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Journal Articles

Factor XIII cross-links fibrin(ogen) independent of fibrin polymerization in experimental acute liver injury

Lauren G. Poole, Anna K. Kopec, Dafna J. Groeneveld, Asmita Pant, Kevin S. Baker, Holly M. Cline-Fedewa, Matthew J. Flick, James P. Luyendyk

Blood (2021) 137 (18): 2520–2531.

https://doi.org/10.1182/blood.2020007415

Published: 2021

Includes: Supplemental data

Journal Articles

MKL1 deficiency results in a severe neutrophil motility defect due to impaired actin polymerization

Blood (2020) 135 (24): 2171–2181.

https://doi.org/10.1182/blood.2019002633

Published: 2020

Includes: Multimedia, Supplemental data

Journal Articles

Hemoglobin S Polymerization Can be Inhibited By Alterations in Erythrocyte Glycolysis

William R. Simmons, Quan Li, PhD, John A. Hausman, Suilan Zheng, PhD, William Eaton, MD, Philip S. Low, PhD, David M. Bodine, PhD

Blood (2019) 134 (Supplement_1): 977.

https://doi.org/10.1182/blood-2019-121709

Published: 2019

Journal Articles

Anticancer Activity of a Highly Potent Small Molecule Tubulin Polymerization Inhibitor, AB8939

Martine Humbert, PhD, Armelle Goubard, PhD, Colin Mansfield, PhD, Olivier Hermine, MD PhD, Patrice Dubreuil, PhD, The AB8939 Study Group

Blood (2019) 134 (Supplement_1): 2075.

https://doi.org/10.1182/blood-2019-122540

Published: 2019

Journal Articles

LIC-R2 Values Predict Severity of SCD: Baseline Data from Licnet-S

Rosario Di Maggio, MD, Angela Vitrano, PhD, Carmelo Fidone, MD, Alessandra Quota, MD, Daniela Fiorino, MD, Calogera Gerardi, MD, Saveria Campisi, MD, Lorenzo Tesé, MD, Vincenzo Santoro, MD, Barone Rita, MD, Giangreco Antonino, MD, Paolo Rigano, Lorella Pitrolo, MD, Aurelio Maggio, MD

Blood (2019) 134 (Supplement_1): 4810.

https://doi.org/10.1182/blood-2019-124728

Published: 2019

Journal Articles

MetAP2 Inhibition Modifies Hemoglobin S (HbS) to Delay Polymerization and Improve Blood Flow in Sickle Cell Disease

Melanie Demers, PhD, Sarah Sturtevant, BSc, Kevin Guertin, PhD, Dipti Gupta, Kunal Desai, MS, Benjamin Vieira, BS, Alexandra Hicks, PhD, Ayman Ismail, PhD, Yukio Nakamura, MD PhD, Bronner Goncalves, MD PhD, Giuseppe Di Caprio, PhD, Ethan Schonbrun, PhD, Scott Hansen, BS, Martin K. Safo, PhD, David K. Wood, PhD, John M. Higgins, MD PhD, David R. Light, PhD

Blood (2019) 134 (Supplement_1): 2260.

https://doi.org/10.1182/blood-2019-128727

Published: 2019

Journal Articles

Investigation of Cell-Contact Dependent Alterations in Immune Synapse Formation between T Cells and BCP-ALL Cells

Britta Wenske, PhD, Lothar Marischen, PhD, Julia Welzenbach, André Heimbach, PhD, Per Hoffmann, PhD, Selim Corbacioglu, MD, David A Williams, MD, Anja Troeger, MD

Blood (2019) 134 (Supplement_1): 2754.

https://doi.org/10.1182/blood-2019-128835

Published: 2019

Journal Articles

Formin Links Erythroid Cytoskeleton to Organelle Clearance through Escrt-III Complex during Reticulocyte Maturation

Yijie Liu, PhD, Haiyan Bao, MD, Yang Mei, PhD, Xu Han, PhD, Peng Ji, MD PhD

Blood (2019) 134 (Supplement_1): 151.

https://doi.org/10.1182/blood-2019-125157

Published: 2019

Journal Articles

Harnessing a Novel Dyrk1a-Ablim2-MKL1 Regulatory Module in Megakaryocyte Morphogenesis to Enable Scalable Platelet "Pharming"

Kamaleldin E Elagib, PhDMBBS, Ashton Brock, PhD, Goar Mosoyan, Cara Clementelli, Lorrie L Delehanty, BS, Alexandra Pacheco-Benichou, Corinne Fruit, Thierry Besson, PhD, Stephen Morris, MD, Koji Eto, MD, Camelia Iancu-Rubin, PhD, Adam N Goldfarb, MD

Blood (2019) 134 (Supplement_1): 3250.

https://doi.org/10.1182/blood-2019-129049

Published: 2019

Journal Articles

Primary polymerization prevention

Martin H Steinberg

Blood (2019) 133 (17): 1797–1798.

https://doi.org/10.1182/blood-2019-02-898767

Published: 2019

Journal Articles

Results from Part A of the Hemoglobin Oxygen Affinity Modulation to Inhibit HbS Polymerization (HOPE) Trial (GBT440-031), a Placebo-Controlled Randomized Study Evaluating Voxelotor (GBT440) in Adults and Adolescents with Sickle Cell Disease

Blood (2018) 132 (Supplement 1): 505.

https://doi.org/10.1182/blood-2018-99-118508

Published: 2018

Journal Articles

Elucidation of the IMiDs-Resistant Mechanism and Development of the Overcoming Drugs Inducing CRBN Independent G2/M Cell Cycle Arrest in Myeloma Cells

Ryo Uozaki, Shuji Aida, Takasi Yamagughi, Tomofumi Yamamoto, BPharm, Sho Kashiwazaki, Hiroshi Yanagawa, Daiju Ichikawa, Maiko Matsushita, Yutaka Hattori

Blood (2018) 132 (Supplement 1): 4451.

https://doi.org/10.1182/blood-2018-99-115909

Published: 2018

Journal Articles

Dynamins 2 and 3 Are Required for Human Megakaryocytes Directional Migration

Praveen K Suraneni, PhD, Seth J. Corey, MD, Michael Hession, BS, Rameez Ishaq, Arinola Awomolo, Shirin Hasan, PhD, Najet Debili, PhD, John D. Crispino, PhD MBA, Elizabeth A. Eklund, MD, Yolande Chen, MD

Blood (2018) 132 (Supplement 1): 2429.

https://doi.org/10.1182/blood-2018-99-118782

Published: 2018

Journal Articles

Sickle Cell Education for Medical Professionals: A Pre and Post Test Analysis

Diana D Simmons, FNP-C, Robert Lucia, DNP(c), RN, LCPC, CT, Kay Linn Saving, MD, Nicole Alwan, BS

Blood (2018) 132 (Supplement 1): 5812.

https://doi.org/10.1182/blood-2018-99-111371

Published: 2018

Journal Articles

CK2β regulates thrombopoiesis and Ca 2+ -triggered platelet activation in arterial thrombosis

Blood (2017) 130 (25): 2774–2785.

https://doi.org/10.1182/blood-2017-05-784413

Published: 2017

Includes: Multimedia, Supplemental data

Journal Articles

Initial Results from a Cohort in a Phase 2a Study (GBT440-007) Evaluating Adolescents with Sickle Cell Disease Treated with Multiple Doses of GBT440, a HbS Polymerization Inhibitor

Carolyn C Hoppe, MD, Adlette C. Inati, MD, Clark Brown, MD PhD, Winfred Wang, MD, Victor R. Gordeuk, MD, Robert Liem, MD, Gerald Woods, MD, Connie M. Piccone, MD, Erica Fong, Ganesh Balaratnam, MD, Sandy Dixon, Margaret E Tonda, PharmD, Carla B Washington, PhD, Yifah Yaron, MD PhD, Josh Lehrer, MD MPhil, FACC

Blood (2017) 130 (Supplement 1): 689.

https://doi.org/10.1182/blood.V130.Suppl_1.689.689

Published: 2017

Journal Articles

Coagulopathy in Patients with Plasmacellular Dyscrasia

Francesca Martini, Gabriele Buda, MD PhD, Nadia Cecconi, Dr, Laura Caponi, Aldo Paolicchi, MD, Mario Petrini, PhD MD Prof

Blood (2017) 130 (Supplement 1): 4867.

https://doi.org/10.1182/blood.V130.Suppl_1.4867.4867

Published: 2017

Journal Articles

Wave-Complex-Dependent Actin Dynamics Controls Hematopoietic Stem Cell Bone Marrow Retention and Orderly Differentiation into Mature Hematopoietic Lineages

Eliza Wiercinska, PhD, David de Gorter, PhD, Eva Danner, Sabine Harenkamp, Andre Gorgens, PhD, Anja Schwiebs, PhD, Theresia Stradal, PhD, Halvard Bonig, MD MA

Blood (2017) 130 (Supplement 1): 2417.

https://doi.org/10.1182/blood.V130.Suppl_1.2417.2417

Published: 2017

Journal Articles

Treating sickle cell disease by targeting HbS polymerization

William A. Eaton, H. Franklin Bunn

Blood (2017) 129 (20): 2719–2726.

https://doi.org/10.1182/blood-2017-02-765891

Published: 2017

Journal Articles

The 10-Item Sickle Cell Disease Severity Measure (SCDSM-10): A Novel Measure of Daily SCD Symptom Severity Developed to Assess Benefit of GBT440, an Experimental HbS Polymerization Inhibitor

Laurie Burke, BPharm, MPH, Jeremy Charles Hobart, MD PhD FRCP, MBBS, BSc, Kathleen Fox, PhD, Josh Lehrer-Graiwer, MD MPhil, FACC, Kenneth Bridges, MD, Martine Kraus, PhD, Eleanor Ramos, MD

Blood (2016) 128 (22): 4760.

https://doi.org/10.1182/blood.V128.22.4760.4760

Published: 2016

NARROW

Factor XIII cross-links fibrin(ogen) independent of fibrin polymerization in experimental acute liver injury

MKL1 deficiency results in a severe neutrophil motility defect due to impaired actin polymerization

Hemoglobin S Polymerization Can be Inhibited By Alterations in Erythrocyte Glycolysis

Anticancer Activity of a Highly Potent Small Molecule Tubulin Polymerization Inhibitor, AB8939

LIC-R2 Values Predict Severity of SCD: Baseline Data from Licnet-S

MetAP2 Inhibition Modifies Hemoglobin S (HbS) to Delay Polymerization and Improve Blood Flow in Sickle Cell Disease

Investigation of Cell-Contact Dependent Alterations in Immune Synapse Formation between T Cells and BCP-ALL Cells

Formin Links Erythroid Cytoskeleton to Organelle Clearance through Escrt-III Complex during Reticulocyte Maturation

Harnessing a Novel Dyrk1a-Ablim2-MKL1 Regulatory Module in Megakaryocyte Morphogenesis to Enable Scalable Platelet "Pharming"

Primary polymerization prevention

Results from Part A of the Hemoglobin Oxygen Affinity Modulation to Inhibit HbS Polymerization (HOPE) Trial (GBT440-031), a Placebo-Controlled Randomized Study Evaluating Voxelotor (GBT440) in Adults and Adolescents with Sickle Cell Disease

Elucidation of the IMiDs-Resistant Mechanism and Development of the Overcoming Drugs Inducing CRBN Independent G2/M Cell Cycle Arrest in Myeloma Cells

Dynamins 2 and 3 Are Required for Human Megakaryocytes Directional Migration

Sickle Cell Education for Medical Professionals: A Pre and Post Test Analysis

CK2β regulates thrombopoiesis and Ca 2+ -triggered platelet activation in arterial thrombosis

Initial Results from a Cohort in a Phase 2a Study (GBT440-007) Evaluating Adolescents with Sickle Cell Disease Treated with Multiple Doses of GBT440, a HbS Polymerization Inhibitor

Coagulopathy in Patients with Plasmacellular Dyscrasia

Wave-Complex-Dependent Actin Dynamics Controls Hematopoietic Stem Cell Bone Marrow Retention and Orderly Differentiation into Mature Hematopoietic Lineages

Treating sickle cell disease by targeting HbS polymerization

The 10-Item Sickle Cell Disease Severity Measure (SCDSM-10): A Novel Measure of Daily SCD Symptom Severity Developed to Assess Benefit of GBT440, an Experimental HbS Polymerization Inhibitor

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American Society of Hematology

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ASH Publications

American Society of Hematology

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