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Volume 1, Issue 27

December 26 2017

In this Issue

EXCEPTIONAL CASE REPORT
GENE THERAPY
HEMATOPOIESIS AND STEM CELLS
IMMUNOBIOLOGY AND IMMUNOTHERAPY
LYMPHOID NEOPLASIA
MYELOID NEOPLASIA
RED CELLS, IRON, AND ERYTHROPOIESIS
THROMBOSIS AND HEMOSTASIS
TRANSFUSION MEDICINE
TRANSPLANTATION

EXCEPTIONAL CASE REPORT

T-cell prolymphocytic leukemia in an adolescent with ataxia-telangiectasia: novel approach with a JAK3 inhibitor (tofacitinib)
Clinical Trials & Observations

Geling Li,Emily Waite,Julie Wolfson

View Articletitled, T-cell prolymphocytic leukemia in an adolescent with ataxia-telangiectasia: novel approach with a JAK3 inhibitor (tofacitinib)

GENE THERAPY

Gene transfer into hematopoietic stem cells reduces HLH manifestations in a murine model of Munc13-4 deficiency

Tayebeh Soheili,Amandine Durand,Fernando E. Sepulveda,Julie Rivière,Chantal Lagresle-Peyrou,Hanem Sadek,Geneviève de Saint Basile,Samia Martin,Fulvio Mavilio,Marina Cavazzana,Isabelle André-Schmutz

View Articletitled, Gene transfer into hematopoietic stem cells reduces HLH manifestations in a murine model of Munc13-4 deficiency

HEMATOPOIESIS AND STEM CELLS

Not just a marker: CD34 on human hematopoietic stem/progenitor cells dominates vascular selectin binding along with CD44

Dina B. AbuSamra,Fajr A. Aleisa,Asma S. Al-Amoodi,Heba M. Jalal Ahmed,Chee Jia Chin,Ayman F. Abuelela,Ptissam Bergam,Rachid Sougrat,Jasmeen S. Merzaban

View Articletitled, Not just a marker: CD34 on human hematopoietic stem/progenitor cells dominates vascular selectin binding along with CD44

Supplemental data

IMMUNOBIOLOGY AND IMMUNOTHERAPY

Interleukins 12 and 15 induce cytotoxicity and early NK-cell differentiation in type 3 innate lymphoid cells

Ana Raykova,Paolo Carrega,Frank M. Lehmann,Robert Ivanek,Vanessa Landtwing,Isaak Quast,Jan D. Lünemann,Daniela Finke,Guido Ferlazzo,Obinna Chijioke,Christian Münz

View Articletitled, Interleukins 12 and 15 induce cytotoxicity and early NK-cell differentiation in type 3 innate lymphoid cells

Supplemental data

The oncogenic membrane protein LMP1 sequesters TRAF3 in B-cell lymphoma cells to produce functional TRAF3 deficiency

Pradeep Bangalore-Prakash,Laura L. Stunz,Nurbek Mambetsariev,Amy L. Whillock,Bruce S. Hostager,Gail A. Bishop

View Articletitled, The oncogenic membrane protein LMP1 sequesters TRAF3 in B-cell lymphoma cells to produce functional TRAF3 deficiency

Replacing mouse BAFF with human BAFF does not improve B-cell maturation in hematopoietic humanized mice

Julie Lang,Bicheng Zhang,Margot Kelly,Jacob N. Peterson,Jacob Barbee,Brian M. Freed,James P. Di Santo,Jennifer L. Matsuda,Raul M. Torres,Roberta Pelanda

View Articletitled, Replacing mouse BAFF with human BAFF does not improve B-cell maturation in hematopoietic humanized mice

Supplemental data

LYMPHOID NEOPLASIA

Hypoxia promotes IL-32 expression in myeloma cells, and high expression is associated with poor survival and bone loss

Muhammad Zahoor,Marita Westhrin,Kristin Roseth Aass,Siv Helen Moen,Kristine Misund,Katarzyna Maria Psonka-Antonczyk,Mariaserena Giliberto,Glenn Buene,Anders Sundan,Anders Waage,Anne-Marit Sponaas,Therese Standal

View Articletitled, Hypoxia promotes IL-32 expression in myeloma cells, and high expression is associated with poor survival and bone loss

Supplemental data

MYELOID NEOPLASIA

Bone disease in monoclonal gammopathy of undetermined significance: results from a screened population-based study
Clinical Trials & Observations

Sigrun Thorsteinsdottir,Sigrun H. Lund,Ebba K. Lindqvist,Marianna Thordardottir,Gunnar Sigurdsson,Rene Costello,Debra Burton,Hlif Steingrimsdottir,Vilmundur Gudnason,Gudny Eiriksdottir,Kristin Siggeirsdottir,Tamara B. Harris,Ola Landgren,Sigurdur Y. Kristinsson

View Articletitled, Bone disease in monoclonal gammopathy of undetermined significance: results from a screened population-based study

RED CELLS, IRON, AND ERYTHROPOIESIS

Standard measures for sickle cell disease research: the PhenX Toolkit sickle cell disease collections

James R. Eckman,Kathryn L. Hassell,Wayne Huggins,Ellen M. Werner,Elizabeth S. Klings,Robert J. Adams,Julie A. Panepinto,Carol M. Hamilton

View Articletitled, Standard measures for sickle cell disease research: the PhenX Toolkit sickle cell disease collections

Red blood cell metabolism in Down syndrome: hints on metabolic derangements in aging

Rachel Culp-Hill,Connie Zheng,Julie A. Reisz,Keith Smith,Angela Rachubinski,Travis Nemkov,Eric Butcher,Ross Granrath,Kirk C. Hansen,Joaquín M. Espinosa,Angelo D’Alessandro

View Articletitled, Red blood cell metabolism in Down syndrome: hints on metabolic derangements in aging

Supplemental data

THROMBOSIS AND HEMOSTASIS

TFPIα interacts with FVa and FXa to inhibit prothrombinase during the initiation of coagulation

Jeremy P. Wood,Helle H. Petersen,Bingke Yu,Xiaoai Wu,Ida Hilden,Alan E. Mast

View Articletitled, TFPIα interacts with FVa and FXa to inhibit prothrombinase during the initiation of coagulation

Supplemental data

Coordination of platelet agonist signaling during the hemostatic response in vivo

Jian Shen,Sara Sampietro,Jie Wu,Juan Tang,Shuchi Gupta,Chelsea N. Matzko,Chaojun Tang,Ying Yu,Lawrence F. Brass,Li Zhu,Timothy J. Stalker

View Articletitled, Coordination of platelet agonist signaling during the hemostatic response in vivo

Supplemental data

TRANSFUSION MEDICINE

ABO blood group A transferases catalyze the biosynthesis of FORS blood group FORS1 antigen upon deletion of exon 3 or 4

Miyako Yamamoto,Emili Cid,Fumiichiro Yamamoto

View Articletitled, ABO blood group A transferases catalyze the biosynthesis of FORS blood group FORS1 antigen upon deletion of exon 3 or 4

Supplemental data

TRANSPLANTATION

Identification of a murine CD45⁻F4/80^lo HSC-derived marrow endosteal cell associated with donor stem cell engraftment

Kathleen M. Overholt,Satoru Otsuru,Timothy S. Olson,Adam J. Guess,Victoria M. Velazquez,Laura Desbourdes,Massimo Dominici,Edwin M. Horwitz

View Articletitled, Identification of a murine CD45<sup>−</sup>F4/80<sup>lo</sup> HSC-derived marrow endosteal cell associated with donor stem cell engraftment

Supplemental data

Evolution, trends, outcomes, and economics of hematopoietic stem cell transplantation in severe autoimmune diseases
Clinical Trials & Observations

John A. Snowden,Manuela Badoglio,Myriam Labopin,Sebastian Giebel,Eoin McGrath,Zora Marjanovic,Joachim Burman,John Moore,Montserrat Rovira,Nico M. Wulffraat,Majid Kazmi,Raffaella Greco,Emilian Snarski,Tomas Kozak,Kirill Kirgizov,Tobias Alexander,Peter Bader,Riccardo Saccardi,Dominique Farge,for the European Society for Blood and Marrow Transplantation (EBMT) Autoimmune Diseases Working Party (ADWP), EBMT Paediatric Working Party (PWP), and the Joint Accreditation Committee of the International Society for Cellular Therapy (ISCT) and EBMT (JACIE)

View Articletitled, Evolution, trends, outcomes, and economics of hematopoietic stem cell transplantation in severe autoimmune diseases

Supplemental data

Cover Image

Cover Image

COVER FIGURE
Newly identified hematopoietic stem cell–derived marrow endosteal cell (red cell) characterized as CD45⁻F4/80^lo residing amongst osteoblasts in murine bone marrow. See the article by Overholt et al.
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Table of Contents

EXCEPTIONAL CASE REPORT

T-cell prolymphocytic leukemia in an adolescent with ataxia-telangiectasia: novel approach with a JAK3 inhibitor (tofacitinib)
Clinical Trials & Observations

GENE THERAPY

Gene transfer into hematopoietic stem cells reduces HLH manifestations in a murine model of Munc13-4 deficiency

HEMATOPOIESIS AND STEM CELLS

Not just a marker: CD34 on human hematopoietic stem/progenitor cells dominates vascular selectin binding along with CD44

IMMUNOBIOLOGY AND IMMUNOTHERAPY

Interleukins 12 and 15 induce cytotoxicity and early NK-cell differentiation in type 3 innate lymphoid cells

The oncogenic membrane protein LMP1 sequesters TRAF3 in B-cell lymphoma cells to produce functional TRAF3 deficiency

Replacing mouse BAFF with human BAFF does not improve B-cell maturation in hematopoietic humanized mice

LYMPHOID NEOPLASIA

Hypoxia promotes IL-32 expression in myeloma cells, and high expression is associated with poor survival and bone loss

MYELOID NEOPLASIA

Bone disease in monoclonal gammopathy of undetermined significance: results from a screened population-based study
Clinical Trials & Observations

RED CELLS, IRON, AND ERYTHROPOIESIS

Standard measures for sickle cell disease research: the PhenX Toolkit sickle cell disease collections

Red blood cell metabolism in Down syndrome: hints on metabolic derangements in aging

THROMBOSIS AND HEMOSTASIS

TFPIα interacts with FVa and FXa to inhibit prothrombinase during the initiation of coagulation

Coordination of platelet agonist signaling during the hemostatic response in vivo

TRANSFUSION MEDICINE

ABO blood group A transferases catalyze the biosynthesis of FORS blood group FORS1 antigen upon deletion of exon 3 or 4

TRANSPLANTATION

Identification of a murine CD45⁻F4/80^lo HSC-derived marrow endosteal cell associated with donor stem cell engraftment

Evolution, trends, outcomes, and economics of hematopoietic stem cell transplantation in severe autoimmune diseases
Clinical Trials & Observations

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ASH Publications

American Society of Hematology

Issue Archive

Table of Contents

EXCEPTIONAL CASE REPORT

T-cell prolymphocytic leukemia in an adolescent with ataxia-telangiectasia: novel approach with a JAK3 inhibitor (tofacitinib) Clinical Trials & Observations

GENE THERAPY

HEMATOPOIESIS AND STEM CELLS

IMMUNOBIOLOGY AND IMMUNOTHERAPY

LYMPHOID NEOPLASIA

MYELOID NEOPLASIA

Bone disease in monoclonal gammopathy of undetermined significance: results from a screened population-based study Clinical Trials & Observations

RED CELLS, IRON, AND ERYTHROPOIESIS

THROMBOSIS AND HEMOSTASIS

TRANSFUSION MEDICINE

TRANSPLANTATION

Evolution, trends, outcomes, and economics of hematopoietic stem cell transplantation in severe autoimmune diseases Clinical Trials & Observations

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Email alerts

ASH Publications

American Society of Hematology

This Feature Is Available To Subscribers Only

T-cell prolymphocytic leukemia in an adolescent with ataxia-telangiectasia: novel approach with a JAK3 inhibitor (tofacitinib)
Clinical Trials & Observations

Bone disease in monoclonal gammopathy of undetermined significance: results from a screened population-based study
Clinical Trials & Observations

Evolution, trends, outcomes, and economics of hematopoietic stem cell transplantation in severe autoimmune diseases
Clinical Trials & Observations