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Issue Archive

Volume 4, Issue 2
January 28 2020
Issue Cover

Table of Contents

CLINICAL GUIDELINES

American Society of Hematology 2020 guidelines for sickle cell disease: transfusion support
Stella T. Chou,Mouaz Alsawas,Ross M. Fasano,Joshua J. Field,Jeanne E. Hendrickson,Jo Howard,Michelle Kameka,Janet L. Kwiatkowski,France Pirenne,Patricia A. Shi,Sean R. Stowell,Swee Lay Thein,Connie M. Westhoff,Trisha E. Wong,Elie A. Akl
View Articletitled, American Society of Hematology 2020 guidelines for sickle cell disease: transfusion support
Supplemental data

STIMULUS REPORTS

P-selectin–deficient mice to study pathophysiology of sickle cell disease
Margaret F. Bennewitz,Egemen Tutuncuoglu,Shweta Gudapati,Tomasz Brzoska,Simon C. Watkins,Satdarshan P. Monga,Tirthadipa Pradhan-Sundd,Prithu Sundd
View Articletitled, P-selectin–deficient mice to study pathophysiology of sickle cell disease
Supplemental data
Efficacy of combined CDK9/BET inhibition in preclinical models of MLL-rearranged acute leukemia
Hannah McCalmont,Ka Leung Li,Luke Jones,John Toubia,Sarah C. Bray,Debora A. Casolari,Chelsea Mayoh,Saumya E. Samaraweera,Ian D. Lewis,Rab K. Prinjha,Nicholas Smithers,Shudong Wang,Richard B. Lock,Richard J. D’Andrea
View Articletitled, Efficacy of combined CDK9/BET inhibition in preclinical models of <em>MLL</em>-rearranged acute leukemia
Supplemental data
Utility of serum free light chain ratio in response definition in patients with multiple myeloma
Clinical Trials & Observations
Nadine Abdallah,Prashant Kapoor,David L. Murray,Francis K. Buadi,David Dingli,Angela Dispenzieri,Morie A. Gertz,Ronald S. Go,Wilson I. Gonsalves,Suzanne R. Hayman,Taxiarchis V. Kourelis,Martha Q. Lacy,Nelson Leung,John A. Lust,Eli Muchtar,Rahma Warsame,Robert A. Kyle,S. Vincent Rajkumar,Shaji K. Kumar
View Articletitled, Utility of serum free light chain ratio in response definition in patients with multiple myeloma

SYSTEMATIC REVIEW

Ruxolitinib for the prevention of thrombosis in polycythemia vera: a systematic review and meta-analysis
Arianna Masciulli,Alberto Ferrari,Alessandra Carobbio,Arianna Ghirardi,Tiziano Barbui
View Articletitled, Ruxolitinib for the prevention of thrombosis in polycythemia vera: a systematic review and meta-analysis
Supplemental data

CLINICAL TRIALS AND OBSERVATIONS

Long-term outcomes after autologous stem cell transplantation for multiple myeloma
Clinical Trials & Observations
Katherine K. Nishimura,Bart Barlogie,Frits van Rhee,Maurizio Zangari,Brian A. Walker,Adam Rosenthal,Carolina Schinke,Sharmilan Thanendrarajan,Faith E. Davies,Antje Hoering,Gareth J. Morgan
View Articletitled, Long-term outcomes after autologous stem cell transplantation for multiple myeloma
Supplemental data

IMMUNOBIOLOGY AND IMMUNOTHERAPY

Evaluation of cyclin A1–specific T cells as a potential treatment for acute myeloid leukemia
Wingchi K. Leung,Aster Workineh,Shivani Mukhi,Ifigeneia Tzannou,Daniel Brenner,Norihiro Watanabe,Ann M. Leen,Premal Lulla
View Articletitled, Evaluation of cyclin A1–specific T cells as a potential treatment for acute myeloid leukemia
Supplemental data

LYMPHOID NEOPLASIA

Outcomes of patients with limited-stage aggressive large B-cell lymphoma with high-risk cytogenetics
Clinical Trials & Observations
Pallawi Torka,Shalin K. Kothari,Suchitra Sundaram,Shaoying Li,L. Jeffrey Medeiros,Emily C. Ayers,Daniel J. Landsburg,David A. Bond,Kami J. Maddocks,Anshu Giri,Brian Hess,Luu Q. Pham,Ranjana Advani,Yang Liu,Stefan Klaus Barta,Julie M. Vose,Michael C. Churnetski,Jonathon B. Cohen,Madelyn Burkart,Reem Karmali,Joanna Zurko,Amitkumar Mehta,Adam J. Olszewski,Sarah Lee,Brian T. Hill,Timothy F. Burns,Frederick Lansigan,Emma Rabinovich,David Peace,Adrienne Groman,Kristopher Attwood,Francisco J. Hernandez-Ilizaliturri
View Articletitled, Outcomes of patients with limited-stage aggressive large B-cell lymphoma with high-risk cytogenetics
BCL-W is dispensable for the sustained survival of select Burkitt lymphoma and diffuse large B-cell lymphoma cell lines
Sarah T. Diepstraten,Catherine Chang,Lin Tai,Jia-nan Gong,Ping Lan,Alexander C. Dowell,Graham S. Taylor,Andreas Strasser,Gemma L. Kelly
View Articletitled, BCL-W is dispensable for the sustained survival of select Burkitt lymphoma and diffuse large B-cell lymphoma cell lines
Supplemental data

MYELOID NEOPLASIA

Clinical and functional significance of circular RNAs in cytogenetically normal AML
Clinical Trials & Observations
Dimitrios Papaioannou,Stefano Volinia,Deedra Nicolet,Michał Świerniak,Andreas Petri,Krzysztof Mrózek,Marius Bill,Felice Pepe,Christopher J. Walker,Allison E. Walker,Andrew J. Carroll,Jessica Kohlschmidt,Ann-Kathrin Eisfeld,Bayard L. Powell,Geoffrey L. Uy,Jonathan E. Kolitz,Eunice S. Wang,Sakari Kauppinen,Adrienne Dorrance,Richard M. Stone,John C. Byrd,Clara D. Bloomfield,Ramiro Garzon
View Articletitled, Clinical and functional significance of circular RNAs in cytogenetically normal AML
Supplemental data
Immune profiles in acute myeloid leukemia bone marrow associate with patient age, T-cell receptor clonality, and survival
Oscar Brück,Olli Dufva,Helena Hohtari,Sami Blom,Riku Turkki,Mette Ilander,Panu Kovanen,Celine Pallaud,Pedro Marques Ramos,Hanna Lähteenmäki,Katja Välimäki,Mohamed El Missiry,Antonio Ribeiro,Olli Kallioniemi,Kimmo Porkka,Teijo Pellinen,Satu Mustjoki
View Articletitled, Immune profiles in acute myeloid leukemia bone marrow associate with patient age, T-cell receptor clonality, and survival
Supplemental data
Early peripheral clearance of leukemia-associated immunophenotypes in AML: centralized analysis of a randomized trial
Clinical Trials & Observations
Giacomo Gianfaldoni,Francesco Mannelli,Tamara Intermesoli,Sara Bencini,Damiano Giupponi,Giorgio Farina,Ilaria Cutini,Maria Ida Bonetti,Arianna Masciulli,Ernesta Audisio,Dario Ferrero,Chiara Pavoni,Anna Maria Scattolin,Alberto Bosi,Alessandro Rambaldi,Renato Bassan
View Articletitled, Early peripheral clearance of leukemia-associated immunophenotypes in AML: centralized analysis of a randomized trial
Supplemental data
N-acetylcysteine inhibits thrombosis in a murine model of myeloproliferative neoplasm
Brianna M. Craver,Gajalakshmi Ramanathan,Summer Hoang,Xinyue Chang,Laura F. Mendez Luque,Stefan Brooks,Hew Yeng Lai,Angela G. Fleischman
View Articletitled, <em>N</em>-acetylcysteine inhibits thrombosis in a murine model of myeloproliferative neoplasm
Supplemental data
Highly multiplexed proteomic assessment of human bone marrow in acute myeloid leukemia
Haydar Çelik,Katherine E. Lindblad,Bogdan Popescu,Gege Gui,Meghali Goswami,Janet Valdez,Christin DeStefano,Catherine Lai,Julie Thompson,Jack Y. Ghannam,Giovanna Fantoni,Angélique Biancotto,Julián Candia,Foo Cheung,Gauthaman Sukumar,Clifton L. Dalgard,Richard H. Smith,Andre Larochelle,Laura W. Dillon,Christopher S. Hourigan
View Articletitled, Highly multiplexed proteomic assessment of human bone marrow in acute myeloid leukemia
Supplemental data

THROMBOSIS AND HEMOSTASIS

von Willebrand factor/ADAMTS13 ratio at presentation of acute ischemic brain injury is predictive of outcome
Clinical Trials & Observations
Alice Taylor,Chiara Vendramin,Deepak Singh,Martin M. Brown,Marie Scully
View Articletitled, von Willebrand factor/ADAMTS13 ratio at presentation of acute ischemic brain injury is predictive of outcome
Supplemental data
Bleeding and recurrent VTE with apixaban vs warfarin as outpatient treatment: time-course and subgroup analyses
Derek Weycker,Gail DeVecchis Wygant,Jennifer D. Guo,Theodore Lee,Xuemei Luo,Lisa Rosenblatt,Jack Mardekian,Mark Atwood,Ahuva Hanau,Alexander T. Cohen
View Articletitled, Bleeding and recurrent VTE with apixaban vs warfarin as outpatient treatment: time-course and subgroup analyses
Supplemental data

TRANSFUSION MEDICINE

Recapitulation of posttransfusion purpura by cross-strain platelet immunization in mice
Daniel W. Bougie,Jessica Sutton,Richard H. Aster
View Articletitled, Recapitulation of posttransfusion purpura by cross-strain platelet immunization in mice
Supplemental data

TRANSPLANTATION

Impact of graft sources on immune reconstitution and survival outcomes following allogeneic stem cell transplantation
Clinical Trials & Observations
Taiki Ando,Takayoshi Tachibana,Masatsugu Tanaka,Taisei Suzuki,Yasufumi Ishiyama,Satoshi Koyama,Eriko Ogusa,Ayumi Numata,Kenji Matsumoto,Heiwa Kanamori,Hideaki Nakajima
View Articletitled, Impact of graft sources on immune reconstitution and survival outcomes following allogeneic stem cell transplantation
Supplemental data

COMMENTARIES

Sex differences in the trajectory of glomerular filtration rate in pediatric and murine sickle cell anemia
Malgorzata Kasztan,Inmaculada Aban,Suraj P. Hande,David M. Pollock,Jeffrey D. Lebensburger
View Articletitled, Sex differences in the trajectory of glomerular filtration rate in pediatric and murine sickle cell anemia
Response to “Missed diagnosis and misdiagnosis of infectious diseases in hematopoietic cell transplant recipients: an autopsy study”
Clinical Trials & Observations
Dionysios Neofytos,Genovefa Papanicolaou
View Articletitled, Response to “Missed diagnosis and misdiagnosis of infectious diseases in hematopoietic cell transplant recipients: an autopsy study”

ERRATUM

Neunert C, Terrell DR, Arnold DM, et al. American Society of Hematology 2019 guidelines for immune thrombocytopenia. Blood Adv. 2019;3(23):3829-3866.
View Articletitled, Neunert C, Terrell DR, Arnold DM, et al. American Society of Hematology 2019 guidelines for immune thrombocytopenia. <em>Blood Adv.</em> 2019;3(23):3829-3866.
  • Cover Image

    Cover Image

    issue cover

    COVER FIGURE
    Quantitative fluorescence intravital lung microscopy (qFILM) image reveals an absence of lung vaso-occlusion in a P-selectin–deficient sickle cell disease (SS-Selp-/-) mouse intravenously administered 0.1 µg/kg lipopolysaccharide. A neutrophil (marked by the dotted circle) is trafficking through the pulmonary arteriole. Pulmonary microcirculation is shown in purple, neutrophils in red, and platelets in green. The white arrow denotes the direction of blood flow. Alveoli are visible as dark regions. See the article by Bennewitz et al.

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