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Journal Articles

Integrated Genomic, Functional and Prognostic Characterization of Atypical Chronic Myeloid Leukemia (aCML) in a Cohort of 43 Patients

Diletta Fontana, PhD, Daniele Ramazzotti, PhD, Andrea Aroldi, MD, Antonio Niro, MS, Luca Massimino, PhD, Delphine Rea, MD, Fabio Stagno, MD, Bruno Martino, MD, Leonardo Campiotti, MD, Giovanni Caocci, MD, Elena Maria Elli, MD, Monica Fumagalli, MD, Fabio Ciceri, MD, Rocco Piazza, MD PhD, Carlo Gambacorti-Passerini, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 1714.
https://doi.org/10.1182/blood-2019-126467
Published: 2019
Journal Articles

Menin Is a Therapeutic Target in MN1 High Leukemia

Clara Libbrecht, MD, Simone Stefanie Riedel, PhD, Jessica Haladyna, BA,MS, Kathrin M. Bernt, MD
Journal: Blood
Blood (2018) 132 (Supplement 1): 758.
https://doi.org/10.1182/blood-2018-99-115551
Published: 2018
Journal Articles

MLL-Menin Inhibition Reverses Pre-Leukemic Progenitor Self-Renewal Induced By NPM1 Mutations and Prevents AML Development

Hannah J. Uckelmann, PhD, Stephanie M. Kim, BA, Noa J. C. Antonissen, Andrei V. Krivtsov, PhD, Charles Hatton, Gerard M. McGeehan, PhD, Ross L. Levine, MD, George S. Vassiliou, Scott A. Armstrong, MD PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 546.
https://doi.org/10.1182/blood-2018-99-110851
Published: 2018
Journal Articles

Mechanisms of Venetoclax Resistance in Chronic Lymphocytic Leukemia

Lukas P. Frenzel, MD, Carmen D. Herling, MD PhD, Nima Abedpour, PhD, Jonathan Weiss, PhD, Petra Mayer, Maria Cartolano, PhD, Valeska Berg, PhD, Nadine Kutsch, MD, Paula Cramer, MD, Clemens-Martin Wendtner, MD, Thorsten Persigehl, MD, Andreas Saleh, MD, Janine Altmüller, PhD, Peter Nürnberg, PhD, Christian Pallasch, MD, Viktor Achter, PhD, Ulrich Lang, PhD, Barbara F. Eichhorst, MD, Roberta Castiglione, MD, Stephan C. Schaefer, MD, Reinhard Buettner, MD, Karl-Anton Kreuzer, MD, Hans Christian Reinhardt, MD, Michael J. Hallek, MD, Martin Peifer, PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 263.
https://doi.org/10.1182/blood.V130.Suppl_1.263.263
Published: 2017
Journal Articles

A Crispr/Cas9 Drop-out Screen Identifies Genome-Wide Genetic Valnerubilities in Acute Myeloid Leukaemia

Konstantinos Tzelepis, MSc, Hiroko Koike-Yusa, MD, Etienne De Braekeleer, PhD, Yilong Li, Emmanouil Metzakopian, PhD, Oliver M. Dovey, PhD, Annalisa Mupo, PhD, Vera Grinkevich, PhD, Milena M. Mazan, PhD, Malgorzata Gozdecka, PhD, Jonathan L. Cooper, Miten Patel, MD, Thomas David Hardman McKerrell, MD, Bin Chen, Hannes Ponstingl, PhD, Brian J.P Huntly, MD PhD, Ultan McDermott, MD PhD, Julio Saez-Rodriguez, PhD, Francesco Iorio, PhD, Kosuke Yusa, PhD, George S. Vassiliou, MD PhD
Journal: Blood
Blood (2015) 126 (23): 554.
https://doi.org/10.1182/blood.V126.23.554.554
Published: 2015
Journal Articles

Pre-Diagnosis Plasma Immune Markers and Risk of Non-Hodgkin Lymphoma and Its Major Histologic Subtypes: A Prospective Analysis in Two Large Cohorts

Brenda M. Birmann, ScD, Mara M. Epstein, ScD, Elizabeth C. Breen, PhD, Kimberly A. Bertrand, ScD, Francine Laden, ScD, Bernard A. Rosner, PhD, Edward Giovannucci, MD ScD, Larry I. Magpantay, BSc, Otoniel Martinez-Maza, PhD
Journal: Blood
Blood (2014) 124 (21): 3029.
https://doi.org/10.1182/blood.V124.21.3029.3029
Published: 2014
Journal Articles

Distinct pathways regulated by menin and by MLL1 in hematopoietic stem cells and developing B cells

Bin E. Li, Tao Gan, Matthew Meyerson, Terence H. Rabbitts, Patricia Ernst
Journal: Blood
Blood (2013) 122 (12): 2039–2046.
https://doi.org/10.1182/blood-2013-03-486647
Published: 2013
Includes: Supplemental data
Journal Articles

Targeting Menin-MLL Interaction to Inhibit MLL Fusion Oncoproteins in Leukemia

Jolanta Grembecka, PhD, Shihan He, PhD, Aibin Shi, PhD, Trupta Purohit, Andrew G. Muntean, PhD, Xiaoqin Li, Thomas Hartley, Duxin Sun, PhD, Jay L. Hess, MD, PhD, Tomasz Cierpicki, PhD
Journal: Blood
Blood (2011) 118 (21): 2497.
https://doi.org/10.1182/blood.V118.21.2497.2497
Published: 2011
Journal Articles

Risk Factors and Clinical Outcome of Central Nervous System (CNS) Leukemia In Patients with Acute Promyelocytic Leukemia (APL) on Long-Term Oral Arsenic Trioxide Maintenance.

Wing Y Au, Cyrus Kumana, MD, Yok lam Kwong, MD
Journal: Blood
Blood (2010) 116 (21): 1082.
https://doi.org/10.1182/blood.V116.21.1082.1082
Published: 2010
Journal Articles

Molecular Basis of Menin-MLL Interaction: Implication for Targeted Therapies in MLL Leukemias.

Jolanta Grembecka, Amalia Marie Belcher, Tomasz Cierpicki
Journal: Blood
Blood (2009) 114 (22): 3775.
https://doi.org/10.1182/blood.V114.22.3775.3775
Published: 2009
Journal Articles

SIGNIFICANCE of ABSOLUTE LYMPHOCYTE COUNT at RELAPSE as a PROGNOSTIC FACTOR in PATIENTS with T-CELL NON-HODGKIN'S LYMPHOMA.

Dae Ro Choi, M.D., Dok Hyun Yoon, M.D., Heui June Ahn, M.D., Yoojin Cho, M.D., Eun Kyoung Kim, M.D., Shin Kim, Jooryung Huh, M.D., Dae Ho Lee, M.D., Sang We Kim, M.D., Jung Shin Lee, M.D., Cheolwon Suh, M.D.
Journal: Blood
Blood (2009) 114 (22): 2939.
https://doi.org/10.1182/blood.V114.22.2939.2939
Published: 2009
Journal Articles

Menin regulates the function of hematopoietic stem cells and lymphoid progenitors

Ivan Maillard, Ya-Xiong Chen, Ann Friedman, Yuqing Yang, Anthony T. Tubbs, Olga Shestova, Warren S. Pear, Xianxin Hua
Journal: Blood
Blood (2009) 113 (8): 1661–1669.
https://doi.org/10.1182/blood-2008-01-135012
Published: 2009
Includes: Supplemental data
Journal Articles

The Menin Tumor Suppressor Functions as a Molecular Adapter That Tethers LEDGF to MLL Proteins in Leukemogenesis.

Akihiko Yokoyama, PhD, Michael Cleary, MD
Journal: Blood
Blood (2008) 112 (11): 1795.
https://doi.org/10.1182/blood.V112.11.1795.1795
Published: 2008
Journal Articles

Menin Regulates the Function of Lymphoid Progenitors and Hematopoietic Stem Cells.

Ivan Maillard, MD, PhD, Ya-Xiong Chen, PhD, Anthony T. Tubbs, Olga Shestova, PhD, Warren S. Pear, MD-PhD, Xianxin Hua, MD-PhD
Journal: Blood
Blood (2007) 110 (11): 1257.
https://doi.org/10.1182/blood.V110.11.1257.1257
Published: 2007
Journal Articles

Predictors of Survival in De Novo Cardiac Amyloidosis.

Raymond L. Comenzo, MD, Mathew Maurer, MD, Adam Cohen, MD, Hani Hassoun, MD, Ping Zhou, PhD, Ping Lu, PhD, Martin Fleisher, PhD, Daniel Lebovic, MD, Julie Feldstein, MD, Richard Steingart, MD, Stephen D. Nimer, MD
Journal: Blood
Blood (2007) 110 (11): 2870.
https://doi.org/10.1182/blood.V110.11.2870.2870
Published: 2007
Journal Articles

c-Myb Functions as a Co-Activator of MLL1 through Menin, and More Globally Affects Histone Methylation.

Shenghao Jin, PhD, Huiwu Zhao, Ph.D, Alan M. Gewirtz, MD
Journal: Blood
Blood (2007) 110 (11): 827.
https://doi.org/10.1182/blood.V110.11.827.827
Published: 2007
Journal Articles

c-Myb-Interacting Proteins and Their Functions.

Shenghao Jin, PhD, Huiwu Zhao, Ph.D., Alan M. Gewirtz, MD
Journal: Blood
Blood (2006) 108 (11): 1423.
https://doi.org/10.1182/blood.V108.11.1423.1423
Published: 2006
Journal Articles

Arsenic Trioxide in Mantle Cell Lymphoma.

Yok Lam Kwong, MD, Chit Chow, MPhil, Cyrus R. Kumana, MD, Gopesh Srivastava, PhD, Wing Yan Au, MD
Journal: Blood
Blood (2005) 106 (11): 4814.
https://doi.org/10.1182/blood.V106.11.4814.4814
Published: 2005
Journal Articles

The Menin Tumor Suppressor Protein Is an Essential Oncogenic Cofactor for MLL-Associated Leukemogenesis.

Akihiko Yokoyama, PhD, Tim Somervaille, MD, PhD, Michael L. Cleary, MD
Journal: Blood
Blood (2005) 106 (11): 665.
https://doi.org/10.1182/blood.V106.11.665.665
Published: 2005
Journal Articles

Leukemia Proto-Oncoprotein MLL Forms a SET1 like Complex with Menin to Regulate Hox Gene Expression.

Akihiko Yokoyama, Ph.D, Zhong Wang, Ph.D, Joanna Wysocka, Ph.D, Mrinmoy Sanyal, Ph.D, Deborah J. Aufiero, Issay Kitabayashi, Ph.D, Winship Herr, Ph.D, Michael L. Cleary, M.D
Journal: Blood
Blood (2004) 104 (11): 2550.
https://doi.org/10.1182/blood.V104.11.2550.2550
Published: 2004