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Journal Articles

Next-Generation JAK Inhibitors in the Treatment of Myeloproliferative Neoplasms

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Stefan N. Constantinescu, William Vainchenker, Christian Pecquet
Journal: Blood
Blood blood.2025028645.
https://doi.org/10.1182/blood.2025028645
Published: 2026
Journal Articles

Gastrin for the treatment of acute graft-versus-host disease of the stomach

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Jana Gawron, Marie Czech, Tamina Rückert, Verena Holzmüller, Grigor Andreev, Ann-Cathrin Burk, Alina Hartmann, Sangya Chatterjee, Geoffroy Andrieux, Franziska Elisabeth Marquard, Anna-Sophia Baur, Anna-Verena Stell, Máté Krausz, Lukas M Braun, Natascha Osswald, Wolfgang Melchinger, Tobias Wertheimer, Andrea Isabel Proano-Vasco, Kristina Maas-Bauer, Annette Schmitt-Graeff, Melanie Boerries, Natalie Köhler, Francis Ayuketang Ayuk, Christoph Schell, Michael Quante, Robert Zeiser
Journal: Blood
Blood blood.2025031080.
https://doi.org/10.1182/blood.2025031080
Published: 2026
Includes: Supplemental data
Journal Articles

Bispecific CAR-iNKT cells: beyond dual antigen targeting

Free
Federico Simonetta
Journal: Blood
Blood (2026) 147 (2): 100–101.
https://doi.org/10.1182/blood.2025030952
Published: 2026
Journal Articles

The telomeric puzzle in TP53 -mutant myeloid neoplasms

Free
Ing Soo Tiong, Lucy C. Fox
Journal: Blood
Blood (2026) 147 (2): 102–103.
https://doi.org/10.1182/blood.2025031124
Published: 2026
Journal Articles

Acute promyelocytic leukemia diagnosed on soft tissue biopsy: a rare extramedullary presentation

Free
William Fox Sharpe-Davidson, Yuen On Wan
Journal: Blood
Blood (2026) 147 (2): 215.
https://doi.org/10.1182/blood.2025031138
Published: 2026
Journal Articles

Introduction to a review series on marginal zone lymphoma: reclaiming the afterthought

Free
Philippe Armand
Journal: Blood
Blood (2026) 147 (2): 95.
https://doi.org/10.1182/blood.2025031752
Published: 2026
Journal Articles

Hematopoietic transplantation for PNP deficiency: it’s time

Free
Clinical Trials & Observations
Eyal Grunebaum
Journal: Blood
Blood (2026) 147 (2): 97–98.
https://doi.org/10.1182/blood.2025031143
Published: 2026
Journal Articles

Jagged2-Notch axis: keeping stem cells in asymmetric balance

Free
Nadia Carlesso
Journal: Blood
Blood (2026) 147 (2): 99–100.
https://doi.org/10.1182/blood.2025031619
Published: 2026
Journal Articles

The treatment of marginal zone lymphoma

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Juan Pablo Alderuccio, Ariela Noy
Journal: Blood
Blood (2026) 147 (2): 115–126.
https://doi.org/10.1182/blood.2024028269
Published: 2026
Journal Articles

Off-the-shelf dual CAR-iNKT cell immunotherapy eradicates medullary and leptomeningeal high-risk KMT2A -rearranged leukemia

Open Access
Hongwei Ren, Natalina Elliott, Bryan Lye, Mohammad Umer Sharif Shohan, Joe W. Cross, Lucy Field, Kanagaraju Ponnusamy, Siobhan Rice, Thomas Jackson, Ilia Leontari, Nouhad El Ouazzani, Rebecca Thomas, Sarah Inglott, Jack Bartram, Owen Smith, Jonathan Bond, Irene A. G. Roberts, Christina Halsey, Rachael Bashford-Rogers, Thomas A. Milne, Anindita Roy, Anastasios Karadimitris
Journal: Blood
Blood (2026) 147 (2): 180–196.
https://doi.org/10.1182/blood.2025029302
Published: 2026
Includes: Supplemental data
Journal Articles

Drug development in MZL: caring for the forgotten child

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Clinical Trials & Observations
Catherine Thieblemont, Sylvain Carras, Côme Bommier
Journal: Blood
Blood (2026) 147 (2): 127–137.
https://doi.org/10.1182/blood.2024028270
Published: 2026
Journal Articles

Telomere content and genomics of myeloid neoplasia by whole-genome sequencing

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Luca Guarnera, Adam Wahida, Carmelo Gurnari, Stephan Hutter, Sabine A. Stainczyk, Nakisha D. Williams, Arda Durmaz, Yasuo Kubota, Carlos Bravo-Perez, Naomi Kawashima, Mark Orland, Simona Pagliuca, Yimin Huang, Thomas LaFramboise, Valeria Visconte, Wencke Walter, Manja Meggendorfer, Wolfgang Kern, Frank Westermann, Lars Feuerbach, Torsten Haferlach, Jaroslaw P. Maciejewski
Journal: Blood
Blood (2026) 147 (2): 197–208.
https://doi.org/10.1182/blood.2025028644
Published: 2026
Includes: Supplemental data
Journal Articles

Hematopoietic stem cell transplantation for purine nucleoside phosphorylase deficiency: an EBMT-IEWP retrospective study

Open Access
Clinical Trials & Observations
Uli S. Herrmann, Matthias Felber, Austen Worth, Sule Haskologlu, Figen Dogu, Victor A. Lewis, Brigitte Strahm, Andreas Groll, Andrew R. Gennery, Fabian Hauck, Robert Wynn, Mary Coussons, Isabelle Meyts, Caroline Lindemans, Victoria Bordon, Robbert G. M. Bredius, Jörn-Sven Kühl, Mirjam Völler, Felix Zirngibl, Irina Zaidman, Alexandra Laberko, Ulrike Zeilhofer, Mathias Hauri-Hohl, Arjan Lankester, Aydan Ikinciogullari, Gregory M. T. Guilcher, Annette Hackenberg, Akif Yeşilipek, Graham Davies, Kanchan Rao, Michael Steven Hershfield, Suhag H. Parikh, Patrick Gilbert, Claudia Bettoni da Cunha Riehm, Michael H. Albert, Ansgar S. Schulz, Manfred Hönig, Bénédicte Neven, Tayfun Güngör
Journal: Blood
Blood (2026) 147 (2): 138–163.
https://doi.org/10.1182/blood.2025029640
Published: 2026
Includes: Supplemental data
Journal Articles

The biology of marginal zone lymphoma subtypes: challenge and relevance of classification

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Camille Laurent, Francesco Bertoni
Journal: Blood
Blood (2026) 147 (2): 105–114.
https://doi.org/10.1182/blood.2024028268
Published: 2026
Includes: Supplemental data
Journal Articles

A Notch trans- activation to cis -inhibition switch underlies hematopoietic stem cell aging

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Francesca Matteini, Roshana Thambyrajah, Sara Montserrat-Vazquez, Sascha Jung, Alba Ferrer-Perez, Patricia Herrero Molinero, Dina El Jaramany, Javier Lozano-Bartolomé, Eva Mejia-Ramirez, Jessica Gonzalez, Antonio Del Sol, Anna Bigas, Maria Carolina Florian
Journal: Blood
Blood (2026) 147 (2): 164–179.
https://doi.org/10.1182/blood.2024026505
Published: 2026
Includes: Multimedia, Supplemental data
Journal Articles

High-grade/large B-cell lymphoma-11q has a very good prognosis in children and young people without a predisposition

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Clinical Trials & Observations
Leila Ronceray, Minke H. W. Huibers, Katrin Reutter, Oussama Abla, Mara Andrés, Olga Balagué, Monika Csóka, Gil Gilad, Melanie M. Hagleitner, Daiki Hori, Lisa L. Hjalgrim, Janez Jazbec, Wolfram Klapper, Atsuko Nakazawa, Jaime Verdú-Amorós, Hannah von Mersi, Wilhelm Wössmann, Ana C. Xavier, Birgit Burkhardt, Itziar Salaverria, Andishe Attarbaschi
Journal: Blood
Blood (2026) 147 (2): 209–214.
https://doi.org/10.1182/blood.2025031086
Published: 2026
Includes: Supplemental data
Images
CAR-mediated and NKG2D-dependent targeting of KMT2Ar leukemia by bispecific CAR-iNKT cells.

CAR-mediated and NKG2D-dependent targeting of KMT2Ar leukemia by bispecific...

Free
in Bispecific CAR-iNKT cells: beyond dual antigen targeting > Blood
Published: 2026
CAR-mediated and NKG2D-dependent targeting of KMT2Ar leukemia by bispecific CAR-iNKT cells. More about this image found in CAR-mediated and NKG2D-dependent targeting of KMT2Ar leukemia by bispecific...
Images
“Cross-correction” of PNP deficiency in neuronal cells after allogeneic HCT. In the recipient’s PNP-deficient neurons, the absence of functional PNP enzyme prevents the phosphorolysis of substrates such as deoxyguanosine (dGuo) into hypoxanthine, leading to accumulation of dGTP. This disrupts the cell’s metabolism and leads to the cell’s apoptosis. Excess dGuo can also exit the cell through transmembrane NT. After transplantation, excess dGuo is taken up by the donor PNP-proficient blood cell across the blood-brain barrier, following the concentration gradient of dGuo, where it can be further metabolized, eventually leading to the restoration of purine metabolism in the neuron. dGTP, deoxyguanosine triphosphate; NT, nucleoside transporters. Figure created with BioRender.com. Grunebaum E. (2025) https://app.biorender.com/illustrations/689a34dde8409e308ef5ce82.

“Cross-correction” of PNP deficiency in neuronal cells after allogeneic HCT...

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in Hematopoietic transplantation for PNP deficiency: it’s time > Blood
Published: 2026
“Cross-correction” of PNP deficiency in neuronal cells after allogeneic HCT. In the recipient’s PNP-deficient neurons, the absence of functional PNP enzyme prevents the phosphorolysis of substrates such as deoxyguanosine (dGuo) into hypoxanthine, leading to accumulation of dGTP. This disrupts the ce... More about this image found in “Cross-correction” of PNP deficiency in neuronal cells after allogeneic HCT...
Images
Overview of contributors to TC. TL reflects the physical length of telomeric DNA repeats at the natural ends of chromosomes, which can be measured using methods such as TRF, flow-FISH, STELA, and long-read WGS. TC measures the total amount of telomeric DNA repeats and may include sources such as intrachromosomal telomeric insertions and neotelomeres formed at double-strand break sites. TC can be measured by methods like (qPCR), short-read WGS, and long-read WGS. Flow-FISH, flow cytometry–based fluorescence in situ hybridization; qPCR, quantitative polymerase chain reaction; STELA, single telomere length analysis; TRF, telomere restriction fragment. Figure created with BioRender. Tiong IS. (2025) https://BioRender.com/yg8q9ug.

Overview of contributors to TC. TL reflects the physical length of telomeri...

Free
in The telomeric puzzle in TP53 -mutant myeloid neoplasms > Blood
Published: 2026
Overview of contributors to TC. TL reflects the physical length of telomeric DNA repeats at the natural ends of chromosomes, which can be measured using methods such as TRF, flow-FISH, STELA, and long-read WGS. TC measures the total amount of telomeric DNA repeats and may include sources such as int... More about this image found in Overview of contributors to TC. TL reflects the physical length of telomeri...
Images
Outcome measures of the 72 patients with HGBCL-11q that were studied. (A) EFS and (B) OS of the 72 patients with HGBCL-11q. (C) EFS and (D) OS of the 60 patients with HGBCL-11q without a preexisting disorder compared with those of the 12 patients with HGBCL-11q with a preexisting disorder. pt, patient; SML, second malignancy.

Outcome measures of the 72 patients with HGBCL-11q that were studied. (A) ...

Available to Purchase
in High-grade/large B-cell lymphoma-11q has a very good prognosis in children and young people without a predisposition > Blood
Published: 2026
Figure 1. Outcome measures of the 72 patients with HGBCL-11q that were studied. (A) EFS and (B) OS of the 72 patients with HGBCL-11q. (C) EFS and (D) OS of the 60 patients with HGBCL-11q without a preexisting disorder compared with those of the 12 patients with HGBCL-11q with a preexisting disor... More about this image found in Outcome measures of the 72 patients with HGBCL-11q that were studied. (A) ...