar, Debbie Roeleveld, Joachim Boos, Claudia Lanvers, Roger J. Brüggemann, Roland P. Kuiper, Peter M. Hoogerbrugge, Frank N. van Leeuwen, D. Maroeska te Loo
Journal: Blood
Blood (2014) 124 (19): 3027–3029.
https://doi.org/10.1182/blood-2014-06-582627
Published: 2014
Includes: Supplemental data
Journal Articles

A prospective study on drug monitoring of PEGasparaginase and Erwinia asparaginase and asparaginase antibodies in pediatric acute lymphoblastic leukemia

Clinical Trials & Observations
Wing H. Tong, Rob Pieters, Gertjan J. L. Kaspers, D. Maroeska W. M. te Loo, Marc B. Bierings, Cor van den Bos, Wouter J. W. Kollen, Wim C. J. Hop, Claudia Lanvers-Kaminsky, Mary V. Relling, Wim J. E. Tissing, Inge M. van der Sluis
Journal: Blood
Blood (2014) 123 (13): 2026–2033.
https://doi.org/10.1182/blood-2013-10-534347
Published: 2014
Includes: Supplemental data
Journal Articles

A Germline Mutation in Cathepsin B in a Child with ALL Points towards a Key Role for This Enzyme in L-Asparaginase Pharmacokinetics.

Laurens T. van der Meer, PhD, Esmé Waanders, PhD, Marloes Levers, BSc, Hanka Venselaar, MSc, Debbie Roeleveld, BSc, Joachim Boos, MD, PhD, Claudia Lanvers-Kaminsky, PhD, Roland P. Kuiper, PhD, Peter M. Hoogerbrugge, MD, PhD, Frank N. van Leeuwen, PhD, D. Maroeska W.M. te Loo, MD, PhD
Journal: Blood
Blood (2012) 120 (21): 2458.
https://doi.org/10.1182/blood.V120.21.2458.2458
Published: 2012
Journal Articles

Anti– Escherichia coli asparaginase antibody levels determine the activity of second-line treatment with pegylated E coli asparaginase: a retrospective analysis within the ALL-BFM trials

Clinical Trials & Observations
Andrea Willer, Joachim Gerß, Thorsten König, Dieter Franke, Hans-Jürgen Kühnel, Günter Henze, Arendt von Stackelberg, Anja Möricke, Martin Schrappe, Joachim Boos, Claudia Lanvers-Kaminsky
Journal: Blood
Blood (2011) 118 (22): 5774–5782.
https://doi.org/10.1182/blood-2011-07-367904
Published: 2011
Includes: Supplemental data
Journal Articles

The Bone Marrow Niche of Patients with Acute Lymphoblastic Leukemia Produces No Increased Asparagine Levels In Vivo That May Lead to Clinical Asparaginase Resistance

Wing H. Tong, MD, Rob Pieters, MD, PhD, Wim C.J. Hop, PhD, Claudia Lanvers-Kaminsky, PhD, Joachim Boos, MD, PhD, Inge M. van der Sluis, MD, PhD
Journal: Blood
Blood (2011) 118 (21): 1505.
https://doi.org/10.1182/blood.V118.21.1505.1505
Published: 2011
Journal Articles

A Population Pharmacokinetic Model Describing the Activity-Time-Course of PEG-Asparaginase in Children.

Georg Hempel, Claudia Lanvers-Kaminsky, Hans-Joachim Mueller, Gudrun Wuerthwein, Joachim Boos
Journal: Blood
Blood (2004) 104 (11): 2746.
https://doi.org/10.1182/blood.V104.11.2746.2746
Published: 2004
Journal Articles

Pharmacology of PEG-asparaginase in childhood acute lymphoblastic leukemia (ALL)

Joao Paulo Vieira Pinheiro, Claudia Lanvers, Gudrun Würthwein, Joachim Boos
Journal: Blood
Blood (2002) 100 (5): 1923–1925.
https://doi.org/10.1182/blood-2002-04-1282
Published: 2002