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Journal Articles

Glucagon-like Peptide 1 Receptor Agonists Reduce the Risk of Venous Thromboembolism in Patients with Diabetes Irrespective of Obesity: A Propensity Score-Matched Multicenter Database Analysis

Cho Han Chiang, Soravis Osataphan, Yu-Cheng Chang, Yu-Che Lee, Ko-Yun Chang, Cho-Hung Chiang, Mandy N. Lauw, Kenneth A Bauer, Dhruv S. Kazi, Rushad Patell
Journal: Blood
Blood (2024) 144 (Supplement 1): 701.
https://doi.org/10.1182/blood-2024-206409
Published: 2024
Journal Articles

Leveraging Population-Scale Multiomic Datasets to Elucidate the Risk of Thrombosis Associated with Protein S ( PROS1 ) Deficiency

Sharjeel A Chaudhry, Amelia K Haj, Justine Ryu, Sean J. Jurgens, Alfonso Rodriguez Espada, Xin Wang, Seung Hoan Choi, Simone Sanna-Cherchi, Kenneth A Bauer, Patrick Ellinor, Pavan K Bendapudi
Journal: Blood
Blood (2024) 144 (Supplement 1): 17.
https://doi.org/10.1182/blood-2024-205805
Published: 2024
Journal Articles

Use of Large-Scale Genomic Datasets to Identify Additional Modifiers of Thrombosis Risk Among 26,436 Carriers of the Factor V Leiden and Prothrombin G20210A Mutations

Justine Ryu, Sean J. Jurgens, Satoshi Koyama, Leo Wijdeveld, Joel Rämö, Amelia K Haj, Xin Wang, Marisa Brake, Alfred I Lee, Kenneth A Bauer, Patrick Ellinor, Pavan K Bendapudi
Journal: Blood
Blood (2024) 144 (Supplement 1): 18.
https://doi.org/10.1182/blood-2024-207841
Published: 2024
Journal Articles

Thrombosis risk in single- and double-heterozygous carriers of factor V Leiden and prothrombin G20210A in FinnGen and the UK Biobank

Clinical Trials & Observations
Justine Ryu, Joel T. Rämö, Sean J. Jurgens, Teemu Niiranen, Simone Sanna-Cherchi, Kenneth A. Bauer, Amelia Haj, Seung Hoan Choi, Aarno Palotie, Mark Daly, Patrick T. Ellinor, Pavan K. Bendapudi
Journal: Blood
Blood (2024) 143 (23): 2425–2432.
https://doi.org/10.1182/blood.2023023326
Published: 2024
Includes: Supplemental data
Journal Articles

Meta-Analysis of National-Level Genotyping Datasets to Determine the Risk of Thrombosis in Double Heterozygous Carriers of Factor V Leiden and the Prothrombin G20210A Mutation across 876,417 Individuals

Justine Ryu, Joel Rämö, Sean J. Jurgens, Teemu Niiranen, Aarno Palotie, Mark Daly, Simone Sanna-Cherchi, Patrick Ellinor, Kenneth A Bauer, Pavan K Bendapudi
Journal: Blood
Blood (2023) 142 (Supplement 1): 806.
https://doi.org/10.1182/blood-2023-187105
Published: 2023
Journal Articles

Hispanic or Latin American Ancestry Is Associated with a Similar Genomic Profile and a Trend Toward Inferior Outcomes in Newly Diagnosed Multiple Myeloma As Compared to Non-Hispanic White Patients in the Multiple Myeloma Research Foundation (MMRF) CoMMpassstudy

Louis Williams, Patrick Blaney, Eileen M Boyle, Hussein Ghamlouch, Yubao Wang, Jinyoung Choi, Michael A Bauer, Ariel Siegel, James Stoeckle, Beatrice Razzo, Daniel Auclair, David Kaminetzky, Marc Braunstein, Benedetto Bruno, Arnaldo A. Arbini, Brian A Walker, Faith E. Davies, Gareth J Morgan
Journal: Blood
Blood (2021) 138 (Supplement 1): 4117.
https://doi.org/10.1182/blood-2021-148854
Published: 2021
Journal Articles

Multiomic Mapping of Copy Number and Structural Variation on Chromosome 1 (Chr1) Highlights Multiple Recurrent Disease Drivers

Patrick Blaney, Eileen M Boyle, Yubao Wang, Hussein Ghamlouch, Jinyoung Choi, Louis Williams, Stoeckle James, Ariel Siegel, Beatrice Razzo, Marc Braunstein, David Kaminetzky, Arnaldo A Arbini, Benedetto Bruno, Jill Corre, Lydia Montes, Daniel Auclair, Faith E. Davies, Aristotelis Tsirigos, Even H Rustad, Francesco Maura, Ola Landgren, Michael A Bauer, Brian Walker, Gareth Morgan
Journal: Blood
Blood (2021) 138 (Supplement 1): 721.
https://doi.org/10.1182/blood-2021-148439
Published: 2021
Journal Articles

Influence of Aging Processes on the Biology and Outcome of Multiple Myeloma

Eileen M Boyle, MDMSc, Louis Williams, MD MBA, Patrick Blaney, Cody Ashby, PhD, Michael A Bauer, PhD, Brian A Walker, PhD, Jinyoung Choi, PhD, Jessica Caro, MD, Beatrice Razzo, MD, Arnaldo A. Arbini, MD, David Kaminetzky, MD, Marc Braunstein, MDPhD, Francesco Maura, MD, Yubao Wang, PhD, Ola Landgren, MD PhD, James Stoeckle, MD, Kylee H Maclachlan, MBChB, PhD, Rachel Litke, Faith E. Davies, Gareth Morgan, MD PhD
Journal: Blood
Blood (2020) 136 (Supplement 1): 8–9.
https://doi.org/10.1182/blood-2020-138787
Published: 2020
Journal Articles

OrthoCARs: Engineered human IL-2/IL-2Rb orthogonal pairs selectively enhance CAR T cell antitumorefficacy

Paul-Joseph Aspuria, Michael A Bauer, PhD, Sandro vivona, Rene de Waal Malefyt, Rob Kastelein, Martin Oft, Jan Emmerich, Deepti Rokkam, Steven E Kauder, PhD, Scott McCauley, Romina Riener, Rakesh Verma, PhD
Journal: Blood
Blood (2020) 136 (Supplement 1): 35.
https://doi.org/10.1182/blood-2020-143483
Published: 2020
Journal Articles

Postdischarge thrombosis and hemorrhage in patients with COVID-19

Clinical Trials & Observations Brief Report
Rushad Patell, Thomas Bogue, Anita Koshy, Poorva Bindal, Mwanasha Merrill, William C. Aird, Kenneth A. Bauer, Jeffrey I. Zwicker
Journal: Blood
Blood (2020) 136 (11): 1342–1346.
https://doi.org/10.1182/blood.2020007938
Published: 2020
Includes: Supplemental data
Journal Articles

Managing thromboembolic risk in patients with hereditary and acquired thrombophilias

Clinical Trials & Observations
Jason Moran, Kenneth A. Bauer
Journal: Blood
Blood (2020) 135 (5): 344–350.
https://doi.org/10.1182/blood.2019000917
Published: 2020
Journal Articles

The Spectrum of Exomic Mutation in Elderly Myeloma Differs Substantially from Patients at Younger Ages Consistent with a Different Evolutionary Trajectory to Full Blown Disease Based on Age of Onset

Louis Williams, MD MBA, Eileen M Boyle, MD MSc, Faith E. Davies, MD, Brian A Walker, PhD, Cody Ashby, PhD, Michael A Bauer, PhD, Christopher P. Wardell, PhD MSc, BSc, Erin Flynt, Anjan Thakurta, Gareth Morgan, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 4346.
https://doi.org/10.1182/blood-2019-130079
Published: 2019
Journal Articles

Chromoplexy and Chromothripsis Are Important Prognostically in Myeloma and Deregulate Gene Function By a Range of Mechanisms

Cody Ashby, PhD, Eileen M Boyle, MD MSc, Brian A Walker, PhD, Michael A Bauer, PhD, Katie Rose Ryan, PhD, Judith Dent, Anjan Thakurta, Erin Flynt, Faith E. Davies, MD, Gareth Morgan, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 3767.
https://doi.org/10.1182/blood-2019-130335
Published: 2019
Journal Articles

Analysis of the Sub-Clonal Structure of Smoldering Myeloma over Time Provides a New Means of Disease Monitoring and Highlights Evolutionary Trajectories Leading to Myeloma

Eileen M Boyle, MD MSc, Faith E. Davies, MD, Shayu Deshpande, Ruslana G. Tytarenko, MS, Cody Ashby, PhD, Yan Wang, Christopher P. Wardell, PhD MSc, BSc, Michael A Bauer, PhD, Sarah K Johnson, PhD, Carolina D. Schinke, MD, Sharmilan Thanendrarajan, MD, Frits van Rhee, MD PhD, Maurizio Zangari, MD, Louis Williams, MD MBA, Thierry Facon, MD, Charles Dumontet, Bart Barlogie, MD PhD, Gareth Morgan, MDPhDFRCP, Brian A Walker, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 4333.
https://doi.org/10.1182/blood-2019-126679
Published: 2019
Journal Articles

The genomic landscape of plasma cells in systemic light chain amyloidosis

Eileen M. Boyle, Cody Ashby, Christopher P. Wardell, Dorota Rowczenio, Sajitha Sachchithanantham, Yan Wang, Sarah K. Johnson, Michael A. Bauer, Niels Weinhold, Martin F. Kaiser, David C. Johnson, John R. Jones, Charlotte Pawlyn, Paula Proszek, Carolina Schinke, Thierry Facon, Charles Dumontet, Faith E. Davies, Gareth J. Morgan, Brian A. Walker, Ashutosh D. Wechalekar
Journal: Blood
Blood (2018) 132 (26): 2775–2777.
https://doi.org/10.1182/blood-2018-08-872226
Published: 2018
Includes: Supplemental data
Journal Articles

Combination of Flow Cytometry and Functional Imaging for Monitoring of Residual Disease in Myeloma

Leo Rasche, Daisy Alapat, MD, Manoj Kumar, MD, Grant Gershner, James E McDonald, BS, MD, Christopher P. Wardell, PhD MSc, BSc, Samrat Roy Choudhury, PhD, Rudy L. Van Hemert, MD, Joshua Epstein, DSc, Amy F Williams, Sharmilan Thanendrarajan, MD, Carolina D. Schinke, MD, Michael A Bauer, PhD, Cody Ashby, PhD, Ruslana G. Tytarenko, MS, Frits van Rhee, MD PhD, Brian A Walker, PhD, Maurizio Zangari, MD, Bart Barlogie, MD PhD, Faith E. Davies, MD, Gareth Morgan, MD, Niels Weinhold, PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 3185.
https://doi.org/10.1182/blood-2018-99-119249
Published: 2018
Journal Articles

Chromothripsis and Chromoplexy Are Associated with DNA Instability and Adverse Clinical Outcome in Multiple Myeloma

Cody Ashby, PhD, Michael A Bauer, PhD, Yan Wang, Christopher P. Wardell, PhD MSc, BSc, Ruslana G. Tytarenko, MS, Purvi Patel, Erin Flynt, Maria Ortiz, Andrew Dervan, Jake Gockley, PhD, Aneta Mikulasova, PhD, Carolina D. Schinke, MD, Sharmilan Thanendrarajan, MD, Maurizio Zangari, MD, Frits van Rhee, MD PhD, Faith E. Davies, MD, Jonathan J Keats, PhD, Daniel Auclair, PhD, Anjan Thakurta, PhD, Brian A Walker, PhD, Gareth Morgan, MD
Journal: Blood
Blood (2018) 132 (Supplement 1): 408.
https://doi.org/10.1182/blood-2018-99-117359
Published: 2018
Journal Articles

Expression Signature of Myeloma Residual Cells Is Characterized By Genes Associated with Proliferation, Epigenetic Modification, and Stem Cell Maintenance

Michael A Bauer, PhD, Matthew Henry, M.S., Purvi Patel, Yan Wang, Joshua Epstein, DSc, Faith E. Davies, MD, Carolina D. Schinke, MD, Maurizio Zangari, MD, Sharmilan Thanendrarajan, MD, Frits van Rhee, MD PhD, Gareth Morgan, MD, Brian A Walker, PhD, Sarah K Johnson, PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 4465.
https://doi.org/10.1182/blood-2018-99-119131
Published: 2018
Journal Articles

Mutations and Copy Number Changes Predict Progression from Smoldering Myeloma to Symptomatic Myeloma in the Era of Novel IMWG Criteria

Eileen M Boyle, MD MSc, Cody Ashby, PhD, Ruslana G. Tytarenko, MS, Yan Wang, Michael A Bauer, PhD, Shayu Deshpande, Sarah K Johnson, PhD, Carolina D. Schinke, MD, Sharmilan Thanendrarajan, MD, Frits van Rhee, MD PhD, Christopher Wardell, PhD, Niels Weinhold, PhD, Thierry Facon, Charles Dumontet, Gareth Morgan, MD, Faith E. Davies, MD, Brian A Walker, PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 4456.
https://doi.org/10.1182/blood-2018-99-117193
Published: 2018
Journal Articles

Global Expression Changes of Malignant Plasma Cells over Time Reveals the Evolutionary Development of Signatures of Aggressive Clinical Behavior

Eileen M Boyle, MD MSc, Adam Rosenthal, MS, Yan Wang, Phil Farmer, Michael W Rutherford, Cody Ashby, PhD, Michael A Bauer, PhD, Sarah K Johnson, PhD, Christopher P. Wardell, PhD MSc, BSc, Niels Weinhold, PhD, Antje Hoering, PhD, Charles Dumontet, Thierry Facon, Carolina D. Schinke, MD, Sharmilan Thanendrarajan, MD, Frits van Rhee, MD PhD, Maurizio Zangari, MD, Bart Barlogie, MD PhD, Faith E. Davies, MD, Brian A Walker, PhD, Gareth Morgan, MD
Journal: Blood
Blood (2018) 132 (Supplement 1): 4457.
https://doi.org/10.1182/blood-2018-99-119113
Published: 2018