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Journal Articles

Multicenter, Open-Label Phase 1/2a Study of Pxs-5505 and Ruxolitinib in Patients with Primary, Post-Polycythemia Vera (PV) or Post-Essential Thrombocythemia (ET) Myelofibrosis

Peter Tan, Ross Baker, Sung-Eun Lee, Anne Marie Watson, Stanley Cheung, Shang-Ju Wu, Chih-Cheng Chen, Shuhying Tan, Pankit Vachhani, Tsai-Yun Chen, Jae Hoon Lee, Hui-Hua Hsiao, Ji Yun Lee, Won Sik Lee, Lucia Masarova, Jana Baskar, Wolfgang Jarolimek, Joanna Leadbetter
Journal: Blood
Blood (2024) 144 (Supplement 1): 1001.
https://doi.org/10.1182/blood-2024-204290
Published: 2024
Journal Articles

Association between JAK2 V617F-Clonal Hematopoiesis of Indeterminate Potential and Microthromboembolism-Related Diseases

Chih-Cheng Chen, Ying-Hsuan Wang, Cih-En Huang, Yi-Yang Chen
Journal: Blood
Blood (2024) 144 (Supplement 1): 5643.
https://doi.org/10.1182/blood-2024-202889
Published: 2024
Journal Articles

Indirect Comparisons of the Efficacy of Epcoritamab Vs Glofitamab in Patients (Pts) with Relapsed or Refractory (R/R) Large B-Cell Lymphoma (LBCL)

John N. Allan, Christopher P Fox, Grzegorz S. Nowakowski, Peter A Riedell, Tycel J. Phillips, Anthony W Wang, Abualbishr Alshreef, Junhua Yu, Cheng Chen, Kavita Sail, Diala Harb, Alex Mutebi, Anindit Chhibber, Brian Elliot, Mohammad Atiya, Catherine Thieblemont
Journal: Blood
Blood (2024) 144 (Supplement 1): 2349.
https://doi.org/10.1182/blood-2024-203994
Published: 2024
Journal Articles

Inequalities in Treatment Utilization Among Older Medicare Beneficiaries with Newly Diagnosed Acute Myeloid Leukemia Who Are Ineligible for Induction Therapy

Amer M. Zeidan, Yanqing Xu, Tatyana A. Kapustyan, Kaylee Miu, Cheng Chen, Rajesh Kamalakar, Chia-Wei Lin, Esprit Ma, Melissa Montez, Zheng Wu, Tracy Yee, Haiyan Sun, Andrew Rava, Sonia Kim, Scott F Huntington
Journal: Blood
Blood (2024) 144 (Supplement 1): 3795.
https://doi.org/10.1182/blood-2024-200213
Published: 2024
Journal Articles

Ropeginterferon Alfa-2b for Pre-Fibrotic Primary Myelofibrosis and DIPSS Low/Intermediate-1 Risk Myelofibrosis: Durable Responses and Evidence of Disease Modification

Harinder Gill, Lester Au, Garret Man Kit Leung, Dorothy Tsai, Rita Yim, Lynn Chin, Vivian Li, Paul Lee, Albert Chun Fung Sin, Hsin An Hou, Chih-Cheng Chen, Yok Lam Kwong
Journal: Blood
Blood (2023) 142 (Supplement 1): 4562.
https://doi.org/10.1182/blood-2023-180922
Published: 2023
Journal Articles

Efficacy and Safety of Ropeginterferon Alfa-2b for Pre-Fibrotic Primary Myelofibrosis and DIPSS Low/Intermediate-1 Risk Myelofibrosis

Harinder Gill, Lester Au, Rita Yim, Lynn Chin, Vivian Li, Paul Lee, Garret MK Leung, Carmen Lee, Tony Kwun Yat Wu, Cheong Ngai, Ryan Ho, Albert Chun Fung Sin, Hsin-An Hou, Chih-Cheng Chen, Yok-Lam Kwong
Journal: Blood
Blood (2022) 140 (Supplement 1): 1522.
https://doi.org/10.1182/blood-2022-169613
Published: 2022
Journal Articles

Leonurine Promotes the Maturation of Healthy Donors and Multiple Myeloma Patients Derived-Dendritic Cells

Cheng Chen, Lin He, Xi Wang, Zichen Ye, Rong Xiao, Hong Zheng, Shu Chen, Hui Li, Xi Yang, Xuemei Wang, Yu Wang, Xuemei Ye, Xiaobing Huang, Jingying Dai
Journal: Blood
Blood (2022) 140 (Supplement 1): 12439.
https://doi.org/10.1182/blood-2022-157665
Published: 2022
Journal Articles

Developing CD70-Targeted CAR-T Cells for the Treatment of Hematological and Solid Malignancies

Yuan Lu, Hui Huang, Cheng Chen, Hui Wang, Huilin Wu, Xiaoqin Liu, Wei Zhao, Chunyan Gao, Siyuan Tan
Journal: Blood
Blood (2022) 140 (Supplement 1): 12695.
https://doi.org/10.1182/blood-2022-160106
Published: 2022
Journal Articles

Treatment of Ropeginterferon Alpha-2b Achieves Hematologic Remission and Molecular Response in Patients with Hydroxyurea- and/or Anagrelide-Resistant/Intolerant Myeloproliferative Neoplasms

Chih-Cheng Chen, Ming-Chung Kuo, Yi-Jiun Su, Cih-En Huang, Chia-Chen Hsu, Yu-Ying Wu, Ying-Ju Chen, Lee-Yung Shih
Journal: Blood
Blood (2021) 138 (Supplement 1): 4631.
https://doi.org/10.1182/blood-2021-147746
Published: 2021
Journal Articles

Changes in the Incidence and Overall Survival of Patients with Myeloproliferative Neoplasms between 2002 and 2016 in the United States

Srdan Verstovsek, MD PhD, Jingbo Yu, MD PhD, Robyn M. Scherber, MD, Shivani Pandya, MS, Christopher Dieyi, MPH, Chien-Cheng Chen, MS, Shreekant Parasuraman, BPharm, PhD
Journal: Blood
Blood (2020) 136 (Supplement 1): 12–13.
https://doi.org/10.1182/blood-2020-141090
Published: 2020
Journal Articles

Developing a Novel Anti-Bcma CAR-T for Relapsed or Refractory Multiple Myeloma

Xin Yao, PhD, Shigui Zhu, PhD, Jiaqi Huang, PhD, Xiaoyan Qu, MD PhD, Judy Zhu, MD, Yutian Wei, MS, Liping Lan, MS, Xiaoteng LV, MS, Junfeng Wu, PhD, Rirfei Wang, MS, Dingzhu Yang, Chengxiao Zheng, MD, DiJun Zhao, MS, Lei Fan, MD PhD, Fei Huang, Hua Lu, MD PhD, Chaocan Zhang, MS, Cheng Chen, PhD, Yanfeng Li, MS, Jiaqiang Ren, MD PhD, Li Zhang, MD, Michael Humphries, MD, Jianyong Li, MD, Yihong Yao, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 50.
https://doi.org/10.1182/blood-2019-125372
Published: 2019
Journal Articles

MMP9 Inhibition Rescues the Erythroid Defect in RPS14-Deficient Del(5q) MDS Models

Minyoung Youn, PhD, Haigen Huang, PhD, Cheng Chen, Sharon Kam, BS, Mark C Wilkes, Hee-Don Chae, PhD, Anupama Narla, MD, Shuo Lin, PhD, Kathleen M. Sakamoto, MD PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 756.
https://doi.org/10.1182/blood-2018-99-117508
Published: 2018
Journal Articles

Antileukemic Activity of 8-Chloro-Adenosine (8-Cl-Ado) Is Mediated By Mir-155 Degradation and ErbB3 Binding Protein (Ebp1)-Dependent p53 Activation: A Novel Therapeutic Approach for FLT3-ITD Acute Myeloid Leukemia (AML)

Ralf Buettner, PhD, Le Xuan Truong Nguyen, PhD, Bijender Kumar, PhD, Corey James Morales, BA, BS, Chao Liu, PhD, Lisa S Chen, PhD, Tea Pemovska, PhD, Ryan Thompson, BS, Ling Li, PhD, Dinh Hoa Hoang, BS, Bin Zhang, PhD, Lucy Ghoda, PhD, Claudia Kowolik, PhD, Mika Kontro, MD, Krister Wennerberg, PhD, Calum Leitch, PhD, Xiaochun Yu, MD PhD, Ching-Cheng Chen, PhD, David Horne, PhD, Varsha Gandhi, PhD, Vinod A. Pullarkat, MD, Guido Marcucci, Steven T Rosen
Journal: Blood
Blood (2018) 132 (Supplement 1): 3938.
https://doi.org/10.1182/blood-2018-99-119880
Published: 2018
Journal Articles

64 cu-DOTA-Anti-CD33 PET-CT Imaging for Acute Myeloid Leukemia and Image-Guided Treatment

Srideshikan Sargur Madabushi, PhD, Darren Zuro, Jamison Brooks, B.S, Bijender Kumar, PhD, Liliana E Parra, Marvin Orellana, B.S, Indu Nair, PhD, Junie Chea, Kofi Poku, PharmD, Ching-Cheng Chen, PhD, James Sanchez, PhD, John E. Shively, Daniel A. Vallera, PhD, Jeffrey Wong, MD, Anthony S. Stein, MD, David Colcher, PhD, Paul Yazaki, PhD, Susanta Hui, PhD, DABR.
Journal: Blood
Blood (2018) 132 (Supplement 1): 2747.
https://doi.org/10.1182/blood-2018-99-117878
Published: 2018
Journal Articles

Single-Cell RNA Sequencing Discloses Distinct Transcriptomic Profiling in Essential Thrombocythemia

Chia-Chen Hsu, PhD, Cih-En Huang, MD, Ying-Ju Chen, Yuying Wu, MD, Hsing-Yi Tsou, Chian-Pei Li, Wei-Hsuan Chuang, Yi-Hua Lai, Yi-Hsuan Lin, Chih-Cheng Chen, MD
Journal: Blood
Blood (2018) 132 (Supplement 1): 3061.
https://doi.org/10.1182/blood-2018-99-113990
Published: 2018
Journal Articles

Leukemia Cells Remodel Adipocyte Niches and Their Progenitor Functions to Generate Leukemia Favoring Niche

Bijender Kumar, PhD, Marvin Orellana, B.S, Jamison Brooks, B.S, Srideshikan Sargur Madabushi, PhD, Liliana E Parra, Darren Zuro, Qiong Wang, Ching-Cheng Chen, PhD, Susanta Hui, PhD, DABR.
Journal: Blood
Blood (2018) 132 (Supplement 1): 1294.
https://doi.org/10.1182/blood-2018-99-115689
Published: 2018
Journal Articles

Comparison of Molecular Responses between e14a2 and e13a2 BCR-ABL1 Transcripts in Patients with Chronic Myeloid Leukemia in Chronic Phase Treated with Front-Line Second Generation Tyrosine Kinase Inhibitors: Taiwan CML Study

Yi-Jiun Su, MD, Ming-Chung Kuo, MD, Chieh-Lin Teng, MD, Tsai-Yun Chen, MD, Ming-Chun Ma, MD, Pei-Ching Hsiao, MD, Ming-Chung Wang, MD, Tung-Huei Lin, MS, Wen-Li Hwang, MD, Chih-Cheng Chen, MD, Youngsen Yang, MD, Sung-Nan Pei, MD, Yen-Min Huang, MD, Sin-Syue Li, MD, Ming-Yang Lee, MD, Hung-I Cheng, MD, Lee-Yung Shih, MD
Journal: Blood
Blood (2017) 130 (Supplement 1): 1603.
https://doi.org/10.1182/blood.V130.Suppl_1.1603.1603
Published: 2017
Journal Articles

8-Chloro-Adenosine Inhibits Molecular Poor-Risk Acute Myeloid Leukemia (AML) and Leukemic Stem Cells (LSC) Growth and Synergizes with the BCL-2 Inhibitor Venetoclax (ABT-199)

Ralf Buettner, PhD, Ching-Cheng Chen, PhD, Bijender Kumar, PhD, Corey Morales, BA, BS, Lisa S Chen, PhD, Krister Wennerberg, PhD, Ryan Thompson, MS, Tea Pemovska, MSc, Ling Li, PhD, Bin Zhang, PhD, Claudia Kowolik, PhD, Mika Kontro, MD, Calum Leitch, MD, David Horne, PhD, Joycelynne Palmer, PhD, Varsha Gandhi, PhD, Guido Marcucci, MD, Vinod Pullarkat, MD, Steven T. Rosen, MD
Journal: Blood
Blood (2016) 128 (22): 2758.
https://doi.org/10.1182/blood.V128.22.2758.2758
Published: 2016
Journal Articles

Aberrant Let7a/HMGA2 Signaling Axis with Unique Clinical Phenotype in JAK2 -Mutated Myeloproliferative Neoplasms

Chia-Chen Hsu, PhD, Chih-Cheng Chen, MD PhD, Jyh-Pyng Gau, MD PhD, Cih-En Huang, MD, Jie-Yu You, MD PhD, Jrhau Lung, PhD, YI-Yang Chen, Hsing-Ying Ho, MS, Chian-Pei Li, MS, Chang-Hsien Lu, MD, Kuan-Der Lee, MD PhD
Journal: Blood
Blood (2016) 128 (22): 5492.
https://doi.org/10.1182/blood.V128.22.5492.5492
Published: 2016
Journal Articles

CBFβ-SMMHC creates aberrant megakaryocyte-erythroid progenitors prone to leukemia initiation in mice

Qi Cai, Robin Jeannet, Wei-Kai Hua, Guerry J. Cook, Bin Zhang, Jing Qi, Hongjun Liu, Ling Li, Ching-Cheng Chen, Guido Marcucci, Ya-Huei Kuo
Journal: Blood
Blood (2016) 128 (11): 1503–1515.
https://doi.org/10.1182/blood-2016-01-693119
Published: 2016
Includes: Supplemental data