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Journal Articles

Cytotoxic T-Lymphocytes Recognize and Target Leukemic Stem Cells

Vanessa Schneider, Lu Zhang, Markus Rojewski, Lars Bullinger, MD PhD, Susanne Hofmann, MD, Marlies Goetz, Konstanze Doehner, MD, Hartmut Doehner, Prof., Christian Buske, MD, Jochen Greiner, MD

Blood (2014) 124 (21): 5783.

https://doi.org/10.1182/blood.V124.21.5783.5783

Published: 2014

Journal Articles

Effects Of a Novel Ceramic Biomaterial On Immune Modulatory Properties and Differentiation Potential Of Mesenchymal Stromal Cells

Blood (2013) 122 (21): 4858.

https://doi.org/10.1182/blood.V122.21.4858.4858

Published: 2013

Journal Articles

Analysis Of Leukemic Stem Cell Population Comparing NPM1 wt and NPM1 mut AML Patients and Potential Therapeutic Targets

Vanessa Schneider, Lars Bullinger, MD, PhD, Lu Zhang, Markus Rojewski, Markus Wiesneth, Susanne Hofmann, Marlies Goetz, Hubert Schrezenmeier, MD, Ulla Botzenhardt, Thomas F.E. Barth, Konstanze Doehner, MD, Hartmut Doehner, MD, Jochen Greiner, MD

Blood (2013) 122 (21): 2624.

https://doi.org/10.1182/blood.V122.21.2624.2624

Published: 2013

Journal Articles

Efficiency of Leukemic Stem Cell Separation From Patients with Acute Myeloid Leukemia

Lu Zhang, Susanne Hofmann, Lars Bullinger, Marlies Goetz, Markus Wiesneth, Markus Rojewski, Hartmut Dohner, MD, Jochen Greiner, MD, Vanessa Schneider

Blood (2011) 118 (21): 4997.

https://doi.org/10.1182/blood.V118.21.4997.4997

Published: 2011

Journal Articles

GMP-Grade Large-Scale Expansion of Bone-Marrow- (BM) Derived Human Mesenchymal Stem/Stroma Cells (MSC): Comparison of Efficacy of Different Expansion Systems and Role of Cytokines/Chemokines

Markus Rojewski, Natalie Fekete, Daniel Fuerst, Philippe Bourin, Ramin Lotfi, Volker Mailaender, Gerlinde Schmidtke-Schrezenmeier, Luc Sensebé, Hubert Schrezenmeier

Blood (2010) 116 (21): 337.

https://doi.org/10.1182/blood.V116.21.337.337

Published: 2010

Journal Articles

Co-Existing Serological Immune Responses against RHAMM Might Be a Prerequisite for Strong Cellular Immune Responses of CD8-Positive T Cells in RHAMM-R3 Peptide Vaccination for Patients with Different Hematological Malignancies.

Jochen Greiner, Susanne Hofmann, Krzysztof Giannopoulos, Markus Rojewski, Anna Babiak, Donald Bunjes, Hartmut Döhner, Anita Schmitt, Michael Schmitt

Blood (2009) 114 (22): 3671.

https://doi.org/10.1182/blood.V114.22.3671.3671

Published: 2009

Journal Articles

Peptide Vaccination Induces Dynamic Changes in CD4+ and CD8+ T Cell Subsets: Report on the First Peptide Vaccination Trial in Patients with Chronic Lymphocytic Leukemia (CLL)

Krzysztof Giannopoulos, MD, PhD, Malgorzata Kowal, Anna Dmoszynska, MD, PhD, Jacek Rolinski, Kamila Mazurek, Jochen Greiner, Markus Rojewski, Stephan Stilgenbauer, Hartmut Döhner, Michael Schmitt

Blood (2008) 112 (11): 3159.

https://doi.org/10.1182/blood.V112.11.3159.3159

Published: 2008

Journal Articles

Adoptive Transfer and Consequential Selective Reconstitution of Streptamer-Selected Cytomegalovirus-Specific CD8+ T Cells Leads to Enduring Virus Clearance in Patients after Allogeneic Stem Cell Transplantation

Anita Schmitt, Torsten Tonn, Dirk Busch, Götz Grigoleit, Hermann Einsele, Marcus Odendahl, Lothar Germeroth, Mark Ringhoffer, Simone Ringhoffer, Markus Wiesneth, Detlef Michel, Thomas Mertens, Markus Rojewski, Martin Marx, Stephanie Harsdorf, Hartmut Döhner, Erhard Seifried, Donald Bunjes, Michael Schmitt

Blood (2008) 112 (11): 1181.

https://doi.org/10.1182/blood.V112.11.1181.1181

Published: 2008

Journal Articles

High-Dose RHAMM-R3 Peptide Peptide Vaccination for Patients with Vaccination for Patients with Acute Myeloid Leukemia (AML), Myelodysplastic Syndrome (MDS), Multiple Myeloma (MM) and Chronic Lymphocytic Leukemia (CLL)

Jochen Greiner, Anita Schmitt, Krzysztof Giannopoulos, Isabel Funk, Marta Heyduk, Markus Rojewski, Jinfei Chen, Marlies Goetz, Martin Bommer, Gerd Ritter, Phillipe Guillaume, Anna Dmoszynska, Hartmut Döhner, Michael Schmitt

Blood (2008) 112 (11): 2911.

https://doi.org/10.1182/blood.V112.11.2911.2911

Published: 2008

Journal Articles

Direct Antiglobulin Test, Ferritin and GPI-Negative Cell Populations in Patients with Paroxysmal Nocturnal Hemoglobinuria (PNH) during Eculizumab Therapy: Extravascular Hemolysis Unmasked by Efficient Eculizumab-Mediated Inhibition of Intravascular Hemolysis.

Bri tta Höchsmann, Markus Rojewski, Willy A Flegel, Hubert Schrezenmeier

Blood (2008) 112 (11): 3440.

https://doi.org/10.1182/blood.V112.11.3440.3440

Published: 2008

Journal Articles

Streptamer Technology for the Assessment of CMVpp65 Specific CD8+ T Cell Frequencies and for the Adoptive T Cell Transfer to Post-Transplant Patients.

Anita Schmitt, MD, Junxia Yao, MD, Hermann Einsele, PhD, MD, Ulrich Grigoleit, MD, Dirk Busch, PhD, MD, Manuel Odendahl, MD, Lothar Germeroth, PhD, Torsten Tonn, PhD, MD, Markus Wiesneth, MD, Markus Rojewski, MD, Clemens Bechter, Stefanie von Harsdorf, MD, Hartmut Dohner, PhD, MD, Donald Bunjes, PhD, MD, Michael Schmitt, PhD, MD

Blood (2007) 110 (11): 1964.

https://doi.org/10.1182/blood.V110.11.1964.1964

Published: 2007

Journal Articles

Immunological and Clinical Responses in Patients with Acute Myeloid Leukemia (AML), Myelodysplastic Syndrome (MDS), Multiple Myeloma (MM) and Chronic Lymphocytic Leukemia (CLL) after RHAMM-R3 Peptide Vaccination.

Jochen Greiner, MD, Anita Schmitt, MD, Krzysztof Giannopoulos, MD, Jinfei Chen, MD, Marlies Goetz, Markus Rojewski, MD, Gerd Ritter, PhD, Sascha Gnjatic, PhD, Philippe Guillaume, PhD, Mark Ringhoffer, MD, Martin Bommer, MD, Richard F. Schlenk, MD, Peter Liebisch, MD, Donald Bunjes, MD, Hiroshi Shiku, PhD, Hartmut Dohner, MD, Michael Schmitt, MD

Blood (2007) 110 (11): 1806.

https://doi.org/10.1182/blood.V110.11.1806.1806

Published: 2007

Journal Articles

Tyrosine Kinase Inhibitors Dasatinib, Nilotinib and Imatinib Have an Impact on Both CD8+ T Lymphocytes and CD4+CD25+FoxP3+ Regulatory T Cells by Downregulation of the NF-κB Pathway.

Fei Fei, MD, Yingzhe Yu, Anita Schmitt, MD, Jinfei Chen, PhD, MD, Baoan Chen, PhD, MD, Markus Rojewski, MD, Mark Ringhoffer, MD, Stefanie von Harsdorf, MD, Jochen Greiner, PhD, MD, Marlies Goetz, Philippe Guillaume, PhD, Hartmut Dohner, PhD, MD, Donald Bunjes, PhD, MD, Michael Schmitt, PhD, MD

Blood (2007) 110 (11): 2368.

https://doi.org/10.1182/blood.V110.11.2368.2368

Published: 2007

Journal Articles

RHAMM/CD168-R3 Peptide Vaccination of Patients with Acute Myeloid Leukemia (AML), Myelodysplastic Syndrome (MDS) and Multiple Myeloma (MM) Elicits Immunological and Clinical Responses.

Michael Schmitt, PhD, Anita Schmitt, MD, Krzysztof Giannopoulos, MD, Li Li, PhD, Peter Liebisch, MD, Jinfei Chen, MD, Mark Ringhoffer, MD, Phillipe Guillaume, PhD, Gerd Ritter, PhD, Markus Rojewski, PhD, Sascha Gnjatic, PhD, Hartmut Dohner, MD, Jochen Jochen, MD

Blood (2006) 108 (11): 409.

https://doi.org/10.1182/blood.V108.11.409.409

Published: 2006

Journal Articles

Imatinib Inhibits Both CD4+ T Regulatory Cells and CD8+ T Lymphocytes Specifically Directed Against the Leukemia-Associated Antigen RHAMM/CD168.

Jinfei Chen, MD, Anita Schmitt, MD, Baoan Chen, MD, Markus Rojewski, MD, Jochen Greiner, MD, Philippe Guillaume, PhD, Hartmut Dohner, MD, Donald Bunjes, MD, Michael Schmitt, PhD

Blood (2006) 108 (11): 2201.

https://doi.org/10.1182/blood.V108.11.2201.2201

Published: 2006

Journal Articles

Accelerated telomere shortening in glycosylphosphatidylinositol (GPI)–negative compared with GPI-positive granulocytes from patients with paroxysmal nocturnal hemoglobinuria (PNH) detected by proaerolysin flow-FISH

Fabian Beier, Stefan Balabanov, Tom Buckley, Klaus Dietz, Ulrike Hartmann, Markus Rojewski, Lothar Kanz, Hubert Schrezenmeier, Tim H. Brümmendorf

Blood (2005) 106 (2): 531–533.

https://doi.org/10.1182/blood-2004-10-3996

Published: 2005

NARROW

Cytotoxic T-Lymphocytes Recognize and Target Leukemic Stem Cells

Effects Of a Novel Ceramic Biomaterial On Immune Modulatory Properties and Differentiation Potential Of Mesenchymal Stromal Cells

Analysis Of Leukemic Stem Cell Population Comparing NPM1 wt and NPM1 mut AML Patients and Potential Therapeutic Targets

Efficiency of Leukemic Stem Cell Separation From Patients with Acute Myeloid Leukemia

GMP-Grade Large-Scale Expansion of Bone-Marrow- (BM) Derived Human Mesenchymal Stem/Stroma Cells (MSC): Comparison of Efficacy of Different Expansion Systems and Role of Cytokines/Chemokines

Co-Existing Serological Immune Responses against RHAMM Might Be a Prerequisite for Strong Cellular Immune Responses of CD8-Positive T Cells in RHAMM-R3 Peptide Vaccination for Patients with Different Hematological Malignancies.

Peptide Vaccination Induces Dynamic Changes in CD4+ and CD8+ T Cell Subsets: Report on the First Peptide Vaccination Trial in Patients with Chronic Lymphocytic Leukemia (CLL)

Adoptive Transfer and Consequential Selective Reconstitution of Streptamer-Selected Cytomegalovirus-Specific CD8+ T Cells Leads to Enduring Virus Clearance in Patients after Allogeneic Stem Cell Transplantation

High-Dose RHAMM-R3 Peptide Peptide Vaccination for Patients with Vaccination for Patients with Acute Myeloid Leukemia (AML), Myelodysplastic Syndrome (MDS), Multiple Myeloma (MM) and Chronic Lymphocytic Leukemia (CLL)

Direct Antiglobulin Test, Ferritin and GPI-Negative Cell Populations in Patients with Paroxysmal Nocturnal Hemoglobinuria (PNH) during Eculizumab Therapy: Extravascular Hemolysis Unmasked by Efficient Eculizumab-Mediated Inhibition of Intravascular Hemolysis.

Streptamer Technology for the Assessment of CMVpp65 Specific CD8+ T Cell Frequencies and for the Adoptive T Cell Transfer to Post-Transplant Patients.

Immunological and Clinical Responses in Patients with Acute Myeloid Leukemia (AML), Myelodysplastic Syndrome (MDS), Multiple Myeloma (MM) and Chronic Lymphocytic Leukemia (CLL) after RHAMM-R3 Peptide Vaccination.

Tyrosine Kinase Inhibitors Dasatinib, Nilotinib and Imatinib Have an Impact on Both CD8+ T Lymphocytes and CD4+CD25+FoxP3+ Regulatory T Cells by Downregulation of the NF-κB Pathway.

RHAMM/CD168-R3 Peptide Vaccination of Patients with Acute Myeloid Leukemia (AML), Myelodysplastic Syndrome (MDS) and Multiple Myeloma (MM) Elicits Immunological and Clinical Responses.

Imatinib Inhibits Both CD4+ T Regulatory Cells and CD8+ T Lymphocytes Specifically Directed Against the Leukemia-Associated Antigen RHAMM/CD168.

Accelerated telomere shortening in glycosylphosphatidylinositol (GPI)–negative compared with GPI-positive granulocytes from patients with paroxysmal nocturnal hemoglobinuria (PNH) detected by proaerolysin flow-FISH

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American Society of Hematology

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American Society of Hematology

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