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Purvi Patel
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Journal Articles

Chromothripsis and Chromoplexy Are Associated with DNA Instability and Adverse Clinical Outcome in Multiple Myeloma

Cody Ashby, PhD, Michael A Bauer, PhD, Yan Wang, Christopher P. Wardell, PhD MSc, BSc, Ruslana G. Tytarenko, MS, Purvi Patel, Erin Flynt, Maria Ortiz, Andrew Dervan, Jake Gockley, PhD, Aneta Mikulasova, PhD, Carolina D. Schinke, MD, Sharmilan Thanendrarajan, MD, Maurizio Zangari, MD, Frits van Rhee, MD PhD, Faith E. Davies, MD, Jonathan J Keats, PhD, Daniel Auclair, PhD, Anjan Thakurta, PhD, Brian A Walker, PhD, Gareth Morgan, MD
Journal: Blood
Blood (2018) 132 (Supplement 1): 408.
https://doi.org/10.1182/blood-2018-99-117359
Published: 2018
Journal Articles

Global 3D-Epigenetic Dysregulation of Cyclin D1 and D2 Actively Controls Their Expression Pattern in Multiple Myeloma

Samrat Roy Choudhury, PhD, Cody Ashby, PhD, Ruslana G. Tytarenko, MS, Yan Wang, Purvi Patel, Katie Rose Ryan, PhD, Judith A Dent, Faith E. Davies, MD, Gareth Morgan, MD, Brian A Walker, PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 3904.
https://doi.org/10.1182/blood-2018-99-115547
Published: 2018
Journal Articles

Expression Signature of Myeloma Residual Cells Is Characterized By Genes Associated with Proliferation, Epigenetic Modification, and Stem Cell Maintenance

Michael A Bauer, PhD, Matthew Henry, M.S., Purvi Patel, Yan Wang, Joshua Epstein, DSc, Faith E. Davies, MD, Carolina D. Schinke, MD, Maurizio Zangari, MD, Sharmilan Thanendrarajan, MD, Frits van Rhee, MD PhD, Gareth Morgan, MD, Brian A Walker, PhD, Sarah K Johnson, PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 4465.
https://doi.org/10.1182/blood-2018-99-119131
Published: 2018
Journal Articles

Long-Term Follow-up Identifies Double Hit and Key Mutations As Impacting Progression Free and Overall Survival in Multiple Myeloma

Cody Ashby, PhD, Eileen Boyle, Ruslana G. Tytarenko, MS, Hongwei Wang, MS, Adam Rosenthal, MS, Purvi Patel, Yan Wang, Shayu Deshpande, Maria Ortiz, Erin Flynt, Antje Hoering, PhD, Sharmilan Thanendrarajan, MD, Carolina D. Schinke, MD, Maurizio Zangari, MD, Frits van Rhee, MD PhD, Bart Barlogie, MD PhD, Anjan Thakurta, PhD, Gareth Morgan, MD, Brian A Walker, PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 110.
https://doi.org/10.1182/blood-2018-99-113045
Published: 2018
Journal Articles

Extracting Prognostic Molecular Information from PET-CT Imaging of Multiple Myeloma Using Radiomic Approaches

Christopher Wardell, PhD, Terri Lynn Alpe, Phil Farmer, Michael W Rutherford, Yan Wang, Niels Weinhold, PhD, Ruslana G. Tytarenko, MS, Purvi Patel, Michael A Bauer, PhD, Cody Ashby, PhD, Eileen M Boyle, MD MSc, Carolina D. Schinke, MD, Sharmilan Thanendrarajan, MD, Frits van Rhee, MD PhD, Maurizio Zangari, MD, Brian A Walker, PhD, Gareth Morgan, MD, Faith E. Davies, MD
Journal: Blood
Blood (2018) 132 (Supplement 1): 1906.
https://doi.org/10.1182/blood-2018-99-117103
Published: 2018
Journal Articles

Whole Genome Sequencing Reveals the Extent of Structural Variants in Multiple Myeloma and Identifies Recurrent Mutational Hotspots within the Non-Coding Regions

Cody Cody Ashby, PhD, Michael Bauer, PhD, Owen W. Stephens, Christopher P. Wardell, PhD, Ruslana G. Tytarenko, MS, Aneta Mikulasova, PhD, Purvi Patel, Shayu Deshpande, Frits van Rhee, MD PhD, Maurizio Zangari, MD, Sharmilan Thanendrarajan, MD, Carolina D. Schinke, MD, Niels Weinhold, PhD, Leo Rasche, MD, Faith E Davies, MD, Gareth J. Morgan, MD PhD, Brian A Walker, PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 3032.
https://doi.org/10.1182/blood.V130.Suppl_1.3032.3032
Published: 2017
Journal Articles

High Risk Myeloma Is Characterized By the Bi-Allelic Inactivation of CDKN2C and RB1

Shweta S. Chavan, PhD, Christoph Heuck, MD, Jie He, PhD, Rusiana Tytarenko, Shayu Deshpande, PhD, Purvi Patel, Mark Bailey, MSc, Caleb K. Stein, MS, Owen W Stephens, Niels Weinhold, PhD, Nathan Petty, MS, Doug Steward, Leo Rasche, MD, Michael A Bauer, PhD, Cody Ashby, PhD, Erich Allen Peterson, PhD BS, MS, Shan Zhong, PhD, Michelle Nahas, PhD, Siraj M Ali, MD PhD, Jo-Anne Vergillo, MD, Jeff Ross, MD, Vincent A. Miller, MD, Phillip J Stephens, PhD, Carolina Schinke, MD, Maurizio Zangari, MD, Frits van Rhee, MD PhD, Bart Barlogie, MD PhD, Tariq I Mughal, MD, Faith E Davies, MD, Gareth J Morgan, MD PhD, Brian A Walker, PhD
Journal: Blood
Blood (2016) 128 (22): 4416.
https://doi.org/10.1182/blood.V128.22.4416.4416
Published: 2016
Journal Articles

A Survey of Fusion Genes in Myeloma Identifies Kinase Domain Activation Which Could be Targeted with Available Treatments

Brian A Walker, PhD, Shweta S. Chavan, PhD, Jie He, PhD, Ruslana Tytarenko, Shan Zhong, PhD, Shayu Deshpande, PhD, Purvi Patel, Caleb K. Stein, MS, Owen W Stephens, Niels Weinhold, PhD, Nathan Petty, MS, Doug Steward, Carolina Schinke, MD, Leo Rasche, MD, Mark Bailey, MSc, Siraj Ali, Jo-Anne Vergillo, MD, Jeff Ross, MD, Vincent A. Miller, MD, Phillip J Stephens, PhD, Sharmilan Thanendrarajan, MD, Maurizio Zangari, MD, Frits van Rhee, MD PhD, Tariq I Mughal, MD, Faith E Davies, MD, Gareth J Morgan, MDPhD
Journal: Blood
Blood (2016) 128 (22): 117.
https://doi.org/10.1182/blood.V128.22.117.117
Published: 2016
Journal Articles

Next Generation Sequencing (NGS) Based Minimal Residual Disease (MRD) Testing Is Highly Predictive of Overall and Progression Free Survival in the Total Therapy Trials and Shows Different Prognostic Implications in High Vs Standard Risk Multiple Myeloma

Carolina Schinke, MD, Shayu Deshpande, PhD, Hongwei Wang, Victoria Carlton, PhD, Katherine A. Kong, PhD, Martin Moorhead, PhD, Tom Willis, Purvi Patel, Sharmilan Thanendrarajan, MD, Meera Mohan, MD, Pankaj Mathur, MD, Sandra Susanibar, MD, Shadiqul Hoque, MD, Muthukumar Radhakrishnan, MD, Ruslana Tytarenko, Owen W Stephens, Leo Rasche, MD, Frits van Rhee, MD PhD, Maurizio Zangari, MD, Nathan Petty, MS, Daisy V. Alapat, MD, Sarah K. Johnson, PhD, Joshua Epstein, DSc, Bart Barlogie, MD PhD, Faith E Davies, MD, Antje Hoering, PhD, Niels Weinhold, PhD, Gareth J Morgan, MD PhD
Journal: Blood
Blood (2016) 128 (22): 2064.
https://doi.org/10.1182/blood.V128.22.2064.2064
Published: 2016
Journal Articles

Extensive Regional Intra-Clonal Heterogeneity in Multiple Myeloma - Implications for Diagnostics, Risk Stratification and Targeted Treatment

Niels Weinhold, PhD, Shweta S. Chavan, PhD, Leo Rasche, MD, Owen W Stephens, Purvi Patel, Ruslana Tytarenko, Cody Ashby, PhD, Caleb K. Stein, MS, Michael A Bauer, PhD, Christopher P Wardell, PhD, Shayu Deshpande, PhD, Timea Buzder, Gabor Molnar, Frits van Rhee, MD PhD, Maurizio Zangari, MD, Sharmilan Thanendrarajan, MD, Brian A Walker, PhD, Shmuel Yaccoby, PhD, Sarah K. Johnson, PhD, Joshua Epstein, DSc, Bart Barlogie, MD PhD, Christoph Heuck, MD, Faith E Davies, MD, Tobias Meissner, PhD, Gareth J Morgan, MD PhD
Journal: Blood
Blood (2016) 128 (22): 3278.
https://doi.org/10.1182/blood.V128.22.3278.3278
Published: 2016
Journal Articles

Impact of Minimal Residual Disease in High and Standard Risk Multiple Myeloma

Carolina Schinke, MD, Shayu Deshpande, PhD, Alan Mitchell, Malek Faham, Purvi Patel, Sharmilan Thanendrarajan, MD, Meera Mohan, Pankaj Mathur, Aasiya Matin, Muthukumar Radhakrishnan, Ruslana Tytarenko, Owen W Stephens, PhD, Frits van Rhee, MD PhD, Maurizio Zangari, MD, Yogesh Jethava, MD, Nathan Petty, MS, Daisy V. Alapat, MD, Sarah K. Johnson, PhD, Joshua Epstein, DSc, Bart Barlogie, MD PhD, Faith E Davies, MD, Christoph Heuck, MD, Antje Hoering, Niels Weinhold, PhD, Gareth J Morgan, MDPhD
Journal: Blood
Blood (2015) 126 (23): 2979.
https://doi.org/10.1182/blood.V126.23.2979.2979
Published: 2015
Journal Articles

Comparing Gene Expression Profiling (GEP) Features Of Bone Marrow Biopsies (BMBx) Of Patients With Multiple Myeloma (MM) and Normal Donors (NL): 24 Microenvironment Specific Gene Probes Distinguish MM From NL

Christoph Heuck, MD, Pingping Qu, PhD, Emily Hansen, MS, Qing Zhang, PhD, Adam Rosenthal, Frits van Rhee, MD, PhD, Sarah Waheed, MD, Shebli Atrash, MD, Purvi Patel, Antje Hoering, PhD, Joshua Epstein, John Crowley, PhD, Bart Barlogie, MD, PhD
Journal: Blood
Blood (2013) 122 (21): 1913.
https://doi.org/10.1182/blood.V122.21.1913.1913
Published: 2013