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Journal Articles

Constitutively Activated STAT3 Induces the Expression of Gli1 in Chronic Lymphocytic Leukemia Cells

Uri Rozovski, MD, David M. Harris, PhD, Ping Li, PhD, Zhiming Liu, BS, Taghi Manshouri, PhD, Ivo Veletic, MD, Preetesh Jain, MBBS,MDDM,PhD, Alessandra Ferrajoli, MD, Jan A. Burger, MD PhD, Prithviraj Bose, MD, Philip A. Thompson, MBBS, Nitin Jain, MD, Srdan Verstovsek, MD PhD, William G. Wierda, MD PhD, Michael J Keating, MBBS, Zeev E. Estrov, MD

Blood (2019) 134 (Supplement_1): 3018.

https://doi.org/10.1182/blood-2019-124014

Published: 2019

Journal Articles

Constitutively Activated STAT3 Induces the Production of PTX3 That Contributes to the Induction of Bone Marrow Reticulin Fibrosis in Patient with CLL

Blood (2019) 134 (Supplement_1): 3024.

https://doi.org/10.1182/blood-2019-124183

Published: 2019

Journal Articles

CLL Cells with 13q- Are Characterized By High BCL2 Levels and CLL Cells with Trisomy-12 By Increased Activation of STAT3 and NF-κB

Uri Rozovski, David M. Harris, Ping Li, PhD, Zhiming Liu, Preetesh Jain, MBBS, MDDM, PhD, Alessandra Ferrajoli, MD, Jan A. Burger, MD PhD, Prithviraj Bose, MD, Philip A. Thompson, MBBS, Nitin Jain, MD, William G. Wierda, MD PhD, Michael J. Keating, MD, Zeev E. Estrov, MD

Blood (2018) 132 (Supplement 1): 4411.

https://doi.org/10.1182/blood-2018-99-114909

Published: 2018

Journal Articles

A Novel Metabolic Transcriptome Identified in Myelodysplastic Syndromes (MDS) Correlates with OMS Classification and Poor Prognosis

Christophe Desterke, Estelle Balducci, Xavier Fund, Claire Borie, Annelise Bennaceur-Griscelli, MD PhD, Ali G Turhan, MD PhD

Blood (2018) 132 (Supplement 1): 5495.

https://doi.org/10.1182/blood-2018-99-110678

Published: 2018

Journal Articles

Endogenous STAT3-Activated Wnt5a Provides CLL Cells with Survival Advantage

Uri Rozovski, Ping Li, PhD, David M. Harris, Zhiming Liu, Preetesh Jain, MBBS, MDDM, PhD, Alessandra Ferrajoli, MD, Jan A. Burger, MD PhD, Prithviraj Bose, MD, Philip A. Thompson, MBBS, Nitin Jain, MD, William G. Wierda, MD PhD, Michael J. Keating, MD, Zeev E. Estrov, MD

Blood (2018) 132 (Supplement 1): 4398.

https://doi.org/10.1182/blood-2018-99-111960

Published: 2018

Journal Articles

Th17 Cells Targeting By MiR-21 Inhibitor Impairs Multiple Myeloma Related Bone Disease

Marco Rossi, Emanuela Altomare, Nicola Amodio, PhD, Maria Teresa Di Martino, Marco Gaspari, Domenico Taverna, Domenica Scumaci, Francesco Conforti, Daniele Caracciolo, Cirino Botta, Cinzia Federico, Annamaria Gullà, Eugenio Morelli, Francesca Scionti, Mariamena Arbitrio, MD, Paola Critelli, Antonino Neri, Pierosandro Tagliaferri, Pierfrancesco Tassone, MD

Blood (2017) 130 (Supplement 1): 4380.

https://doi.org/10.1182/blood.V130.Suppl_1.4380.4380

Published: 2017

Journal Articles

Casein Kinase-2 Induces Constitutive Phosphorylation of STAT3 in CLL Cells

Uri Rozovski, MD, David M. Harris, Ping LI, PhD, Zhiming Liu, Preetesh Jain, MBBS, MDDM, PhD, Alessandra Ferrajoli, MD, Jan A. Burger, MD PhD, Susan M. O'Brien, MD, Prithviraj Bose, MD, Philip A. Thompson, MBBS, Nitin Jain, MD, William G. Wierda, MD PhD, Michael Keating, MBBS, Zeev Estrov, MD

Blood (2016) 128 (22): 4374.

https://doi.org/10.1182/blood.V128.22.4374.4374

Published: 2016

Journal Articles

Lyn sustains oncogenic signaling in chronic lymphocytic leukemia by strengthening SET-mediated inhibition of PP2A

Francesca Zonta, Mario Angelo Pagano, Livio Trentin, Elena Tibaldi, Federica Frezzato, Valentina Trimarco, Monica Facco, Giuseppe Zagotto, Valeria Pavan, Giovanni Ribaudo, Luciana Bordin, Gianpietro Semenzato, Anna Maria Brunati

Blood (2015) 125 (24): 3747–3755.

https://doi.org/10.1182/blood-2014-12-619155

Published: 2015

Includes: Supplemental data

Journal Articles

The Prognostic Significance Of DUSP3 In DLBCL

Rachel R. Fang, Ph.D., Yulian Xu, Chen-feng Qi, M.D., Herbert Morse, III, MD, Jeff Xiwu Zhou, M.D., Ph.D.

Blood (2013) 122 (21): 3025.

https://doi.org/10.1182/blood.V122.21.3025.3025

Published: 2013

Journal Articles

Serine 559 Of Glycoprotein Ibα Is Phosphorylated By Protein Kinase A Which Plays Key Roles In Regulating Von Willebrand Factor Binding, Surface Expression, and Signaling Of Glycoprotein Ib-IX

Jie Zhang, PhD, Weilin Zhang, PhD, Guanglei Liu, Lili Zhao, Rong Yan, PhD, Kesheng Dai, PhD

Blood (2013) 122 (21): 3520.

https://doi.org/10.1182/blood.V122.21.3520.3520

Published: 2013

Journal Articles

Signal Transducer and Activator Of Transcription 3 Activates and Deregulates Micro RNA Expression In Chronic Lymphocytic Leukemia Cells

Rozovski Uri, MD, George Calin, MD PhD, Tetsoro Setoyama, Abundu Lucilla, Harris David, Ping Li, PhD, Lui Zhiming, Grugurevic Srdana, Alessandra Ferrajoli, MD, Stefan H. Faderl, MD, Jan A. Burger, MD, PhD, Susan O'Brien, MD, William G. Wierda, MD, PhD, Michael J. Keating, MD, Zeev Estrov, MD

Blood (2013) 122 (21): 4152.

https://doi.org/10.1182/blood.V122.21.4152.4152

Published: 2013

Journal Articles

Normal ABL1 Is a Tumor Suppressor and Therapeutic Target In BCR-ABL1–positive Leukemias

Yashodhara Dasgupta, Mateusz Koptyra, PhD, Margaret Nieborowska-Skorska, MD, PhD, Elisabeth Bolton Gillespie, PhD, Tomasz Stoklosa, MD, PhD, Grazyna Hoser, PhD, Mariusz Wasik, MD, Markus Muschen, Christine Richardson, PhD, Tomasz Skorski, MD, PhD

Blood (2013) 122 (21): 1466.

https://doi.org/10.1182/blood.V122.21.1466.1466

Published: 2013

Journal Articles

STAT3 Activates Anti-Apoptotic Genes But When In Access Induces Apoptosis Of CLL Cells

Rozovski Uri, MD, David Harris, Ping Li, PhD, Zhiming Liu, Ji Yuan, Srdana Grugurevic, Susan Lerner, MS, William G. Wierda, MD, Michael J. Keating, MD, Zeev Estrov, MD

Blood (2013) 122 (21): 5294.

https://doi.org/10.1182/blood.V122.21.5294.5294

Published: 2013

Journal Articles

Reversible Association of 14-3-3 with Platelet Glycoprotein Ibα Regulates the Ability of Cells to Adhere, Roll and Spread On VWF

Adam D. Munday, PhD, Jose A. Lopez, MD

Blood (2012) 120 (21): 1061.

https://doi.org/10.1182/blood.V120.21.1061.1061

Published: 2012

Journal Articles

Signal Transducer and Activator of Transcription (STAT)-3 Induces Granulocyte/Macrophage Colony-Stimulating Factor (GM-CSF) Receptor-α Expression in Chronic Lymphocytic Leukemia (CLL) Cells,

Ping Li, PhD, Zhiming Liu, MS, David Harris, BS, Alessandra Ferrajoli, MD, Yongtao Wang, MD, Inbal Hazan-Halevy, PhD, Srdana Grgurevic, MS, William G. Wierda, MD, PhD, Jan A. Burger, MD, PhD, Susan O'Brien, MD, Stefan Faderl, MD, Michael J Keating, MD, Zeev Estrov

Blood (2011) 118 (21): 3879.

https://doi.org/10.1182/blood.V118.21.3879.3879

Published: 2011

Journal Articles

A Phase I/II Study of Vorinostat (SAHA), Cladribine (2-CdA), and Rituximab Shows Significant Activity in Previously Untreated Mantle Cell Lymphoma

Stephen Spurgeon, MD, Andy I Chen, MD, PhD, Craig Okada, MD, PhD, Samir Parekh, MD, Violetta V. Leshchenko, PhD, Gundula Palmbach, Bashi Ratterree, RN, Nan Subbiah, Christine Capper, RN, Elliot M Epner, MD, PhD

Blood (2011) 118 (21): 441.

https://doi.org/10.1182/blood.V118.21.441.441

Published: 2011

Journal Articles

Role of BCR in Down-Modulation of BCR-ABL Oncogenicity in CML

Bastianella Perazzona, Ph.D., Yan Wang, M.D., Ralph B. Arlinghaus, PhD

Blood (2008) 112 (11): 3210.

https://doi.org/10.1182/blood.V112.11.3210.3210

Published: 2008

Journal Articles

Lipid and Protein Substrates of PI3K in Cytokine Receptor Survival Signalling: Deregulation in Leukemia

Daniel Thomas, MD, Joanna Woodcock, PhD, Jason A Powell, PhD, Emma F Barry, Angel F Lopez, Mark A Guthridge, PhD

Blood (2008) 112 (11): 3864.

https://doi.org/10.1182/blood.V112.11.3864.3864

Published: 2008

Journal Articles

Inhibition of the Binding of von Willebrand Factor to the Platelet Glycoprotein Ib-IX with an Inhibitor of 14-3-3 and Glycoprotein Ib-IX Interaction.

Kesheng Dai, PhD, Richard Bodnar, PhD, Michael Berndt, PhD, Xiaoping Du, PhD

Blood (2005) 106 (11): 1657.

https://doi.org/10.1182/blood.V106.11.1657.1657

Published: 2005

Journal Articles

Differential Phosphorylation of FANCA and FANCG Determines Response of Fanconi Anemia Core Complex to DNA Damage and S Phase.

Jun Mi, Ph.D., Andrei Tomashevski, Ph.D., Gary M. Kupfer, M.D.

Blood (2004) 104 (11): 726.

https://doi.org/10.1182/blood.V104.11.726.726

Published: 2004

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Constitutively Activated STAT3 Induces the Expression of Gli1 in Chronic Lymphocytic Leukemia Cells

Constitutively Activated STAT3 Induces the Production of PTX3 That Contributes to the Induction of Bone Marrow Reticulin Fibrosis in Patient with CLL

CLL Cells with 13q- Are Characterized By High BCL2 Levels and CLL Cells with Trisomy-12 By Increased Activation of STAT3 and NF-κB

A Novel Metabolic Transcriptome Identified in Myelodysplastic Syndromes (MDS) Correlates with OMS Classification and Poor Prognosis

Endogenous STAT3-Activated Wnt5a Provides CLL Cells with Survival Advantage

Th17 Cells Targeting By MiR-21 Inhibitor Impairs Multiple Myeloma Related Bone Disease

Casein Kinase-2 Induces Constitutive Phosphorylation of STAT3 in CLL Cells

Lyn sustains oncogenic signaling in chronic lymphocytic leukemia by strengthening SET-mediated inhibition of PP2A

The Prognostic Significance Of DUSP3 In DLBCL

Serine 559 Of Glycoprotein Ibα Is Phosphorylated By Protein Kinase A Which Plays Key Roles In Regulating Von Willebrand Factor Binding, Surface Expression, and Signaling Of Glycoprotein Ib-IX

Signal Transducer and Activator Of Transcription 3 Activates and Deregulates Micro RNA Expression In Chronic Lymphocytic Leukemia Cells

Normal ABL1 Is a Tumor Suppressor and Therapeutic Target In BCR-ABL1–positive Leukemias

STAT3 Activates Anti-Apoptotic Genes But When In Access Induces Apoptosis Of CLL Cells

Reversible Association of 14-3-3 with Platelet Glycoprotein Ibα Regulates the Ability of Cells to Adhere, Roll and Spread On VWF

Signal Transducer and Activator of Transcription (STAT)-3 Induces Granulocyte/Macrophage Colony-Stimulating Factor (GM-CSF) Receptor-α Expression in Chronic Lymphocytic Leukemia (CLL) Cells,

A Phase I/II Study of Vorinostat (SAHA), Cladribine (2-CdA), and Rituximab Shows Significant Activity in Previously Untreated Mantle Cell Lymphoma

Role of BCR in Down-Modulation of BCR-ABL Oncogenicity in CML

Lipid and Protein Substrates of PI3K in Cytokine Receptor Survival Signalling: Deregulation in Leukemia

Inhibition of the Binding of von Willebrand Factor to the Platelet Glycoprotein Ib-IX with an Inhibitor of 14-3-3 and Glycoprotein Ib-IX Interaction.

Differential Phosphorylation of FANCA and FANCG Determines Response of Fanconi Anemia Core Complex to DNA Damage and S Phase.

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