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Volume 9, Issue 15
August 12 2025
In Progress
Blood Advances Cover Image for Volume 9, Issue 15

Volume 9 Issue 15 | Blood Advances | American Society of Hematology

CLINICAL TRIALS AND OBSERVATIONS

Long-term follow-up of MRD-guided ibrutinib plus venetoclax in relapsed CLL: phase 2 VISION/HO141 trial
Clinical Trials & Observations
Carsten U. Niemann,Julie Dubois,Kazem Nasserinejad,Caspar da Cunha-Bang,Sabina Kersting,Lisbeth Enggaard,Gerrit J. Veldhuis,Rogier Mous,Clemens H.M. Mellink,Anne-Marie F. van der Kevie-Kersemaekers,Johan A. Dobber,Christian B. Poulsen,Wida Razawy,René Hollestein,Henrik Frederiksen,Ann Janssens,Ida Schjødt,Ellen C. Dompeling,Juha Ranti,Christian Brieghel,Mattias Mattsson,Mar Bellido,Hoa T. T. Tran,Arnon P. Kater,Mark-David Levin
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Lisocabtagene maraleucel for R/R LBCL in patients not intended for HSCT: final results of the phase 2 PILOT study
Clinical Trials & Observations
Alison Sehgal,Daanish Hoda,Peter A. Riedell,Nilanjan Ghosh,Mehdi Hamadani,Gerhard C. Hildebrandt,John E. Godwin,Patrick M. Reagan,Nina D. Wagner-Johnston,James Essell,Rajneesh Nath,Scott R. Solomon,Rebecca Champion,Edward Licitra,Suzanne Fanning,Neel K. Gupta,Victor A. Chow,Brenda Yuan,Zhi Yang,Ken Ogasawara,Jerill Thorpe,Leo I. Gordon
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Eltrombopag in combination with immunosuppressive therapy in pediatric severe aplastic anemia: phase 2 ESCALATE trial
Clinical Trials & Observations
Akiko Shimamura,Alexey Maschan,Carolyn Bennett,Sujith Samarasinghe,Jason E. Farrar,Chi-kong Li,Nongnuch Sirachainan,Bunchoo Pongtanakul,Patcharee Komvilaisak,Ludmila Zubarovskaya,Jennifer A. Rothman,Kelly Walkovich,Taizo A. Nakano,Alison A. Bertuch,Anabela Ferrao,Rukhmi Bhat,Rabi Hanna,Kathleen Overholt,Jessica Boklan,Tze Fang Wong,Qinxia Wang,Patrick Urban,Brigitte Strahm,Winfred Wang,Adrianna Vlachos,David A. Williams
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ESCALATing care? Eltrombopag in pediatric aplastic anemia
Clinical Trials & Observations
Joshua Glass,Emma M. Groarke
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Gut microbiota restoration with oral pooled fecal microbiotherapy after intensive chemotherapy: the phase 1b CIMON trial
Clinical Trials & Observations
Florent Malard,Sylvain Thepot,Thomas Cluzeau,Martin Carré,Delphine Lebon,Pierre Bories,Ollivier Legrand,Marianne Schwarz,Michael Loschi,Mathieu Meunier,Magalie Joris,Cyrielle Gasc,Juliette Jouve,Benoît Levast,Emilie Plantamura,Emmanuel Prestat,Antoine Sabourin,Béatrice Gaugler,Joel Dore,Christian Récher,Mohamad Mohty
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Molecular inflammatory expression profiles associated with the frequency of pain in individuals with sickle cell disease
Clinical Trials & Observations
Lana Mucalo Katunaric,Shuang Jia,Ashima Singh,Mark F. Roethle,Julie A. Panepinto,David C. Brousseau,Martin J. Hessner,Amanda M. Brandow
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Biomarker signatures for sickle cell pain
Kalpna Gupta,Vidhya Kumaresan
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Real-world survival outcomes in first-line ibrutinib-treated patients with high-risk CLL/SLL
Clinical Trials & Observations
John N. Allan,Tao Ran,Zhijie Ding,Jinghua He,Alex Bokun,Zaina P. Qureshi,Susan M. O’Brien
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Lymphoid Neoplasia

Genetic deregulation of REL in germinal center B cells induces generation of a pool of lymphoma precursor cells
Léa Prévaud,Karima Ferhat,Dilara Sensoy,Ophélie Téteau,Tiffany Marchiol,Quentin Lemasson,Catherine Ouk,Claire Carrion,Michel Cogné,Jean Feuillard,Christelle Vincent-Fabert,Nathalie Faumont
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Indirect comparison of epcoritamab vs chemoimmunotherapy, mosunetuzumab, or odronextamab in follicular lymphoma
Alexey V. Danilov,Swetha Kambhampati Thiruvengadam,Kim Linton,Karen Cumings,Viktor Chirikov,Alex Mutebi,Savreet Bains Chawla,Anindit Chhibber,Fernando Rivas Navarro,Felipe Marques Gonçalves,Anthony Wang,Zhijie Ding,Abualbishr Alshreef,Elena Favaro,Daniela Hoehn,Anna Sureda
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RESEARCH LETTER

T-cell dysfunction during blinatumomab therapy in pediatric acute lymphoblastic leukemia
Julie Ma,Annie Luong,Andrew Doan,Tsen Yin Lin,Lingyun Ji,Cassandra P. Wang,Seon-Jae Yoon,Teresa Rushing,Anh Duong,Miguel Villa,Chintan Parekh
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Brentuximab vedotin and nivolumab for untreated patients with Hodgkin lymphoma: long-term results
Clinical Trials & Observations
Bruce D. Cheson,Nancy L. Bartlett,Betsy Knopf,Hun J. Lee,Ranjana H. Advani,Beth Christian,Catherine S. Diefenbach,Tatyana A. Feldman,Stephen M. Ansell
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Dysregulated immune proteins in plasma in the UK Biobank predict multiple myeloma 12 years before clinical diagnosis
Joshua Fieggen,Anshul Thakur,Christopher C. Butler,Karthik Ramasamy,Anjan Thakurta,David A. Clifton,Lei Clifton
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Drug development for leukemia: comprehensive analysis of clinical trials from first report to drug approval
Clinical Trials & Observations
Kellen Cristine Tjioe,Marisol Miranda-Galvis,Kenza Mamouni,Thalyta Freitas,Muhannad Sharara,Brenda Santellano,Claudia Guillén-Lopez,Jorge E. Cortes
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RAS mutation identifies a poor prognostic molecular subtype of therapy-related myeloid neoplasm
Chung Hoow Kok,Aref Al-Kali,Daniel Thomas,Rong He,Monika M. Kutyna,Hassan Alkhateeb,Kelly Lim,Antoine N. Saliba,Carla Toop,Aasiya Matin,Hamish Scott,Naseema Gangat,Anna Brown,Abhishek Mangaonkar,Christopher N. Hahn,Kebede Begna,Kevin Hung,Patricia Greipp,William J. Hogan,Mrinal Patnaik,Mithun Shah,Devendra K. Hiwase
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THROMBOSIS AND HEMOSTASIS

Patient anti-FVIII drug antibodies bind preferentially to a subset of FVIII covalent states
Diego Butera,Aster E. Pijning,Nathan G. Avery,Carmen H. Coxon,Clive Metcalfe,Angelina Mimoun,Sébastien Lacroix-Desmazes,Paul Clint Spiegel, Jr.,Philip J. Hogg
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Exorcizing the devil of factor VIII inhibitors
Paul C. Moorehead
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A global survey on practice changes and barriers to the use of direct oral anticoagulants in children
M. Laura Avila,Erica Di Ruggiero,Jennifer Vincelli,Leonardo R. Brandão
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Inside Blood Advances

Exorcizing the devil of factor VIII inhibitors
Paul C. Moorehead
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ESCALATing care? Eltrombopag in pediatric aplastic anemia
Clinical Trials & Observations
Joshua Glass,Emma M. Groarke
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Biomarker signatures for sickle cell pain
Kalpna Gupta,Vidhya Kumaresan
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Plasma Cell Disorders

Predictive value of free light chain burden in patients with AL amyloidosis treated with bortezomib-based regimens
Brendan Saunders,Foteini Theodorakakou,Despina Fotiou,Samuel Boullt,Benjamin Evans,Meletios A. Dimopoulos,Efstathios Kastritis,Giada Bianchi
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MYELOID NEOPLASIA

Real-world effectiveness of immunoglobulin replacement for hypogammaglobulinemia and infections in multiple myeloma
Elizabeth O’Donnell,Thais Gift,Zaid Yousif,Nikhil Khandelwal,Raj Desai,Lynn Huynh,Louise Clear,Megan Pinaire,Mingchen Ye,Azeem Banatwala,Gregory Belsky,Yichuan Grace Hsieh,Christopher Herrick,Mei Sheng Duh,Shawn N. Murphy,Marie Sanchirico
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All Issues

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Exorcizing the devil of factor VIII inhibitors
ESCALATing care? Eltrombopag in pediatric aplastic anemia
Biomarker signatures for sickle cell pain
RAS mutation identifies a poor prognostic molecular subtype of therapy-related myeloid neoplasm
Indirect comparison of epcoritamab vs chemoimmunotherapy, mosunetuzumab, or odronextamab in follicular lymphoma

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