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Issue Archive

Volume 131, Issue 9
March 1 2018
Issue Cover

Table of Contents

BLOOD COMMENTARIES

CLINICAL TRIALS AND OBSERVATIONS
MRD negativity as a surrogate for PFS in CLL?
Clinical Trials & Observations
Philip A. Thompson
View Articletitled, MRD negativity as a surrogate for PFS in CLL?
IMMUNOBIOLOGY AND IMMUNOTHERAPY
The elusive pathogenesis of Schnitzler syndrome
Giovanni Palladini,Giampaolo Merlini
View Articletitled, The elusive pathogenesis of Schnitzler syndrome
Lymphoid Neoplasia
R-spondin(g) to syndecan-1 in myeloma
Steven Grant
View Articletitled, R-spondin(g) to syndecan-1 in myeloma
Lymphoid Neoplasia
“Dar”-ing to target CD38 in T-ALL
Joseph Wynne,Wendy Stock
View Articletitled, “Dar”-ing to target CD38 in T-ALL
PLATELETS AND THROMBOPOIESIS
BEACHcombing for α-granules
Sidney W. Whiteheart
View Articletitled, BEACHcombing for α-granules
Red Cells, Iron, and Erythropoiesis
Unwinding the path from anemia to stroke
John C. Wood
View Articletitled, Unwinding the path from anemia to stroke
THROMBOSIS AND HEMOSTASIS
Hemophilia gene therapy is effective and safe
Michael Makris
View Articletitled, Hemophilia gene therapy is effective and safe

CLINICAL TRIALS AND OBSERVATIONS

A model for predicting effect of treatment on progression-free survival using MRD as a surrogate end point in CLL
Clinical Trials & Observations
Natalie Dimier,Paul Delmar,Carol Ward,Rodica Morariu-Zamfir,Günter Fingerle-Rowson,Jasmin Bahlo,Kirsten Fischer,Barbara Eichhorst,Valentin Goede,Jacques J. M. van Dongen,Matthias Ritgen,Sebastian Böttcher,Anton W. Langerak,Michael Kneba,Michael Hallek
View Articletitled, A model for predicting effect of treatment on progression-free survival using MRD as a surrogate end point in CLL
Supplemental data

HEMATOPOIESIS AND STEM CELLS

Hif-1α and Hif-2α regulate hemogenic endothelium and hematopoietic stem cell formation in zebrafish
Claudia Gerri,Michele Marass,Andrea Rossi,Didier Y. R. Stainier
View Articletitled, Hif-1α and Hif-2α regulate hemogenic endothelium and hematopoietic stem cell formation in zebrafish
Supplemental data

IMMUNOBIOLOGY AND IMMUNOTHERAPY

Molecular genetic investigation, clinical features, and response to treatment in 21 patients with Schnitzler syndrome
Dorota M. Rowczenio,Shelly Pathak,Juan I. Arostegui,Anna Mensa-Vilaro,Ebun Omoyinmi,Paul Brogan,Dan Lipsker,Thomas Scambler,Roger Owen,Hadija Trojer,Anna Baginska,Julian D. Gillmore,Ashutosh D. Wechalekar,Thirusha Lane,Rene Williams,Taryn Youngstein,Philip N. Hawkins,Sinisa Savic,Helen J. Lachmann
View Articletitled, Molecular genetic investigation, clinical features, and response to treatment in 21 patients with Schnitzler syndrome
Supplemental data

LYMPHOID NEOPLASIA

Syndecan-1 promotes Wnt/β-catenin signaling in multiple myeloma by presenting Wnts and R-spondins
Zemin Ren,Harmen van Andel,Wim de Lau,Robin B. Hartholt,Madelon M. Maurice,Hans Clevers,Marie José Kersten,Marcel Spaargaren,Steven T. Pals
View Articletitled, Syndecan-1 promotes Wnt/β-catenin signaling in multiple myeloma by presenting Wnts and R-spondins
Supplemental data
Preclinical efficacy of daratumumab in T-cell acute lymphoblastic leukemia
Brief Report
Karen L. Bride,Tiffaney L. Vincent,Soo-Yeon Im,Richard Aplenc,David M. Barrett,William L. Carroll,Robin Carson,Yunfeng Dai,Meenakshi Devidas,Kimberly P. Dunsmore,Tori Fuller,Tina Glisovic-Aplenc,Terzah M. Horton,Stephen P. Hunger,Mignon L. Loh,Shannon L. Maude,Elizabeth A. Raetz,Stuart S. Winter,Stephan A. Grupp,Michelle L. Hermiston,Brent L. Wood,David T. Teachey
View Articletitled, Preclinical efficacy of daratumumab in T-cell acute lymphoblastic leukemia
Supplemental data

PLATELETS AND THROMBOPOIESIS

Nbeal2 interacts with Dock7, Sec16a, and Vac14
Louisa Mayer,Maria Jasztal,Mercedes Pardo,Salvadora Aguera de Haro,Janine Collins,Tadbir K. Bariana,Peter A. Smethurst,Luigi Grassi,Romina Petersen,Paquita Nurden,Rémi Favier,Lu Yu,Stuart Meacham,William J. Astle,Jyoti Choudhary,Wyatt W. Yue,Willem H. Ouwehand,Jose A. Guerrero
View Articletitled, Nbeal2 interacts with Dock7, Sec16a, and Vac14
Supplemental data

RED CELLS, IRON, AND ERYTHROPOIESIS

Red cell exchange transfusions lower cerebral blood flow and oxygen extraction fraction in pediatric sickle cell anemia
Kristin P. Guilliams,Melanie E. Fields,Dustin K. Ragan,Cihat Eldeniz,Michael M. Binkley,Yasheng Chen,Liam S. Comiskey,Allan Doctor,Monica L. Hulbert,Joshua S. Shimony,Katie D. Vo,Robert C. McKinstry,Hongyu An,Jin-Moo Lee,Andria L. Ford
View Articletitled, Red cell exchange transfusions lower cerebral blood flow and oxygen extraction fraction in pediatric sickle cell anemia
Supplemental data

THROMBOSIS AND HEMOSTASIS

Gene therapy with adeno-associated virus vector 5–human factor IX in adults with hemophilia B
Clinical Trials & Observations
Wolfgang Miesbach,Karina Meijer,Michiel Coppens,Peter Kampmann,Robert Klamroth,Roger Schutgens,Marco Tangelder,Giancarlo Castaman,Joachim Schwäble,Halvard Bonig,Erhard Seifried,Federica Cattaneo,Christian Meyer,Frank W. G. Leebeek
View Articletitled, Gene therapy with adeno-associated virus vector 5–human factor IX in adults with hemophilia B
Supplemental data

LETTER TO BLOOD

Loss of Toll-like receptor 2 results in accelerated leukemogenesis in the NUP98-HOXD13 mouse model of MDS
Darlene A. Monlish,Sima T. Bhatt,Eric J. Duncavage,Zev J. Greenberg,John L. Keller,Molly P. Romine,Wei Yang,Peter D. Aplan,Matthew J. Walter,Laura G. Schuettpelz
View Articletitled, Loss of Toll-like receptor 2 results in accelerated leukemogenesis in the <em>NUP98-HOXD13</em> mouse model of MDS
Supplemental data

BLOOD WORK

Myelophthisic marrow involved by breast cancer and acute myeloid leukemia
William Shomali,Jason Gotlib
View Articletitled, Myelophthisic marrow involved by breast cancer and acute myeloid leukemia

ERRATUM

Lin RJ, Behera M, Diefenbach CS, Flowers CR. Role of anthracycline and comprehensive geriatric assessment for elderly patients with diffuse large B-cell lymphoma. Blood. 2017;130(20):2180-2185.
View Articletitled, Lin RJ, Behera M, Diefenbach CS, Flowers CR. Role of anthracycline and comprehensive geriatric assessment for elderly patients with diffuse large B-cell lymphoma. <em>Blood</em>. 2017;130(20):2180-2185.
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