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Issue Archive

Volume 7, Issue 2
January 24 2023
Issue Cover

Table of Contents

CLINICAL TRIALS AND OBSERVATIONS

The impact of early PEG-asparaginase discontinuation in young adults with ALL: a post hoc analysis of the CALGB 10403 study
Clinical Trials & Observations
Ibrahim Aldoss,Jun Yin,Anna Wall,Krzysztof Mrózek,Michaela Liedtke,David F. Claxton,Matthew C. Foster,Frederick R. Appelbaum,Harry P. Erba,Mark R. Litzow,Martin S. Tallman,Richard M. Stone,Richard A. Larson,Anjali S. Advani,Wendy Stock,Selina M. Luger
View Articletitled, The impact of early PEG-asparaginase discontinuation in young adults with ALL: a post hoc analysis of the CALGB 10403 study
Supplemental data
Incidence and clinical impact of bleeding events in older patients with acute venous thromboembolism
Clinical Trials & Observations
Elisa Ferrazzini,Marie Méan,Odile Stalder,Andreas Limacher,Nicolas Rodondi,Drahomir Aujesky
View Articletitled, Incidence and clinical impact of bleeding events in older patients with acute venous thromboembolism
The impact of in utero transfusions on perinatal outcomes in patients with alpha thalassemia major: the UCSF registry
Clinical Trials & Observations
Marisa E. Schwab,Billie R. Lianoglou,Dawn Gano,Juan Gonzalez Velez,Isabel E. Allen,Regina Arvon,Ahmet Baschat,Diana W. Bianchi,Melissa Bitanga,Anne Bourguignon,Richard N. Brown,Bruce Chen,May Chien,Shareece Davis-Nelson,Monique W. M. de Laat,Supachai Ekwattanakit,Yvonne Gollin,Greigh Hirata,Angie Jelin,Jennifer Jolley,Paul Meyer,Jena Miller,Mary E. Norton,Keith K. Ogasawara,Tachjaree Panchalee,Erica Schindewolf,Steven W. Shaw,Tammy Stumbaugh,Alexis A. Thompson,Dena Towner,Pai-Jong Stacy Tsai,Vip Viprakasit,Emmanuel Volanakis,Li Zhang,Elliott Vichinsky,Tippi C. MacKenzie
View Articletitled, The impact of in utero transfusions on perinatal outcomes in patients with alpha thalassemia major: the UCSF registry
Supplemental data

HEMATOPOIESIS AND STEM CELLS

p16INK4A-dependent senescence in the bone marrow niche drives age-related metabolic changes of hematopoietic progenitors
Charlotte Hellmich,Edyta Wojtowicz,Jamie A. Moore,Jayna J. Mistry,Aisha Jibril,Benjamin B. Johnson,James G. W. Smith,Naiara Beraza,Kristian M. Bowles,Stuart A. Rushworth
View Articletitled, p16INK4A-dependent senescence in the bone marrow niche drives age-related metabolic changes of hematopoietic progenitors
Supplemental data

LYMPHOID NEOPLASIA

Baseline radiomics features and MYC rearrangement status predict progression in aggressive B-cell lymphoma
Clinical Trials & Observations
Jakoba J. Eertink,Gerben J. C. Zwezerijnen,Sanne E. Wiegers,Simone Pieplenbosch,Martine E. D. Chamuleau,Pieternella J. Lugtenburg,Daphne de Jong,Bauke Ylstra,Matias Mendeville,Ulrich Dührsen,Christine Hanoun,Andreas Hüttmann,Julia Richter,Wolfram Klapper,Yvonne W. S. Jauw,Otto S. Hoekstra,Henrica C. W. de Vet,Ronald Boellaard,Josée M. Zijlstra,on behalf of the PETRA consortium
View Articletitled, Baseline radiomics features and <em>MYC</em> rearrangement status predict progression in aggressive B-cell lymphoma
Supplemental data
Distinct clonal identities of B-ALLs arising after lenolidomide therapy for multiple myeloma
Erica K. Barnell,Zachary L. Skidmore,Kenneth F. Newcomer,Monique Chavez,Katie M. Campbell,Kelsy C. Cotto,Nicholas C. Spies,Marianna B. Ruzinova,Tianjiao Wang,Brooj Abro,Friederike Kreisel,Bijal A. Parikh,Eric J. Duncavage,John L. Frater,Yi-Shan Lee,Anjum Hassan,Justin A. King,Daniel R. Kohnen,Mark A. Fiala,John S. Welch,Geoffrey L. Uy,Kiran Vij,Ravi Vij,Malachi Griffith,Obi L. Griffith,Lukas D. Wartman
View Articletitled, Distinct clonal identities of B-ALLs arising after lenolidomide therapy for multiple myeloma
Supplemental data

TRANSPLANTATION

Reduction in vaso-occlusive events following stem cell transplantation in patients with sickle cell disease
Clinical Trials & Observations
Alexis Leonard,Dana Furstenau,Allistair Abraham,Deepika S. Darbari,Robert S. Nickel,Emily Limerick,Courtney Fitzhugh,Matt Hsieh,John F. Tisdale
View Articletitled, Reduction in vaso-occlusive events following stem cell transplantation in patients with sickle cell disease
Supplemental data

RESEARCH LETTERS

Direct oral Xa inhibitors for the treatment of venous thromboembolism after bariatric surgery
Margarita Kushnir,Radhika Gali,Mariam Alexander,Henny H. Billett
View Articletitled, Direct oral Xa inhibitors for the treatment of venous thromboembolism after bariatric surgery
Characteristics of VITT antibodies in patients vaccinated with Ad26.COV2.S
Angela Huynh,Donald M. Arnold,James V. Michael,Rumi Clare,James W. Smith,Mercy Daka,Monica Ianosi-Irimie,Steven E. McKenzie,John G. Kelton,Ishac Nazy
View Articletitled, Characteristics of VITT antibodies in patients vaccinated with Ad26.COV2.S
Supplemental data
CD22low/Bcl-2high expression identifies poor response to inotuzumab ozogamicin in relapsed/refractory acute lymphoblastic leukemia
Clinical Trials & Observations
Astrid Wintering,Kenichi Ishiyama,Stanley Tamaki,Courtney Tamaki,Joshua Fandel,Lingyun Ji,Brent L. Wood,Nirali N. Shah,Constance M. Yuan,Maureen M. O’Brien,Mignon L. Loh,Ernesto Diaz-Flores
View Articletitled, CD22<sup>low</sup>/Bcl-2<sup>high</sup> expression identifies poor response to inotuzumab ozogamicin in relapsed/refractory acute lymphoblastic leukemia
Supplemental data

COMMENTARY

DOACs for VTE in patients with brain cancer and brain metastases: choices, choices, choices
Richard J. Buka,David J. Sutton
View Articletitled, DOACs for VTE in patients with brain cancer and brain metastases: choices, choices, choices

RESPONSE

DOACs in patients with brain cancers: promising but still a long way to go
Michela Giustozzi,Cecilia Becattini,Fausto Roila,Giancarlo Agnelli,Mario Mandalà
View Articletitled, DOACs in patients with brain cancers: promising but still a long way to go

ERRATA

Gioacchino E, Koyunlar C, Zink J, et al. Essential role for Gata2 in modulating lineage output from hematopoietic stem cells in zebrafish. Blood Adv. 2021;5(13):2687-2700.
View Articletitled, Gioacchino E, Koyunlar C, Zink J, et al. Essential role for Gata2 in modulating lineage output from hematopoietic stem cells in zebrafish. <em>Blood Adv.</em> 2021;5(13):2687-2700.
Baronciani L, Peake I, Schneppenheim R, et al. Genotypes of European and Iranian patients with type 3 von Willebrand disease enrolled in 3WINTERS-IPS. Blood Adv. 2021;5(15):2987-3001.
View Articletitled, Baronciani L, Peake I, Schneppenheim R, et al. Genotypes of European and Iranian patients with type 3 von Willebrand disease enrolled in 3WINTERS-IPS. <em>Blood Adv</em>. 2021;5(15):2987-3001.
  • Cover Image

    Cover Image

    issue cover

    Surface rendering of a protein structure of platelet factor 4 (Protein Data Bank code 1RHP) showing the binding regions for antibodies developed in a patient with vaccine-induced immune thrombotic thrombocytopenia (VITT) after Ad26.COV2.S vaccination. The VITT binding site previously described is highlighted in red, and the amino acids of another possible antibody binding site are shown in blue. See the article by Huynh et al.

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