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Journal Articles

IFN-γ signature in the plasma proteome distinguishes pediatric hemophagocytic lymphohistiocytosis from sepsis and SIRS

Howard Lin, Brooks P. Scull, Baruch R. Goldberg, Harshal A. Abhyankar, Olive E. Eckstein, Daniel J. Zinn, Joseph Lubega, Jennifer Agrusa, Nader El Mallawaney, Nitya Gulati, Lisa Forbes, Ivan Chinn, Rikhia Chakraborty, Jessica Velasquez, Jordana Goldman, Dalia Bashir, Fong Lam, Eyal Muscal, Michael. M. Henry, Jay N. Greenberg, Stephan Ladisch, Michelle L. Hermiston, Lauren K. Meyer, Michael Jeng, Ahmed Naqvi, Kenneth McClain, Trung Nguyen, Hector Wong, Tsz-Kwong Man, Michael B. Jordan, Carl E. Allen
Journal: Blood Advances
Blood Adv (2021) 5 (17): 3457–3467.
https://doi.org/10.1182/bloodadvances.2021004287
Published: 2021
Includes: Supplemental data
Journal Articles

Discovery and validation of a novel subgroup and therapeutic target in idiopathic multicentric Castleman disease

Sheila K. Pierson, Sushila Shenoy, Ana B. Oromendia, Alexander M. Gorzewski, Ruth-Anne Langan Pai, Christopher Shield Nabel, Jason R. Ruth, Sophia A. T. Parente, Daniel J. Arenas, Mary Guilfoyle, Manjula Reddy, Michael Weinblatt, Nancy Shadick, Mark Bower, Alessia Dalla Pria, Yasufumi Masaki, Laura Katz, Jason Mezey, Philip Beineke, David Lee, Craig Tendler, Taku Kambayashi, Alexander Fosså, Frits van Rhee, David C. Fajgenbaum
Journal: Blood Advances
Blood Adv (2021) 5 (17): 3445–3456.
https://doi.org/10.1182/bloodadvances.2020004016
Published: 2021
Includes: Supplemental data
Journal Articles

Long-term effect of hematopoietic cell transplantation on systemic inflammation in patients with mucopolysaccharidoses

Brigitte T.A. van den Broek, Caroline A. Lindemans, Jaap Jan Boelens, Eveline M. Delemarre, Julia Drylewicz, Nanda Verhoeven-Duif, Peter M. van Hasselt, Stefan Nierkens
Journal: Blood Advances
Blood Adv (2021) 5 (16): 3092–3101.
https://doi.org/10.1182/bloodadvances.2020003824
Published: 2021
Includes: Supplemental data
Journal Articles

Blueprint for the discovery of biomarkers of toxicity and efficacy for CAR T cells and T-cell engagers

Clinical Trials & Observations
Sophie Paczesny, Marcelo C. Pasquini, Steven Z. Pavletic, Amit Agarwal, Stephen Spellman, Leslie Kean, Chantale Bernatchez, Juliane Gust, Verena Staedtke, Miguel-Angel Perales
Journal: Blood Advances
Blood Adv (2021) 5 (11): 2519–2522.
https://doi.org/10.1182/bloodadvances.2021004604
Published: 2021
Includes: Supplemental data
Journal Articles

Oxidized mitochondrial DNA released after inflammasome activation is a disease biomarker for myelodysplastic syndromes

Grace A. Ward, Kathy L. McGraw, Farnoosh Abbas-Aghababazadeh, Benjamin S. Meyer, Amy F. McLemore, Nicole D. Vincelette, Nghi B. Lam, Amy L. Aldrich, Najla H. Al Ali, Eric Padron, Javier Pinilla-Ibarz, Erico Masala, Valeria Santini, Olivier Kosmider, Michaela Fontenay, Pierre Fenaux, Joseph Johnson, Brooke L. Fridley, Alan F. List
Journal: Blood Advances
Blood Adv (2021) 5 (8): 2216–2228.
https://doi.org/10.1182/bloodadvances.2020003475
Published: 2021
Includes: Supplemental data
Journal Articles

Caloric and nutrient restriction to augment chemotherapy efficacy for acute lymphoblastic leukemia: the IDEAL trial

Clinical Trials & Observations
Etan Orgel, Celia Framson, Rubi Buxton, Jiyoon Kim, Gang Li, Jonathan Tucci, David R. Freyer, Weili Sun, Matthew J. Oberley, Christina Dieli-Conwright, Steven D. Mittelman
Journal: Blood Advances
Blood Adv (2021) 5 (7): 1853–1861.
https://doi.org/10.1182/bloodadvances.2020004018
Published: 2021
Includes: Supplemental data
Journal Articles

Heterogeneous NLRP3 inflammasome signature in circulating myeloid cells as a biomarker of COVID-19 severity

Clinical Trials & Observations
Johan Courjon, Océane Dufies, Alexandre Robert, Laurent Bailly, Cédric Torre, David Chirio, Julie Contenti, Sébastien Vitale, Céline Loubatier, Anne Doye, Christelle Pomares-Estran, Géraldine Gonfrier, Romain Lotte, Patrick Munro, Orane Visvikis, Jean Dellamonica, Valérie Giordanengo, Michel Carles, Laurent Yvan-Charvet, Stoyan Ivanov, Patrick Auberger, Arnaud Jacquel, Laurent Boyer
Journal: Blood Advances
Blood Adv (2021) 5 (5): 1523–1534.
https://doi.org/10.1182/bloodadvances.2020003918
Published: 2021
Includes: Supplemental data
Journal Articles

A neutrophil activation signature predicts critical illness and mortality in COVID-19

Clinical Trials & Observations
Matthew L. Meizlish, Alexander B. Pine, Jason D. Bishai, George Goshua, Emily R. Nadelmann, Michael Simonov, C-Hong Chang, Hanming Zhang, Marcus Shallow, Parveen Bahel, Kent Owusu, Yu Yamamoto, Tanima Arora, Deepak S. Atri, Amisha Patel, Rana Gbyli, Jennifer Kwan, Christine H. Won, Charles Dela Cruz, Christina Price, Jonathan Koff, Brett A. King, Henry M. Rinder, F. Perry Wilson, John Hwa, Stephanie Halene, William Damsky, David van Dijk, Alfred I. Lee, Hyung J. Chun
Journal: Blood Advances
Blood Adv (2021) 5 (5): 1164–1177.
https://doi.org/10.1182/bloodadvances.2020003568
Published: 2021
Includes: Supplemental data
Journal Articles

Antileukemic efficacy of a potent artemisinin combined with sorafenib and venetoclax

Blake S. Moses, Samantha McCullough, Jennifer M. Fox, Bryan T. Mott, Søren M. Bentzen, MinJung Kim, Jeffrey W. Tyner, Rena G. Lapidus, Ashkan Emadi, Michelle A. Rudek, Tami J. Kingsbury, Curt I. Civin
Journal: Blood Advances
Blood Adv (2021) 5 (3): 711–724.
https://doi.org/10.1182/bloodadvances.2020003429
Published: 2021
Includes: Supplemental data
Journal Articles

Integrin VLA-4 as a PET imaging biomarker of hyper-adhesion in transgenic sickle mice

Lydia A. Perkins, Lea Nyiranshuti, Lynda Little-Ihrig, Joseph D. Latoche, Kathryn E. Day, Qin Zhu, Sina Tavakoli, Prithu Sundd, Enrico M. Novelli, Carolyn J. Anderson
Journal: Blood Advances
Blood Adv (2020) 4 (17): 4102–4112.
https://doi.org/10.1182/bloodadvances.2020002642
Published: 2020
Includes: Supplemental data
Journal Articles

Physical activity in children at risk of postthrombotic sequelae: a pilot randomized controlled trial

Clinical Trials & Observations
Rida Hasan, Maria Hanna, Song Zhang, Kendra Malone, Elizabeth Tong, Niavana Salas, Ravi Sarode, Janna Journeycake, Ayesha Zia
Journal: Blood Advances
Blood Adv (2020) 4 (15): 3767–3775.
https://doi.org/10.1182/bloodadvances.2020002096
Published: 2020
Includes: Supplemental data
Journal Articles

ADAMTS13 and VWF activities guide individualized caplacizumab treatment in patients with aTTP

Clinical Trials & Observations
Linus A. Völker, Jessica Kaufeld, Wolfgang Miesbach, Sebastian Brähler, Martin Reinhardt, Lucas Kühne, Anja Mühlfeld, Adrian Schreiber, Jens Gaedeke, Markus Tölle, Wolfram J. Jabs, Fedai Özcan, Silke Markau, Matthias Girndt, Frederic Bauer, Timm H. Westhoff, Helmut Felten, Martin Hausberg, Marcus Brand, Jens Gerth, Markus Bieringer, Martin Bommer, Stefan Zschiedrich, Johanna Schneider, Saban Elitok, Alexander Gawlik, Anja Gäckler, Andreas Kribben, Vedat Schwenger, Ulf Schoenermarck, Maximilian Roeder, Jörg Radermacher, Jörn Bramstedt, Anke Morgner, Regina Herbst, Ana Harth, Sebastian A. Potthoff, Charis von Auer, Ralph Wendt, Hildegard Christ, Paul T. Brinkkoetter, Jan Menne
Journal: Blood Advances
Blood Adv (2020) 4 (13): 3093–3101.
https://doi.org/10.1182/bloodadvances.2020001987
Published: 2020
Includes: Supplemental data
Journal Articles

Dickkopf-related protein 3 is a novel biomarker for chronic GVHD after allogeneic hematopoietic cell transplantation

Yoshihiro Inamoto, Paul J. Martin, Stephanie J. Lee, Amin A. Momin, Laura Tabellini, Lynn E. Onstad, Joseph Pidala, Mary E. D. Flowers, Richard L. Lawler, Hiroyuki Katayama, Samir Hanash, John A. Hansen
Journal: Blood Advances
Blood Adv (2020) 4 (11): 2409–2417.
https://doi.org/10.1182/bloodadvances.2020001485
Published: 2020
Includes: Supplemental data
Journal Articles

A phase 1 trial of itacitinib, a selective JAK1 inhibitor, in patients with acute graft-versus-host disease

Clinical Trials & Observations
Mark A. Schroeder, H. Jean Khoury, Madan Jagasia, Haris Ali, Gary J. Schiller, Karl Staser, Jaebok Choi, Leah Gehrs, Michael C. Arbushites, Ying Yan, Peter Langmuir, Nithya Srinivas, Michael Pratta, Miguel-Angel Perales, Yi-Bin Chen, Gabrielle Meyers, John F. DiPersio
Journal: Blood Advances
Blood Adv (2020) 4 (8): 1656–1669.
https://doi.org/10.1182/bloodadvances.2019001043
Published: 2020
Includes: Supplemental data
Journal Articles

Guerrero CLH, Yamashita Y, Miyara M, et al. Proteomic profiling of HTLV-1 carriers and ATL patients reveals sTNFR2 as a novel diagnostic biomarker for acute ATL. Blood Adv. 2020;4(6):1062-1071.

Journal: Blood Advances
Blood Adv (2020) 4 (8): 1647.
https://doi.org/10.1182/bloodadvances.2020001997
Published: 2020
Journal Articles

Facilitating resolution of life-threatening acute GVHD with human chorionic gonadotropin and epidermal growth factor

Clinical Trials & Observations
Shernan G. Holtan, Andrea L. Hoeschen, Qing Cao, Mukta Arora, Veronika Bachanova, Claudio G. Brunstein, Jeffrey S. Miller, Armin Rashidi, Arne Slungaard, Celalettin Ustun, Gregory M. Vercellotti, Erica D. Warlick, Brian C. Betts, Najla El Jurdi, Fiona He, Chi Chen, Isha Gandhi, John E. Wagner, Bruce R. Blazar, Pamala Ann Jacobson, Ashraf Shabaneh, Jinhua Wang, Angela Panoskaltsis-Mortari, Margaret L. MacMillan, Daniel J. Weisdorf
Journal: Blood Advances
Blood Adv (2020) 4 (7): 1284–1295.
https://doi.org/10.1182/bloodadvances.2019001259
Published: 2020
Includes: Supplemental data
Journal Articles

SAKK38/07 study: integration of baseline metabolic heterogeneity and metabolic tumor volume in DLBCL prognostic model

Clinical Trials & Observations
Luca Ceriani, Giuseppe Gritti, Luciano Cascione, Maria Cristina Pirosa, Angela Polino, Teresa Ruberto, Anastasios Stathis, Andrea Bruno, Alden A. Moccia, Luca Giovanella, Stefanie Hayoz, Sämi Schär, Stefan Dirnhofer, Alessandro Rambaldi, Giovanni Martinelli, Christoph Mamot, Emanuele Zucca
Journal: Blood Advances
Blood Adv (2020) 4 (6): 1082–1092.
https://doi.org/10.1182/bloodadvances.2019001201
Published: 2020
Journal Articles

Proteomic profiling of HTLV-1 carriers and ATL patients reveals sTNFR2 as a novel diagnostic biomarker for acute ATL

Carmina Louise Hugo Guerrero, Yoshiko Yamashita, Megumi Miyara, Naoki Imaizumi, Megumi Kato, Shugo Sakihama, Masaki Hayashi, Takashi Miyagi, Kaori Karimata, Junnosuke Uchihara, Kazuiku Ohshiro, Junpei Todoroki, Sawako Nakachi, Satoko Morishima, Kennosuke Karube, Yuetsu Tanaka, Hiroaki Masuzaki, Takuya Fukushima
Journal: Blood Advances
Blood Adv (2020) 4 (6): 1062–1071.
https://doi.org/10.1182/bloodadvances.2019001429
Published: 2020
Includes: Supplemental data
Journal Articles

Phosphorylated ERK1/2 in CD4 T cells is associated with acute GVHD in allogeneic hematopoietic stem cell transplantation

Clinical Trials & Observations
Hidekazu Itamura, Takero Shindo, Satoshi Yoshioka, Takayuki Ishikawa, Shinya Kimura
Journal: Blood Advances
Blood Adv (2020) 4 (4): 667–671.
https://doi.org/10.1182/bloodadvances.2019000343
Published: 2020
Includes: Supplemental data
Journal Articles

Propranolol inhibits molecular risk markers in HCT recipients: a phase 2 randomized controlled biomarker trial

Clinical Trials & Observations
Jennifer M. Knight, J. Douglas Rizzo, Parameswaran Hari, Marcelo C. Pasquini, Karen E. Giles, Anita D’Souza, Brent R. Logan, Mehdi Hamadani, Saurabh Chhabra, Binod Dhakal, Nirav Shah, Deepika Sriram, Mary M. Horowitz, Steve W. Cole
Journal: Blood Advances
Blood Adv (2020) 4 (3): 467–476.
https://doi.org/10.1182/bloodadvances.2019000765
Published: 2020
Includes: Supplemental data