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Journal Articles

Sickle Cell Trait Does Not Cause "Sickle Cell Crisis" Leading to Exertion-Related Death: A Systematic Review

Lachelle D. Weeks, Allecia M. Wilson, Rakhi P. Naik, Yvonne A. Efebera, Mohammad Hassan Murad, Anjlee Mahajan, Patrick T. McGann, Madeleine Verhovsek, Angela C. Weyand, Ahmar Urooj Zaidi, Michael R DeBaun, Chancellor Donald, Roger A. Mitchell, Jr
Journal: Blood
Blood blood.2024026899.
https://doi.org/10.1182/blood.2024026899
Published: 2025
Journal Articles

A bulge uridine in the HIF2α IRE allows IRP1 but not IRP2 to selectively regulate HIF2α expression and ensuing EPO levels

De-Liang Zhang, Hayden Ollivierre, Chen-Feng Qi, Tracey A. Rouault
Journal: Blood
Blood (2025) 145 (5): 533–542.
https://doi.org/10.1182/blood.2024025246
Published: 2025
Includes: Supplemental data
Journal Articles

A phase 1 study of the amino acid modulator pegcrisantaspase and venetoclax for relapsed or refractory acute myeloid leukemia

Clinical Trials & Observations
Yuchen Liu, Dominique R. Bollino, Osman M. Bah, Erin T. Strovel, Tien V. Le, Jinoos Zarrabi, Sunita Philip, Rena G. Lapidus, Maria R. Baer, Sandrine Niyongere, Vu H. Duong, Christine C. Dougherty, Jan H. Beumer, Katherine D. Caprinolo, Farin Kamangar, Ashkan Emadi
Journal: Blood
Blood (2025) 145 (5): 486–496.
https://doi.org/10.1182/blood.2024024837
Published: 2025
Includes: Supplemental data
Journal Articles

Zanubrutinib, obinutuzumab, and venetoclax for first-line treatment of mantle cell lymphoma with a  TP53 mutation

Clinical Trials & Observations
Anita Kumar, Jacob Soumerai, Jeremy S. Abramson, Jeffrey A. Barnes, Philip Caron, Shalini Chhabra, Maria Chabowska, Ahmet Dogan, Lorenzo Falchi, Clare Grieve, J. Erika Haydu, Patrick Connor Johnson, Ashlee Joseph, Hailey E. Kelly, Alyssa Labarre, Jennifer Kimberly Lue, Rosalba Martignetti, Joanna Mi, Alison Moskowitz, Colette Owens, Sean Plummer, Madeline Puccio, Gilles Salles, Venkatraman Seshan, Elizabeth Simkins, Natalie Slupe, Honglei Zhang, Andrew D. Zelenetz
Journal: Blood
Blood (2025) 145 (5): 497–507.
https://doi.org/10.1182/blood.2024025563
Published: 2025
Includes: Supplemental data
Journal Articles

Soluble B-cell maturation antigen levels for disease monitoring in oligosecretory and nonsecretory relapsed multiple myeloma

Clinical Trials & Observations Brief Report
Daisuke Ikeda, Shuichi Aikawa, Chiho Misono, Mitsuaki Oura, Fuminari Fujii, Hajime Sakuma, Masanori Toho, Atsushi Uehara, Rikako Tabata, Kentaro Narita, Masami Takeuchi, Tomohisa Watari, Yoshihito Otsuka, Kosei Matsue
Journal: Blood
Blood (2025) 145 (5): 526–532.
https://doi.org/10.1182/blood.2024026028
Published: 2025
Includes: Supplemental data
Journal Articles

Genetic and clinical spectrum of SAMD9 and SAMD9L syndromes: from variant interpretation to patient management

Sushree S. Sahoo, Miriam Erlacher, Marcin W. Wlodarski
Journal: Blood
Blood (2025) 145 (5): 475–485.
https://doi.org/10.1182/blood.2022017717
Published: 2025
Includes: Supplemental data
Journal Articles

Imetelstat: a new addition to the therapeutic landscape of lower-risk MDS

Clinical Trials & Observations
Yasmin Abaza, Amy E. DeZern
Journal: Blood
Blood (2025) 145 (5): 469–474.
https://doi.org/10.1182/blood.2024025702
Published: 2025
Includes: Supplemental data
Journal Articles

Bivalent CD47 immunotoxin for targeted therapy of T-cell acute lymphoblastic leukemia

Jihong Ma, Zhaohui Wang, Danielle Mintzlaff, Huiping Zhang, Rashmi Ramakrishna, Eduardo Davila, Matthew T. Witkowski, M. Scott Lucia, Marc S. Schwartz, Elizabeth A. Pomfret, David W. Mathes, Zhirui Wang
Journal: Blood
Blood (2025) 145 (5): 508–519.
https://doi.org/10.1182/blood.2024025277
Published: 2025
Includes: Supplemental data
Journal Articles

Development of hyperdiploidy starts at an early age and takes a decade to complete

Brief Report
Mehmet K. Samur, Anil Aktas Samur, Parth Shah, Joseph S. Park, Mariateresa Fulciniti, Masood Shammas, Jill Corre, Kenneth C. Anderson, Giovanni Parmigiani, Hervé Avet-Loiseau, Nikhil C. Munshi
Journal: Blood
Blood (2025) 145 (5): 520–525.
https://doi.org/10.1182/blood.2024025250
Published: 2025
Includes: Supplemental data
Journal Articles

Beyond static measurements: dynamic frailty improves survival prediction in multiple myeloma

Clinical Trials & Observations
Febe Smits, Kaz Groen, Mark-David Levin, Claudia A. M. Stege, Roel van Kampen, Ellen van der Spek, Yavuz M. Bilgin, Noortje Thielen, Inger Nijhof, Inge Ludwig, Esther G. M. de Waal, Yorick Sandberg, Alain Kentos, Gert-Jan Timmers, Josien C. Regelink, Matthijs Westerman, Koen de Heer, Marie-Christiane Vekemans, Nazik Durdu-Rayman, Nicole C. H. P. de Graauw, Maarten R. Seefat, Niels W. C. J. van de Donk, Paula F. Ypma, Kazem Nasserinejad, Sonja Zweegman
Journal: Blood
Blood (2025) 145 (5): 543–546.
https://doi.org/10.1182/blood.2024025868
Published: 2025
Includes: Supplemental data
Journal Articles

Xu H, Cao Y, Yang X, Cai P, Kang L, Zhu X, Luo H, Lu L, Wei L, Bai X, Zhu Y, Zhao B-Q, Fan W. ADAMTS13 controls vascular remodeling by modifying VWF reactivity during stroke recovery. Blood . 2017;130(1):11-22.

Journal: Blood
Blood (2025) 145 (5): 550.
https://doi.org/10.1182/blood.2024028134
Published: 2025
Journal Articles

c-MYC stain as a potential minimal residual disease marker for acute myeloid leukemia with NPM1 mutation

Kirill A. Lyapichev, Amir Behdad
Journal: Blood
Blood (2025) 145 (5): 547.
https://doi.org/10.1182/blood.2024026942
Published: 2025
Journal Articles

How to prioritize between oxygen and iron

Esther G. Meyron-Holtz
Journal: Blood
Blood (2025) 145 (5): 465–467.
https://doi.org/10.1182/blood.2024026858
Published: 2025
Journal Articles

A 3-pronged attack on TP53 -mutated MCL

Clinical Trials & Observations
Christine E. Ryan, Ann S. LaCasce
Journal: Blood
Blood (2025) 145 (5): 458–460.
https://doi.org/10.1182/blood.2024027055
Published: 2025
Journal Articles

Quantifying MM disease burden by BCMA?

Kenneth H. Shain
Journal: Blood
Blood (2025) 145 (5): 464–465.
https://doi.org/10.1182/blood.2024027224
Published: 2025
Journal Articles

A novel therapy with a rational design for AML

Clinical Trials & Observations
Maria L. Amaya
Journal: Blood
Blood (2025) 145 (5): 457–458.
https://doi.org/10.1182/blood.2024027063
Published: 2025
Journal Articles

For how long has this problem been there?

Niccolò Bolli, Matteo Claudio da Vià
Journal: Blood
Blood (2025) 145 (5): 462–463.
https://doi.org/10.1182/blood.2024027361
Published: 2025
Journal Articles

Targeting CD47: many misses; hopeful for a hit

Lindsay Wilde, Margaret Kasner
Journal: Blood
Blood (2025) 145 (5): 460–462.
https://doi.org/10.1182/blood.2024027222
Published: 2025
Journal Articles

Woyach JA, Burbano GP, Ruppert AS, et al. Follow-up from the A041202 study shows continued efficacy of ibrutinib regimens for older adults with CLL. Blood . 2024;143(16):1616-1627.

Journal: Blood
Blood (2025) 145 (5): 548–549.
https://doi.org/10.1182/blood.2024027930
Published: 2025
Images
Regulation of the Hif2α subunit in the kidney. Translational regulation: Bi...

Regulation of the Hif2α subunit in the kidney. Translational regulation: Bi...

in How to prioritize between oxygen and iron > Blood
Published: 2025
Regulation of the Hif2α subunit in the kidney. Translational regulation: Binding of IRP1 to the 5’ RNA stem-loop of Hif2α inhibits its translation. The conformational change of IRP1 between its RNA-binding form (IRP1) and its cytosolic Aco1 form is an iron-sensing mechanism that functions only in th... More about this image found in Regulation of the Hif2α subunit in the kidney. Translational regulation: Bi...