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Audrey Nédélec
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Journal Articles

Modulation of human thrombopoietin receptor conformations uncouples JAK2 V617F-driven activation from cytokine-induced stimulation

Nicolas Papadopoulos, Ajda Pristavec, Audrey Nédélec, Gabriel Levy, Judith Staerk, Stefan N. Constantinescu
Journal: Blood
Blood (2023) 142 (21): 1818–1830.
https://doi.org/10.1182/blood.2022019580
Published: 2023
Includes: Supplemental data
Journal Articles

Secreted mutant calreticulins as rogue cytokines in myeloproliferative neoplasms

Christian Pecquet, Nicolas Papadopoulos, Thomas Balligand, Ilyas Chachoua, Amandine Tisserand, Gaëlle Vertenoeil, Audrey Nédélec, Didier Vertommen, Anita Roy, Caroline Marty, Harini Nivarthi, Jean-Philippe Defour, Mira El-Khoury, Eva Hug, Andrea Majoros, Erica Xu, Oleh Zagrijtschuk, Tudor E. Fertig, Daciana S. Marta, Heinz Gisslinger, Bettina Gisslinger, Martin Schalling, Ilaria Casetti, Elisa Rumi, Daniela Pietra, Chiara Cavalloni, Luca Arcaini, Mario Cazzola, Norio Komatsu, Yoshihiko Kihara, Yoshitaka Sunami, Yoko Edahiro, Marito Araki, Roman Lesyk, Veronika Buxhofer-Ausch, Sonja Heibl, Florence Pasquier, Violaine Havelange, Isabelle Plo, William Vainchenker, Robert Kralovics, Stefan N. Constantinescu
Journal: Blood
Blood (2023) 141 (8): 917–929.
https://doi.org/10.1182/blood.2022016846
Published: 2023
Includes: Supplemental data
Journal Articles

Modulation of the Human Thrombopoietin Receptor Conformation Uncouples JAK2 V617F-Driven from Cytokine-Induced Activation

Nicolas Papadopoulos, Ajda Pristavec, Gabriel Levy, Audrey Nédélec, Judith Staerk, Stefan N. Constantinescu
Journal: Blood
Blood (2022) 140 (Supplement 1): 3878–3879.
https://doi.org/10.1182/blood-2022-166405
Published: 2022
Journal Articles

Hematoxylin binds to mutant calreticulin and disrupts its abnormal interaction with thrombopoietin receptor

Ruochen Jia, Thomas Balligand, Vasyl Atamanyuk, Harini Nivarthi, Erica Xu, Leon Kutzner, Jakob Weinzierl, Audrey Nedelec, Stefan Kubicek, Roman Lesyk, Oleh Zagrijtschuk, Stefan N. Constantinescu, Robert Kralovics
Journal: Blood
Blood (2021) 137 (14): 1920–1931.
https://doi.org/10.1182/blood.2020006264
Published: 2021
Includes: Supplemental data