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Journal Articles

Pharmacological Inhibition of miR-126 Enhances Venetoclax Activity in Acute Myeloid Leukemia

Available to Purchase
Lianjun Zhang, HyunJun Kang, Melissa Valerio, Dinh Hoa Hoang, Khyatiben V. Pathak, Krystine Garcia-Mansfield, Xiyuan Lu, Wancheng Guo, Yu-Hsuan Fu, Xin He, Ying-Chieh Chen, Zhenhua Chen, Lucy Y. Ghoda, Ralf Buettner, Zhuo Li, Amanda Blackmon, Ling Li, Bin Zhang, Patrick Pirrotte, Guido Marcucci, Ya-Huei Kuo, Le Xuan Truong Nguyen
Journal: Blood
Blood blood.2025029875.
https://doi.org/10.1182/blood.2025029875
Published: 2025
Includes: Supplemental data
Journal Articles

2025 Update on MRD in Acute Myeloid Leukemia: A Consensus Document from the ELN-DAVID MRD Working Party

Open Access
Jacqueline Cloos, Peter J.M. Valk, Christian Thiede, Konstanze Döhner, Gail J Roboz, Brent L. Wood, Roland B. Walter, Sa A Wang, Agnieszka Wierzbowska, Andrew H Wei, David Wu, Francois Vergez, Adriano Venditti, Bert A. van der Reijden, Arjan A van de Loosdrecht, Ing Soo Tiong, Felicitas R Thol, Marion Subklewe, Christophe Roumier, Tom Reuvekamp, Farhad Ravandi, Claude Preudhomme, Adriana Plesa, Jad Othman, Gert J. Ossenkoppele, Yishai Ofran, Aguirre Mimoun, Luca Maurillo, Agata Majchrzak, David C. de Leeuw, Wolfgang Kern, Dennis Dong Hwan Dong Hwan Kim, Maura Rosane Valério Ikoma-Colturato, Lukas H. Haaksma, Monica L Guzman, Michaela Feuring, Barbara Depreter, Anna Czyz, Veit L. Bücklein, Constance Baer, Costa Bachas, Sylvie D Freeman, Francesco Buccisano, Christopher S Hourigan, Richard James Dillon, Michael Heuser
Journal: Blood
Blood blood.2025031480.
https://doi.org/10.1182/blood.2025031480
Published: 2025
Includes: Supplemental data
Journal Articles

Asciminib Demonstrates Superior Efficacy and Safety in Newly Diagnosed Chronic Myeloid Leukemia in the ASC4FIRST Trial

Open Access
Clinical Trials & Observations
Jorge E. Cortes, Timothy P Hughes, Jianxiang Wang, Dong-Wook Kim, Dennis Dong Hwan Kim, Jiri Mayer, Yoew-Tee Goh, Philipp le Coutre, Gabriel Etienne, Inho Kim, David Andorsky, Felice Bombaci, Ghayas C. Issa, Naoto Takahashi, Shruti Kapoor, Rajendra Jinwal, Kamel Malek, Tracey McCulloch, Lillian Yau, Richard A Larson, Andreas Hochhaus
Journal: Blood
Blood blood.2025029210.
https://doi.org/10.1182/blood.2025029210
Published: 2025
Includes: Supplemental data
Journal Articles

Microenvironmental cell interactions are essential for sustaining functionality of myelofibrosis malignant stem cells

Open Access
Min Lu, Md. Babu Mia, Lijuan Xia, Gohar Mosoyan, Momina Hayat, Christoph Schaniel, Ronald Hoffman
Journal: Blood
Blood blood.2025031454.
https://doi.org/10.1182/blood.2025031454
Published: 2025
Includes: Supplemental data
Journal Articles

Transient SP140 inhibition unlocks hematopoietic stem cell fate from human pluripotent stem cells

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Xingjie Liu, Zhiwei Zhang, Xinyu Cui, Rui Guo, Xiaoyan Ding, Liyang Ma, Pentao Liu, Yong Yu
Journal: Blood
Blood blood.2025032084.
https://doi.org/10.1182/blood.2025032084
Published: 2025
Includes: Multimedia, Supplemental data
Journal Articles

Methylation-based lineage tracing in cancer

Open Access
Clinical Trials & Observations
Jiaoyi Chen, Benson Z Wu, Federico Gaiti
Journal: Blood
Blood blood.2025028196.
https://doi.org/10.1182/blood.2024028196
Published: 2025
Journal Articles

Orca-T versus allogeneic hematopoietic stem cell transplantation (PRECISION-T): a multicenter, randomized phase 3 trial

Open Access
Clinical Trials & Observations
Everett Meyer, Amandeep Salhotra, Arpita Gandhi, Jeremy Pantin, Sagar S. Patel, Rasmus T. Hoeg, Alexandra Gomez-Arteaga, Rawan G. Faramand, Roni Tamari, Edmund K Waller, Satyajit Kosuri, Antonio M Jimenez Jimenez, Jennifer Holter-Chakrabarty, Bhagirathbhai Dholaria, Yi-Bin Chen, Betty K. Hamilton, John M Magenau, Alireza Eghtedar, Joshua M Murray, Anna Pavlova, Nathaniel B Fernhoff, James Scott McClellan, Scott Killian, Ai Li, Robert S. Negrin, Caspian Oliai
Journal: Blood
Blood blood.2025031313.
https://doi.org/10.1182/blood.2025031313
Published: 2025
Includes: Supplemental data
Journal Articles

Layilin inhibits integrin activation, and its loss results in platelet hyperactivation via Rac1 in inflammatory bowel disease

Available to Purchase
Rebecca A. Mellema, Kimberly A. Queisser, Abigail Ajanel, Nansy Albtoush, Lydia Smith-Sanchez, Matthew T. Rondina, Julie Will, John F. Valentine, Aaron C. Petrey
Journal: Blood
Blood (2025) 146 (24): 2979–2992.
https://doi.org/10.1182/blood.2025028477
Published: 2025
Includes: Supplemental data
Journal Articles

Platelet heterogeneity: variety makes immune and vascular function better

Available to Purchase
Michael W. Malloy, Kathleen E. McGrath, Craig N. Morrell
Journal: Blood
Blood (2025) 146 (24): 2882–2888.
https://doi.org/10.1182/blood.2025028955
Published: 2025
Journal Articles

Platelet heterogeneity in disease: the many and the diverse?

Available to Purchase
Rainer Kaiser, Afra Anjum, Leo Nicolai
Journal: Blood
Blood (2025) 146 (24): 2870–2881.
https://doi.org/10.1182/blood.2025028957
Published: 2025
Journal Articles

Talquetamab plus daratumumab for the treatment of relapsed or refractory multiple myeloma in the TRIMM-2 study

Available to Purchase
Clinical Trials & Observations
Ajai Chari, Niels W. C. J. van de Donk, Bhagirathbhai Dholaria, Katja Weisel, María-Victoria Mateos, Hartmut Goldschmidt, Thomas G. Martin, Daniel Morillo, Donna Reece, Paula Rodríguez-Otero, Manisha Bhutani, Anita D’Souza, Albert Oriol, Laura Rosiñol, Nizar J. Bahlis, Deeksha Vishwamitra, Sheri Skerget, Raluca I. Verona, Kalpana Bakshi, Lijuan Kang, Thomas J. Prior, Lien Vandenberk, Jaszianne Tolbert, Sangmin Lee, M. Damiette Smit, Ralph Wäsch
Journal: Blood
Blood (2025) 146 (24): 2902–2913.
https://doi.org/10.1182/blood.2025029360
Published: 2025
Includes: Supplemental data
Journal Articles

Clinical and research methods for analysis and study of platelet populations

Available to Purchase
Thomas Thiele, Johan W. M. Heemskerk, Andrew L. Frelinger, III
Journal: Blood
Blood (2025) 146 (24): 2889–2901.
https://doi.org/10.1182/blood.2025028956
Published: 2025
Includes: Supplemental data
Journal Articles

Introduction to a review series on platelet heterogeneity

Free
Elisabeth M. Battinelli
Journal: Blood
Blood (2025) 146 (24): 2847.
https://doi.org/10.1182/blood.2025031637
Published: 2025
Journal Articles

Neutrophils fine-tune the NET effects of activation

Free
Marie Siwicki, Paul Kubes
Journal: Blood
Blood (2025) 146 (24): 2861–2862.
https://doi.org/10.1182/blood.2025031149
Published: 2025
Journal Articles

Layilin: a novel regulator of platelet reactivity in IBD

Free
Martin Schlesinger
Journal: Blood
Blood (2025) 146 (24): 2859–2860.
https://doi.org/10.1182/blood.2025030854
Published: 2025
Journal Articles

Less CUX1, more retroelements: inflammation fuels stemness

Free
Françoise Porteu
Journal: Blood
Blood (2025) 146 (24): 2852–2853.
https://doi.org/10.1182/blood.2025031226
Published: 2025
Journal Articles

Glu(tamine)ing together myeloma metabolism and CAR T efficacy

Free
Arun P. Wiita
Journal: Blood
Blood (2025) 146 (24): 2854–2855.
https://doi.org/10.1182/blood.2025031096
Published: 2025
Journal Articles

Luminal hepcidin targets intestinal DMT1

Free
James F. Collins
Journal: Blood
Blood (2025) 146 (24): 2849–2850.
https://doi.org/10.1182/blood.2025031293
Published: 2025
Journal Articles

Enhancing the targeting of the undruggable

Free
Benjamin G. Barwick, Lawrence H. Boise
Journal: Blood
Blood (2025) 146 (24): 2855–2857.
https://doi.org/10.1182/blood.2025031097
Published: 2025
Journal Articles

Defusing AML: targeting t(8;21) forces myeloid maturation

Free
Esther A. Obeng
Journal: Blood
Blood (2025) 146 (24): 2857–2859.
https://doi.org/10.1182/blood.2025031252
Published: 2025