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Journal Articles

IAP and HDAC inhibitors interact synergistically in myeloma cells through noncanonical NF-κB– and caspase-8–dependent mechanisms

Liang Zhou, Yu Zhang, Mark B. Meads, Yun Dai, Yanxia Ning, Xiaoyan Hu, Lin Li, Kanika Sharma, Jewel Nkwocha, Rebecca Parker, Danny Bui, Jacquelyn McCarter, Lora Kramer, Cullen Purcell, Praneeth R. Sudalagunta, Rafael R. Canevarolo, Maria D. Coelho Siqueira Silva, Gabriel De Avila, Raghunandan Reddy Alugubelli, Ariosto S. Silva, Maciej Kmeiciak, Andrea Ferreira-Gonzalez, Kenneth H. Shain, Steven Grant
Journal: Blood Advances
Blood Adv (2021) 5 (19): 3776–3788.
https://doi.org/10.1182/bloodadvances.2020003597
Published: 2021
Includes: Supplemental data
Journal Articles

Enhanced self-renewal of human long-term hematopoietic stem cells by a sulfamoyl benzoate derivative targeting p18 INK4C

Yinghui Li, Wenshan Zhang, Yu Zhang, Yahui Ding, Ming Yang, Mei He, Xiaolei Liu, Jiali Gu, Shiqi Xu, Zhiwei Feng, Yafang Li, Jingjing Yin, Huier Gao, Henan Song, Hui Xu, Chaoqun Wang, Qing Ji, Shihui Ma, Wanzhu Yang, Weiping Yuan, Xiang-Qun Xie, Tao Cheng, Yingdai Gao
Journal: Blood Advances
Blood Adv (2021) 5 (17): 3362–3372.
https://doi.org/10.1182/bloodadvances.2020004054
Published: 2021
Includes: Supplemental data
Journal Articles

Arhgef2 regulates mitotic spindle orientation in hematopoietic stem cells and is essential for productive hematopoiesis

Derek C. H. Chan, Joshua Xu, Ana Vujovic, Nicholas Wong, Victor Gordon, Laura P. M. H. de Rooij, Steven Moreira, Cailin E. Joyce, Jose La Rose, María-José Sandí, Bradley W. Doble, Carl D. Novina, Robert K. Rottapel, Kristin J. Hope
Journal: Blood Advances
Blood Adv (2021) 5 (16): 3120–3133.
https://doi.org/10.1182/bloodadvances.2020002539
Published: 2021
Includes: Supplemental data
Journal Articles

Using mitochondrial activity to select for potent human hematopoietic stem cells

Jiajing Qiu, Jana Gjini, Tasleem Arif, Kateri Moore, Miao Lin, Saghi Ghaffari
Journal: Blood Advances
Blood Adv (2021) 5 (6): 1605–1616.
https://doi.org/10.1182/bloodadvances.2020003658
Published: 2021
Includes: Supplemental data
Journal Articles

Autophagy is dispensable for the maintenance of hematopoietic stem cells in neonates

Michihiro Hashimoto, Terumasa Umemoto, Ayako Nakamura-Ishizu, Takayoshi Matsumura, Tomomasa Yokomizo, Maiko Sezaki, Hitoshi Takizawa, Toshio Suda
Journal: Blood Advances
Blood Adv (2021) 5 (6): 1594–1604.
https://doi.org/10.1182/bloodadvances.2020002410
Published: 2021
Includes: Supplemental data
Journal Articles

Unexpected redundancy of Gpr56 and Gpr97 during hematopoietic cell development and differentiation

Antonio Maglitto, Samanta A. Mariani, Emma de Pater, Carmen Rodriguez-Seoane, Chris S. Vink, Xianhua Piao, Mari-Liis Lukke, Elaine Dzierzak
Journal: Blood Advances
Blood Adv (2021) 5 (3): 829–842.
https://doi.org/10.1182/bloodadvances.2020003693
Published: 2021
Includes: Supplemental data
Journal Articles

Naive T-cell depletion in stem cell transplantation

Marie Bleakley
Journal: Blood Advances
Blood Adv (2020) 4 (19): 4980.
https://doi.org/10.1182/bloodadvances.2020001888
Published: 2020
Includes: Supplemental data
Journal Articles

Guideline-based indicators for adult patients with myelodysplastic syndromes

Kristina Stojkov, Tobias Silzle, Georg Stussi, David Schwappach, Juerg Bernhard, David Bowen, Jaroslav Čermák, Avinash G. Dinmohamed, Corien Eeltink, Sabrina Eggmann, Pierre Fenaux, Ulrich Germing, Manuel Haschke, Eva Hellstrom-Lindberg, Monika Heger, Arjan A. van de Loosdrecht, Jakob Passweg, Michael Pfeilstöcker, Uwe Platzbecker, Luca Malcovati, António Medina de Almeida, Moshe Mittelman, Christine Morgenthaler, David P. Steensma, Valeria Santini, Reinhard Stauder, Argiris Symeonidis, Sämi Schär, Charlotte Maddox, Theo de Witte, Julia Bohlius, Nicolas Bonadies
Journal: Blood Advances
Blood Adv (2020) 4 (16): 4029–4044.
https://doi.org/10.1182/bloodadvances.2020002314
Published: 2020
Includes: Supplemental data
Journal Articles

C/EBPβ isoforms sequentially regulate regenerating mouse hematopoietic stem/progenitor cells

Atsushi Sato, Naoka Kamio, Asumi Yokota, Yoshihiro Hayashi, Akihiro Tamura, Yasuo Miura, Taira Maekawa, Hideyo Hirai
Journal: Blood Advances
Blood Adv (2020) 4 (14): 3343–3356.
https://doi.org/10.1182/bloodadvances.2018022913
Published: 2020
Includes: Supplemental data
Journal Articles

Reduced-intensity single-unit unrelated cord blood transplant with optional immune boost for nonmalignant disorders

Clinical Trials & Observations
Mark T. Vander Lugt, Xiaohua Chen, Maria L. Escolar, Beth A. Carella, Jessie L. Barnum, Randy M. Windreich, Memphis J. Hill, Michelle Poe, Rebecca A. Marsh, Heather Stanczak, Elizabeth O. Stenger, Paul Szabolcs
Journal: Blood Advances
Blood Adv (2020) 4 (13): 3041–3052.
https://doi.org/10.1182/bloodadvances.2020001940
Published: 2020
Includes: Supplemental data
Journal Articles

Enhanced engraftment of human myelofibrosis stem and progenitor cells in MISTRG mice

Veronika Lysenko, Nicole Wildner-Verhey van Wijk, Kathrin Zimmermann, Marie-Christine Weller, Marco Bühler, Mattheus H. E. Wildschut, Patrick Schürch, Christine Fritz, Ulrich Wagner, Laura Calabresi, Bethan Psaila, Richard A. Flavell, Alessandro M. Vannucchi, Adam J. Mead, Peter J. Wild, Stefan Dirnhofer, Markus G. Manz, Alexandre P. A. Theocharides
Journal: Blood Advances
Blood Adv (2020) 4 (11): 2477–2488.
https://doi.org/10.1182/bloodadvances.2019001364
Published: 2020
Includes: Supplemental data
Journal Articles

Keating AK, Langenhorst J, Wagner JE, et al. The influence of stem cell source on transplant outcomes for pediatric patients with acute myeloid leukemia. Blood Adv. 2019;3(7):1118-1128.

Journal: Blood Advances
Blood Adv (2020) 4 (6): 1081.
https://doi.org/10.1182/bloodadvances.2020001753
Published: 2020
Journal Articles

The stem cell–specific long noncoding RNA HOXA10-AS in the pathogenesis of KMT2A -rearranged leukemia

Sina Al-Kershi, Raj Bhayadia, Michelle Ng, Lonneke Verboon, Stephan Emmrich, Lucie Gack, Adrian Schwarzer, Till Strowig, Dirk Heckl, Jan-Henning Klusmann
Journal: Blood Advances
Blood Adv (2019) 3 (24): 4252–4263.
https://doi.org/10.1182/bloodadvances.2019032029
Published: 2019
Includes: Supplemental data
Journal Articles

Longitudinal assessment of clonal mosaicism in human hematopoiesis via mitochondrial mutation tracking

Caleb A. Lareau, Leif S. Ludwig, Vijay G. Sankaran
Journal: Blood Advances
Blood Adv (2019) 3 (24): 4161–4165.
https://doi.org/10.1182/bloodadvances.2019001196
Published: 2019
Includes: Supplemental data
Journal Articles

Stem cell mutations can be detected in myeloma patients years before onset of secondary leukemias

Clinical Trials & Observations
Ashwin Sridharan, Carolina D. Schinke, George Georgiev, Mariana Da Silva Ferreira, Victor Thiruthuvanathan, Ian MacArthur, Tushar D. Bhagat, Gaurav S. Choudhary, Srinivas Aluri, Jiahao Chen, Kith Pradhan, Yu Xia, Maya Panjikaran, Gregory Sims, Chirag K. Bhagat, Ryan Bender, Lauryn Keeler, Armin Graber, Christoph Heuck, Frederick A. Fletcher, Daisy Alapat, Niels Weinhold, Sarah K. Johnson, Amittha Wickrema, Bart Barlogie, Gareth J. Morgan, Aditi Shastri, Ulrich Steidl, Britta Will, Amit Verma
Journal: Blood Advances
Blood Adv (2019) 3 (23): 3962–3967.
https://doi.org/10.1182/bloodadvances.2019000731
Published: 2019
Includes: Supplemental data
Journal Articles

Human models of NUP98-KDM5A megakaryocytic leukemia in mice contribute to uncovering new biomarkers and therapeutic vulnerabilities

Sophie Cardin, Mélanie Bilodeau, Mathieu Roussy, Léo Aubert, Thomas Milan, Loubna Jouan, Alexandre Rouette, Louise Laramée, Patrick Gendron, Jean Duchaine, Hélène Decaluwe, Jean-François Spinella, Stéphanie Mourad, Françoise Couture, Daniel Sinnett, Élie Haddad, Josette-Renée Landry, Jing Ma, R. Keith Humphries, Philippe P. Roux, Josée Hébert, Tanja A. Gruber, Brian T. Wilhelm, Sonia Cellot
Journal: Blood Advances
Blood Adv (2019) 3 (21): 3307–3321.
https://doi.org/10.1182/bloodadvances.2019030981
Published: 2019
Includes: Supplemental data
Journal Articles

Cranberry A-type proanthocyanidins selectively target acute myeloid leukemia cells

Laura M. Bystrom, Daniel P. Bezerra, Hsiao-Ting Hsu, Hongliang Zong, Luis A. Lara-Martínez, Jeanne P. De Leon, Megan Emmanuel, David Méry, Sara Gardenghi, Duane Hassane, Catherine C. Neto, Susanna Cunningham-Rundles, Michael W. Becker, Stefano Rivella, Monica L. Guzman
Journal: Blood Advances
Blood Adv (2019) 3 (21): 3261–3265.
https://doi.org/10.1182/bloodadvances.2018026633
Published: 2019
Includes: Supplemental data
Journal Articles

Serum Flt3 ligand is a biomarker of progenitor cell mass and prognosis in acute myeloid leukemia

Paul Milne, Charlotte Wilhelm-Benartzi, Michael R. Grunwald, Venetia Bigley, Richard Dillon, Sylvie D. Freeman, Kathleen Gallagher, Amy Publicover, Sarah Pagan, Helen Marr, Gail L. Jones, Anne M. Dickinson, Angela Grech, Alan K. Burnett, Nigel H. Russell, Mark Levis, Steven Knapper, Matthew Collin
Journal: Blood Advances
Blood Adv (2019) 3 (20): 3052–3061.
https://doi.org/10.1182/bloodadvances.2019000197
Published: 2019
Includes: Supplemental data
Journal Articles

High-efficiency CRISPR induction of t(9;11) chromosomal translocations and acute leukemias in human blood stem cells

Johan Jeong, Astraea Jager, Pablo Domizi, Mara Pavel-Dinu, Linda Gojenola, Masayuki Iwasaki, Michael C. Wei, Feng Pan, James L. Zehnder, Matthew H. Porteus, Kara L. Davis, Michael L. Cleary
Journal: Blood Advances
Blood Adv (2019) 3 (19): 2825–2835.
https://doi.org/10.1182/bloodadvances.2019000450
Published: 2019
Includes: Supplemental data
Journal Articles

Kinetics of immune cell reconstitution predict survival in allogeneic bone marrow and G-CSF–mobilized stem cell transplantation

Clinical Trials & Observations
Edmund K. Waller, Brent R. Logan, Mingwei Fei, Stephanie J. Lee, Dennis Confer, Alan Howard, Shanmuganathan Chandrakasan, Claudio Anasetti, Shanelle M. Fernando, Cynthia R. Giver
Journal: Blood Advances
Blood Adv (2019) 3 (15): 2250–2263.
https://doi.org/10.1182/bloodadvances.2018029892
Published: 2019
Includes: Supplemental data