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Volume 131, Issue 17
April 26 2018
Issue Cover

Table of Contents

BLOOD COMMENTARIES

PHAGOCYTES, GRANULOCYTES, AND MYELOPOIESIS
Myo1f is critical for neutrophil migration in vivo
Mauro M. Teixeira
View Articletitled, Myo1f is critical for neutrophil migration in vivo
CLINICAL TRIALS AND OBSERVATIONS
Ibrutinib: coming of age?
Clinical Trials & Observations
Jennifer R. Brown
View Articletitled, Ibrutinib: coming of age?
Lymphoid Neoplasia
Ibrutinib and fungus: an invasive concern
Kerry Rogers
View Articletitled, Ibrutinib and fungus: an invasive concern
Red Cells, Iron, and Erythropoiesis
A chance to cut (the genome) is a chance to cure
Kara E. Montbleau,Vijay G. Sankaran
View Articletitled, A chance to cut (the genome) is a chance to cure

PLENARY PAPER

PHAGOCYTES, GRANULOCYTES, AND MYELOPOIESIS
Myosin 1f is specifically required for neutrophil migration in 3D environments during acute inflammation
Melanie Salvermoser,Robert Pick,Ludwig T. Weckbach,Annette Zehrer,Phillip Löhr,Maik Drechsler,Markus Sperandio,Oliver Soehnlein,Barbara Walzog
View Articletitled, Myosin 1f is specifically required for neutrophil migration in 3D environments during acute inflammation
Supplemental data

BLOOD SPOTLIGHT

The search for new antithrombotic mechanisms and therapies that may spare hemostasis
Edward F. Plow,Yunmei Wang,Daniel I. Simon
View Articletitled, The search for new antithrombotic mechanisms and therapies that may spare hemostasis

REVIEW ARTICLE

Coagulation factor XII in thrombosis and inflammation
Coen Maas,Thomas Renné
View Articletitled, Coagulation factor XII in thrombosis and inflammation

CLINICAL TRIALS AND OBSERVATIONS

Single-agent ibrutinib in treatment-naïve and relapsed/refractory chronic lymphocytic leukemia: a 5-year experience
Clinical Trials & Observations
Susan O’Brien,Richard R. Furman,Steven Coutre,Ian W. Flinn,Jan A. Burger,Kristie Blum,Jeff Sharman,William Wierda,Jeffrey Jones,Weiqiang Zhao,Nyla A. Heerema,Amy J. Johnson,Ying Luan,Danelle F. James,Alvina D. Chu,John C. Byrd
View Articletitled, Single-agent ibrutinib in treatment-naïve and relapsed/refractory chronic lymphocytic leukemia: a 5-year experience
Supplemental data

HEMATOPOIESIS AND STEM CELLS

Epigenetic silencing of miR-125b is required for normal B-cell development
Guideng Li,Alex Yick-Lun So,Reeshelle Sookram,Stephanie Wong,Jessica K. Wang,Yong Ouyang,Peng He,Yapeng Su,Rafael Casellas,David Baltimore
View Articletitled, Epigenetic silencing of miR-125b is required for normal B-cell development
Supplemental data

LYMPHOID NEOPLASIA

Alterations in the Rho pathway contribute to Epstein-Barr virus–induced lymphomagenesis in immunosuppressed environments
Sung-Yup Cho,Chang Ohk Sung,Jeesoo Chae,Jieun Lee,Deukchae Na,Wonyoung Kang,Jinjoo Kang,Seoyeon Min,Ahra Lee,Eunhye Kwak,Jooyoung Kim,Boram Choi,Hyunsoo Kim,Jeffrey H. Chuang,Hyo-Kyung Pak,Chan-Sik Park,Sanghui Park,Young Hyeh Ko,Dakeun Lee,Jin Roh,Min-Sun Cho,Seongyeol Park,Young Seok Ju,Yun-Suhk Suh,Seong-Ho Kong,Hyuk-Joon Lee,James Keck,Jacques Banchereau,Edison T. Liu,Woo-Ho Kim,Hansoo Park,Han-Kwang Yang,Jong-Il Kim,Charles Lee
View Articletitled, Alterations in the Rho pathway contribute to Epstein-Barr virus–induced lymphomagenesis in immunosuppressed environments
Supplemental data
Low catalase expression confers redox hypersensitivity and identifies an indolent clinical behavior in CLL
Chiara Cavallini,Roberto Chignola,Ilaria Dando,Omar Perbellini,Elda Mimiola,Ornella Lovato,Carlo Laudanna,Giovanni Pizzolo,Massimo Donadelli,Maria Teresa Scupoli
View Articletitled, Low <em>catalase</em> expression confers redox hypersensitivity and identifies an indolent clinical behavior in CLL
Supplemental data
Early-onset invasive aspergillosis and other fungal infections in patients treated with ibrutinib
Clinical Trials & Observations Brief Report
David Ghez,Anne Calleja,Caroline Protin,Marine Baron,Marie-Pierre Ledoux,Gandhi Damaj,Mathieu Dupont,Brigitte Dreyfus,Emmanuelle Ferrant,Charles Herbaux,Kamel Laribi,Ronan Le Calloch,Marion Malphettes,Franciane Paul,Laetitia Souchet,Malgorzata Truchan-Graczyk,Karen Delavigne,Caroline Dartigeas,Loïc Ysebaert,on behalf on the French Innovative Leukemia Organization (FILO) CLL group,on behalf on the French Innovative Leukemia Organization (FILO) CLL group,on behalf on the French Innovative Leukemia Organization (FILO) CLL group,on behalf on the French Innovative Leukemia Organization (FILO) CLL group,on behalf on the French Innovative Leukemia Organization (FILO) CLL group,on behalf on the French Innovative Leukemia Organization (FILO) CLL group,on behalf on the French Innovative Leukemia Organization (FILO) CLL group,on behalf on the French Innovative Leukemia Organization (FILO) CLL group,on behalf on the French Innovative Leukemia Organization (FILO) CLL group,on behalf on the French Innovative Leukemia Organization (FILO) CLL group,on behalf on the French Innovative Leukemia Organization (FILO) CLL group,on behalf on the French Innovative Leukemia Organization (FILO) CLL group,on behalf on the French Innovative Leukemia Organization (FILO) CLL group,on behalf on the French Innovative Leukemia Organization (FILO) CLL group,on behalf on the French Innovative Leukemia Organization (FILO) CLL group,on behalf on the French Innovative Leukemia Organization (FILO) CLL group,on behalf on the French Innovative Leukemia Organization (FILO) CLL group,on behalf on the French Innovative Leukemia Organization (FILO) CLL group,on behalf on the French Innovative Leukemia Organization (FILO) CLL group
View Articletitled, Early-onset invasive aspergillosis and other fungal infections in patients treated with ibrutinib
Supplemental data

RED CELLS, IRON, AND ERYTHROPOIESIS

Induction of fetal hemoglobin synthesis by CRISPR/Cas9-mediated editing of the human β-globin locus
Chiara Antoniani,Vasco Meneghini,Annalisa Lattanzi,Tristan Felix,Oriana Romano,Elisa Magrin,Leslie Weber,Giulia Pavani,Sara El Hoss,Ryo Kurita,Yukio Nakamura,Thomas J. Cradick,Ante S. Lundberg,Matthew Porteus,Mario Amendola,Wassim El Nemer,Marina Cavazzana,Fulvio Mavilio,Annarita Miccio
View Articletitled, Induction of fetal hemoglobin synthesis by CRISPR/Cas9-mediated editing of the human β-globin locus
Supplemental data

TRANSPLANTATION

MicroRNA-17-92 is required for T-cell and B-cell pathogenicity in chronic graft-versus-host disease in mice
Yongxia Wu,Steven Schutt,Katelyn Paz,Mengmeng Zhang,Ryan P. Flynn,David Bastian,M. Hanief Sofi,Hung Nguyen,Min Dai,Chen Liu,Ying-Jun Chang,Bruce R. Blazar,Xue-Zhong Yu
View Articletitled, MicroRNA-17-92 is required for T-cell and B-cell pathogenicity in chronic graft-versus-host disease in mice
Supplemental data

LETTERS TO BLOOD

Risk of hepatitis B virus reactivation in patients treated with ibrutinib
Clinical Trials & Observations
Sarah P. Hammond,Kaiwen Chen,Alisha Pandit,Matthew S. Davids,Nicolas C. Issa,Francisco M. Marty
View Articletitled, Risk of hepatitis B virus reactivation in patients treated with ibrutinib
Transplant outcome for patients with acquired aplastic anemia over the age of 40: has the outcome improved?
Clinical Trials & Observations
Sabrina Giammarco,Régis Peffault de Latour,Simona Sica,Carlo Dufour,Gerard Socie,Jakob Passweg,Nicolaus Kröger,Eefke Petersen,Maria Teresa Van Lint,Rosi Oneto,Alessio Signori,Andrea Bacigalupo,for the European Group for Blood and Marrow Transplantation Severe Aplastic Anemia Working Party,for the European Group for Blood and Marrow Transplantation Severe Aplastic Anemia Working Party,for the European Group for Blood and Marrow Transplantation Severe Aplastic Anemia Working Party,for the European Group for Blood and Marrow Transplantation Severe Aplastic Anemia Working Party,for the European Group for Blood and Marrow Transplantation Severe Aplastic Anemia Working Party,for the European Group for Blood and Marrow Transplantation Severe Aplastic Anemia Working Party,for the European Group for Blood and Marrow Transplantation Severe Aplastic Anemia Working Party,for the European Group for Blood and Marrow Transplantation Severe Aplastic Anemia Working Party,for the European Group for Blood and Marrow Transplantation Severe Aplastic Anemia Working Party,for the European Group for Blood and Marrow Transplantation Severe Aplastic Anemia Working Party,for the European Group for Blood and Marrow Transplantation Severe Aplastic Anemia Working Party,for the European Group for Blood and Marrow Transplantation Severe Aplastic Anemia Working Party
View Articletitled, Transplant outcome for patients with acquired aplastic anemia over the age of 40: has the outcome improved?

BLOOD WORK

EBV+ mucocutaneous ulcer: a new entity of WHO 2017
Colin McCormack,Qin Huang
View Articletitled, EBV<sup>+</sup> mucocutaneous ulcer: a new entity of WHO 2017
Plasma cell leukemia presenting as “lymphocytosis”
Shaoying Li,Jie Xu
View Articletitled, Plasma cell leukemia presenting as “lymphocytosis”
All Issues

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