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Journal Articles

Pirtobrutinib vs bendamustine plus rituximab (BR) in patients with CLL/SLL: First results from a randomized phase III study Examining a non-covalent BTK inhibitor in untreated patients

Free
Wojciech Jurczak, Michal Kwiatek, Jaroslaw Czyz, Ederson de Mattos, Ki-Seong Eom, Alexander Egle, Anna Panovská, Zhanet Grudeva-Popova, Hsuan-Jen Shih, Luis Felipe Casado Montero, Paolo Sportoletti, Vu Minh Hua, James D'Olimpio, Shinsuke Iida, Rodrigo Ito, Katherine Bao, Anne Fink, Weiji Su, Amy Ruppert Stark, Alejandro Levy, Tomasz Wrobel
Journal: Blood
Blood (2025) 146 (Supplement 2): LBA-3.
https://doi.org/10.1182/blood-2025-LBA-3
Published: 2025
Journal Articles

Pirtobrutinib vs ibrutinib in treatment-naïve and relapsed/refractory CLL/SLL: Results from the first randomized phase III study comparing a non-covalent and covalent BTK inhibitor

Free
Jennifer Woyach, Lugui Qiu, Sebastian Grosicki, Tomasz Wrobel, Marcelo Capra, Jaroslaw Czyz, Shuhua Yi, Ki-Seong Eom, Anna Panovská, Wojciech Jurczak, Kamel Laribi, Lutz Jacobasch, Ross Baker, Richy Agajanian, Alejandro Berkovits, Muhit Özcan, Stephane Lepretre, Catherine Coombs, Paula Cramer, Katharine Lewis, Marisa Hill, Katherine Bao, Yuanyuan Bian, Amy Ruppert Stark, Ching Ching Leow, William Wierda
Journal: Blood
Blood (2025) 146 (Supplement 1): 683.
https://doi.org/10.1182/blood-2025-683
Published: 2025
Journal Articles

Second Line Treatment with Bruton Tyrosine Kinase Inhibitor (BTKi) or Bcl-2 Inhibitor (Bcl-2i) in Patients with Chronic Lymphocytic Leukemia (CLL): Primary Analysis of the Czech Study Group for CLL (CSCLL)

Free
Jana Mihalyova, Anna Panovska, Martin Simkovic, Peter Turcsanyi, Martin Spacek, Martin Brejcha, Daniel Lysak, Heidi Mocikova, Sarka Pavlova, Marika Chrapava, Jana Zuchnicka, Yvona Brychtova, Pavel Vodarek, Renata Urbanova, Tereza Likarova, Jitka Malcikova, Tereza Jurkova, Klara Lancova, Lucie Bezdekova, Tomas Papajik, Jana Baranova, Tomas Arpas, Sarka Pospisilova, Lukas Smolej, Michael Doubek
Journal: Blood
Blood (2023) 142 (Supplement 1): 6542.
https://doi.org/10.1182/blood-2023-181249
Published: 2023
Journal Articles

Low-burden TP53 mutations in CLL: clinical impact and clonal evolution within the context of different treatment options

Free
Clinical Trials & Observations
Jitka Malcikova, Sarka Pavlova, Barbara Kunt Vonkova, Lenka Radova, Karla Plevova, Jana Kotaskova, Karol Pal, Barbara Dvorackova, Marcela Zenatova, Jakub Hynst, Eva Ondrouskova, Anna Panovska, Yvona Brychtova, Kristyna Zavacka, Boris Tichy, Nikola Tom, Jiri Mayer, Michael Doubek, Sarka Pospisilova
Journal: Blood
Blood (2021) 138 (25): 2670–2685.
https://doi.org/10.1182/blood.2020009530
Published: 2021
Includes: Supplemental data
Journal Articles

Single-Agent Ibrutinib Versus Real-World (RW) Treatments for Patients with Previously Untreated Chronic Lymphocytic Leukemia (CLL): Adjusted Comparison of Resonate-2™ with the Cllear and Lyon-Sud Rw Databases

Free
Michael Doubek, Mudr. Lukas Smolej, Martin Šimkovič, Anna Panovska, Renata Urbanova, Daniel Lysak, Evelyne Callet-Bauchu, Emmanuel Bachy, Lucile Baseggio, Emmanuelle Ferrant, Joris Diels, Jedelyn Cabrieto, Lasse Nielsen, Gilles Salles
Journal: Blood
Blood (2021) 138 (Supplement 1): 4679.
https://doi.org/10.1182/blood-2021-147927
Published: 2021
Journal Articles

FoxO1-GAB1 axis regulates homing capacity and tonic AKT activity in chronic lymphocytic leukemia

Free
Vaclav Seda, Eva Vojackova, Laura Ondrisova, Lenka Kostalova, Sonali Sharma, Tomas Loja, Gabriela Mladonicka Pavlasova, Daniel Zicha, Marie Kudlickova Peskova, Jan Krivanek, Kvetoslava Liskova, Leos Kren, Vladimir Benes, Katerina Musilova Litzmanova, Marek Borsky, Jan Oppelt, Jan Verner, Sarka Pospisilova, Yvona Brychtova, Anna Panovska, Zhi Tan, Shuxing Zhang, Michael Doubek, Katerina Amruz Cerna, Jiri Mayer, Marek Mraz
Journal: Blood
Blood (2021) 138 (9): 758–772.
https://doi.org/10.1182/blood.2020008101
Published: 2021
Includes: Supplemental data
Journal Articles

Ofatumumab Added To Dexamethasone In Patients With Relapsed Or Refractory Chronic Lymphocytic Leukemia. Results From a Phase II Study Of The Czech Leukemia Study Group For Life

Free
Michael Doubek, Yvona Brychtova, MD, PhD, Anna Panovska, MD, Jakub Trizuljak, MD, Ludmila Sebejova, Olga Stehlikova, MSc., Jana Chovancova, DVM, Jitka Malcikova, PhD, Jana Smardova, MD, PhD, Karla Plevova, MSc., Pavlina Volfova, MSc., Martin Trbusek, PhD, Marek Mraz, MD, PhD, Denisa Majercakova, MD, Petra Obrtlikova, MD, Josef Karban, MD, Lukas Smolej, MD, PhD, Michaela Lindtnerova, MD, Alexandra Oltova, MD, Eva Jelinkova, MSc., Sarka Pospisilova, Jiri Mayer, MD, PhD
Journal: Blood
Blood (2013) 122 (21): 2877.
https://doi.org/10.1182/blood.V122.21.2877.2877
Published: 2013
Journal Articles

The Fate of Chronic Lymphocytic Leukemia Patients After Failure of Fludarabine, Cyclophosphamide, and Rituximab Regimen

Free
Anna Panovska, MD, Daniel Lysák, MD, Lukas Smolej, M.D., Ph.D., Yvona Brychtova, M.D., Ph.D., Martin Simkovic, MD, Monika Motyckova, M.D., Michaela Lindtnerova, MD, Martin Trbusek, PhD, Jitka Malcikova, Dr, PhD, Sarka Pospisilova, Prof., Jiri Mayer, M.D., PhD., Prof., Michael Doubek, M.D., PhD., Prof.
Journal: Blood
Blood (2012) 120 (21): 4603.
https://doi.org/10.1182/blood.V120.21.4603.4603
Published: 2012
Journal Articles

Rituximab In Combination with High-Dose Dexamethasone: An Effective Treatment Option for Patients with Relapsed/Refractory Chronic Lymphocytic Leukemia

Free
Michael Doubek, MD, PhD, Martin Simkovic, MD, Anna Panovska, MD, Monika Hrudkova, MD, David Belada, MD, PhD, Yvona Brychtova, MD, Jiri Mayer, MD, PhD, Lukas Smolej, M.D., Ph.D.
Journal: Blood
Blood (2010) 116 (21): 4629.
https://doi.org/10.1182/blood.V116.21.4629.4629
Published: 2010
Journal Articles

Clinical Outcome of B-Cell Chronic Lymphocytic Leukemia Following Alemtuzumab Therapy: Retrospective Study within Various Cytogenetic Risk Categories

Free
Michael Fiegl, Martin Erdel, Inge Tinhofer, Georg Hopfinger, Karin Eigenberger, Florian Falkner, Andreas Falkner, Yvona Brychtova, Anna Panovska, Michael Doubek, August Zabernigg, Sigrun Sodia, Helmut Mühlberger, Christa Fonatsch, Günther Gastl, Jiri Mayer, Richard Greil
Journal: Blood
Blood (2008) 112 (11): 3164.
https://doi.org/10.1182/blood.V112.11.3164.3164
Published: 2008