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Lukas Smolej
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Journal Articles

Survival Outcomes of Patients with Relapsed/Refractory Chronic Lymphocytic Leukemia (CLL) Treated in the Chemoimmunotherapy Vs BTK Inhibitor (BTKi) Eras: A European Research Initiative on CLL (ERIC) Study

T C, Eva Minga, Georgios Karakatsoulis, Elisa Albi, Miguel Alcoceba, David Allsup, Francesca Bacchiarri, Sotiria Besikli-Dimou, Sofia Chatzileontiadou, Rosa Collado, Zadie Davis, Maria Dimou, David Donaldson, Maria Efstathopoulou, Sara Galimberti, Andrea Galitzia, Eva Gimeno, Valerio Guarente, Eleftheria Hatzimichael, Jose-Angel Hernandez-Rivas, Gloria Iacoboni, Iliana Konstantinou, Ioannis Kotsianidis, Jana Kotaskova, Andreas Epameinondas Koumpis, Zuzana Kubova, Jorge Labrador, Luca Laurenti, Juan Marquet, Stanislava Maslejova, Carlota Mayor-Bastida, Fatima Miras, Riccardo Moia, Almudena Navarro-Bailon, Jacopo Olivieri, Maria Papaioannou, Anna Puiggros, Gian Matteo Rigolin, Mattia Schipani, Tereza Shokralla, Martin Simkovic, Antigoni Tranidou, Theodoros Vassilakopoulos, Andrea Visentin, Candida Vitale, George Vrachiolias, Renata Walewska, Lucrecia Yanez San Segundo, Jana Zuchnicka, David Graham Oscier, Alessandro Gozzetti, Panayiotis Panayiotidis, Francesc Bosch, Paolo Sportoletti, Blanca Espinet, Gerassimos Pangalis, Maria Angelopoulou, Tomas Papajik, Roberta Murru, Marta Coscia, Antonio Cuneo, Gianluca Gaidano, Niki Stavrogianni, Livio Trentin, Lukas Smolej, Mark Caterwood, Martin Spacek, Sarka Pospisilova, Michael Doubek, Anastasia Chatzidimitriou, Kostas Stamatopoulos, Paolo Ghia, Lydia Scarfo
Journal: Blood
Blood (2024) 144 (Supplement 1): 4619.
https://doi.org/10.1182/blood-2024-202046
Published: 2024
Journal Articles

Second Line Treatment with Bruton Tyrosine Kinase Inhibitor (BTKi) or Bcl-2 Inhibitor (Bcl-2i) in Patients with Chronic Lymphocytic Leukemia (CLL): Primary Analysis of the Czech Study Group for CLL (CSCLL)

Jana Mihalyova, Anna Panovska, Martin Simkovic, Peter Turcsanyi, Martin Spacek, Martin Brejcha, Daniel Lysak, Heidi Mocikova, Sarka Pavlova, Marika Chrapava, Jana Zuchnicka, Yvona Brychtova, Pavel Vodarek, Renata Urbanova, Tereza Likarova, Jitka Malcikova, Tereza Jurkova, Klara Lancova, Lucie Bezdekova, Tomas Papajik, Jana Baranova, Tomas Arpas, Sarka Pospisilova, Lukas Smolej, Michael Doubek
Journal: Blood
Blood (2023) 142 (Supplement 1): 6542.
https://doi.org/10.1182/blood-2023-181249
Published: 2023
Journal Articles

Real-World Evidence on Therapeutic Strategies and Treatment-Sequencing in Patients with Chronic Lymphocytic Leukemia: An International Study of Eric, the European Research Initiative on CLL

Thomas Chatzikonstantinou, Lydia Scarfo, Christos Demosthenous, Jana Kotaskova, Gloria Iacoboni, Evangelia Minga, Dimitra Chammou, Georgios Karakatsoulis, Elisa Albi, Miguel Alcoceba, Shaimaa El-Ashwah, Francesca Bacchiarri, Mehreen Ali Khan, Thérèse Aurran, Anne Calleja, Ramona Cassin, Sofia Chatzileontiadou, Amy Christian, Rainer Claus, Rosa Collado, Marcos Daniel De Deus Santos, Zadie Davis, Maria Dimou, David Donaldson, Gimena Dos Santos, Barbara Dreta, Maria Efstathopoulou, Alicia Enrico, Alberto Fresa, Sara Galimberti, Rocío García-Serra, Isabel González-Gascón Y Marín, Alessandro Gozzetti, Valerio Guarente, Sean Harrop, Eleftheria Hatzimichael, Yair Herishanu, Luca Inchiappa, Michalis Iskas, Ozren Jaksic, Susanne R. Janssen, Elzbieta Kalicinska, Volkan Karakus, Arnon P. Kater, Bonnie Kho, Iliana Konstantinou, Thomas Longval, Maya Koren-Michowitz, Ioannis Kotsianidis, Robert J. Kreitman, Uttam Kumar Nath, Jorge Labrador, Deepesh Lad, Kamel Laribi, Ilana Levy, Alberto Lopez-Garcia, Juan Marquet Palomanes, Stanislava Maslejova, Carlota Mayor-Bastida, Fatiha Merabet, Biljana Mihaljevic, Ivana Milosevic, Fatima Miras, Riccardo Moia, Marta Morawska, Almudena Navarro-Bailón, David Oscier, Jacopo Olivieri, Tomáš Papajík, Maria Papaioannou, Cheyenne Pierie, Anna Puiggros, Gianluigi Reda, Gian Matteo Rigolin, Rosa Ruchlemer, Luana Schiattone, Omur Gokmen Sevindik, Yandong Shen, Martin Šimkovič, Svetlana Smirnova, Dina Sameh Soliman, Martin Špaček, Annett Schiwitza, Tamar Tadmor, Liat Tourjeman, Eric Tse, Andrea Visentin, Kristina Tomic, Michel Van Gelder, Theodoros P. Vassilakopoulos, Candida Vitale, George Vrachiolias, Vojin Vukovic, Zhenshu Xu, Lucrecia Yáñez, Munci Yagci, Mohamed A Yassin, Jana Zuchnicka, Maria K. Angelopoulou, Darko Antic, Bella V. Biderman, Mark Catherwood, Marta Coscia, Antonio Cuneo, Fatih Demirkan, Blanca Espinet, Gianluca Gaidano, Romain Guièze, Olga Kalashnikova, Luca Laurenti, Stephen Mulligan, Roberta Murru, Eugene A. Nikitin, Panayiotis Panayiotidis, Gerasimos Pangalis, Irina Panovska, Viola Maria Popov, Šárka Pospíšilová, Lukas Smolej, Paolo Sportoletti, Niki Stavroyianni, Constantine S. Tam, Livio Trentin, Marek Trněný, Francesc Bosch Albareda, Michael Doubek, Anastasia Chatzidimitriou, Paolo Ghia, Kostas Stamatopoulos
Journal: Blood
Blood (2021) 138 (Supplement 1): 2635.
https://doi.org/10.1182/blood-2021-148738
Published: 2021
Journal Articles

Single-Agent Ibrutinib Versus Real-World (RW) Treatments for Patients with Previously Untreated Chronic Lymphocytic Leukemia (CLL): Adjusted Comparison of Resonate-2™ with the Cllear and Lyon-Sud Rw Databases

Michael Doubek, Mudr. Lukas Smolej, Martin Šimkovič, Anna Panovska, Renata Urbanova, Daniel Lysak, Evelyne Callet-Bauchu, Emmanuel Bachy, Lucile Baseggio, Emmanuelle Ferrant, Joris Diels, Jedelyn Cabrieto, Lasse Nielsen, Gilles Salles
Journal: Blood
Blood (2021) 138 (Supplement 1): 4679.
https://doi.org/10.1182/blood-2021-147927
Published: 2021
Journal Articles

On the road to optimized BTK inhibition in CLL

Clinical Trials & Observations
Lukáš Smolej
Journal: Blood
Blood (2021) 137 (24): 3313–3314.
https://doi.org/10.1182/blood.2021011462
Published: 2021
Journal Articles

Impact of Comorbidities and Concomitant Medications on Survival of Patients with Chronic Lymphocytic Leukemia: Analysis of an Unselected Patient Population from East Bohemia

Pavel Vodarek, MD, Denisa Zeberova, Martin Simkovic, MD PhD, Monika Motyckova, MD PhD, David Belada, MD PhD, Pavel Žák, MD PhD, Lukas Smolej, MD PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 5328.
https://doi.org/10.1182/blood.V130.Suppl_1.5328.5328
Published: 2017
Journal Articles

Single-Agent Ibrutinib Versus Real-World Treatments for Patients with Treatment-Naïve Chronic Lymphocytic Leukemia: Adjusted Comparison of Resonate-2™ with Real-World Databases

Gilles Salles, MD PhD, Lukas Smolej, MD PhD, Emmanuel Bachy, Lucile Baseggio, MD, Hervé Besson, Ruben Hermans, Nollaig Healy, Jamie Garside, Wafae Iraqi, Joris Diels, Finlay MacDougall, Corinna Pick-Lauer, Martin Spacek, Renata Urbanova, Daniel Lysak, Evelyne Callet-Bauchu, Michael Doubek, MD PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 5342.
https://doi.org/10.1182/blood.V130.Suppl_1.5342.5342
Published: 2017
Journal Articles

Outcome of Patients with Hodgkin Lymphoma transformed from Chronic Lymphocytic Leukemia

Heidi Mocikova, MD, PhD, Jana Markova, MD, Lubica Gaherova, MD, Lukas Smolej, MD, PhD, Assoc.Prof., Martin Simkovic, MD, Tomas Kozak, MD, PhD, Prof.
Journal: Blood
Blood (2015) 126 (23): 5298.
https://doi.org/10.1182/blood.V126.23.5298.5298
Published: 2015
Journal Articles

Rituximab Maintenance after Chemoimmunotherapy Induction in 1 st and 2 nd Line Improves Progression Free Survival: Planned Interim Analysis of the International Randomized AGMT-CLL8/a Mabtenance Trial

Richard Greil, MD, Petra Obrtlikova, MD PhD, Lukas Smolej, MD PhD, Tomas Kozak, MDPhD, Michael Steurer, MD, Johannes Andel, MD, Josef Thaler, MD, Eva Mikuskova, MD, Liana Gercheva, MD, Thomas Nösslinger, MD, Miriam Ladicka, MD, Michael Girschikofsky, MD, MikulᚠHrubiško, MD PhD, Prof., Ulrich Jäger, MD, Michael A. Fridrik, MD, Martin Pecherstorfer, MD, Eva Kralikova, MD, Cristina Burcoveanu, MD, Stefcho Goranov, MD, Jana Jurkovikova, MD, Andreas L. Petzer, MD, Georgi G. Mihaylov, MD PhD, Julian Raynov, MD, Horst Oexle, MD, August Zabernigg, MD, Emilia Flochova, MD PhD, Stanislav Palasthy, MD, Thomas Melchardt, MD, Jiri Mayer, MD, Alexander Egle, MD
Journal: Blood
Blood (2014) 124 (21): 20.
https://doi.org/10.1182/blood.V124.21.20.20
Published: 2014
Journal Articles

Ofatumumab (OFA) Maintenance Prolongs PFS in Relapsed CLL: Prolong Study Interim Analysis Results

Marinus H.J. van Oers, Kazimierz Kuliczkowski, MD PhD Prof., Lukas Smolej, Mario Petrini, Fritz Offner, Sebastian Gorsicki, Mark-David Levin, Ira Gupta, Jennifer Phillips, Vanessa Williams, Steen Lisby, Christian Geisler
Journal: Blood
Blood (2014) 124 (21): 21.
https://doi.org/10.1182/blood.V124.21.21.21
Published: 2014
Journal Articles

Low-Dose FCR Is a Safe and Effective Treatment Option for Elderly/Comorbid Patients with Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma. Updated Results of Project Q-Lite By Czech CLL Study Group

Lukas Smolej, MDPhD, Yvona Brychtova, MD PhD, Michael Doubek, Prof., MD PhD, Eduard Cmunt, MDPhD, Martin Spacek, MD, PhD, David Belada, MD, Monika Motyckova, MDPhD, Irena Zygulova, MD, Dagmar Adamova, MD, Vit Prochazka, MDPhD, Martin Simkovic, MD, Katerina Klaskova, MS, Tomas Kozak, MDPhD
Journal: Blood
Blood (2014) 124 (21): 4670.
https://doi.org/10.1182/blood.V124.21.4670.4670
Published: 2014
Journal Articles

Ofatumumab Added To Dexamethasone In Patients With Relapsed Or Refractory Chronic Lymphocytic Leukemia. Results From a Phase II Study Of The Czech Leukemia Study Group For Life

Michael Doubek, Yvona Brychtova, MD, PhD, Anna Panovska, MD, Jakub Trizuljak, MD, Ludmila Sebejova, Olga Stehlikova, MSc., Jana Chovancova, DVM, Jitka Malcikova, PhD, Jana Smardova, MD, PhD, Karla Plevova, MSc., Pavlina Volfova, MSc., Martin Trbusek, PhD, Marek Mraz, MD, PhD, Denisa Majercakova, MD, Petra Obrtlikova, MD, Josef Karban, MD, Lukas Smolej, MD, PhD, Michaela Lindtnerova, MD, Alexandra Oltova, MD, Eva Jelinkova, MSc., Sarka Pospisilova, Jiri Mayer, MD, PhD
Journal: Blood
Blood (2013) 122 (21): 2877.
https://doi.org/10.1182/blood.V122.21.2877.2877
Published: 2013
Journal Articles

Rituximab and High-Dose Dexamethasone (R-dex) Is Effective In The Treatment Of Relapsed/Refractory Chronic Lymphocytic Leukemia

Martin Simkovic, M.D., David Belada, M.D., Ph.D., Monika Motyckova, M.D., Lukas Smolej, MD, PhD, Pavel Zak, Assoc. Prof., MD, PhD
Journal: Blood
Blood (2013) 122 (21): 4184.
https://doi.org/10.1182/blood.V122.21.4184.4184
Published: 2013
Journal Articles

A Multicenter, Phase IV Observational Study Of Ofatumumab In Chronic Lymphocytic Leukemia (CLL): A European Research Initiative On CLL (ERIC) Study

Carol Moreno, MD, Marco Montillo, MD, Panayiotidis Panayiotis, MD, Adrian Bloor, PhD, FRCP, FRCPath, Jehan Dupuis, MD, Anna Schuh, MD, PhD, Stefan Norin, MD, Christian H Geisler, Peter Hillmen, MB ChB, PhD, Michael Doubek, Prof., Petra Obrtlikova, MD, Luca Laurenti, MD, Stephan Stilgenbauer, MD, Lukas Smolej, MD, PhD, Paolo Ghia, MD, PhD, Florence Cymbalista, MD, PhD, Ulrich Jaeger, Niki Stavroyianni, Patrick Carrington, MD, Hamadi Zouabi, MD, Veronique Leblond, MD, Juan Carlos Gomez, MD, Roberto Marasca, MD, Gerardo Musuraca, MD, PHD, Luigi Rigacci, MD, Lucia Farina, Rossella Paolini, Sarka Pospisilova, Prof., Eva Kimby, MD, Colm Bradley, Emili Montserrat, MD, PhD
Journal: Blood
Blood (2013) 122 (21): 1645.
https://doi.org/10.1182/blood.V122.21.1645.1645
Published: 2013
Journal Articles

The Fate of Chronic Lymphocytic Leukemia Patients After Failure of Fludarabine, Cyclophosphamide, and Rituximab Regimen

Anna Panovska, MD, Daniel Lysák, MD, Lukas Smolej, M.D., Ph.D., Yvona Brychtova, M.D., Ph.D., Martin Simkovic, MD, Monika Motyckova, M.D., Michaela Lindtnerova, MD, Martin Trbusek, PhD, Jitka Malcikova, Dr, PhD, Sarka Pospisilova, Prof., Jiri Mayer, M.D., PhD., Prof., Michael Doubek, M.D., PhD., Prof.
Journal: Blood
Blood (2012) 120 (21): 4603.
https://doi.org/10.1182/blood.V120.21.4603.4603
Published: 2012
Journal Articles

Correlations Between Ofatumumab Exposure and Treatment Outcomes for Patients with Chronic Lymphocytic Leukemia (CLL) Treated with Frontline Ofatumumab, Fludarabine, and Cyclophosphamide Chemoimmunotherapy

William G. Wierda, MD, PhD, Roxanne C. Jewell, PhD, Thomas J. Kipps, M.D., Ph.D, Jan Dürig, MD, Laimonas Griskevicius, Stephan Stilgenbauer, MD, Lukas Smolej, M.D., Ph.D., Georg Hess, Francisco J. Hernandez-Ilizaliturri, MD, Swaminathan Padmanabhan, MBBS, MD, Lei Fang, Michele M. Gorczyca, MS, Geoffrey W. Chan, MD, Ira V. Gupta, MD, Steen Lisby
Journal: Blood
Blood (2011) 118 (21): 1793.
https://doi.org/10.1182/blood.V118.21.1793.1793
Published: 2011
Journal Articles

Five-Color Multiplex Real-Time PCR Technology to Detect Over 75 Recurrent Chromosomal Abnormalities in Acute Myeloid Leukemia; Benefits for Minimal Residual Disease Detection

Radek Plachy, Lenka Zejskova, Radek Cmejla, PhD, David Warren Hardekopf, Tereza Jancuskova, Lucie Krutilkova, Michal Karas, Vladimir Koza, MD, Jan Vydra, Pavel Zak, MD, PhD, Lukas Smolej, M.D., Ph.D., Sona Pekova
Journal: Blood
Blood (2011) 118 (21): 2526.
https://doi.org/10.1182/blood.V118.21.2526.2526
Published: 2011
Journal Articles

The Detection of Viral Infection in Bronchoalveolar Lavage Samples Collected From Recipients of Allogeneic Haematological Stem Cell Transplantation with Pneumonia (A 3 Year Epidemiological Study 2008–2010)

Eva Stepanova, Jr., MD, Pavel Zak, MD, PhD, Alzbeta Zavrelova, MD, Melanie Cermanova, MD, PHD, Jakub Radocha, MD, Lenka Pliskova, Sr., MD, Vlasta Stepanova, MD, Lukas Smolej, M.D., Ph.D.
Journal: Blood
Blood (2011) 118 (21): 4577.
https://doi.org/10.1182/blood.V118.21.4577.4577
Published: 2011
Journal Articles

Identification of Novel Molecular Markers for the Follow-up of Minimal Residual Disease in Hematooncological Disorders

David Warren Hardekopf, Tereza Jancuskova, Marie Jarosova, Lucie Krutilkova, Radek Plachy, Lenka Zejskova, Radek Cmejla, PhD, Jan Vydra, Tomas Kozak, MD, PhD, Michal Karas, Vladimir Koza, MD, Alzbeta Zavrelova, MD, Pavel Zak, MD, PhD, Lukas Smolej, M.D., Ph.D., Sona Pekova
Journal: Blood
Blood (2011) 118 (21): 4905.
https://doi.org/10.1182/blood.V118.21.4905.4905
Published: 2011
Journal Articles

Chemoimmunotherapy with O-FC in previously untreated patients with chronic lymphocytic leukemia

Clinical Trials & Observations
William G. Wierda, Thomas J. Kipps, Jan Dürig, Laimonas Griskevicius, Stephan Stilgenbauer, Jiří Mayer, Lukáš Smolej, Georg Hess, Rasa Griniute, Francisco J. Hernandez-Ilizaliturri, Swaminathan Padmanabhan, Michele Gorczyca, Chai-Ni Chang, Geoffrey Chan, Ira Gupta, Tina G. Nielsen, Charlotte A. Russell
Journal: Blood
Blood (2011) 117 (24): 6450–6458.
https://doi.org/10.1182/blood-2010-12-323980
Published: 2011
Includes: Supplemental data