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Journal Articles

Acquired Hemophilia and Plasma Cell Neoplasms, a Rare Association

Katarzyna Aleksandra Jalowiec, Martin Andres, Behrouz Mansouri Taleghani, Anne Angelillo-Scherrer, MD PhD, Alicia Rovo, Johanna A. Kremer Hovinga, MD Prof

Blood (2019) 134 (Supplement_1): 4930.

https://doi.org/10.1182/blood-2019-128048

Published: 2019

Journal Articles

Data Coming out of the Human Inhibitor PUP Study (HIPS) Reveal 4 Subgroups of Patients with Distinct Antibody Signatures

Blood (2018) 132 (Supplement 1): 3774.

https://doi.org/10.1182/blood-2018-99-115979

Published: 2018

Journal Articles

A Novel Mechanism of Factor VIIa/Tissue Factor (TF)-Catalyzed Activation and Inactivation of B-Domain-Deleted Factor VIII in the Early Initiation Phases of Coagulation

Yuto Nakajima, MD, Koji Yada, MD PhD, Keiji Nogami, MDPhD, Midori Shima, MD PhD

Blood (2018) 132 (Supplement 1): 1162.

https://doi.org/10.1182/blood-2018-99-115645

Published: 2018

Journal Articles

A Neutralizing Monoclonal Antibody (PF-06741086) Against Tissue Factor Pathway Inhibitor in Combination with Activated Prothrombin Complex Concentrate Increases Hemostasis in Inhibitor Hemophilia Plasmas without Excessive Thrombin Generation

Swapnil Rakhe, MS, Sheryl Bowley, PhD, John E. Murphy, PhD, Debra D Pittman, MS

Blood (2018) 132 (Supplement 1): 3779.

https://doi.org/10.1182/blood-2018-99-119831

Published: 2018

Journal Articles

Characteristics of Males with Hemophilia in the United States Hemophilia Treatment Center Network (USHTCN) with New-Onset Elevated Inhibitor Titers, December 15, 2013 - December 31, 2016

Marilyn J Manco-Johnson, MD, J. Michael Soucie, PhD, Anjali Sharathkumar, MBBS, MDMS, Fiona Bethea, MPH, Christine L Kempton, Amanda B. Payne, MPH, Michael Wang, MD, Connie H Miller, PhD

Blood (2017) 130 (Supplement 1): 3408.

https://doi.org/10.1182/blood.V130.Suppl_1.3408.3408

Published: 2017

Journal Articles

Centralized Laboratory Testing for Inhibitors in the U.S. Hemophilia Treatment Centers Network: Testing Protocol and Results on 10,178 Specimens

Connie H Miller, PhD, Dorothy Ellingsen, Jennifer Driggers, Brian Boylan, Amanda B. Payne, MPH, Fiona Bethea, MPH, Vanessa R Byams, MPH, J. Michael Soucie, PhD, Christopher J. Bean, PhD

Blood (2017) 130 (Supplement 1): 3692.

https://doi.org/10.1182/blood.V130.Suppl_1.3692.3692

Published: 2017

Journal Articles

The Impact of Anti-Factor VIII A1 and A3 Domain Antibodies in the Immune Reponse to Factor VIII in Patients with Hemophilia a

Jasmine C Ito, Courtney Cox, MSc, W. Hunter Baldwin, BS, Christopher B Doering, PhD, Shannon L. Meeks, MD

Blood (2017) 130 (Supplement 1): 2373.

https://doi.org/10.1182/blood.V130.Suppl_1.2373.2373

Published: 2017

Journal Articles

Longitudinal Antibody Signatures Following FVIII Replacement Therapy in Previously Untreated Patients with Severe Hemophilia Α- New Insights from the Hemophilia Inhibitor PUP Study (HIPS)

Bagirath Gangadharan, PhD, Birgit Reipert, Fritz Scheiflinger, PhD, Joel Bowen, Elizabeth Donnachie, PhD, Karin Fijn van Draat, Ralph A. Gruppo, MD, Jenny Klintman, MD PhD, Christoph Male, MD, Catherine E. McGuinn, MD, Shannon L. Meeks, MD, Michael Recht, MD PhD, Margaret V. Ragni, MD MPH, Hassan M. Yaish, MD, Amy D. Shapiro, MD, Donald L Yee, MD, Vlad Calin Radulescu, MD, Elena Santagostino, Deborah Brown, MD

Blood (2017) 130 (Supplement 1): 88.

https://doi.org/10.1182/blood.V130.Suppl_1.88.88

Published: 2017

Journal Articles

Frequency and epitope specificity of anti–factor VIII C1 domain antibodies in acquired and congenital hemophilia A

Joerg Kahle, Aleksander Orlowski, Diana Stichel, John F. Healey, Ernest T. Parker, Marc Jacquemin, Manuela Krause, Andreas Tiede, Dirk Schwabe, Pete Lollar, Christoph Königs

Blood (2017) 130 (6): 808–816.

https://doi.org/10.1182/blood-2016-11-751347

Published: 2017

Includes: Supplemental data

Journal Articles

Appearance of High-Affinity Antibodies Precedes Clinical Diagnosis of FVIII Inhibitors - Preliminary Analysis from the Hemophilia Inhibitor PUP Study (HIPS)

Birgit M Reipert, PhD, Bagirath Gangadharan, PhD, Christoph J Hofbauer, PhD, Fritz Scheiflinger, PhD, Joel Bowen, Elizabeth Donnachie, PhD, Karen Fijvandraat, MD, Ralph A. Gruppo, MD, Jenny Klintman, MD PhD, Christoph Male, MD, Catherine E. McGuinn, MD, Shannon L. Meeks, MD, Michael Recht, MD PhD, M V Ragni, MD, Hassan M Yaish, Elena Santagostino, MD PhD, Deborah L Brown, MD

Blood (2016) 128 (22): 328.

https://doi.org/10.1182/blood.V128.22.328.328

Published: 2016

Journal Articles

Platelet-Targeted rFVIIa-Xten Improves Thrombin Generation and Fibrin Formation Compared to Recombinant FVIIa

Maria M. Aleman, PhD, Elena N. Kistanova, Nancy Moore, Volker Schellenberger, PhD, Robert Peters, PhD, Joe Salas, PhD

Blood (2015) 126 (23): 2269.

https://doi.org/10.1182/blood.V126.23.2269.2269

Published: 2015

Journal Articles

Regulatory T Cell Response to Factor VIII in Mothers of Children with Hemophilia Inhibitors

Margaret V. Ragni, MD MPH, Lynn M. Malec, MD, Craig D. Seaman, MD, Lisa Butterfield, PhD

Blood (2015) 126 (23): 3512.

https://doi.org/10.1182/blood.V126.23.3512.3512

Published: 2015

Journal Articles

Frequency and Epitope Specificity of Anti-Factor VIII C1 Domain Antibodies in Acquired and Hereditary Hemophilia Inhibitor Patient Plasma

Joerg Kahle, PhD, Aleksander Orlowski, Anja Schmidt, PhD, Kerstin Brettschneider, Thomas Klingebiel, MD, John F Healey, BS, Ernest T Parker, BA, John (Pete) S Lollar, MD, Marc Jacquemin, MD, Manuela Krause, MD, Andreas Tiede, MD PhD, Dirk Schwabe, MD, Christoph Königs, MD PhD

Blood (2015) 126 (23): 3491.

https://doi.org/10.1182/blood.V126.23.3491.3491

Published: 2015

Journal Articles

Thrombin Generation and Bleeding in Hemophilia Inhibitor Patients during Immune Tolerance Induction

Margaret V. Ragni, MD MPH, Donna DiMichele, MD, Charles R.M. Hay, MD FRCP, FRCPath, Lynn M. Malec, MD, Craig D. Seaman, MD, Jonathan Yabes, PhD, Jie Li, MS, Saulius Butenas, PhD, Kathleen Brumel-Ziedins, PhD

Blood (2014) 124 (21): 1514.

https://doi.org/10.1182/blood.V124.21.1514.1514

Published: 2014

Journal Articles

Generation and Functional Properties Of FVIII-Specific Human T Regulatory Cells: A Novel Approach Using Hemophilia A patient’s T Cell Receptors

Yongchan Kim, PhD, Yan Su, PhD, Robert J. Rossi, B.A., Ruth A. Ettinger, Ph.D., Kathleen P. Pratt, Ph.D., David William Scott, PhD, Ethan Shevach, MD

Blood (2013) 122 (21): 3568.

https://doi.org/10.1182/blood.V122.21.3568.3568

Published: 2013

Journal Articles

The polygenic nature of inhibitors in hemophilia A: results from the Hemophilia Inhibitor Genetics Study (HIGS) Combined Cohort

Jan Astermark, Sharyne M. Donfield, Edward D. Gomperts, John Schwarz, Erika D. Menius, Anna Pavlova, Johannes Oldenburg, Bailey Kessing, Donna M. DiMichele, Amy D. Shapiro, Cheryl A. Winkler, Erik Berntorp

Blood (2013) 121 (8): 1446–1454.

https://doi.org/10.1182/blood-2012-06-434803

Published: 2013

Includes: Supplemental data

Journal Articles

Immune Tolerance Induction (ITI) in Adults with Congenital Hemophilia: A Multicenter Experience

Rebecca Kruse-Jarres, MD/MPH, Maria Elisa Mancuso, MD, PhD, Eva Mingot Castellano, MD, Johnny Mahlangu, MD

Blood (2012) 120 (21): 1123.

https://doi.org/10.1182/blood.V120.21.1123.1123

Published: 2012

Journal Articles

Continued Transmission of Parvovirus B19 in Plasma-Derived Factor Concentrates After the Implementation of B19 Nucleic Acid Plasma Minipool Screening,

J. Michael Soucie, Ph.D., Christine De Staercke, PhD, Meera B. Chitlur, MD, Ralph A. Gruppo, MD, W Craig Hooper, PhD, Craig M. Kessler, MD, Roshni Kulkarni, MD, Marilyn J. Manco-Johnson, MD, Paul E. Monahan, MD, Meredith Oakley, MPH, Jerry Powell, MD, Meredith Pyle, MS, Michael Recht, MD, PhD, Brenda Riske, MS, MBA, MPA, Hernan Sabio, MD, Sean Trimble, MPH

Blood (2011) 118 (21): 3378.

https://doi.org/10.1182/blood.V118.21.3378.3378

Published: 2011

Journal Articles

A novel mechanism of Enhancing the Haemostatic Effect in the Combination with Recombinant Factor VIII and Activated Prothrombin Complex Concentrate(APCC) in Hemophilia A Patients with Inhibitor

Koji Yada, MD, Keiji Nogami, MD, PhD, Kenichi Ogiwara, MD, PhD, Midori Shima, MD, PhD

Blood (2011) 118 (21): 1178.

https://doi.org/10.1182/blood.V118.21.1178.1178

Published: 2011

Journal Articles

Genetic Factors Associated with Inhibitor Development in Hemophilia A: Initial Results From the Hemophilia Inhibitor Genetics Study (HIGS) Combined Cohort.

Jan Astermark, MD, PhD, John Schwarz, MA, Sharyne M. Donfield, PhD, Donna M. DiMichele, MD, Bruce M. Ewenstein, MD, PhD, Edward D. Gomperts, MD, George W. Nelson, PhD, Johannes Oldenburg, MD, PhD, Amy D. Shapiro, MD, Gerald Spotts, PhD, Cheryl A. Winkler, PhD, Erik Berntorp, MD, PhD

Blood (2009) 114 (22): 217.

https://doi.org/10.1182/blood.V114.22.217.217

Published: 2009

NARROW

Acquired Hemophilia and Plasma Cell Neoplasms, a Rare Association

Data Coming out of the Human Inhibitor PUP Study (HIPS) Reveal 4 Subgroups of Patients with Distinct Antibody Signatures

A Novel Mechanism of Factor VIIa/Tissue Factor (TF)-Catalyzed Activation and Inactivation of B-Domain-Deleted Factor VIII in the Early Initiation Phases of Coagulation

A Neutralizing Monoclonal Antibody (PF-06741086) Against Tissue Factor Pathway Inhibitor in Combination with Activated Prothrombin Complex Concentrate Increases Hemostasis in Inhibitor Hemophilia Plasmas without Excessive Thrombin Generation

Characteristics of Males with Hemophilia in the United States Hemophilia Treatment Center Network (USHTCN) with New-Onset Elevated Inhibitor Titers, December 15, 2013 - December 31, 2016

Centralized Laboratory Testing for Inhibitors in the U.S. Hemophilia Treatment Centers Network: Testing Protocol and Results on 10,178 Specimens

The Impact of Anti-Factor VIII A1 and A3 Domain Antibodies in the Immune Reponse to Factor VIII in Patients with Hemophilia a

Longitudinal Antibody Signatures Following FVIII Replacement Therapy in Previously Untreated Patients with Severe Hemophilia Α- New Insights from the Hemophilia Inhibitor PUP Study (HIPS)

Frequency and epitope specificity of anti–factor VIII C1 domain antibodies in acquired and congenital hemophilia A

Appearance of High-Affinity Antibodies Precedes Clinical Diagnosis of FVIII Inhibitors - Preliminary Analysis from the Hemophilia Inhibitor PUP Study (HIPS)

Platelet-Targeted rFVIIa-Xten Improves Thrombin Generation and Fibrin Formation Compared to Recombinant FVIIa

Regulatory T Cell Response to Factor VIII in Mothers of Children with Hemophilia Inhibitors

Frequency and Epitope Specificity of Anti-Factor VIII C1 Domain Antibodies in Acquired and Hereditary Hemophilia Inhibitor Patient Plasma

Thrombin Generation and Bleeding in Hemophilia Inhibitor Patients during Immune Tolerance Induction

Generation and Functional Properties Of FVIII-Specific Human T Regulatory Cells: A Novel Approach Using Hemophilia A patient’s T Cell Receptors

The polygenic nature of inhibitors in hemophilia A: results from the Hemophilia Inhibitor Genetics Study (HIGS) Combined Cohort

Immune Tolerance Induction (ITI) in Adults with Congenital Hemophilia: A Multicenter Experience

Continued Transmission of Parvovirus B19 in Plasma-Derived Factor Concentrates After the Implementation of B19 Nucleic Acid Plasma Minipool Screening,

A novel mechanism of Enhancing the Haemostatic Effect in the Combination with Recombinant Factor VIII and Activated Prothrombin Complex Concentrate(APCC) in Hemophilia A Patients with Inhibitor

Genetic Factors Associated with Inhibitor Development in Hemophilia A: Initial Results From the Hemophilia Inhibitor Genetics Study (HIGS) Combined Cohort.

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American Society of Hematology

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ASH Publications

American Society of Hematology

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