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Journal Articles

Factor VIIa induces extracellular vesicles from the endothelium: a potential mechanism for its hemostatic effect

Kaushik Das, Shiva Keshava, Shabbir A. Ansari, Vijay Kondreddy, Charles T. Esmon, John H. Griffin, Usha R. Pendurthi, L. Vijaya Mohan Rao

Blood (2021) 137 (24): 3428–3442.

https://doi.org/10.1182/blood.2020008417

Published: 2021

Includes: Supplemental data

Journal Articles

Thrombin activation of PAR-1 contributes to microvascular stasis in mouse models of sickle cell disease

Erica M. Sparkenbaugh, Chunsheng Chen, Tomasz Brzoska, Julia Nguyen, Shaobin Wang, Gregory M. Vercellotti, Nigel S. Key, Prithu Sundd, John D. Belcher, Rafal Pawlinski

Blood (2020) 135 (20): 1783–1787.

https://doi.org/10.1182/blood.2019003543

Published: 2020

Includes: Multimedia, Supplemental data

Journal Articles

Factor VIIa Induces Biased Cytoprotective Signaling through the Cleavage of Protease Activated Receptor 1 at Canonical Arg41 Site

Vijay Kumar Reddy Kondreddy, MSc,PhD, Usha R. Pendurthi, PhD, Xiao Xu, John H. Griffin, PhD, L. Vijaya Mohan Rao, PhD

Blood (2019) 134 (Supplement_1): 481.

https://doi.org/10.1182/blood-2019-124976

Published: 2019

Journal Articles

GRK6 Regulates the Hemostatic Response to Injury through Its Rate-Limiting Effects on GPCR Signaling in Platelets

Xi Chen, PhD, Shuchi Gupta, Matthew Cooper, Daniel Dehelian, Xuefei Zhao, Lawrence F. Brass, MD PhD, Ulhas P. Naik, PhD, Meghna Ulhas Naik, MS, Jeffrey Benovic, Peisong Ma, PhD

Blood (2019) 134 (Supplement_1): 3611.

https://doi.org/10.1182/blood-2019-129175

Published: 2019

Journal Articles

Modulation of Thrombin-Induced Platelet Activation By Defibrotide

Kristin N. Maher, MD PhD, Xu Han, BS, MS, Keith B. Neeves, PhD, Marvin T. Nieman, PhD, Jorge Di Paola, MD

Blood (2019) 134 (Supplement_1): 3614.

https://doi.org/10.1182/blood-2019-125945

Published: 2019

Journal Articles

Frequency and Prognostic Impact of IKZF1 and Co-Existed Gene Alterations in Childhood B-ALL in Taiwan

Hsi-Che Liu, MD, Ying-Jung Huang, PhD, Ting-Chi Yeh, MD, Tang-Her Jaing, MD, Chao-Ping Yang, MD, Shih-Hsiang Chen, MD, Jen-Yin Hou, MD, Tung-Huei Lin, MS, Iou-Jih Hung, MD, Lee-Yung Shih, MD

Blood (2019) 134 (Supplement_1): 2750.

https://doi.org/10.1182/blood-2019-128863

Published: 2019

Journal Articles

Prognostic Impact of Chromosomal Abnormalities and Copy Number Alterations Among Adults with B-Cell Precursor Acute Lymphoblastic Leukaemia Treated on UKALL14

Anthony V. Moorman, Ellie Butler, Emilio Barretta, Amy A. Kirkwood, MSc, Claire Schwab, PhD, Thomas Creasey, MBBS, Daniel A. Leongamornlert, PhD, Elli Papaemmanuil, PhD, Pip Patrick, PhDMSc,MA, Laura Clifton-Hadley, PhDBSc, Bela Wrench, MBBS, MD MRCP, FRCPath, Tobias F Menne, MD PhD FRCPath, Andrew K McMillan, FRCP, Christine J. Harrison, PhD FRCPath, Clare J Rowntree, MBBS, PhD FRCP, FRCPath, David I Marks, MBBS, PhD FRCPath, Adele K. Fielding, MBBS,PhDFRCP,FRCPath

Blood (2019) 134 (Supplement_1): 288.

https://doi.org/10.1182/blood-2019-123642

Published: 2019

Journal Articles

Quiescence/Mobilization of Hematopoietic Immature Cells Induced By Polyphenols through Modulation of APC/EPCR/PAR-1 Axis

Cristiane Okuda Torello, PhD, Erich V De Paula, MD PhD, Rodrigo Naoto Shiraishi, PhDstudent, Santos Irene, PhD, Fernanda I Della Via, MSc, Mariana Pissarra, training/fellow, Marisa Claudia Alvarez De Prax, PhD, Mary L. S. Queiroz, MD PhD, Sara T Olalla Saad, PhD

Blood (2019) 134 (Supplement_1): 4996.

https://doi.org/10.1182/blood-2019-127354

Published: 2019

Journal Articles

Unveiling a Critical Role of Thrombin in Enhanced CD8+ T Cell Response to Cancer

Rachel Cantrell, BS, Leah A. Rosenfeldt, BS, Duaa Mureb, BS, Balkrishan Sharma, PhD, Alexey Revenko, PhD, Brett P Monia, PhD, Joseph S. Palumbo, MD

Blood (2019) 134 (Supplement_1): 4918.

https://doi.org/10.1182/blood-2019-128739

Published: 2019

Journal Articles

Thrombin: A Driver or Attenuator of Bone Disease on Hemophilia?

Galen Goldscheitter, BS, BA, Robert Klein, MD, Jason A Taylor, MD PhD

Blood (2019) 134 (Supplement_1): 4916.

https://doi.org/10.1182/blood-2019-130698

Published: 2019

Journal Articles

Links Between Complement Activation and Thrombosis

Wolfram Ruf, MD

Blood (2019) 134 (Supplement_1): SCI-40.

https://doi.org/10.1182/blood-2019-121113

Published: 2019

Journal Articles

Genetic and Genomic Characterisation of Older Adults with Acute Lymphoblastic Leukemia Treated on the UKALL14 and UKALL60+ Clinical Trials

Thomas Creasey, MBBS, Emilio Barretta, Amy A. Kirkwood, MSc, Claire Schwab, PhD, Pip Patrick, PhDMSc,MA, Laura Clifton-Hadley, PhDBSc, Bela Wrench, MBBS, MD MRCP, FRCPath, Tobias F Menne, MD PhD FRCPath, Andrew K McMillan, FRCP, Nicholas J. Morley, John A Snowden, BSc (Hons), MBChB, MD FRCP, FRCPath, Christine J. Harrison, PhD FRCPath, Daniel A. Leongamornlert, PhD, Elli Papaemmanuil, PhD, Clare J Rowntree, MBBS, PhD FRCP, FRCPath, David I Marks, MBBS, PhD FRCPath, Adele K. Fielding, MBBS,PhDFRCP,FRCPath, Anthony V. Moorman

Blood (2019) 134 (Supplement_1): 2746.

https://doi.org/10.1182/blood-2019-124395

Published: 2019

Journal Articles

Blockade of Lipid Receptor GPR31 Suppresses Platelet Reactivity and Thrombosis with Minimal Effect on Hemostasis

Layla Van Doren, MD, Nga Nguyen, BSc, Chris Garzia, BSc, Elizabeth Fletcher, PhD, Ryan Stevenson, MD, David Jaramillo, MSc, Athan Kuliopulos, MD PhD, Lidija Covic, PhD

Blood (2019) 134 (Supplement_1): 1064.

https://doi.org/10.1182/blood-2019-126111

Published: 2019

Journal Articles

Activated protein C ameliorates chronic graft-versus-host disease by PAR1-dependent biased cell signaling on T cells

Ranjeet K. Sinha, Ryan Flynn, Michael Zaiken, Katelyn Paz, Amanda L. Gavin, David Nemazee, José A. Fernández, Xiao Xu, John H. Griffin, Bruce R. Blazar

Blood (2019) 134 (9): 776–781.

https://doi.org/10.1182/blood.2019001259

Published: 2019

Journal Articles

Polyphenols Modulate Quiescence/Mobilization of Hematopoietic Immature Cells through APC/EPCR/PAR-1 Axis

Cristiane O Torello, PhD, Erich Vinicius De Paula, MD PhD, Rodrigo Naoto Shiraishi, training/fellow, Tamara C. Lopes de Castro, undergraduate, Fernanda Martins, PhD, Fernanda I Della Via, PhDstudent, Marisa Claudia Alvarez De Prax, PhD, Mary L. S. Queiroz, MD PhD, Sara T. Olalla Saad, MD PhD

Blood (2018) 132 (Supplement 1): 3830.

https://doi.org/10.1182/blood-2018-99-114902

Published: 2018

Journal Articles

Genomics Reveal Potential Biomarkers of Response to Pembrolizumab after High Dose Cytarabine in an Ongoing Phase II Trial in Relapsed/Refractory AML

Blood (2018) 132 (Supplement 1): 4054.

https://doi.org/10.1182/blood-2018-99-116608

Published: 2018

Journal Articles

Thrombin-Mediated Activation of PAR-1 Contributes to Microvascular Stasis in Mouse Models of Sickle Cell Disease Via Increased Endothelial Expression of P-Selectin and VWF

Erica Sparkenbaugh, PhD BS, Chunsheng Chen, MD, Julia Nguyen, BS, Shaobin Wang, PhD, Gregory M. Vercellotti, MD, John D Belcher, PhD, Rafal Pawlinski, PhD

Blood (2018) 132 (Supplement 1): 266.

https://doi.org/10.1182/blood-2018-99-116238

Published: 2018

Journal Articles

Platelet Dysfunction and Cellular Microparticles May be Involved in the Hipercoagulable State Observed in Obstructive Sleep Apnea Syndrome

Ihosvany Fernandez-Bello, Raul Justo Sanz, Elena Monzón Manzano, Francisco García Río, PhD, Carolina Cubillos, PhD, Cristina Balbás-García, Teresa Álvarez-Roman, Mónica Martín, María Isabel Rivas Pollmar, Miguel A. Canales, Victor Jimenez-Yuste, Nora Butta, PhD

Blood (2018) 132 (Supplement 1): 5048.

https://doi.org/10.1182/blood-2018-99-116018

Published: 2018

Journal Articles

Inflammation and Tissue Damage Mediated By PAR-1 Expression Is Cell Type-Specific and Varies Depending on the Inflammatory Challenge

Alexander A Boucher, MD, Leah A. Rosenfeldt, BS, Duaa Mureb, BS, Anna K Kopec, PhD, James P. Luyendyk, PhD, Matthew J. Flick, PhD, Joseph S. Palumbo, MD

Blood (2018) 132 (Supplement 1): 133.

https://doi.org/10.1182/blood-2018-99-117312

Published: 2018

Journal Articles

Integrin Alphav-beta3 on Podocytes Orchestrates Coagulation Protease Signaling through Protease-Activated Receptors

Madhusudhan Thati, PhD, Sanchita Ghosh, MS, Hongjie Wang, MD PhD, Wolfram Ruf, MD, Berend H. Isermann, MD

Blood (2018) 132 (Supplement 1): 137.

https://doi.org/10.1182/blood-2018-99-114566

Published: 2018

NARROW

Factor VIIa induces extracellular vesicles from the endothelium: a potential mechanism for its hemostatic effect

Thrombin activation of PAR-1 contributes to microvascular stasis in mouse models of sickle cell disease

Factor VIIa Induces Biased Cytoprotective Signaling through the Cleavage of Protease Activated Receptor 1 at Canonical Arg41 Site

GRK6 Regulates the Hemostatic Response to Injury through Its Rate-Limiting Effects on GPCR Signaling in Platelets

Modulation of Thrombin-Induced Platelet Activation By Defibrotide

Frequency and Prognostic Impact of IKZF1 and Co-Existed Gene Alterations in Childhood B-ALL in Taiwan

Prognostic Impact of Chromosomal Abnormalities and Copy Number Alterations Among Adults with B-Cell Precursor Acute Lymphoblastic Leukaemia Treated on UKALL14

Quiescence/Mobilization of Hematopoietic Immature Cells Induced By Polyphenols through Modulation of APC/EPCR/PAR-1 Axis

Unveiling a Critical Role of Thrombin in Enhanced CD8+ T Cell Response to Cancer

Thrombin: A Driver or Attenuator of Bone Disease on Hemophilia?

Links Between Complement Activation and Thrombosis

Genetic and Genomic Characterisation of Older Adults with Acute Lymphoblastic Leukemia Treated on the UKALL14 and UKALL60+ Clinical Trials

Blockade of Lipid Receptor GPR31 Suppresses Platelet Reactivity and Thrombosis with Minimal Effect on Hemostasis

Activated protein C ameliorates chronic graft-versus-host disease by PAR1-dependent biased cell signaling on T cells

Polyphenols Modulate Quiescence/Mobilization of Hematopoietic Immature Cells through APC/EPCR/PAR-1 Axis

Genomics Reveal Potential Biomarkers of Response to Pembrolizumab after High Dose Cytarabine in an Ongoing Phase II Trial in Relapsed/Refractory AML

Thrombin-Mediated Activation of PAR-1 Contributes to Microvascular Stasis in Mouse Models of Sickle Cell Disease Via Increased Endothelial Expression of P-Selectin and VWF

Platelet Dysfunction and Cellular Microparticles May be Involved in the Hipercoagulable State Observed in Obstructive Sleep Apnea Syndrome

Inflammation and Tissue Damage Mediated By PAR-1 Expression Is Cell Type-Specific and Varies Depending on the Inflammatory Challenge

Integrin Alphav-beta3 on Podocytes Orchestrates Coagulation Protease Signaling through Protease-Activated Receptors

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American Society of Hematology

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American Society of Hematology

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