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Journal Articles

A fully human anti-BMP6 antibody reduces the need for erythropoietin in rodent models of the anemia of chronic disease

Blood (2020) 136 (9): 1080–1090.

https://doi.org/10.1182/blood.2019004653

Published: 2020

Includes: Supplemental data

Journal Articles

Role of MMP-13 in Graft-Versus-Host Disease

Hui-Hui Ma, PhD, Jing Fu, PhD, Suzanne Lentzsch, MD PhD, Markus Y Mapara, MD PhD

Blood (2019) 134 (Supplement_1): 1928.

https://doi.org/10.1182/blood-2019-127703

Published: 2019

Journal Articles

Next-Generation FVIII Mimetic Shows Superior Effect in a FIX- and Fx-Humanized Mouse Model In Vivo

Carsten Dan Ley, PhD, Thomas Lindebo Holm, PhD, Daniel Elenius, PhD, Heidi Lindgreen Holmberg, PhD, Jais Rose Bjelke, PhD, Mette Loftager, PhD, Mette B Hermit, PhD, Ida Hilden, Stine L Kjellev, PhDDVM

Blood (2019) 134 (Supplement_1): 3631.

https://doi.org/10.1182/blood-2019-128159

Published: 2019

Journal Articles

Exploitation of a Newly Characterized Metabolic-Cytoskeletal Axis for Effective Combination Therapy of Iron Restricted Anemia

Adam N Goldfarb, MD, Katie Freeman, BA, Alejandro Ariel Gru, MD, Zollie White, III, MS, Lorrie L Delehanty, BS

Blood (2019) 134 (Supplement_1): 2233.

https://doi.org/10.1182/blood-2019-129172

Published: 2019

Journal Articles

A Phase 1 a/b Dose Escalation Trial to Evaluate the Safety and Tolerability of CG-806 in Patients with Relapsed or Refractory CLL/SLL or Non-Hodgkin's Lymphomas

Stephen B Howell, MD, Hongying Zhang, MD PhD, William G Rice, PhD

Blood (2019) 134 (Supplement_1): 5477.

https://doi.org/10.1182/blood-2019-130784

Published: 2019

Journal Articles

Preclinical Development of a Bcma Targeting Antibody-Drug Conjugate with Novel Payload for Multiple Myeloma Therapy

Andrew Hau, PhD, Tong Zhu, PhD, Rengang Wang, PhD, Megan Lau, BS, Lingna Li, PhD, Xiaoqing Li, PhD, Yingqing Sun, PhD, Ernest Kovacs, PhD, Alisher Khasanov, PhD, Dalun Deng, PhD, Zheng Yan, PhD, Robert D. Knight, MD, Gunnar F. Kaufmann, PhD, Henry Ji, PhD, Hui Li, PhD, Hong Zhang, PhD

Blood (2019) 134 (Supplement_1): 5623.

https://doi.org/10.1182/blood-2019-132080

Published: 2019

Journal Articles

SE-7552, a Highly Selective, Non-Hydroxamate Inhibitor of Histone Deacetylase-6 Blocks Multiple Myeloma Growth In Vivo

Jason A Holt, MSc, Edward P Garvey, PhD, J. David Becherer, PhD, William J Hoekstra, PhD, Robert J Schotzinger, MD PhD, Christopher M Yates, MSc

Blood (2018) 132 (Supplement 1): 3215.

https://doi.org/10.1182/blood-2018-99-113066

Published: 2018

Journal Articles

Novel Insights Into Systemic Iron Regulation

Laura Silvestri, PhD, Alessia Pagani, PhD, Antonella Nai, PhD, Clara Camaschella, MD

Blood (2018) 132 (Supplement 1): SCI-1.

https://doi.org/10.1182/blood-2018-99-109518

Published: 2018

Journal Articles

Hepcidin Suppression By Momelotinib Is Associated with Increased Iron Availability and Erythropoiesis in Transfusion-Dependent Myelofibrosis Patients

Stephen T Oh, MD PhD, Moshe Talpaz, MD, Aaron T. Gerds, MDMS, Vikas Gupta, MD FRCP, FRCPath, Srdan Verstovsek, MD PhD, Ruben A. Mesa, MD FACP, Carole Brennan Miller, MD, Candido E. Rivera, MD, Angela Fleischman, MD PhD, Swati Goel, Mark L Heaney, MD PhD, Casey O'Connell, MD, Murat Arcasoy, MD, Yafeng Zhang, PhD MD, Jun Kawashima, MD, Tomas Ganz, MD PhD, Carrie Baker Brachmann

Blood (2018) 132 (Supplement 1): 4282.

https://doi.org/10.1182/blood-2018-99-111349

Published: 2018

Journal Articles

Prospective, Multi-Center, Phase I Clinical Trial of PLX-R18 Placental Expanded Adherent Stromal Cells in Subjects with Incomplete Hematopoietic Recovery after Hematopoietic Cell Transplantation

Hillard M Lazarus, MD, Leland Metheny, MD, Tsila Zuckerman, MD, Carolina Escobar, MD, Joseph P. McGuirk, DO, Yael Rosen, MD, Jacob M. Rowe, MD

Blood (2018) 132 (Supplement 1): 3379.

https://doi.org/10.1182/blood-2018-99-116239

Published: 2018

Journal Articles

SLN124, a Galnac-siRNA Conjugate Targeting TMPRSS6, for the Treatment of Iron Overload and Ineffective Erythropoiesis Such As in Beta-Thalassemia

Sandro Altamura, PhD, Sandro Altamura, PhD, Martina U. Muckenthaler, PhD, Sibylle Dames, MSc, Christian Frauendorf, PhD, Steffen Schubert, PhD, Manuela Aleku, MSc, Jim Vadolas, PhD, George Grigoriadis, MBBS PhD FRACP FRCPA, Ulrich Zügel, PhD

Blood (2018) 132 (Supplement 1): 2340.

https://doi.org/10.1182/blood-2018-99-110163

Published: 2018

Journal Articles

The Hypofibrinolytic Defect of Nephrotic Syndrome Is Directly Proportional to Fibrin Network Density

Amanda P. Waller, PhD, Katelyn J Wolfgang, Bryce A. Kerlin, MD

Blood (2018) 132 (Supplement 1): 1218.

https://doi.org/10.1182/blood-2018-99-119947

Published: 2018

Journal Articles

Genetic Evidence for Involvement of Human Endogenous Retrovirus Herv-Fc1 in the Pathogenesis of MPNs

Vibe Skov, PhD, Katrine LM Schmidt, Kasper Mønsted Pedersen, MD, Bettina Hansen, Tobias Wirenfeldt Klausen, M.S., Torben A Kruse, Mads Thomassen, PhD, Lasse Kjær, PhD, Christina Ellervik, Associate Professor, MD PhD, Morten Holmstrøm, MD, Bjørn Nexø, Hans Carl Hasselbalch, Professor, dr.MD, Magdalena J Laska

Blood (2018) 132 (Supplement 1): 5488.

https://doi.org/10.1182/blood-2018-99-118080

Published: 2018

Journal Articles

A Fully Human Anti-BMP6 Antibody Reduces the Need for Erythropoietin Stimulating Agent in Two Rodent Anemia of Chronic Disease Models

Verena Petzer, MD, Piotr Tymoszuk, PhD, Matthew Wake, PhD, Luke Bayliss, BSc, Jonathan Papworth, BSc, Joana Carvalho, PhD, Cecilia Deantonio, PhD, Malte Ferdinand Asshoff, MD, Markus Seifert, Sylvia Berger, Dominik Wolf, MD, Günter Weiss, MD, Volker Germaschewski, PhD, Igor Theurl, MD PhD

Blood (2018) 132 (Supplement 1): 1045.

https://doi.org/10.1182/blood-2018-99-115747

Published: 2018

Journal Articles

Absence of Plasma Gastric Biomarker Elevations with Chronic Dosing of Avatrombopag, a Novel Oral Thrombopoietin Receptor Agonist, in Patients with Chronic Immune Thrombocytopenia in Phase 3 Trials

James B. Bussel, MD, Lee F. Allen, MD PhD, Wei Tian, PhD, David J. Kuter, MD DPhil

Blood (2018) 132 (Supplement 1): 3740.

https://doi.org/10.1182/blood-2018-99-116873

Published: 2018

Journal Articles

A Transient Induction of Blood-Circulating Bile Acid Is a Therapeutic Marker and Target of Chemotherapy-Oriented Myelosuppression

Valgardur Sigurdsson, PhD, Youichi Haga, MD PhD, Hajime Takei, PhD, Chizuko Okamatsu-Haga, MD PhD, Visnja Radulovic, PhD, Mark Van Der Garde, PhD, Mitsuyoshi Suzuki, MD PhD, Svetlana Soboleva, Hiroshi Nittono, MD PhD, Akira Ohara, MD, Kenichi Miharada, PhD

Blood (2017) 130 (Supplement 1): 3344.

https://doi.org/10.1182/blood.V130.Suppl_1.3344.3344

Published: 2017

Journal Articles

Vitamin D Relation to Busulphan in Pediatrics Undergoing Hematopoietic Stem Cell Transplantation

Fadwa Benkessou, MSc, Moustapha Hassan, PhD, Ibrahim El serafi, PhD, Ahmed El serafi, PhD, Wenyi Zheng, Manuchehr Abedi-Valugerdi, PhD, Jonas Mattsson, MD PhD, Martin Höglund, MD PhD, Karin Mellgren, MD PhD

Blood (2017) 130 (Supplement 1): 5481.

https://doi.org/10.1182/blood.V130.Suppl_1.5481.5481

Published: 2017

Journal Articles

The Hypofibrinolytic Defect of Nephrotic Syndrome Is Directly Proportional to Disease Severity

Amanda P. Waller, PhD, Katelyn J Wolfgang, Alisa S Wolberg, PhD, Bryce A. Kerlin, MD

Blood (2017) 130 (Supplement 1): 1072.

https://doi.org/10.1182/blood.V130.Suppl_1.1072.1072

Published: 2017

Journal Articles

Prophylactic Effects of Recombinant Thrombomodulin Against Sclerodermatous Chronic Graft-Versus-Host Disease in a Rodent Model

Toshihiro Fujiki, MD, Rie Kuroda, MD, Hideaki Maeba, MD, Kazuhiro Noguchi, MD, Masaki Fukuda, MD, Shintaro Mase, MD, Raita Araki, MD, Yasuhiro Ikawa, MD PhD, Akihiro Yachie, MD PhD, Masayuki Nagasawa, MD PhD, Ryosei Nishimura, MD PhD

Blood (2017) 130 (Supplement 1): 1895.

https://doi.org/10.1182/blood.V130.Suppl_1.1895.1895

Published: 2017

Journal Articles

The Tmprss6 -/- Mouse Model of Iron Refractory Iron Deficiency Anemia (IRIDA) Exhibits Disrupted Phosphate Homeostasis, Elevated Circulating FGF23 Levels, and Increased Fgf23 Expression in Bone Marrow

Xiuqi Li, BS, Larisa Lozovatsky, MS, Abitha Sukumaran, PhD, Steven Tommasini, PhD, Jackie A. Fretz, PhD, Karin E. Finberg, MD PhD

Blood (2017) 130 (Supplement 1): 228.

https://doi.org/10.1182/blood.V130.Suppl_1.228.228

Published: 2017

NARROW

A fully human anti-BMP6 antibody reduces the need for erythropoietin in rodent models of the anemia of chronic disease

Role of MMP-13 in Graft-Versus-Host Disease

Next-Generation FVIII Mimetic Shows Superior Effect in a FIX- and Fx-Humanized Mouse Model In Vivo

Exploitation of a Newly Characterized Metabolic-Cytoskeletal Axis for Effective Combination Therapy of Iron Restricted Anemia

A Phase 1 a/b Dose Escalation Trial to Evaluate the Safety and Tolerability of CG-806 in Patients with Relapsed or Refractory CLL/SLL or Non-Hodgkin's Lymphomas

Preclinical Development of a Bcma Targeting Antibody-Drug Conjugate with Novel Payload for Multiple Myeloma Therapy

SE-7552, a Highly Selective, Non-Hydroxamate Inhibitor of Histone Deacetylase-6 Blocks Multiple Myeloma Growth In Vivo

Novel Insights Into Systemic Iron Regulation

Hepcidin Suppression By Momelotinib Is Associated with Increased Iron Availability and Erythropoiesis in Transfusion-Dependent Myelofibrosis Patients

Prospective, Multi-Center, Phase I Clinical Trial of PLX-R18 Placental Expanded Adherent Stromal Cells in Subjects with Incomplete Hematopoietic Recovery after Hematopoietic Cell Transplantation

SLN124, a Galnac-siRNA Conjugate Targeting TMPRSS6, for the Treatment of Iron Overload and Ineffective Erythropoiesis Such As in Beta-Thalassemia

The Hypofibrinolytic Defect of Nephrotic Syndrome Is Directly Proportional to Fibrin Network Density

Genetic Evidence for Involvement of Human Endogenous Retrovirus Herv-Fc1 in the Pathogenesis of MPNs

A Fully Human Anti-BMP6 Antibody Reduces the Need for Erythropoietin Stimulating Agent in Two Rodent Anemia of Chronic Disease Models

Absence of Plasma Gastric Biomarker Elevations with Chronic Dosing of Avatrombopag, a Novel Oral Thrombopoietin Receptor Agonist, in Patients with Chronic Immune Thrombocytopenia in Phase 3 Trials

A Transient Induction of Blood-Circulating Bile Acid Is a Therapeutic Marker and Target of Chemotherapy-Oriented Myelosuppression

Vitamin D Relation to Busulphan in Pediatrics Undergoing Hematopoietic Stem Cell Transplantation

The Hypofibrinolytic Defect of Nephrotic Syndrome Is Directly Proportional to Disease Severity

Prophylactic Effects of Recombinant Thrombomodulin Against Sclerodermatous Chronic Graft-Versus-Host Disease in a Rodent Model

The Tmprss6 -/- Mouse Model of Iron Refractory Iron Deficiency Anemia (IRIDA) Exhibits Disrupted Phosphate Homeostasis, Elevated Circulating FGF23 Levels, and Increased Fgf23 Expression in Bone Marrow

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