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Journal Articles

Inducible MyD88/CD40 (iMC) Enhances Proliferation and Survival of Tumor-Specific TCR-Modified T Cells and Improves Anti-Tumor Efficacy in Myeloma

Tsvetelina Pentcheva-Hoang, PhD, David Torres, Tania Rodriguez, PhD, Ana Korngold, PhD, An Lu, Jeannette Crisostomo, Annemarie Moseley, MD PhD, Lorenz Jahn, Mirjam H.M. Heemskerk, PhD, Kevin M Slawin, MD, David M Spencer, PhD, Aaron E Foster, PhD

Blood (2016) 128 (22): 4550.

https://doi.org/10.1182/blood.V128.22.4550.4550

Published: 2016

Journal Articles

T Cell Receptor Gene Therapy Targeting the Intracellular Transcription Factor Bob1 for the Treatment of Multiple Myeloma and Other B Cell Malignancies

Lorenz Jahn, Renate S. Hagedoorn, Pleun Hombrink, PhD, Michel G.D. Kester, Dirk M. van der Steen, Chopie Hassan, Marjolein P. Schoonakker, Erwin van der Pijl, Peter A. van Veelen, PhD, J.H. Frederik Falkenburg, MD PhD, Mirjam H.M. Heemskerk, PhD

Blood (2015) 126 (23): 3002.

https://doi.org/10.1182/blood.V126.23.3002.3002

Published: 2015

Journal Articles

Therapeutic targeting of the BCR-associated protein CD79b in a TCR-based approach is hampered by aberrant expression of CD79b

Lorenz Jahn, Pleun Hombrink, Chopie Hassan, Michel G. D. Kester, Dirk M. van der Steen, Renate S. Hagedoorn, J. H. Frederik Falkenburg, Peter A. van Veelen, Mirjam H. M. Heemskerk

Blood (2015) 125 (6): 949–958.

https://doi.org/10.1182/blood-2014-07-587840

Published: 2015

Includes: Supplemental data

Journal Articles

T Cell Receptors Specific for the Intracellular Transcription Factor Bob1 Allow Efficient Targeting of Human B Cell Leukemia and Multiple Myeloma

Lorenz Jahn, Pleun Hombrink, Michel G.D. Kester, Dirk M. van der Steen, Renate S. Hagedoorn, Chopie Hassan, Marjolein P. Schoonakker, Erwin van der Pijl, Peter A. van Veelen, PhD, J.H. Frederik Falkenburg, MD PhD, Mirjam H.M. Heemskerk, PhD

Blood (2014) 124 (21): 3832.

https://doi.org/10.1182/blood.V124.21.3832.3832

Published: 2014

Journal Articles

Identification and Monitoring of Pathogenic T Cell Clones Using Deep TCR Sequencing in T-Large Granular Lymphocyte Leukemia and Aplastic Anemia

Michael J. Clemente, Bartlomiej Przychodzen, BS, Hideki Makishima, Manuel G. Afable, II, MD, Marcin W Wlodarski, Alan E. Lichtin, MD, Jaroslaw P. Maciejewski, MD, PhD

Blood (2012) 120 (21): 3477.

https://doi.org/10.1182/blood.V120.21.3477.3477

Published: 2012

Journal Articles

HLA Associated Susceptibility to EBV+ Hodgkin Lymphoma: No Correlation with Infectious Mononucleosis or Number of Circulating EBV+ B Cells.

Arjan Diepstra, MD PhD, Alison M Leese, Annette Pachnio, PhD, Andrew I Bell, PhD, Bouke Hepkema, PhD, Anke Van Den Berg, PhD, Paul AH Moss, MD PhD, Steven P Lee, PhD, Alan B Rickinson, PhD

Blood (2012) 120 (21): 2635.

https://doi.org/10.1182/blood.V120.21.2635.2635

Published: 2012

Journal Articles

T Cell Receptor Repertoire Landscape Mapping: A Novel Paradigm for T Cell Mediated Autoimmune Disorders Based on Deep Vβ Chain Sequencing

Michael J Clemente, Bartlomiej Przychodzen, Hideki Makishima, MD, PhD, Manuel G Afable, II, MD, Alan E. Lichtin, MD, Jaroslaw P. Maciejewski, MD, PhD

Blood (2011) 118 (21): 1341.

https://doi.org/10.1182/blood.V118.21.1341.1341

Published: 2011

Journal Articles

Cytotoxic T Cells Specific for Adenovirus, BK Virus, Cytomegalovirus, Epstein Barr Virus and Varicella Zoster Virus Produced for Clinical Use In Immune Reconstitution Post Allogeneic Stem Cell Transplantation

Emily Blyth, Leighton Clancy, Shiva Gaundar, Renee Simms, David Gottlieb

Blood (2010) 116 (21): 830.

https://doi.org/10.1182/blood.V116.21.830.830

Published: 2010

Journal Articles

A CD8+ T-Cell Clone Directed Against AML Blasts that Recognizes a Tumor Specific Antigen Expressed Also by Solid Tumors

Angela Rita Elia, PhD, Paola Circosta, PhD, Russo Vincenzo, PhD, Lia Mele, PhD, Bernardino Allione, PhD, Corrado Tarella, PhD, Alessandro Cignetti

Blood (2010) 116 (21): 4289.

https://doi.org/10.1182/blood.V116.21.4289.4289

Published: 2010

Journal Articles

Myeloid leukemic progenitor cells can be specifically targeted by minor histocompatibility antigen LRH-1–reactive cytotoxic T cells

Wieger J. Norde, Ingrid M. Overes, Frans Maas, Hanny Fredrix, Johanna C. M. Vos, Michel G. D. Kester, Robbert van der Voort, Inge Jedema, J. H. Frederik Falkenburg, Anton V. Schattenberg, Theo M. de Witte, Harry Dolstra

Blood (2009) 113 (10): 2312–2323.

https://doi.org/10.1182/blood-2008-04-153825

Published: 2009

Includes: Supplemental data

Journal Articles

Adoptive Transfer and Consequential Selective Reconstitution of Streptamer-Selected Cytomegalovirus-Specific CD8+ T Cells Leads to Enduring Virus Clearance in Patients after Allogeneic Stem Cell Transplantation

Anita Schmitt, Torsten Tonn, Dirk Busch, Götz Grigoleit, Hermann Einsele, Marcus Odendahl, Lothar Germeroth, Mark Ringhoffer, Simone Ringhoffer, Markus Wiesneth, Detlef Michel, Thomas Mertens, Markus Rojewski, Martin Marx, Stephanie Harsdorf, Hartmut Döhner, Erhard Seifried, Donald Bunjes, Michael Schmitt

Blood (2008) 112 (11): 1181.

https://doi.org/10.1182/blood.V112.11.1181.1181

Published: 2008

Journal Articles

Donor Lymphocytes Stimulated with CMV pp65 Gene Modified Dendritic Cells for Prophylaxis of CMV Following Allogeneic Haemopoietic Stem Cell Transplantation.

Kenneth P. Micklethwaite, MBBS, Leighton E. Clancy, B.Sc, PhD, Upinder Sandher, B.Sc, Elizabeth Snape, BNURS, Kenneth Francis Bradstock, MD, PhD, David J. Gottlieb, MD

Blood (2007) 110 (11): 2989.

https://doi.org/10.1182/blood.V110.11.2989.2989

Published: 2007

Journal Articles

Streptamer Technology for the Assessment of CMVpp65 Specific CD8+ T Cell Frequencies and for the Adoptive T Cell Transfer to Post-Transplant Patients.

Anita Schmitt, MD, Junxia Yao, MD, Hermann Einsele, PhD, MD, Ulrich Grigoleit, MD, Dirk Busch, PhD, MD, Manuel Odendahl, MD, Lothar Germeroth, PhD, Torsten Tonn, PhD, MD, Markus Wiesneth, MD, Markus Rojewski, MD, Clemens Bechter, Stefanie von Harsdorf, MD, Hartmut Dohner, PhD, MD, Donald Bunjes, PhD, MD, Michael Schmitt, PhD, MD

Blood (2007) 110 (11): 1964.

https://doi.org/10.1182/blood.V110.11.1964.1964

Published: 2007

Journal Articles

Aberrant Expression in Human Epithelial Cancers of the P2X5-Encoded Minor Histocompatibility Antigen LRH-1: Implications for Graft-Versus-Tumor Immunity Against Solid Tumors.

Harry Dolstra, PhD, Henriette Levenga, MD, Ingrid Overes, MSc, Johanna C.M. Vos, BSc, Agnes van Horssen-Zoetbrood, BSc, Robbert van der Voort, PhD, Pieter de Mulder, MD, PhD, T.M. de Witte, MD, PhD

Blood (2007) 110 (11): 1795.

https://doi.org/10.1182/blood.V110.11.1795.1795

Published: 2007

Journal Articles

Human CD34+ Myeloid Leukemic Progenitor Cells Are Susceptible to Lysis by Minor Histocompatibility Antigen LRH-1-Specific Cytotoxic T Lymphocytes.

Harry Dolstra, PhD, Ingrid Overes, Inge Jedema, PhD, Annemieke Vos, Agnes van Horssen-Zoetbrood, Wieger Norde, Robbert van der Voort, PhD, J.H. Frederik Falkenburg, MD, PhD, Anton V. Schattenberg, MD, PhD, T.M. de Witte, MD, PhD

Blood (2006) 108 (11): 134.

https://doi.org/10.1182/blood.V108.11.134.134

Published: 2006

Journal Articles

Identification of the angiogenic endothelial-cell growth factor-1/thymidine phosphorylase as a potential target for immunotherapy of cancer

Elisabeth H. Slager, M. Willy Honders, Edith D. van der Meijden, Simone A. P. van Luxemburg-Heijs, Freke M. Kloosterboer, Michel G. D. Kester, Inge Jedema, W. A. Erik Marijt, M. Ron Schaafsma, Roel Willemze, J. H. Frederik Falkenburg

Blood (2006) 107 (12): 4954–4960.

https://doi.org/10.1182/blood-2005-09-3883

Published: 2006

Journal Articles

Analysis of EBV-Specific T Cell Responses in Transplant Recipients with PTLD.

Kathrin Sebelin, Antje Meier, Matthias Papp-Vary, MD, Stefan Oertel, MD, Antonio Pezzutto, MD, Bernd Doerken, MD, Hanno Riess, MD, Marion Subklewe, MD

Blood (2005) 106 (11): 1915.

https://doi.org/10.1182/blood.V106.11.1915.1915

Published: 2005

Journal Articles

Re-Engineering γ δ T Cells by α β T Cell Receptor Gene Transfer Creates Potent Effector Cells with Anti-Leukemic Reactivity.

Lars T. van der Veken, Renate S. Hagedoorn, Marleen M. van Loenen, Roel Willemze, J.H. Frederik Falkenburg, Mirjam H.M. Heemskerk

Blood (2005) 106 (11): 1288.

https://doi.org/10.1182/blood.V106.11.1288.1288

Published: 2005

Journal Articles

Autologous CMV-Specific T Cells as Effector Cells in Immunotherapy of B Cell Chronic Lymphocytic Leukemia.

Arnon P. Kater, MD, Esther E.B.M Remmerswaal, Martijn A. Nolte, PhD, Eric Eldering, PhD, Rene A.W van Lier, MD. PhD, Marinus H.J van Oers, MD PhD

Blood (2004) 104 (11): 2512.

https://doi.org/10.1182/blood.V104.11.2512.2512

Published: 2004

Journal Articles

Transfection of Dendritic Cells with In Vitro Transcribed RNA Induces Polyclonal CMV-Specific CD8+ and CD4+ Mediated T Cell Responses.

Annkristin Heine, MB, Tobias Holderried, MB, Frank Grünebach, PhD, Silke Appel, PhD, Markus M. Weck, MS, Volker L. Reichardt, MD, Peter Brossart, MD

Blood (2004) 104 (11): 1354.

https://doi.org/10.1182/blood.V104.11.1354.1354

Published: 2004

NARROW

Inducible MyD88/CD40 (iMC) Enhances Proliferation and Survival of Tumor-Specific TCR-Modified T Cells and Improves Anti-Tumor Efficacy in Myeloma

T Cell Receptor Gene Therapy Targeting the Intracellular Transcription Factor Bob1 for the Treatment of Multiple Myeloma and Other B Cell Malignancies

Therapeutic targeting of the BCR-associated protein CD79b in a TCR-based approach is hampered by aberrant expression of CD79b

T Cell Receptors Specific for the Intracellular Transcription Factor Bob1 Allow Efficient Targeting of Human B Cell Leukemia and Multiple Myeloma

Identification and Monitoring of Pathogenic T Cell Clones Using Deep TCR Sequencing in T-Large Granular Lymphocyte Leukemia and Aplastic Anemia

HLA Associated Susceptibility to EBV+ Hodgkin Lymphoma: No Correlation with Infectious Mononucleosis or Number of Circulating EBV+ B Cells.

T Cell Receptor Repertoire Landscape Mapping: A Novel Paradigm for T Cell Mediated Autoimmune Disorders Based on Deep Vβ Chain Sequencing

Cytotoxic T Cells Specific for Adenovirus, BK Virus, Cytomegalovirus, Epstein Barr Virus and Varicella Zoster Virus Produced for Clinical Use In Immune Reconstitution Post Allogeneic Stem Cell Transplantation

A CD8+ T-Cell Clone Directed Against AML Blasts that Recognizes a Tumor Specific Antigen Expressed Also by Solid Tumors

Myeloid leukemic progenitor cells can be specifically targeted by minor histocompatibility antigen LRH-1–reactive cytotoxic T cells

Adoptive Transfer and Consequential Selective Reconstitution of Streptamer-Selected Cytomegalovirus-Specific CD8+ T Cells Leads to Enduring Virus Clearance in Patients after Allogeneic Stem Cell Transplantation

Donor Lymphocytes Stimulated with CMV pp65 Gene Modified Dendritic Cells for Prophylaxis of CMV Following Allogeneic Haemopoietic Stem Cell Transplantation.

Streptamer Technology for the Assessment of CMVpp65 Specific CD8+ T Cell Frequencies and for the Adoptive T Cell Transfer to Post-Transplant Patients.

Aberrant Expression in Human Epithelial Cancers of the P2X5-Encoded Minor Histocompatibility Antigen LRH-1: Implications for Graft-Versus-Tumor Immunity Against Solid Tumors.

Human CD34+ Myeloid Leukemic Progenitor Cells Are Susceptible to Lysis by Minor Histocompatibility Antigen LRH-1-Specific Cytotoxic T Lymphocytes.

Identification of the angiogenic endothelial-cell growth factor-1/thymidine phosphorylase as a potential target for immunotherapy of cancer

Analysis of EBV-Specific T Cell Responses in Transplant Recipients with PTLD.

Re-Engineering γ δ T Cells by α β T Cell Receptor Gene Transfer Creates Potent Effector Cells with Anti-Leukemic Reactivity.

Autologous CMV-Specific T Cells as Effector Cells in Immunotherapy of B Cell Chronic Lymphocytic Leukemia.

Transfection of Dendritic Cells with In Vitro Transcribed RNA Induces Polyclonal CMV-Specific CD8+ and CD4+ Mediated T Cell Responses.

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American Society of Hematology

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American Society of Hematology

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