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Journal Articles

Mammalian VPS45 orchestrates trafficking through the endosomal system

Laura Frey, Natalia Ziętara, Marcin Łyszkiewicz, Benjamin Marquardt, Yoko Mizoguchi, Monika I. Linder, Yanshan Liu, Florian Giesert, Wolfgang Wurst, Maik Dahlhoff, Marlon R. Schneider, Eckhard Wolf, Raz Somech, Christoph Klein
Journal: Blood
Blood (2021) 137 (14): 1932–1944.
https://doi.org/10.1182/blood.2020006871
Published: 2021
Includes: Multimedia, Supplemental data
Journal Articles

Developmental trajectory of prehematopoietic stem cell formation from endothelium

Qin Zhu, Peng Gao, Joanna Tober, Laura Bennett, Changya Chen, Yasin Uzun, Yan Li, Elizabeth D. Howell, Melanie Mumau, Wenbao Yu, Bing He, Nancy A. Speck, Kai Tan
Journal: Blood
Blood (2020) 136 (7): 845–856.
https://doi.org/10.1182/blood.2020004801
Published: 2020
Includes: Supplemental data
Journal Articles

Factor VIII exhibits chaperone-dependent and glucose-regulated reversible amyloid formation in the endoplasmic reticulum

Juthakorn Poothong, Anita Pottekat, Marina Siirin, Alexandre Rosa Campos, Adrienne W. Paton, James C. Paton, Jacqueline Lagunas-Acosta, Zhouji Chen, Mark Swift, Niels Volkmann, Dorit Hanein, Jing Yong, Randal J. Kaufman
Journal: Blood
Blood (2020) 135 (21): 1899–1911.
https://doi.org/10.1182/blood.2019002867
Published: 2020
Includes: Supplemental data
Journal Articles

Wdr26 regulates nuclear condensation in developing erythroblasts

Ru Zhen, Chingyee Moo, Zhenzhen Zhao, Mengying Chen, He Feng, Xiaojun Zheng, Liang Zhang, Jiahai Shi, Caiyong Chen
Journal: Blood
Blood (2020) 135 (3): 208–219.
https://doi.org/10.1182/blood.2019002165
Published: 2020
Includes: Supplemental data
Journal Articles

The Samd14 Sterile Alpha Motif Domain Promotes Stress-Induced Cellular Signaling and Survival

Kyle J Hewitt, PhD, Suhita Ray, Srinivas Chava, PhD, Linda Chee
Journal: Blood
Blood (2019) 134 (Supplement_1): 1184.
https://doi.org/10.1182/blood-2019-131228
Published: 2019
Journal Articles

Targeting Nicotinamide Adenine Dinucleotide (NAD) Glycohydrase Activity of CD38 Exerts Anti-Myeloma Effect Accompanying Intracellular NAD Elevation

Saki Kushima, Takayuki Sasano, Masao Matsuoka, MD PhD, Hiroyuki Hata, MD PhD, Yawara Kawano, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 1810.
https://doi.org/10.1182/blood-2019-123624
Published: 2019
Journal Articles

Modulation of Thrombin-Induced Platelet Activation By Defibrotide

Kristin N. Maher, MD PhD, Xu Han, BS, MS, Keith B. Neeves, PhD, Marvin T. Nieman, PhD, Jorge Di Paola, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 3614.
https://doi.org/10.1182/blood-2019-125945
Published: 2019
Journal Articles

RASA3 Is Essential for Early Mammalian Hematopoiesis and Modulates ERK Signaling in Terminal Erythropoiesis

Elena C. Brindley, BS, Raymond F. Robledo, PhD, Steven L. Ciciotte, MS, Joel H. Graber, PhD, Yue Zhao, Emily Hartman, BS, Julien Papoin, MS, Lionel Blanc, PhD, Luanne L. Peters, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 3505.
https://doi.org/10.1182/blood-2019-130328
Published: 2019
Journal Articles

YAP and TAZ in Fibroblastic Reticular Cells Support Hematopoiesis and Retention of Lymphocytes in Lymph Nodes

Hyunsoo Cho, MD PhD, Yu Ri Kim, MD, Jieun Jang, MD, Haerim Chung, MD, Soo-Jeong Kim, Sung Yong Choi, Bae Hosung, Ralf Adams, Burkhard Ludewig, PhD, Jin Seok Kim, MD PhD, June-Won Cheong, MD PhD, Yoo Hong Min, MD PhD, Gou Young Koh
Journal: Blood
Blood (2019) 134 (Supplement_1): 3595.
https://doi.org/10.1182/blood-2019-124625
Published: 2019
Journal Articles

Superoxide Drives PI3 Kinase Mediated Mitochondria Transfer from the Bone Marrow Microenvironment to Hematopoietic Stem Cells in Response to Salmonella Typhimurium

Jayna J Mistry, BSc, Christopher R Marlein, PhD, Jamie A Moore, BSc, MSc, Charlotte Hellmich, MBBChir, Iain Macauley, PhD BSc, Naiara Beraza, PhD, Yu Sun, BSc, MSc, PhD, Adam Morfakis, BSc, Angela Patterson, PhD, Rebecca H Horton, Devina Divekar, Christopher J Morris, PhD, Anna Haestier, Bsc, PgD MBBS, MRCOG, Federica Di Palma, PhD, Kristian M Bowles, MBBS, PhD, Stuart A Rushworth, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 2490.
https://doi.org/10.1182/blood-2019-128241
Published: 2019
Journal Articles

Potently Cytotoxic Natural Killer Cell Potential Initially Emerges from Erythro-Myeloid Progenitors during Mammalian Development

Carissa Dege, PhD, Katherine H Fegan, MS, J Philip Creamer, IV, BA,BS, Melissa M Berrien-Elliott, PhD, Stephanie A. Luff, PhD, Julia A Wagner, PhD, Paul D. Kingsley, PhD, Kathleen E. McGrath, PhD, Todd A Fehniger, MD PhD, James Palis, MD, Christopher M. Sturgeon, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 2464.
https://doi.org/10.1182/blood-2019-130347
Published: 2019
Journal Articles

Coagulation FXIII-a Protein Expression Defines Three Novel Sub-Populations in Pediatric B-Cell Progenitor Acute Lymphoblastic Leukemia Characterized By Distinct Gene Expression Signatures

Katalin Gyurina, MSc, BSc, Bettina Kárai, MD PhD, Anikó Ujfalusi, MD PhD, Zsuzsanna Hevessy, MD PhD, Gábor Barna, PhD, Pál Jáksó, MD PhD, Gyönygi Pálfi-Mészáros, Szilárd Páliska, PhD, Beáta Scholtz, PhD, János Kappelmayer, MD PhD DSc, Gábor Zahuczky, PhD, Csongor Kiss, MD PhD DSc
Journal: Blood
Blood (2019) 134 (Supplement_1): 2523.
https://doi.org/10.1182/blood-2019-124333
Published: 2019
Journal Articles

PKR-like Endoplasmic Reticulum Kinase Mediates Apoptosis Induced By Pharmacological AMP-Activated Protein Kinase Activation in Acute Myeloid Leukemia

Laury Poulain, PhD, Adrien Grenier, MD PhD, Johanna Mondesir, MD, Arnaud Jacquel, PhD, Claudie Bosc, Lucille Stuani, PhD, Rudy Birsen, MD, Sarah Mouche, Justine Decroocq, MD, Fetta Mazed, PhD, Benoit Viollet, PhD, Patrick Auberger, PhD, Pierre Sujobert, MD PhD, Didier Bouscary, MD PhD, Jean-Emmanuel Sarry, PhD, Jerome Tamburini, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 2552.
https://doi.org/10.1182/blood-2019-123364
Published: 2019
Journal Articles

Mutant ASXL1 Disrupts Paraspeckle Formation through Aberrant Interaction with Nono in Hematopoietic Cells

Yamamoto Keita, MD, Susumu Goyama, MD PhD, Shuhei Asada, MD PhD, Takeshi Fujino, MD, Tomofusa Fukuyama, MD PhD, Yosuke Tanaka, MD, Ayana Kon, MD PhD, Yasuhito Nannya, MD PhD, Seishi Ogawa, MD PhD, Reina Onoguchi, PhD, Nobuyoshi Akimitsu, PhD, Toshio Kitamura, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 2514.
https://doi.org/10.1182/blood-2019-125472
Published: 2019
Journal Articles

Loss of METTL3 Mediated m6A RNA Modification Results in Double-Stranded RNA Induced Innate Immune Response and Hematopoietic Failure

Yimeng Gao, PhD, Radovan Vasic, MD, Yuanbin Song, MD, Rhea Teng, B.Sc., Rana Gbyli, MS, Giulia Biancon, PhD, Raman Nelakanti, B.Sc., Eriko Kudo, B.Sc., Wei Liu, PhD, Anastasia Ardasheva, BS, Xiaoying Fu, MD, Xiaman Wang, MD PhD, Poorval Joshi, PhD, Burak Dura, PhD, Veronica Lee, Gabriella Viero, PhD, Akiko Iwasaki, PhD, Rong Fan, PhD, Andrew Xiao, PhD, Richard Flavell, PhD, Hua-Bing Li, PhD, Toma Tebaldi, PhD, Stephanie Halene, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 450.
https://doi.org/10.1182/blood-2019-130442
Published: 2019
Journal Articles

Transcription Factor Induction of Ectopic Vascular Blood Stem Cell Niches In Vivo

Elliott J. Hagedorn, PhD, Julie R. Perlin, PhD, Rebecca J. Freeman, BS, Clara Mao, BS, Inés Fernández-Maestre, BS, Madeleine L. Daily, B.S., Christopher R. D'Amato, B.S., Samuel J. Wattrus, B.S., Tianxiao Han, BS, Michael J. Fairchild, PhD, Raquel Riquelme, Brian Li, B.S., Shelby E. Redfield, B.S., Samantha H. Collins, B.S., Asher Lichtig, BS, Song Yang, PhD, Yi Zhou, Balvir Kunar, Jesus M Gomez-Salinero, PhD, Theresa T. Dinh, PhD, Junliang Pan, MD PhD, Karoline Holler, B.S., Eugene Butcher, Alexander Van Oudenaarden, Shahin Rafii, MD, Jan Philipp Junker, PhD, Leonard I Zon, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 525.
https://doi.org/10.1182/blood-2019-127219
Published: 2019
Journal Articles

Genetic Duplication of Tissue Factor Leads to Partial Specialization of Function in Zebrafish

Steven Grzegorski, BA, Divyani Paul, BS, James H. Morrissey, PhD, Jordan A. Shavit, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 486.
https://doi.org/10.1182/blood-2019-131980
Published: 2019
Journal Articles

Cells Deficient in the Shwachman-Diamond Syndrome Protein SBDS or the Diamond-Blackfan Anemia Protein RPS19 Have Impaired Homologous Recombination

Elif Asik, PhD, Nimrat Chatterjee, PhD, Alison A. Bertuch, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 104.
https://doi.org/10.1182/blood-2019-128953
Published: 2019
Journal Articles

A Novel CD19-Anti-CD20 Bridging Protein Prevents and Reverses CD19-Negative Relapse from CAR19 T Cell Treatment In Vivo

Paul Rennert, PhD, Lihe Su, PhD, Fay Dufort, PhD, Alyssa Birt, MS, Tom Sanford, Lan Wu, PhD, Christine Ambrose, PhD, Roy Lobb, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 252.
https://doi.org/10.1182/blood-2019-130654
Published: 2019
Journal Articles

Genetic Vulnerabilities of DNMT3A R882H in Myeloid Malignancies

Malgorzata Gozdecka, PhD, Monika Dudek, MSc, Konstantinos Tzelepis, Aristi Damaskou, MSc, Vijay Baskar, PhD, Penny Wright, Graham Duddy, Eshwar Meduri, PhD, Milena Mazan, PhD, Kosuke Yusa, PhD, Brian J. P. Huntly, PhD MRCP, MB, FRCPath, George S. Vassiliou, FRCPath, MRCP, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 111.
https://doi.org/10.1182/blood-2019-126505
Published: 2019