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Issue Archive

Volume 9, Issue 7
April 8 2025
In Progress
Blood Advances Cover Image for Volume 9, Issue 7

CLINICAL TRIALS AND OBSERVATIONS

Phase 2 trial of ibrutinib and nivolumab in patients with relapsed CNS lymphomas
Clinical Trials & Observations
Dai Chihara,Raphael E. Steiner,Ranjit Nair,Lei Feng,Sairah Ahmed,Paolo Strati,Luis Malpica,Donna P. Griffith,Shivon A. Mathew,Wirt Montinez,Gita Masand,Felipe Samaniego,Maria A. Rodriguez,Fredrick B. Hagemeister,Luis E. Fayad,Swaminathan P. Iyer,Loretta J. Nastoupil,Sattva S. Neelapu,Christopher R. Flowers,Jason R. Westin
View Articletitled, Phase 2 trial of ibrutinib and nivolumab in patients with relapsed CNS lymphomas
Changes in gut microbiota predict neutropenia after induction treatment in childhood acute lymphoblastic leukemia
Clinical Trials & Observations
Maria Ebbesen Sørum,Ulrika Boulund,Silvia De Pietri,Sarah Weischendorff,Christian Enevold,Mathias Rathe,Bodil Als-Nielsen,Henrik Hasle,Sünje Pamp,Jakob Stokholm,Klaus Müller
View Articletitled, Changes in gut microbiota predict neutropenia after induction treatment in childhood acute lymphoblastic leukemia
Supplemental data
Trial eligibility, treatment patterns, and outcome for venetoclax-based therapy in AML: a prospective cohort study
Clinical Trials & Observations
Ofir Wolach,Itai Levi,Boaz Nachmias,Sigal Tavor,Irina Amitai,Yishai Ofran,Chezi Ganzel,Tsila Zuckerman,Doaa Okasha,Ilana Hellmann,Tamar Tadmor,Najib Dally,Jonathan Canaani,Galia Stemer,Moshe Grunspan,Adi Jacob Berger,Neta Frankel,Jenia Berelovich,Alexandra Bleterman,Moran Barak,Raanan Cohen,Yakir Moshe,on behalf of the Israeli Acute Leukemia Working Group
View Articletitled, Trial eligibility, treatment patterns, and outcome for venetoclax-based therapy in AML: a prospective cohort study
Supplemental data
Allogeneic off-the-shelf CAR T-cell therapy for relapsed or refractory B-cell malignancies
Clinical Trials & Observations
Sanam Shahid,Susan E. Prockop,Georgia C. Flynn,Audrey Mauguen,Charlie O. White,Jennifer Bieler,Devin McAvoy,Kinga Hosszu,Maria I. Cancio,Ann A. Jakubowski,Andromachi Scaradavou,Jaap Jan Boelens,Craig S. Sauter,Miguel-Angel Perales,Sergio A. Giralt,Clare Taylor,Jagrutiben Chaudhari,Xiuyan Wang,Isabelle Rivière,Michel Sadelain,Renier J. Brentjens,Nancy A. Kernan,Richard J. O'Reilly,Kevin J. Curran
View Articletitled, Allogeneic off-the-shelf CAR T-cell therapy for relapsed or refractory B-cell malignancies
Supplemental data

RESEARCH LETTER

Desensitization to calaspargase pegol appears to be less successful than pegaspargase
Milre Matherne,John C. Panetta,Jaclyn Hopp,Hiroto Inaba,Ching-Hon Pui,Seth E. Karol,Hope D. Swanson
View Articletitled, Desensitization to calaspargase pegol appears to be less successful than pegaspargase
Psychiatric and substance use disorders predict poor outcomes in older veterans with acute myeloid leukemia
Michelle H. Lee,Jennifer La,Mary T. Brophy,Nhan V. Do,Camille V. Edwards,Clark DuMontier,Gabriela S. Hobbs,Nathanael R. Fillmore
View Articletitled, Psychiatric and substance use disorders predict poor outcomes in older veterans with acute myeloid leukemia
Supplemental data
Outcomes of older adults and frail patients receiving idecabtagene vicleucel: a CIBMTR study
Othman Salim Akhtar,Temitope Oloyede,Ruta Brazauskas,Aimaz Afrough,Hamza Hashmi,Surbhi Sidana,Nausheen Ahmed,Matthew Bye,Doris Hansen,Christopher Ferreri,Binod Dhakal,Devender Dhanda,Melanie Harrison,Amani Kitali,Heather Landau,Abu-Sayeef Mirza,Jinalben Patel,Pallavi Patwardhan,Muzaffar Qazilbash,Krina Patel,Taiga Nishihori,Siddhartha Ganguly,Lohith Gowda,Larry D. Anderson, Jr.,Marcelo C. Pasquini,Saad Usmani,Ciara Louise Freeman
View Articletitled, Outcomes of older adults and frail patients receiving idecabtagene vicleucel: a CIBMTR study
Supplemental data

PLATELETS AND THROMBOPOIESIS

The role of genetic sequencing in the diagnostic workup for chronic immune thrombocytopenia
Nehal Joshi,Hana Lango-Allen,Kate Downes,Ilenia Simeoni,Camelia Vladescu,Deena Paul,Alice Hart,Christine Ademokun,Nichola Cooper
View Articletitled, The role of genetic sequencing in the diagnostic workup for chronic immune thrombocytopenia
Supplemental data

IMMUNOBIOLOGY AND IMMUNOTHERAPY

Fc mutagenesis enhances the functionality of anti-RhD monoclonal antibodies
Behnaz Heydarchi,Damian B. D'Silva,Huon Wong,Ethan D. Goddard-Borger,Ian P. Wicks
View Articletitled, Fc mutagenesis enhances the functionality of anti-RhD monoclonal antibodies
Differential antibody response to EBV proteome following EBVST immunotherapy in EBV-associated lymphomas
Clinical Trials & Observations
Yomani D. Sarathkumara,Nathan W. Van Bibber,Zhiwei Liu,Helen E. Heslop,Rayne H. Rouce,Anna E. Coghill,Cliona M. Rooney,Carla Proietti,Denise L. Doolan
View Articletitled, Differential antibody response to EBV proteome following EBVST immunotherapy in EBV-associated lymphomas
Supplemental data

MYELOID NEOPLASIA

JAK2 p.R564 germ line variants associated with hereditary thrombocythemia and hematologic neoplasms
Clinical Trials & Observations
Brittany L. Stewart,Hetty E. Carraway,Adriana L. Alvarez,Harry Lesmana,John Molina,Zheng Jin Tu,David S. Bosler,Aaron Gerds,Babal Jha,Emilia Calvaresi,Joy Nakitandwe,Abhay Singh
View Articletitled, <em>JAK2</em> p.R564 germ line variants associated with hereditary thrombocythemia and hematologic neoplasms
Germ line JAK2 variants and hereditary blood cancers
Joseph Cannova,Michael W. Drazer
View Articletitled, Germ line JAK2 variants and hereditary blood cancers
Dual ASXL1 and CSF3R mutations drive myeloid-biased stem cell expansion and enhance neutrophil differentiation
Lucie Darmusey,Anna J. Bagley,Thai T. Nguyen,Hanqian L. Carlson,Hunter Blaylock,Shawn B. Shrestha,Amara Pang,Samantha Tauchmann,Sarah C. Taylor,Amy C. Foley,Katia E. Niño,Eric M. Pietras,Theodore P. Braun,Julia E. Maxson
View Articletitled, Dual <em>ASXL1</em> and <em>CSF3R</em> mutations drive myeloid-biased stem cell expansion and enhance neutrophil differentiation
Supplemental data

SYSTEMATIC REVIEW

Solitary plasmacytoma: single-institution experience, and systematic review and meta-analysis of clinical outcomes
Charalampos Charalampous,Jean-Sebastien Claveau,Prashant Kapoor,Moritz Binder,Francis K. Buadi,Joselle Cook,David Dingli,Angela Dispenzieri,Amie L. Fonder,Morie A. Gertz,Wilson Gonsalves,Suzanne R. Hayman,Miriam A. Hobbs,Yi L. Hwa,Taxiarchis Kourelis,Martha Q. Lacy,Nelson Leung,Yi Lin,Rahma Warsame,Robert A. Kyle,S. Vincent Rajkumar,Shaji K. Kumar
View Articletitled, Solitary plasmacytoma: single-institution experience, and systematic review and meta-analysis of clinical outcomes
Supplemental data

VASCULAR BIOLOGY

Nbeal2 knockout mice are not protected against hypoxia-induced pulmonary vascular remodeling and pulmonary hypertension
Janelle N. Posey,Mariah Jordan,Caitlin V. Lewis,Christina Sul,Evgenia Dobrinskikh,Delaney Swindle,Frederik Denorme,David Irwin,Jorge Di Paola,Kurt Stenmark,Eva S. Nozik,Cassidy Delaney
View Articletitled, Nbeal2 knockout mice are not protected against hypoxia-induced pulmonary vascular remodeling and pulmonary hypertension
Supplemental data

Inside Blood Advances

Germ line JAK2 variants and hereditary blood cancers
Joseph Cannova,Michael W. Drazer
View Articletitled, Germ line JAK2 variants and hereditary blood cancers
Best but not perfect: indirect measure of low iron stores
Franklin Njoku,Victor R. Gordeuk
View Articletitled, Best but not perfect: indirect measure of low iron stores

Red Cells, Iron, and Erythropoiesis

Ferritin outperforms other biomarkers in predicting bone marrow iron stores in patients with hematologic disorders
Tapio Lahtiharju,Paula Savola,Anna Lempiäinen,Tuukka Helin,Lotta Joutsi-Korhonen
View Articletitled, Ferritin outperforms other biomarkers in predicting bone marrow iron stores in patients with hematologic disorders
Supplemental data
Best but not perfect: indirect measure of low iron stores
Franklin Njoku,Victor R. Gordeuk
View Articletitled, Best but not perfect: indirect measure of low iron stores

HEALTH SERVICES AND OUTCOMES

Anxiety and depression among patients newly diagnosed with lymphoma and myeloma
Oreofe O. Odejide,Angel M. Cronin,Tamryn F. Gray,Tsotso Ablorh,Anna Ying,Amelia Yang,Cheyenne Ashley,Anna Tidswell,Eleanor Shi,Miryam Yusufov,Gregory A. Abel,Lizabeth Roemer
View Articletitled, Anxiety and depression among patients newly diagnosed with lymphoma and myeloma

TRANSPLANTATION

Pretransplant MRD does not seem to affect survival in NPM1-mutated AML undergoing allogeneic stem cell transplantation
Alessia Fraccaroli,Vindi Jurinovic,Klaus Hirschbühl,Elena Stauffer,Katrin Koch,Stephan Breitkopf,Sarah Haebe,Heidrun Drolle,Maja Rothenberg-Thurley,Annika Dufour,Klaus H. Metzeler,Karsten Spiekermann,Marcus Hentrich,Andreas Hausmann,Mareike Verbeek,Christoph Schmid,Tobias Herold,Johanna Tischer
View Articletitled, Pretransplant MRD does not seem to affect survival in <em>NPM1</em>-mutated AML undergoing allogeneic stem cell transplantation
Supplemental data
All Issues

Advertisement intended for health care professionals

Germ line JAK2 variants and hereditary blood cancers
Best but not perfect: indirect measure of low iron stores
Phase 2 trial of ibrutinib and nivolumab in patients with relapsed CNS lymphomas
Allogeneic off-the-shelf CAR T-cell therapy for relapsed or refractory B-cell malignancies
Differential antibody response to EBV proteome following EBVST immunotherapy in EBV-associated lymphomas

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