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Issue Archive

Volume 114, Issue 23
November 26 2009
Issue Cover

Table of Contents

INSIDE BLOOD

PLATELETS & THROMBOPOIESIS
The proof is in the crystal
José A. López,Adam Munday
View Articletitled, The proof is in the crystal
CLINICAL TRIALS
Childhood ITP: knowing when to worry?
Michele P. Lambert
View Articletitled, Childhood ITP: knowing when to worry?
GENE THERAPY
Arming CTLs against immunosuppressors
Patrizia Comoli
View Articletitled, Arming CTLs against immunosuppressors

REVIEW ARTICLES

Chronic lymphocytic leukemia: interplay between noncoding RNAs and protein-coding genes
George A. Calin,Carlo M. Croce
View Articletitled, Chronic lymphocytic leukemia: interplay between noncoding RNAs and protein-coding genes

CLINICAL TRIALS AND OBSERVATIONS

Primary radiotherapy showed favorable outcome in treating extranodal nasal-type NK/T-cell lymphoma in children and adolescents
Clinical Trials & Observations
Zhao-Yang Wang,Ye-Xiong Li,Wei-Hu Wang,Jing Jin,Hua Wang,Yong-Wen Song,Qing-Feng Liu,Shu-Lian Wang,Yue-Ping Liu,Shu-Nan Qi,Hui Fang,Xin-Fan Liu,Zi-Hao Yu
View Articletitled, Primary radiotherapy showed favorable outcome in treating extranodal nasal-type NK/T-cell lymphoma in children and adolescents
Intracranial hemorrhage (ICH) in children with immune thrombocytopenia (ITP): study of 40 cases
Clinical Trials & Observations
Bethan Psaila,Aleksandra Petrovic,Lemke K. Page,Jill Menell,Matthew Schonholz,James B. Bussel
View Articletitled, Intracranial hemorrhage (ICH) in children with immune thrombocytopenia (ITP): study of 40 cases

GENE THERAPY

Generation of Epstein-Barr virus–specific cytotoxic T lymphocytes resistant to the immunosuppressive drug tacrolimus (FK506)
Biagio De Angelis,Gianpietro Dotti,Concetta Quintarelli,Leslie E. Huye,Lan Zhang,Ming Zhang,Fabrizio Pane,Helen E. Heslop,Malcolm K. Brenner,Cliona M. Rooney,Barbara Savoldo
View Articletitled, Generation of Epstein-Barr virus–specific cytotoxic T lymphocytes resistant to the immunosuppressive drug tacrolimus (FK506)
Supplemental data
Generation of EBV-specific cytotoxic T cells that are resistant to calcineurin inhibitors for the treatment of posttransplantation lymphoproliferative disease
Jennifer Brewin,Christoph Mancao,Karin Straathof,Helen Karlsson,Sujith Samarasinghe,Persis J. Amrolia,Martin Pule
View Articletitled, Generation of EBV-specific cytotoxic T cells that are resistant to calcineurin inhibitors for the treatment of posttransplantation lymphoproliferative disease
Supplemental data

HEMATOPOIESIS AND STEM CELLS

Systematic in vivo structure-function analysis of p300 in hematopoiesis
Erin A. Kimbrel,Madeleine E. Lemieux,Xiaobo Xia,Tina N. Davis,Vivienne I. Rebel,Andrew L. Kung
View Articletitled, Systematic in vivo structure-function analysis of p300 in hematopoiesis
Supplemental data
Sox7-sustained expression alters the balance between proliferation and differentiation of hematopoietic progenitors at the onset of blood specification
Arnaud Gandillet,Alicia G. Serrano,Stella Pearson,Michael Lie-A-Ling,Georges Lacaud,Valerie Kouskoff
View Articletitled, Sox7-sustained expression alters the balance between proliferation and differentiation of hematopoietic progenitors at the onset of blood specification
Supplemental data

IMMUNOBIOLOGY

Functionally distinct subsets of human NK cells and monocyte/DC-like cells identified by coexpression of CD56, CD7, and CD4
Jeffrey M. Milush,Brian R. Long,Jennifer E. Snyder-Cappione,Amedeo J. Cappione, III,Vanessa A. York,Lishomwa C. Ndhlovu,Lewis L. Lanier,Jakob Michaëlsson,Douglas F. Nixon
View Articletitled, Functionally distinct subsets of human NK cells and monocyte/DC-like cells identified by coexpression of CD56, CD7, and CD4

LYMPHOID NEOPLASIA

In vivo intraclonal and interclonal kinetic heterogeneity in B-cell chronic lymphocytic leukemia
Carlo Calissano,Rajendra N. Damle,Gregory Hayes,Elizabeth J. Murphy,Marc K. Hellerstein,Carol Moreno,Cristina Sison,Matthew S. Kaufman,Jonathan E. Kolitz,Steven L. Allen,Kanti R. Rai,Nicholas Chiorazzi
View Articletitled, In vivo intraclonal and interclonal kinetic heterogeneity in B-cell chronic lymphocytic leukemia
Supplemental data
Genetic variation in CXCR4 and risk of chronic lymphocytic leukemia
Brief Report
Dalemari Crowther-Swanepoel,Mobshra Qureshi,Martin J. S. Dyer,Estella Matutes,Claire Dearden,Daniel Catovsky,Richard S. Houlston
View Articletitled, Genetic variation in <em>CXCR4</em> and risk of chronic lymphocytic leukemia
Supplemental data

MYELOID NEOPLASIA

Relationship of differential gene expression profiles in CD34+ myelodysplastic syndrome marrow cells to disease subtype and progression
Kunju Sridhar,Douglas T. Ross,Robert Tibshirani,Atul J. Butte,Peter L. Greenberg
View Articletitled, Relationship of differential gene expression profiles in CD34<sup>+</sup> myelodysplastic syndrome marrow cells to disease subtype and progression
Supplemental data
Expression profiling of a hemopoietic cell survival transcriptome implicates osteopontin as a functional prognostic factor in AML
Jason A. Powell,Daniel Thomas,Emma F. Barry,Chung H. Kok,Barbara J. McClure,Anna Tsykin,L. Bik To,Anna Brown,Ian D. Lewis,Kirsten Herbert,Gregory J. Goodall,Terence P. Speed,Norio Asou,Bindya Jacob,Motomi Osato,David N. Haylock,Susan K. Nilsson,Richard J. D'Andrea,Angel F. Lopez,Mark A. Guthridge
View Articletitled, Expression profiling of a hemopoietic cell survival transcriptome implicates osteopontin as a functional prognostic factor in AML
Supplemental data

PHAGOCYTES, GRANULOCYTES, AND MYELOPOIESIS

Neutrophil-specific deletion of Syk kinase results in reduced host defense to bacterial infection
Jessica A. Van Ziffle,Clifford A. Lowell
View Articletitled, Neutrophil-specific deletion of Syk kinase results in reduced host defense to bacterial infection
Supplemental data

PLATELETS AND THROMBOPOIESIS

Glycoprotein Ibα inhibitor complex structure reveals a combined steric and allosteric mechanism of von Willebrand factor antagonism
Brief Report
Paul A. McEwan,Robert K. Andrews,Jonas Emsley
View Articletitled, Glycoprotein Ibα inhibitor complex structure reveals a combined steric and allosteric mechanism of von Willebrand factor antagonism
Supplemental data

THROMBOSIS AND HEMOSTASIS

Contributions of extravascular and intravascular cells to fibrin network formation, structure, and stability
Robert A. Campbell,Katherine A. Overmyer,Craig H. Selzman,Brett C. Sheridan,Alisa S. Wolberg
View Articletitled, Contributions of extravascular and intravascular cells to fibrin network formation, structure, and stability
Supplemental data

VASCULAR BIOLOGY

Role of tyrosine phosphatase SHP-1 in the mechanism of endorepellin angiostatic activity
Alexander Nyström,Zabeena P. Shaik,Donald Gullberg,Thomas Krieg,Beate Eckes,Roy Zent,Ambra Pozzi,Renato V. Iozzo
View Articletitled, Role of tyrosine phosphatase SHP-1 in the mechanism of endorepellin angiostatic activity
Supplemental data

CORRESPONDENCE

Insufficient evidence to suggest less stringent therapy in hemophilia B?
Ingrid E. M. den Uijl,Goris Roosendaal,Kathelijn Fischer
View Articletitled, Insufficient evidence to suggest less stringent therapy in hemophilia B?
Response: Comparing joint arthroplasties in severe hemophilia A with severe hemophilia B
Giuseppe Tagariello,Alfonso Iorio,Pier M. Mannucci
View Articletitled, Response: Comparing joint arthroplasties in severe hemophilia A with severe hemophilia B
Delayed but functional neutrophil extracellular trap formation in neonates
Veronica Marcos,Claudia Nussbaum,Ljubomir Vitkov,Andreas Hector,Eva-Maria Wiedenbauer,Dirk Roos,Taco Kuijpers,Wolf Dietrich Krautgartner,Orsolya Genzel-Boroviczény,Markus Sperandio,Dominik Hartl
View Articletitled, Delayed but functional neutrophil extracellular trap formation in neonates
Response: Gestational age as a factor in neutrophil extracellular trap formation
Christian Con Yost,Guy A. Zimmerman
View Articletitled, Response: Gestational age as a factor in neutrophil extracellular trap formation
All Issues

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