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Journal Articles

Tumor-targeted nanoparticles improve the therapeutic index of BCL2 and MCL1 dual inhibition

Free
Neeta Bala Tannan, Mandana T. Manzari, Laurie Herviou, Mariana Da Silva Ferreira, Connor Hagen, Hiroto Kiguchi, Katia Manova-Todorova, Venkatraman Seshan, Elisa de Stanchina, Daniel A. Heller, Anas Younes
Journal: Blood
Blood (2021) 137 (15): 2057–2069.
https://doi.org/10.1182/blood.2020008017
Published: 2021
Includes: Supplemental data
Journal Articles

Pharmacologic Normalization of Altered Transcriptome of SF3B1 Mutant Myeloid Neoplasia

Free
Valeria Visconte, PhD, Vera Adema, PhD, Anand D. Tiwari, PhD, Cassandra M Kerr, MS, Hassan Awada, Bartlomiej Przychodzen, Allison Noe, Rachel Toth, Christina Snider, Yvonne Parker, Yuriy Fedorov, Drew Adams, Hetty E. Carraway, MD MBA, Anjali S. Advani, MD, Kevin R Kelly, MD PhD, Steffan T. Nawrocki, PhD, Jennifer S. Carew, PhD, Heesun J. Rogers, MD PhD, Daniel J. Lindner, Mikkael A. Sekeres, MD MS, James G Phillips, PhD, Jaroslaw P. Maciejewski, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 564.
https://doi.org/10.1182/blood-2019-129189
Published: 2019
Journal Articles

Pharmacological Inhibition of the RNA m 6 a Writer METTL3 As a Novel Therapeutic Strategy for Acute Myeloid Leukemia

Free
Konstantinos Tzelepis, Etienne De Braekeleer, PhD MSc, Eliza Yankova, PhD, Justyna Rak, PhD, Demetrios Aspris, MSc, Ana Filipa Domingues, PhD, Richard Fosbeary, Alan Hendrick, PhD, Dan Leggate, PhD, Yaara Ofir-Rosenfeld, PhD, Alexandra Sapetschnig, PhD, Cristina Pina, MDDPhil, Mark Albertella, PhD, Wesley Blackaby, PhD, Oliver Rausch, PhD, George S. Vassiliou, FRCPath, MRCP, PhD, Tony Kouzarides, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 403.
https://doi.org/10.1182/blood-2019-127962
Published: 2019
Journal Articles

Understanding the Mechanisms Underlying Thrombocytopenia in Visceral Leishmaniasis

Free
Gulab Fatima Rani, MBBS, Olivier Preham, PhD, Ian Hitchcock, PhD, Paul Kaye, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 2378.
https://doi.org/10.1182/blood-2019-128133
Published: 2019
Journal Articles

Efficacy and Safety of Direct Oral Factor Xa Inhibitors in Patients after Bariatric Surgery

Free
Margarita Kushnir, MD, Radhika Gali, MD, Mariam Alexander, MD, Henny Heisler H. Billett, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 2439.
https://doi.org/10.1182/blood-2019-127645
Published: 2019
Journal Articles

Real-World Utilization of Midostaurin Among Patients with Systemic Mastocytosis (SM)

Free
Ajeet Gajra, MD FACP, Andrew J Klink, PhD MPH, Dhruv Chopra, MS, Bruce Feinberg, DO
Journal: Blood
Blood (2019) 134 (Supplement_1): 5378.
https://doi.org/10.1182/blood-2019-131028
Published: 2019
Journal Articles

Symptom Assessment in Patients with BCR-ABL-Negative Myeloproliferative Neoplasms at an Academic Medical Institution

Free
Kelly L. Schoenbeck, MD, Miguel Carlos Cerejo, DO, Patricia A. Cornett, MD, Lloyd E. Damon, MD, Karin L. Gaensler, MD, Andrew D. Leavitt, MD, Aaron C. Logan, MD PhD, Gabriel N. Mannis, MD, Rebecca L. Olin, MD, Giselle Salmasi, MD, Peter H. Sayre, MD PhD, Neil P. Shah, MD PhD, Anand Dhruva, MD, Chloe E. Atreya, MD PhD, Catherine C. Smith, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 5859.
https://doi.org/10.1182/blood-2019-129638
Published: 2019
Journal Articles

Impact and Safety of Chimeric Antigen Receptor T Cell Therapy in Vulnerable Older Patients with Relapsed/Refractory Diffuse Large B-Cell Lymphoma

Free
Richard J Lin, MD PhD, Stephanie M Lobaugh, MS, Martina Pennisi, Jason T Chan, RN, Yakup Batlevi, PhD, Josel D Ruiz, MPH, Theresa A Elko, MS, Molly A. Maloy, MS, Connie Lee Batlevi, MD PhD, Parastoo B. Dahi, MD, Sergio A Giralt, MD, Elena Mead, MD, Ariela Noy, MD, Maria Lia Palomba, MD, Bianca Santomasso, MD PhD, Craig S. Sauter, MD, Michael Scordo, MD, Gunjan L. Shah, MD, Beatriz Korc-Grodzicki, MD PhD, Soo Jung Kim, NP, Mari Lynne Silverberg, Chelsea A Brooklyn, Sean M. Devlin, PhD, Miguel-Angel Perales, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 1603.
https://doi.org/10.1182/blood-2019-125162
Published: 2019
Journal Articles

Proteomic Profiling and Mechanistic Investigating of a Novel Anti-Cancer Small Molecule Inhibitor of Sec61

Free
Yu Qian, PhD, Henry W.B. Johnson, PhD, Christopher J. Kirk, PhD, Eric Lowe, BS, Dustin McMinn, PhD, Beatriz Millare, BS, Tony Muchamuel, MS, Jinhai Wang, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 2076.
https://doi.org/10.1182/blood-2019-125988
Published: 2019
Journal Articles

Inhibiting Mitochondria Function By Bcl-2 Inhibitor Venetoclax and Complex I Inhibitor Iacs-010759 Eliminate Leukemia Cells in Pre-Clinical AML Models

Free
Qi Zhang, PhD, Alessia Lodi, PhD, Shannon Renee Sweeney, PhD, Lina Han, PhD, Tianyu Cai, PhD, Vinitha Mary Kuruvilla, MSc, Antonio Cavazos, Helen Ma, MS, Yoko Tabe, MD PhD, Joseph R Marszalek, PhD, Stefano Tiziani, PhD, Marina Y Konopleva, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 3927.
https://doi.org/10.1182/blood-2019-124494
Published: 2019
Journal Articles

Pediatric Preclinical Testing Consortium Evaluation of the Novel Anti-Microtubule Drug E7130 in Xenograft Models of Early T-Cell Precursor Acute Lymphoblastic Leukemia

Free
Richard B. Lock, PhD, Kathryn Evans, Connor D Jones, Narimanne El-Zein, Katerina Bendak, PhD, Cara E Toscan, PhD, Chelsea Mayoh, Stephen W Erickson, PhD, Beverly A Teicher, PhD, Malcolm A Smith, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 3875.
https://doi.org/10.1182/blood-2019-123867
Published: 2019
Journal Articles

Targeted Delivery of Nanocarrier-Conjugated Doxorubicin to Widen the Therapeutic Window of the Most Active Drug in Lymphoma Therapeutics

Free
Artavazd Arumov, BSc, Piumi Y. Liyanage, BS, Asaad Trabolsi, MD, Lingxiao Li, PhD, Evan R. Roberts, BS, Daniel Bilbao, PhD, Roger M. LeBlanc, PhD, Jonathan H. Schatz, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 4061.
https://doi.org/10.1182/blood-2019-122599
Published: 2019
Journal Articles

Development of a Sensitive and Efficient Reporter Platform for the Detection of Chimeric Antigen Receptor T Cell Expansion, Trafficking, and Toxicity

Free
Reona Sakemura, MD PhD, Lukkana Suksanpaisan, PhD, Roman H Khadka, Alysha N Newsom, Michael J. Hansen, Michelle J. Cox, Mehrdad Hefazi, MD, Claudia Manriquez Roman, Kendall J. Schick, Erin E. Tapper, Paulina Roman Moreno, MD, Michael W. Ruff, MD, Sameer A. Parikh, MD, Neil E. Kay, MD, Kah-Whye Peng, PhD, Stephen J Russell, MD PhD, Saad S. Kenderian, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 53.
https://doi.org/10.1182/blood-2019-123476
Published: 2019
Journal Articles

Selinexor Combined with Ibrutinib Demonstrates Tolerability and Efficacy in Advanced B-Cell Malignancies: A Phase I Study

Free
Deborah M. Stephens, DO, Ying Huang, MS, MA, Akwasi Agyeman, Amy S. Ruppert, MAS, PhD, Boyu Hu, MD, Natalie Turner, APRN, Renee Vadeboncoeur, MSN, APRN, Kerry A Rogers, MD, Seema A. Bhat, MD, Basem M. William, MRCP,MD, Samantha Jaglowski, MDMPH, Hank Lockman, Martha Glenn, MD, Rosa Lapalombella, PhD, John C. Byrd, MD, Jennifer Woyach, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 4310.
https://doi.org/10.1182/blood-2019-124544
Published: 2019
Journal Articles

The Use of Placenta-Derived Decidua Stromal Cells for Treatment of Severe Acute Gastrointestinal Graft-Versus-Host-Disease in Adults and Children

Free
Sadeghi Behnam, PhD MD, Remberger Mats, PhD, Per Frisk, MD PhD, Britt-Marie Frost, MD PhD, Olle Ringden, Professor, Britt Gustafsson, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 4456.
https://doi.org/10.1182/blood-2019-122674
Published: 2019
Journal Articles

Poor-Risk AML with Complex, Monosomal Karyotype: In Vivo Therapeutic Efficacy of Decitabine (DAC) in Patient-Derived Xenograft (PDX) Mouse Models

Free
Gabriele Greve, PhD, Julia Schüler, DVM, Eva Oswald, PhD, Michael Lübbert
Journal: Blood
Blood (2019) 134 (Supplement_1): 2644.
https://doi.org/10.1182/blood-2019-126514
Published: 2019
Journal Articles

Urine Proteomic Analysis Reveals Disease-Specific Patterns in Pediatric Patients with Classical Hodgkin's Disease(HD). an Addon Study to the Euronet-PHL-C2 Trial

Free
Karl-Walter Sykora, MD, Jochen Metzger, PhD, Dieter Körholz, MD PhD, Michael Frühwald, MD, Gabriele Strauss, MD, Norbert Jorch, MD, Jozef Zlocha, MD PhD, Thomas Wiesel, MD, Axel Sauerbrey, MD, Monika Streiter, MD, Rhoikos Furtwaengler, MD, Gunnar Cario, MD PhD, Thorsten Simon, MD PhD, Holger Christiansen, MD, Peter Vorwerk, MD, Angela Wawer, MD, Wolfram Scheurlen, MD, Hermann Müller, MD, Stefan Bielack, MD, Martin Ebinger, PD Dr. MD, Klaus-Michael Debatin, MD, Oliver Andres, MD, Christine Mauz-Körholz, Anja Troeger, MD, Dominik Schneider, MD, Eva M Weissinger, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 2804.
https://doi.org/10.1182/blood-2019-125611
Published: 2019
Journal Articles

Cachexia at Diagnosis adversely predicts outcomes in patients with Aggressive B-Cell NHL receiving standard of care treatment: A Prospective Observational Study from India

Free
Vivek S Radhakrishnan, MDDM,MSc, Reena Nair, MD, Anwesha Patra, Saurabh Jayant Bhave, MD, Jeevan Kumar Garg, MDDNB, Mohandas Mallath, MDDNB
Journal: Blood
Blood (2019) 134 (Supplement_1): 2907.
https://doi.org/10.1182/blood-2019-126295
Published: 2019
Journal Articles

Characteristics of Serum Lipidome in Patients with POEMS Syndrome

Free
Hao Zhao, MD, Xue-min Gao, Xinxin Cao, MD, Lu Zhang, MD, Dao-Bin Zhou, Jian Li, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 3082.
https://doi.org/10.1182/blood-2019-122239
Published: 2019
Journal Articles

Safety and Efficacy of the Combination of Selinexor, Lenalidomide and Dexamethasone (SRd) in Patients with Newly Diagnosed Multiple Myeloma

Free
Darrell J White, MD, Suzanne Lentzsch, MD PhD, Cristina Gasparetto, MD, Nizar Bahlis, MD, Christine I Chen, MD, Brea C. Lipe, MD, Gary J. Schiller, MD, Sascha A Tuchman, MD, Heather J. Sutherland, MD PhD, Rami Kotb, MD, Richard Leblanc, MDFRCPC, Michael Sebag, MD PhD, Christopher P Venner, MD, Natalie Scott Callander, MD, William I. Bensinger, Heidi Sheehan, Yi Chai, Kazuharu Kai, MD, Jatin Shah, MD, Sharon Shacham, PhD MBA, Michael G. Kauffman, MD PhD, Muhamed Baljevic, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 3165.
https://doi.org/10.1182/blood-2019-124370
Published: 2019