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Journal Articles

A phase 2 randomized study of modakafusp alfa as a single agent in patients with relapsed/refractory multiple myeloma

Clinical Trials & Observations
Sarah A Holstein, Shebli Atrash, Hira Mian, Meletios Athanasios Dimopoulos, Fredrik Schjesvold, Rakesh Popat, Nishi Shah, Moshe E Gatt, Christian B. Gocke, Laurent Frenzel, Cyrille Touzeau, Meral Beksac, Salomon Manier, Hila Magen, Patrick Travis, Omar Nadeem, Kaveri Suryanarayan, Cheryl Li, Shuli Li, Allison Nelson, Dasha Cherepanov, Xavier Parot, Dan T Vogl
Journal: Blood
Blood blood.2024027873.
https://doi.org/10.1182/blood.2024027873
Published: 2025
Includes: Supplemental data
Journal Articles

Clinical phenotype and pathophysiological mechanisms underlying qualitative Low VWF

Ferdows Atiq, Robin Blok, Calvin van Kwawegen, Anne-Marije Hulshof, Dearbhla Doherty, Michelle Lavin, Johanna G van der Bom, Niamh M O'Connell, Joke de Meris, Kevin Ryan, Saskia E.M. Schols, Waander L. van Heerde, Mairead M Doyle, Mary B Byrne, Floor C.J.I. Heubel-Moenen, Karin P.M. van Galen, Roger J.S. Preston, Marjon H. Cnossen, Karin Fijnvandraat, Prof, Ross Ian Baker, Karina Meijer, Paula D. James, Jorge Di Paola, Jeroen C.J. Eikenboom, Frank W.G. Leebeek, James S. O'Donnell
Journal: Blood
Blood blood.2024028035.
https://doi.org/10.1182/blood.2024028035
Published: 2025
Includes: Supplemental data
Journal Articles

CAR T cells in autoimmunity: game changer or stepping stone?

Clinical Trials & Observations
Dimitrios Mougiakakos, Everett H. Meyer, Georg Schett
Journal: Blood
Blood (2025) 145 (17): 1841–1849.
https://doi.org/10.1182/blood.2024025413
Published: 2025
Includes: Supplemental data
Journal Articles

Non-V600E BRAF mutations and treatment for hairy cell leukemia

Evgeny Arons, Chin-Hsien Tai, Joshi Suraj, Yuelin Liu, Chi-Ping Day, Mark Raffeld, Liqiang Xi, Hong Zhou, Mory Gould, Isaac Shpilman, Cristopher C. Oakes, Seema Bhat, Michael Grever, Daniel Jones, Kerry Rogers, Hao-Wei Wang, Constance M. Yuan, Cenk Sahinalp, Robert J. Kreitman
Journal: Blood
Blood (2025) 145 (17): 1957–1961.
https://doi.org/10.1182/blood.2024026894
Published: 2025
Includes: Supplemental data
Journal Articles

Targeting Enterobacter cloacae attenuates osteolysis by reducing ammonium in multiple myeloma

Qin Yang, Yinghong Zhu, Xingxing Jian, Yi Qiu, Yan Zhu, Lia Zhao, Yanjuan He, Gang An, Lugui Qiu, Jiaojiao Guo, Nihan He, Huerxidan Abudumijiti, Cong Hu, Xun Chen, Siqing Huang, Xiangling Feng, Xin Li, Jing Liu, Yajing Xu, Wen Zhou
Journal: Blood
Blood (2025) 145 (17): 1876–1889.
https://doi.org/10.1182/blood.2024025694
Published: 2025
Includes: Supplemental data
Journal Articles

Prognostic and therapeutic implications of measurable residual disease levels during remission induction of childhood ALL

Clinical Trials & Observations
Weina Zhang, Jiaoyang Cai, Xiang Wang, Yani Ma, Xiaofan Zhu, Jie Yu, Peifang Xiao, Ju Gao, Yongjun Fang, Changda Liang, Xue Li, Fen Zhou, Xiaowen Zhai, Xiaoxiao Xu, Xin Tian, Aiguo Liu, Ningling Wang, Jiashi Zhu, Lingzhen Wang, Frankie Wai-Tsoi Cheng, Liangchun Yang, Ge Zhang, Cheng Cheng, Jun J. Yang, Shuhong Shen, Chi-kong Li, Benshang Li, Hua Jiang, Ching-Hon Pui
Journal: Blood
Blood (2025) 145 (17): 1890–1902.
https://doi.org/10.1182/blood.2024026381
Published: 2025
Includes: Supplemental data
Journal Articles

Glucarpidase for treatment of high-dose methotrexate toxicity

Clinical Trials & Observations
Shruti Gupta, Sarah A. Kaunfer, Kevin L. Chen, Julie-Alexia Dias, Anitha Vijayan, Arun Rajasekaran, Jason M. Prosek, Huong L. Truong, Anthony Wood, Claude Bassil, Amanda D. Renaghan, Chintan V. Shah, Jingjing Zhang, Ilya Glezerman, Christopher Carlos, Katherine Kelly, Christopher J. Passero, Jan Drappatz, Ala Abudayyeh, Daniel Sanghoon Shin, C. John Sperati, Bradley J. Yelvington, Swetha R. Kanduri, Javier A. Neyra, Daniel Edmonston, Anushree C. Shirali, Anip Bansal, Abdallah Geara, Zain Mithani, Susan L. Ziolkowski, Arash Rashidi, Jonathan Jakubowski, Ashwini Pujari, David A. Bond, Emily Dotson, Sarah Wall, John Patton, Jason N. Barreto, Sandra M. Herrmann, Mohammad S. Sheikh, Rachid Baz, Jamie Lee, Nicholas Lucchesi, Michael Kolman, Muhammad Ahsan Rasheed, Afsheen Afzal, Dasol Kang, Amrita Mahesh, Raymond K. Hsu, Anthony Nicolaysen, Kibrewessen Tefera, Claire Schretlen, Ryan M. Miller, Juan Carlos Velez, Alexander H. Flannery, Abinet M. Aklilu, Shuchi Anand, Soniya Chandrasekhara, Vicki Donley, Ashka Patel, Jian Ni, Shobana Krishnamurthy, Rafia Ali, Osman A. Yilmam, Sophia L. Wells, Jessica L. Ortega, Olivia L. Green-Lingren, Rebecca K. Leaf, Meghan E. Sise, Lakshmi Nayak, Ann S. LaCasce, Nelson Leung, David E. Leaf
Journal: Blood
Blood (2025) 145 (17): 1858–1869.
https://doi.org/10.1182/blood.2024026211
Published: 2025
Includes: Supplemental data
Journal Articles

Common hereditary variants of the APOE gene and posttransplant outcome in acute myeloid leukemia

Clinical Trials & Observations
Julian Ronnacker, Michael Grau, Maximilian Klasmeier, Christian Klesse, Henning Baldauf, Stefan Abert, Andrew F. Berdel, Friederike T. Füsser, Sarah Sandmann, Jörn Albring, Christian Reicherts, Simon Call, Julia Marx, Matthias Floeth, Eva Eßeling, Lina Kolloch, Philipp Berning, Annika Scheller, Klaus Wethmar, Hartmut Schmidt, Bernhard Schlüter, Wolfgang E. Berdel, Benjamin N. Ostendorf, Sohail F. Tavazoie, Jan-Henrik Mikesch, Georg Lenz, Katharina Fleischhauer, Johannes Schetelig, Matthias Stelljes, Christoph Schliemann
Journal: Blood
Blood (2025) 145 (17): 1943–1956.
https://doi.org/10.1182/blood.2024026886
Published: 2025
Includes: Supplemental data
Journal Articles

Functional assessment of genetic variants in thrombomodulin detected in patients with bleeding and thrombosis

Christine Van Laer, Renaud Lavend’homme, Sarissa Baert, Koenraad De Wispelaere, Chantal Thys, Cyrielle Kint, Sam Noppen, Kathelijne Peerlinck, Chris Van Geet, Dominique Schols, Thomas Vanassche, Veerle Labarque, Peter Verhamme, Marc Jacquemin, Kathleen Freson
Journal: Blood
Blood (2025) 145 (17): 1929–1942.
https://doi.org/10.1182/blood.2024026454
Published: 2025
Includes: Supplemental data
Journal Articles

PSTK inhibition activates cGAS-STING, precipitating ferroptotic cell death in leukemic stem cells

Lingli He, Ting Zhao, Wei Zhong Leong, Azeem Sharda, Christina Mayerhofer, Shenglin Mei, Gracia M. Bonilla, Juan Bautista Menendez-Gonzalez, Karin Gustafsson, Tsuyoshi Fukushima, Trine A. Kristiansen, Ji-Won Lee, Yanxin Xu, Lei Chen, Jun Xia, Luis Angel Orozco, Bogdan Budnik, Ruslan Sadreyev, Zhixun Dou, David B. Sykes, David T. Scadden
Journal: Blood
Blood (2025) 145 (17): 1903–1914.
https://doi.org/10.1182/blood.2024026040
Published: 2025
Includes: Supplemental data
Journal Articles

Venetoclax plus daunorubicin and cytarabine for newly diagnosed acute myeloid leukemia: results of a phase 1b study

Clinical Trials & Observations Brief Report
Ioannis Mantzaris, Mendel Goldfinger, Matan Uriel, Aditi Shastri, Nishi Shah, Kira Gritsman, Noah S. Kornblum, Lauren Shapiro, Roberto Alejandro Sica, Anne Munoz, Nicole Chambers, Aradhika Dhawan, Jhannine Alyssa Verceles, Karen Fehn, Balda Tirone, Lamisha Shah, Shaunmonique Clark, Chenxin Zhang, Mimi Kim, Dennis L. Cooper, Amit Verma, Marina Konopleva, Eric J. Feldman
Journal: Blood
Blood (2025) 145 (17): 1870–1875.
https://doi.org/10.1182/blood.2024026700
Published: 2025
Includes: Supplemental data
Journal Articles

17( R )-Resolvin D1 protects against sickle cell–related inflammatory cardiomyopathy in humanized mice

Enrica Federti, Domenico Mattoscio, Antonio Recchiuti, Alessandro Matte, Maria Monti, Flora Cozzolino, Manuela Iezzi, Martina Ceci, Alessandra Ghigo, Emanuela Tolosano, Angela Siciliano, Jacopo Ceolan, Veronica Riccardi, Elisa Gremese, Carlo Brugnara, Lucia De Franceschi
Journal: Blood
Blood (2025) 145 (17): 1915–1928.
https://doi.org/10.1182/blood.2024024768
Published: 2025
Includes: Supplemental data
Journal Articles

STINGing leukemia stem cells through PSTK inhibition

Sylvain Garciaz
Journal: Blood
Blood (2025) 145 (17): 1833–1835.
https://doi.org/10.1182/blood.2024028046
Published: 2025
Journal Articles

17( R )-Resolvin D1: a novel approach for SCD cardiomyopathy

Thilina U. Jayawardena, Gavin Y. Oudit
Journal: Blood
Blood (2025) 145 (17): 1835–1837.
https://doi.org/10.1182/blood.2025028490
Published: 2025
Journal Articles

Methotrexate and glucarpidase: the emperor has new clothes

Clinical Trials & Observations
Stefan Schwartz, Jesper Heldrup
Journal: Blood
Blood (2025) 145 (17): 1829–1830.
https://doi.org/10.1182/blood.2024027791
Published: 2025
Journal Articles

Beyond conVENtional 7+3 in acute myeloid leukemia

Clinical Trials & Observations
Christine M. McMahon
Journal: Blood
Blood (2025) 145 (17): 1831–1832.
https://doi.org/10.1182/blood.2025028442
Published: 2025
Journal Articles

Thrombophilic thrombomodulin variants

Elisabetta Castoldi
Journal: Blood
Blood (2025) 145 (17): 1837–1839.
https://doi.org/10.1182/blood.2024027934
Published: 2025
Journal Articles

Recycling is “bad to the bone” in patients with myeloma

Kevin C. Miller, Alexander M. Lesokhin
Journal: Blood
Blood (2025) 145 (17): 1832–1833.
https://doi.org/10.1182/blood.2024027940
Published: 2025
Journal Articles

Seeing is believing: a histology textbook’s dream case of sarcoidosis

Pravin Patel, Olga Pozdnyakova
Journal: Blood
Blood (2025) 145 (17): 1962.
https://doi.org/10.1182/blood.2025028699
Published: 2025
Journal Articles

A new variable to study in transplant: APOE variant status

Satoshi Kaito, Susan DeWolf
Journal: Blood
Blood (2025) 145 (17): 1839–1840.
https://doi.org/10.1182/blood.2025028406
Published: 2025