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Journal Articles

TCR targeting hematopoiesis to cure leukemia

J. H. Frederik Falkenburg, Mirjam H. M. Heemskerk

Blood (2024) 144 (10): 1031–1033.

https://doi.org/10.1182/blood.2024024972

Published: 2024

Journal Articles

TCR-based therapy for multiple myeloma and other B-cell malignancies targeting intracellular transcription factor BOB1

Lorenz Jahn, Pleun Hombrink, Renate S. Hagedoorn, Michel G. D. Kester, Dirk M. van der Steen, Tania Rodriguez, Tsvetelina Pentcheva-Hoang, Arnoud H. de Ru, Marjolein P. Schoonakker, Miranda H. Meeuwsen, Marieke Griffioen, Peter A. van Veelen, J. H. Frederik Falkenburg, Mirjam H. M. Heemskerk

Blood (2017) 129 (10): 1284–1295.

https://doi.org/10.1182/blood-2016-09-737536

Published: 2017

Includes: Supplemental data

Journal Articles

Therapeutic targeting of the BCR-associated protein CD79b in a TCR-based approach is hampered by aberrant expression of CD79b

Lorenz Jahn, Pleun Hombrink, Chopie Hassan, Michel G. D. Kester, Dirk M. van der Steen, Renate S. Hagedoorn, J. H. Frederik Falkenburg, Peter A. van Veelen, Mirjam H. M. Heemskerk

Blood (2015) 125 (6): 949–958.

https://doi.org/10.1182/blood-2014-07-587840

Published: 2015

Includes: Supplemental data

Journal Articles

TCR-transgenic lymphocytes specific for HMMR/Rhamm limit tumor outgrowth in vivo

Stefani Spranger, Irmela Jeremias, Susanne Wilde, Matthias Leisegang, Lilian Stärck, Barbara Mosetter, Wolfgang Uckert, Mirjam H. M. Heemskerk, Dolores J. Schendel, Bernhard Frankenberger

Blood (2012) 119 (15): 3440–3449.

https://doi.org/10.1182/blood-2011-06-357939

Published: 2012

Includes: Supplemental data

Journal Articles

Allo-HLA–reactive T cells inducing graft-versus-host disease are single peptide specific

Avital L. Amir, Dirk M. van der Steen, Renate S. Hagedoorn, Michel G. D. Kester, Cornelis A. M. van Bergen, Jan W. Drijfhout, Arnoud H. de Ru, J. H. Frederik Falkenburg, Peter A. van Veelen, Mirjam H. M. Heemskerk

Blood (2011) 118 (26): 6733–6742.

https://doi.org/10.1182/blood-2011-05-354787

Published: 2011

Journal Articles

Allo-HLA reactivity of virus-specific memory T cells is common

Avital L. Amir, Lloyd J. A. D'Orsogna, Dave L. Roelen, Marleen M. van Loenen, Renate S. Hagedoorn, Renate de Boer, Menno A. W. G. van der Hoorn, Michel G. D. Kester, Ilias I. N. Doxiadis, J. H. Frederik Falkenburg, Frans H. J. Claas, Mirjam H. M. Heemskerk

Blood (2010) 115 (15): 3146–3157.

https://doi.org/10.1182/blood-2009-07-234906

Published: 2010

Journal Articles

Allogeneic disparities in immunoglobulin-like transcript 5 induce potent antibody responses in hematopoietic stem cell transplant recipients

Katharina Pfistershammer, Anita Lawitschka, Christoph Klauser, Judith Leitner, Roman Weigl, Mirjam H. M. Heemskerk, Winfried F. Pickl, Otto Majdic, Georg A. Böhmig, Gottfried F. Fischer, Hildegard T. Greinix, Peter Steinberger

Blood (2009) 114 (11): 2323–2332.

https://doi.org/10.1182/blood-2008-10-183814

Published: 2009

Includes: Supplemental data

Journal Articles

Defective synthesis or association of T-cell receptor chains underlies loss of surface T-cell receptor–CD3 expression in enteropathy-associated T-cell lymphoma

Jennifer M. L. Tjon, Wieke H. M. Verbeek, Yvonne M. C. Kooy-Winkelaar, Binh H. Nguyen, Arno R. van der Slik, Allan Thompson, Mirjam H. M. Heemskerk, Marco W. J. Schreurs, Liesbeth H. A. Dekking, Chris J. Mulder, Jeroen van Bergen, Frits Koning

Blood (2008) 112 (13): 5103–5110.

https://doi.org/10.1182/blood-2008-04-150748

Published: 2008

Includes: Supplemental data

Journal Articles

Multiple myeloma–reactive T cells recognize an activation-induced minor histocompatibility antigen encoded by the ATP-dependent interferon-responsive (ADIR) gene

Cornelis A. M. van Bergen, Michel G. D. Kester, Inge Jedema, Mirjam H. M. Heemskerk, Simone A. P. van Luxemburg-Heijs, Freke M. Kloosterboer, W. A. Erik Marijt, Arnoud H. de Ru, M. Ron Schaafsma, Roel Willemze, Peter A. van Veelen, J. H. Frederik Falkenburg

Blood (2007) 109 (9): 4089–4096.

https://doi.org/10.1182/blood-2006-08-043935

Published: 2007

Journal Articles

Strong selection of virus-specific cytotoxic CD4 + T-cell clones during primary human cytomegalovirus infection

Ester M. M. van Leeuwen, Ester B. M. Remmerswaal, Mirjam H. M. Heemskerk, Ineke J. M. ten Berge, Rene A. W. van Lier

Blood (2006) 108 (9): 3121–3127.

https://doi.org/10.1182/blood-2006-03-006809

Published: 2006

Journal Articles

Efficiency of T-cell receptor expression in dual-specific T cells is controlled by the intrinsic qualities of the TCR chains within the TCR-CD3 complex

Mirjam H. M. Heemskerk, Renate S. Hagedoorn, Menno A. W. G. van der Hoorn, Lars T. van der Veken, Manja Hoogeboom, Michel G. D. Kester, Roel Willemze, J. H. Frederik Falkenburg

Blood (2006) 109 (1): 235–243.

https://doi.org/10.1182/blood-2006-03-013318

Published: 2006

Journal Articles

Pretransplantation CMV-specific T cells protect recipients of T-cell-depleted grafts against CMV-related complications

Yves Chalandon, Sylvie Degermann, Jean Villard, Lionel Arlettaz, Laurent Kaiser, Solange Vischer, Steffen Walter, Mirjam H. M. Heemskerk, Rene A. W. van Lier, Claudine Helg, Bernard Chapuis, Eddy Roosnek

Blood (2006) 107 (1): 389–396.

https://doi.org/10.1182/blood-2005-07-2746

Published: 2006

Journal Articles

Redirection of antileukemic reactivity of peripheral T lymphocytes using gene transfer of minor histocompatibility antigen HA-2-specific T-cell receptor complexes expressing a conserved alpha joining region

Mirjam H. M. Heemskerk, Manja Hoogeboom, Roelof A. de Paus, Michel G. D. Kester, Menno A. W. G. van der Hoorn, Els Goulmy, Roel Willemze, J. H. Frederik Falkenburg

Blood (2003) 102 (10): 3530–3540.

https://doi.org/10.1182/blood-2003-05-1524

Published: 2003

Journal Articles

Functional role of alternatively spliced deoxycytidine kinase in sensitivity to cytarabine of acute myeloid leukemic cells

Marjan J. T. Veuger, Mirjam H. M. Heemskerk, M. Willy Honders, Roel Willemze, Renée M. Y. Barge

Blood (2002) 99 (4): 1373–1380.

https://doi.org/10.1182/blood.V99.4.1373

Published: 2002

NARROW

TCR targeting hematopoiesis to cure leukemia

TCR-based therapy for multiple myeloma and other B-cell malignancies targeting intracellular transcription factor BOB1

Therapeutic targeting of the BCR-associated protein CD79b in a TCR-based approach is hampered by aberrant expression of CD79b

TCR-transgenic lymphocytes specific for HMMR/Rhamm limit tumor outgrowth in vivo

Allo-HLA–reactive T cells inducing graft-versus-host disease are single peptide specific

Allo-HLA reactivity of virus-specific memory T cells is common

Allogeneic disparities in immunoglobulin-like transcript 5 induce potent antibody responses in hematopoietic stem cell transplant recipients

Defective synthesis or association of T-cell receptor chains underlies loss of surface T-cell receptor–CD3 expression in enteropathy-associated T-cell lymphoma

Multiple myeloma–reactive T cells recognize an activation-induced minor histocompatibility antigen encoded by the ATP-dependent interferon-responsive (ADIR) gene

Strong selection of virus-specific cytotoxic CD4 + T-cell clones during primary human cytomegalovirus infection

Efficiency of T-cell receptor expression in dual-specific T cells is controlled by the intrinsic qualities of the TCR chains within the TCR-CD3 complex

Pretransplantation CMV-specific T cells protect recipients of T-cell-depleted grafts against CMV-related complications

Redirection of antileukemic reactivity of peripheral T lymphocytes using gene transfer of minor histocompatibility antigen HA-2-specific T-cell receptor complexes expressing a conserved alpha joining region

Functional role of alternatively spliced deoxycytidine kinase in sensitivity to cytarabine of acute myeloid leukemic cells

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American Society of Hematology

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ASH Publications

American Society of Hematology

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