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Journal Articles

Validation of the EuroClonality-NGS DNA capture panel as an integrated genomic tool for lymphoproliferative disorders

James Peter Stewart, Jana Gazdova, Nikos Darzentas, Dörte Wren, Paula Proszek, Grazia Fazio, Simona Songia, Miguel Alcoceba, Maria Eugenia Sarasquete, Patrick Villarese, Michèle Y. van der Klift, Kim C. Heezen, Neil McCafferty, Karol Pal, Mark Catherwood, Chang Sik Kim, Shambhavi Srivastava, Leonie I. Kroeze, Elizabeth Hodges, Kostas Stamatopoulos, Wolfram Klapper, Elisa Genuardi, Simone Ferrero, Michiel van den Brand, Giovanni Cazzaniga, Frederic Davi, Lesley-Ann Sutton, Ramon Garcia-Sanz, Patricia J. T. A. Groenen, Elizabeth A. Macintyre, Monika Brüggemann, Christiane Pott, Anton W. Langerak, David Gonzalez, on behalf of the EuroClonality-NGS Working Group
Journal: Blood Advances
Blood Adv (2021) 5 (16): 3188–3198.
https://doi.org/10.1182/bloodadvances.2020004056
Published: 2021
Includes: Supplemental data
Journal Articles

Additional chromosomal abnormalities at chronic myeloid leukemia diagnosis predict an increased risk of progression

Clinical Trials & Observations
Richard E. Clark, Jane F. Apperley, Mhairi Copland, Silvia Cicconi
Journal: Blood Advances
Blood Adv (2021) 5 (4): 1102–1109.
https://doi.org/10.1182/bloodadvances.2020003570
Published: 2021
Includes: Supplemental data
Journal Articles

Challenging conventional karyotyping by next-generation karyotyping in 281 intensively treated patients with AML

Sylvain Mareschal, Anna Palau, Johan Lindberg, Philippe Ruminy, Christer Nilsson, Sofia Bengtzén, Marie Engvall, Anna Eriksson, Anne Neddermeyer, Vinciane Marchand, Monika Jansson, My Björklund, Fabrice Jardin, Mattias Rantalainen, Andreas Lennartsson, Lucia Cavelier, Henrik Grönberg, Sören Lehmann
Journal: Blood Advances
Blood Adv (2021) 5 (4): 1003–1016.
https://doi.org/10.1182/bloodadvances.2020002517
Published: 2021
Includes: Supplemental data
Journal Articles

Molecular background delineates outcome of double protein expressor diffuse large B-cell lymphoma

Clinical Trials & Observations
Leo Meriranta, Annika Pasanen, Amjad Alkodsi, Jari Haukka, Marja-Liisa Karjalainen-Lindsberg, Sirpa Leppä
Journal: Blood Advances
Blood Adv (2020) 4 (15): 3742–3753.
https://doi.org/10.1182/bloodadvances.2020001727
Published: 2020
Includes: Supplemental data
Journal Articles

Clinical characteristics and treatment outcomes of newly diagnosed multiple myeloma with chromosome 1q abnormalities

Clinical Trials & Observations
Nadine Abdallah, Patricia Greipp, Prashant Kapoor, Morie A. Gertz, Angela Dispenzieri, Linda B. Baughn, Martha Q. Lacy, Suzanne R. Hayman, Francis K. Buadi, David Dingli, Ronald S. Go, Yi L. Hwa, Amie Fonder, Miriam Hobbs, Yi Lin, Nelson Leung, Taxiarchis Kourelis, Rahma Warsame, Mustaqeem Siddiqui, John Lust, Robert A. Kyle, Leif Bergsagel, Rhett Ketterling, S. Vincent Rajkumar, Shaji K. Kumar
Journal: Blood Advances
Blood Adv (2020) 4 (15): 3509–3519.
https://doi.org/10.1182/bloodadvances.2020002218
Published: 2020
Includes: Supplemental data
Journal Articles

Extra copies of MYC, BCL2, and BCL6 and outcome in patients with diffuse large B-cell lymphoma

Clinical Trials & Observations
David Sermer, Sabela Bobillo, Ahmet Dogan, Yanming Zhang, Venkatraman Seshan, Jessica A. Lavery, Connie Batlevi, Philip Caron, Audrey Hamilton, Paul Hamlin, Steven Horwitz, Erel Joffe, Anita Kumar, Matthew Matasar, Ariela Noy, Colette Owens, Alison Moskowitz, M. Lia Palomba, David Straus, Gottfried von Keudell, Ildefonso Rodriguez-Rivera, Lorenzo Falchi, Andrew Zelenetz, Joachim Yahalom, Anas Younes
Journal: Blood Advances
Blood Adv (2020) 4 (14): 3382–3390.
https://doi.org/10.1182/bloodadvances.2020001551
Published: 2020
Includes: Supplemental data
Journal Articles

Lenalidomide/rituximab induces high molecular response in untreated follicular lymphoma: LYSA ancillary RELEVANCE study

Clinical Trials & Observations
Marie-Helene Delfau-Larue, Marie-Laure Boulland, Asma Beldi-Ferchiou, Pierre Feugier, Hervé Maisonneuve, Rene-Olivier Casasnovas, François Lemonnier, Gian Matteo Pica, Roch Houot, Loic Ysebaert, Hervé Tilly, Jean-Claude Eisenmann, Steven Le Gouill, Vincent Ribrag, Pascal Godmer, Sylvie Glaisner, Guillaume Cartron, Luc Xerri, Gilles André Salles, Thierry Fest, Franck Morschhauser
Journal: Blood Advances
Blood Adv (2020) 4 (14): 3217–3223.
https://doi.org/10.1182/bloodadvances.2020001955
Published: 2020
Includes: Supplemental data
Journal Articles

Molecular pathogenesis of progression to myeloid leukemia from TET-insufficient status

Raksha Shrestha, Mamiko Sakata-Yanagimoto, Koichiro Maie, Motohiko Oshima, Masatomo Ishihara, Yasuhito Suehara, Kota Fukumoto, Yaeko Nakajima-Takagi, Hirotaka Matsui, Takayasu Kato, Hideharu Muto, Tatsuhiro Sakamoto, Manabu Kusakabe, Yasuhito Nannya, Hideki Makishima, Hiroo Ueno, Ryunosuke Saiki, Seishi Ogawa, Kenichi Chiba, Yuichi Shiraishi, Satoru Miyano, Enguerran Mouly, Olivier A. Bernard, Toshiya Inaba, Haruhiko Koseki, Atsushi Iwama, Shigeru Chiba
Journal: Blood Advances
Blood Adv (2020) 4 (5): 845–854.
https://doi.org/10.1182/bloodadvances.2019001324
Published: 2020
Includes: Supplemental data
Journal Articles

Clinical diagnostics and treatment strategies for Philadelphia chromosome–like acute lymphoblastic leukemia

Clinical Trials & Observations
Richard C. Harvey, Sarah K. Tasian
Journal: Blood Advances
Blood Adv (2020) 4 (1): 218–228.
https://doi.org/10.1182/bloodadvances.2019000163
Published: 2020
Journal Articles

High-efficiency CRISPR induction of t(9;11) chromosomal translocations and acute leukemias in human blood stem cells

Johan Jeong, Astraea Jager, Pablo Domizi, Mara Pavel-Dinu, Linda Gojenola, Masayuki Iwasaki, Michael C. Wei, Feng Pan, James L. Zehnder, Matthew H. Porteus, Kara L. Davis, Michael L. Cleary
Journal: Blood Advances
Blood Adv (2019) 3 (19): 2825–2835.
https://doi.org/10.1182/bloodadvances.2019000450
Published: 2019
Includes: Supplemental data
Journal Articles

Predisposition to childhood acute lymphoblastic leukemia caused by a constitutional translocation disrupting ETV6

Tekla Järviaho, Benedicte Bang, Vasilios Zachariadis, Fulya Taylan, Jukka Moilanen, Merja Möttönen, C. I. Edvard Smith, Arja Harila-Saari, Riitta Niinimäki, Ann Nordgren
Journal: Blood Advances
Blood Adv (2019) 3 (18): 2722–2731.
https://doi.org/10.1182/bloodadvances.2018028795
Published: 2019
Includes: Supplemental data
Journal Articles

Impact of acquired del(17p) in multiple myeloma

Clinical Trials & Observations
Arjun Lakshman, Utkarsh Painuly, S. Vincent Rajkumar, Rhett P. Ketterling, Prashant Kapoor, Patricia T. Greipp, Angela Dispenzieri, Morie A. Gertz, Francis K. Buadi, Martha Q. Lacy, David Dingli, Amie L. Fonder, Suzanne R. Hayman, Miriam A. Hobbs, Wilson I. Gonsalves, Yi Lisa Hwa, Nelson Leung, Ronald S. Go, Yi Lin, Taxiarchis V. Kourelis, Rahma Warsame, John A. Lust, Stephen J. Russell, Steven R. Zeldenrust, Robert A. Kyle, Shaji K. Kumar
Journal: Blood Advances
Blood Adv (2019) 3 (13): 1930–1938.
https://doi.org/10.1182/bloodadvances.2018028530
Published: 2019
Includes: Supplemental data
Journal Articles

Myeloid translocation gene CBFA2T3 directs a relapse gene program and determines patient-specific outcomes in AML

Nickolas Steinauer, Chun Guo, Chunfa Huang, Madeline Wong, Yifan Tu, Carl E. Freter, Jinsong Zhang
Journal: Blood Advances
Blood Adv (2019) 3 (9): 1379–1393.
https://doi.org/10.1182/bloodadvances.2018028514
Published: 2019
Includes: Supplemental data
Journal Articles

High-resolution architecture and partner genes of MYC rearrangements in lymphoma with DLBCL morphology

Lauren C. Chong, Susana Ben-Neriah, Graham W. Slack, Ciara Freeman, Daisuke Ennishi, Anja Mottok, Brett Collinge, Pau Abrisqueta, Pedro Farinha, Merrill Boyle, Barbara Meissner, Robert Kridel, Alina S. Gerrie, Diego Villa, Kerry J. Savage, Laurie H. Sehn, Reiner Siebert, Ryan D. Morin, Randy D. Gascoyne, Marco A. Marra, Joseph M. Connors, Andrew J. Mungall, Christian Steidl, David W. Scott
Journal: Blood Advances
Blood Adv (2018) 2 (20): 2755–2765.
https://doi.org/10.1182/bloodadvances.2018023572
Published: 2018
Includes: Supplemental data
Journal Articles

Cytogenetic intraclonal heterogeneity of plasma cell dyscrasia in AL amyloidosis as compared with multiple myeloma

Tilmann Bochtler, Maximilian Merz, Thomas Hielscher, Martin Granzow, Korbinian Hoffmann, Alwin Krämer, Marc-Steffen Raab, Jens Hillengass, Anja Seckinger, Christoph Kimmich, Tobias Dittrich, Carsten Müller-Tidow, Dirk Hose, Hartmut Goldschmidt, Ute Hegenbart, Anna Jauch, Stefan O. Schönland
Journal: Blood Advances
Blood Adv (2018) 2 (20): 2607–2618.
https://doi.org/10.1182/bloodadvances.2018023200
Published: 2018
Includes: Supplemental data
Journal Articles

MLL leukemia induction by t(9;11) chromosomal translocation in human hematopoietic stem cells using genome editing

Corina Schneidawind, Johan Jeong, Dominik Schneidawind, In-Suk Kim, Jesús Duque-Afonso, Stephen Hon Kit Wong, Masayuki Iwasaki, Erin H. Breese, James L. Zehnder, Matthew Porteus, Michael L. Cleary
Journal: Blood Advances
Blood Adv (2018) 2 (8): 832–845.
https://doi.org/10.1182/bloodadvances.2017013748
Published: 2018
Includes: Supplemental data
Journal Articles

C/EBPα overrides epigenetic reprogramming by oncogenic transcription factors in acute myeloid leukemia

Justin Loke, Paulynn Suyin Chin, Peter Keane, Anna Pickin, Salam A. Assi, Anetta Ptasinska, Maria Rosaria Imperato, Peter N. Cockerill, Constanze Bonifer
Journal: Blood Advances
Blood Adv (2018) 2 (3): 271–284.
https://doi.org/10.1182/bloodadvances.2017012781
Published: 2018
Includes: Supplemental data
Journal Articles

Sphingomyelin encrypts tissue factor: ATP-induced activation of A-SMase leads to tissue factor decryption and microvesicle shedding

Jue Wang, Usha R. Pendurthi, L. Vijaya Mohan Rao
Journal: Blood Advances
Blood Adv (2017) 1 (13): 849–862.
https://doi.org/10.1182/bloodadvances.2016003947
Published: 2017
Includes: Supplemental data