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Pleun Hombrink
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TCR-based therapy for multiple myeloma and other B-cell malignancies targeting intracellular transcription factor BOB1

Lorenz Jahn, Pleun Hombrink, Renate S. Hagedoorn, Michel G. D. Kester, Dirk M. van der Steen, Tania Rodriguez, Tsvetelina Pentcheva-Hoang, Arnoud H. de Ru, Marjolein P. Schoonakker, Miranda H. Meeuwsen, Marieke Griffioen, Peter A. van Veelen, J. H. Frederik Falkenburg, Mirjam H. M. Heemskerk
Journal: Blood
Blood (2017) 129 (10): 1284–1295.
https://doi.org/10.1182/blood-2016-09-737536
Published: 2017
Includes: Supplemental data
Journal Articles

T Cell Receptor Gene Therapy Targeting the Intracellular Transcription Factor Bob1 for the Treatment of Multiple Myeloma and Other B Cell Malignancies

Lorenz Jahn, Renate S. Hagedoorn, Pleun Hombrink, PhD, Michel G.D. Kester, Dirk M. van der Steen, Chopie Hassan, Marjolein P. Schoonakker, Erwin van der Pijl, Peter A. van Veelen, PhD, J.H. Frederik Falkenburg, MD PhD, Mirjam H.M. Heemskerk, PhD
Journal: Blood
Blood (2015) 126 (23): 3002.
https://doi.org/10.1182/blood.V126.23.3002.3002
Published: 2015
Journal Articles

Therapeutic targeting of the BCR-associated protein CD79b in a TCR-based approach is hampered by aberrant expression of CD79b

Lorenz Jahn, Pleun Hombrink, Chopie Hassan, Michel G. D. Kester, Dirk M. van der Steen, Renate S. Hagedoorn, J. H. Frederik Falkenburg, Peter A. van Veelen, Mirjam H. M. Heemskerk
Journal: Blood
Blood (2015) 125 (6): 949–958.
https://doi.org/10.1182/blood-2014-07-587840
Published: 2015
Includes: Supplemental data
Journal Articles

T Cell Receptors Specific for the Intracellular Transcription Factor Bob1 Allow Efficient Targeting of Human B Cell Leukemia and Multiple Myeloma

Lorenz Jahn, Pleun Hombrink, Michel G.D. Kester, Dirk M. van der Steen, Renate S. Hagedoorn, Chopie Hassan, Marjolein P. Schoonakker, Erwin van der Pijl, Peter A. van Veelen, PhD, J.H. Frederik Falkenburg, MD PhD, Mirjam H.M. Heemskerk, PhD
Journal: Blood
Blood (2014) 124 (21): 3832.
https://doi.org/10.1182/blood.V124.21.3832.3832
Published: 2014
Journal Articles

High-Affinity CD20-Specific T-Cell Receptors Suitable for Adoptive Immunotherapy in the Treatment of CD20 low B-Cell Malignancies

Lorenz Jahn, Pleun Hombrink, Chopie Hassan, Michel G.D. Kester, Renate S. Hagedoorn, Dirk M. van der Steen, Marjolein P. Schoonakker, J.H. Frederik Falkenburg, MD PhD, Peter A. van Veelen, PhD, Mirjam H.M. Heemskerk, PhD
Journal: Blood
Blood (2014) 124 (21): 3837.
https://doi.org/10.1182/blood.V124.21.3837.3837
Published: 2014
Journal Articles

HLA-Peptidomics and the Identification of Clinical Relevant Minor Histocompatibility Antigens,

Pleun Hombrink, MSc, Chopie Hassan, Michel G.D. Kester, Cornelis A.M. van Bergen, J.H.F. Falkenburg, MD, PhD, Peter A. van Veelen, Mirjam H.M. Heemskerk, PhD
Journal: Blood
Blood (2011) 118 (21): 4038.
https://doi.org/10.1182/blood.V118.21.4038.4038
Published: 2011
Journal Articles

Allogeneic HLA-A2-Restricted WT1-Specific T Cells From Mismatched Donors Are Highly Reactive but Show Potentially Hazardous Promiscuity.

Willem J.J. Falkenburg, J. Joseph Melenhorst, PhD, Michel G.D. Kester, Pleun Hombrink, Mirjam H.M. Heemskerk, PhD, Emma Gostick, David A. Price, J.H. Frederik Falkenburg, MD, PhD, A.John Barrett, MD, PhD, Inge Jedema, PhD
Journal: Blood
Blood (2009) 114 (22): 4081.
https://doi.org/10.1182/blood.V114.22.4081.4081
Published: 2009
Journal Articles

SNP-Based Genome-Wide Identification of Hematopoiesis-Restricted Minor Histocompatibility Antigens

Pleun Hombrink, MSc, Sine R Hadrup, PhD, Arne Bakker, PhD, J.H. Frederik Falkenburg, MD, PhD, Peter A. Von Dem Borne, MD, PhD, Ton N Schumacher, PhD, Mirjam H.M. Heemskerk, PhD
Journal: Blood
Blood (2008) 112 (11): 814.
https://doi.org/10.1182/blood.V112.11.814.814
Published: 2008