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Journal Articles

Transcriptome Profiling of Glycosylation Genes Defines Correlation with E-Selectin Ligand Expression and Clinical Outcome in AML

Amanda R. Leonti, MS, Laura Pardo, Todd A. Alonzo, PhD, Robert B. Gerbing, Lisa Eidenschink Brodersen, PhD, Rhonda E. Ries, MA, Jenny L. Smith, MSc, MD, Quy Le, PhD, Richard Aplenc, MD PhD, E. Anders Kolb, MD, John L. Magnani, PhD, William E. Fogler, PhD, Michael R. Loken, PhD, Soheil Meshinchi, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 3772.
https://doi.org/10.1182/blood-2019-124525
Published: 2019
Journal Articles

IFNy Stimulation Induces Hematopoietic Stem Cell Homing and Niche Relocalization

Marcus A Florez, BS, Katie A Matatall, PhD, Laura Ortinau, PhD, Roman Jaksik, PhD, Marek Kimmel, PhD DSc, Dongsu Park, PhD, Katherine Y. King, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 3726.
https://doi.org/10.1182/blood-2019-130555
Published: 2019
Journal Articles

Latent Membrane Protein 1 Contributes to Deficient Cellular Immunity in NKTCL Patients

Xiaoyan Feng, Yue Song, Zhaoming Li, MD PhD, Xudong Zhang, Lugui Qiu, MD PhD, Mingzhi Zhang, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 3969.
https://doi.org/10.1182/blood-2019-128622
Published: 2019
Journal Articles

Novel Role of Raft-Associated Smoothened (SMO) in AKT Signal Regulation in Diffuse Large B Cell Lymphoma

Nitin Agarwal, PhD, Kranthi Kunkalla, Daniel Bilbao, PhD, Ralf Landgraf, PhD, Francisco Vega, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 3972.
https://doi.org/10.1182/blood-2019-121847
Published: 2019
Journal Articles

Characterization of Monoclonal Gammopathy of Undetermined Significance Progression to Multiple Myeloma through Meta-Analysis of GEO Data

Jihad Aljabban, MMSc, BA, David Chen, BS, Francesca Cottini, MD, Saad Syed, BS, Nabeal Aljabban, BS, Sharjeel Syed, BS, Tiffany Hughes, PhD, David Feldman, BS, Dexter Hadley, MD PhD, Don M. Benson, Jr., MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 4395.
https://doi.org/10.1182/blood-2019-129699
Published: 2019
Journal Articles

TJC4, a Differentiated Anti-CD47 Antibody with Novel Epitope and RBC Sparing Properties

Zhen Meng, PhD, Zhengyi Wang, PhD, Bingshi Guo, PhD, Wei Cao, PhD, Huaqiong Shen, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 4063.
https://doi.org/10.1182/blood-2019-122793
Published: 2019
Journal Articles

Single Cell Profiling of DNMT3A-Mutant Progenitors Reveals LY86 As a Novel Pre-Leukemia Marker and Potential Therapeutic Target

Mira Jeong, PhD, Sangbae Kim, PhD, Yumei Li, PhD, Rui Chen, PhD, Premal Lulla, MBBS, Margaret Goodell, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 2724.
https://doi.org/10.1182/blood-2019-123597
Published: 2019
Journal Articles

Safety and Preliminary Clinical Activity of REGN5458, an Anti-Bcma x Anti-CD3 Bispecific Antibody, in Patients with Relapsed/Refractory Multiple Myeloma

Dennis Cooper, MD, Deepu Madduri, MD, Suzanne Lentzsch, MD PhD, Sundar Jagannath, Jingjin Li, PhD, Anita Boyapati, PhD, Lieve Adriaens, PharmD, Dhruti Chokshi, BS, Min Zhu, PhD, Israel Lowy, MD PhD, David M. Weinreich, MD, George D. Yancopoulos, MD PhD, Manish Sharma, MD, Maria Karasarides, PhD, David Sternberg, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 3176.
https://doi.org/10.1182/blood-2019-126818
Published: 2019
Journal Articles

The First Functional HLA-a*01:01-Restricted EBV-LMP2-Specific T-Cell Receptors for TCR Gene Therapy of Patients with EBV-Associated Type II/III Malignancies

Wesley Huisman, MSc, Ilse Gille, Lieve E. van der Maarel, Lois Hageman, Rob C.M. de Jong, PhD, Derk Amsen, PhD, Fred Falkenburg, MD PhD, Inge Jedema, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 4448.
https://doi.org/10.1182/blood-2019-123736
Published: 2019
Journal Articles

Discovery of Novel IL3RA (CD123) Isoforms By Long Read Transcriptomics, Heterogeneous Expression Among AML Patient Cohorts and the Implications for Anti-CD123 Therapeutics

Jason G Underwood, PhD BA, Jenny L. Smith, MSc, MD, Lindsey F. Call, B.A., Elizabeth Tseng, PhD, Tiffany A. Hylkema, BS, Rhonda E. Ries, MA, Amanda R. Leonti, MS, Jason E. Farrar, MD, Timothy Junius Triche, Jr., PhD, Soheil Meshinchi, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 4658.
https://doi.org/10.1182/blood-2019-131508
Published: 2019
Journal Articles

Adhesion-Mediated Multiple Myeloma (MM) Disease Progression: Junctional Adhesion Molecule a Enhances Angiogenesis and Multiple Myeloma Dissemination and Predicts Poor Survival

Antonio Giovanni Solimando, MD, Matteo Claudio Da Via', MD, Patrizia Leone, Giorgio Croci, Paola Borrelli, Paula Tabares Gaviria, Andreas Brandl, PhD, Giuseppe Di Lernia, Francesco Paolo Bianchi, Silvio Tafuri, Umair Munawar, MSc, Torsten Steinbrunn, Alessandra Balduini, MD, Assunta Melaccio, Hilka Rauert-Wunderlich, Katharina Schmiedgen, Hannah Manz, Paolo Ditonno, Roberto Ria, MD, Erik Henke, Carolina Terragna, Wolfram Klapper, Nora Trinks, Ulrich Terpitz, Giacomo Corleone, Leo Rasche, MD, Andreas Rosenwald, MD, Martin Kortuem, Michele Cavo, Domenico Ribatti, MD, Vito Racanelli, Hermann Einsele, MD, Angelo Vacca, MD PhD, Andreas Beilhack, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 855.
https://doi.org/10.1182/blood-2019-126674
Published: 2019
Journal Articles

The Multidrug Transporter MRP4/ABCC4 Involved in the Leukemia Clinical Course Specifies the Novel PEL Human Blood Group System

Slim Azouzi, PhD, Mahmoud Mikdar, MSc, Patricia Hermand-Tournamille, PhD, Emilie-Fleur Gautier, PhD, Virginie Salnot, PhD, Alexandra Willemetz, MSc, Gaël Nicolas, PhD, Cedric Vrignaud, MSc, Alexandre Raneri, Patrick Mayeux, PhD, Christine Bole-Feysot, PhD, Patrick Nitschke, PhD, Jean-Pierre Cartron, PhD, Yves Colin Aronovicz, PhD, Olivier Hermine, Gabriele Jedlitschky, PhD, Marc Cloutier, PhD, Jessica Constanzo-Yanez, Carole Ethier, Nancy Robitaille, MD, Maryse St-Louis, Caroline Le Van Kim, PhD, Thierry Peyrard, PharmD/PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 715.
https://doi.org/10.1182/blood-2019-124082
Published: 2019
Journal Articles

Exome Sequencing of Relapsed Multiple Myeloma Combined with Pooled CRISPR/Cas9 Screens Identifies Gene Mutations Associated with Drug-Specific Resistance

Stephan Bohl, Laura K. Schmalbrock, MD, Imke Bauhuf, Anna Dolnik, Tamara J. Blätte, MSc, Stefanie Lindner, Dr., Tatjana Meyer, MSc, BSc, Sarah Knödler, Denise Miller, Miriam Kull, Christian Langer, MD, Hartmut Döhner, MD, Dirk Heckl, PhD, Lars Bullinger, Jan Krönke, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 809.
https://doi.org/10.1182/blood-2019-131245
Published: 2019
Journal Articles

Protein Translocation Inhibitors Overcome Cytokine-Induced Glucocorticoid Resistance in T-Cell Acute Lymphoblastic Leukemia

Lauren K. Meyer, Cristina Delgado-Martin, PhD, Phillip P. Sharp, PhD, Dustin McMinn, PhD, Christopher J. Kirk, PhD, Jack Taunton, PhD, Michelle L. Hermiston, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 805.
https://doi.org/10.1182/blood-2019-127537
Published: 2019
Journal Articles

Functionally Distinct Subsets of Monocytes in Mouse and Human Blood

Catherine S Rhee, PhD, Elizabeth W Scadden, Chea L Phillip, Bum-Kyu Lee, PhD, Meeta Mistry, Friedrich F Hoyer, MD, Hiroki Kato, MD PhD, Giovanna Mantica, Jonghwan Kim, PhD, Matthias Nahrendorf, PhD, Michael K Mansour, MD PhD, David B Sykes, MD PhD, David T. Scadden, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 438.
https://doi.org/10.1182/blood-2019-124054
Published: 2019
Journal Articles

Blocking Protein Secretion with Novel Small Molecule Inhibitors of Sec61 Represents a Potential Treatment Strategy Against Hematologic Malignancies

Eric Lowe, BS, Andrea R Fan, PhD, Jing Jiang, Henry W. B. Johnson, PhD, Christopher J. Kirk, PhD, Dustin McMinn, PhD, Tony Muchamuel, MS, Yu Qian, PhD, Brian B. Tuch, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 408.
https://doi.org/10.1182/blood-2019-123782
Published: 2019
Journal Articles

Circulating Extracellular Vesicles Induce Chimeric Antigen Receptor T Cell Dysfunction in Chronic Lymphocytic Leukemia (CLL)

Michelle J. Cox, Fabrice Lucien-Matteoni, PhD, Reona Sakemura, MD PhD, Justin C. Boysen, Yohan Kim, MS, Michael J. Hansen, Claudia Manriquez Roman, Erin E. Tapper, Sydney B. Crotts, Kendall J. Schick, Mehrdad Hefazi, MD, Paulina Roman Moreno, MD, Michael W. Ruff, MD, Sameer A. Parikh, MD, Neil E. Kay, MD, Saad S. Kenderian, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 679.
https://doi.org/10.1182/blood-2019-125272
Published: 2019
Journal Articles

Serologic Characterization of Antibodies in Patients Experiencing Piperacillin-Induced Immune Thrombocytopenia

Mark Rasmussen, Daniel W. Bougie, PhD, Gregory H. Denomme, Richard H. Aster, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 1078.
https://doi.org/10.1182/blood-2019-130966
Published: 2019
Journal Articles

Comparative Analysis of sSLAMF7, sBCMA, and M-Protein As Prognostic, Predictive, and Pharmacodynamic Biomarkers in Relapsed/Refractory Multiple Myeloma Treated with Pomalidomide and Dexamethasone +/- Elotuzumab

Ann Forslund, PhD, Hao Tang, Chunzhe Duan, Mihaela Popa-McKiver, PhD, James R. Berenson, MD, Michael Robbins, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 1853.
https://doi.org/10.1182/blood-2019-128760
Published: 2019
Journal Articles

Profiling the Cell Surface Landscape of Proteasome Inhibitor-Treated and -Resistant Multiple Myeloma to Guide Immunotherapy Targeting, Diagnosis, and Biology

Ian Ferguson, BA, Yu-Hsiu T. Lin, BA, Sami Tuomivaara, PhD, Jeffrey L. Wolf, MD, Thomas G. Martin, III, MD, Sandy W. Wong, MD, Nina D. Shah, MD, Christoph Driessen, MD, Brian G. Van Ness, PhD, Arun P. Wiita, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 1803.
https://doi.org/10.1182/blood-2019-131681
Published: 2019