Shown here is the ability of CELMoDs to reshape the BM T-cell compartment and increase the E:T ratio to enhance anti–BCMA-TCE efficacy in high disease burden. (A) Lack of activity of anti–BCMA-TCE when used alone in high disease burden. (B) Ability of CELMoDs to promote T-cell proliferation increasi... More about this image found in Shown here is the ability of CELMoDs to reshape the BM T-cell compartment a...

LEF1 gene alterations and their biological and clinical impact. (A) LEF1 gene alterations are found in 13% of the T-ALL cases, of which 14.3% are point mutations, 28.6% large deletions, and 57.1% focal deletions. Patients with LEF1 gene alterations display a higher prevalence of central nervous... More about this image found in LEF1 gene alterations and their biological and clinical impact. (A) LEF1 ...