Page 1 | Search Results | Blood | American Society of Hematology

1-20 of 95

Sort by

Sort Order Select

Journal Articles

Disruption of the Akt-FoxO Axis As a Safeguard Mechanism for the Hematopoietic Stem Cell Compartment during Chronic Metabolic Stress

Vinothini Govindarajah, PhD, Jung-Mi Lee, PhD, Michael Solomon, Bryan Goddard, Ramesh C. Nayak, PhD, Jose A Cancelas, MD, Damien Reynaud

Blood (2019) 134 (Supplement_1): 1201.

https://doi.org/10.1182/blood-2019-127222

Published: 2019

Journal Articles

Role of HDAC8 Upregulation in Resistance of FLT3-ITD AML Stem Cells to FLT3 Inhibitors

Jun Long, Mingyuan Jia, Weiyue Fang, Xinjie Chen, Zhongyu Wang, Lili Mu, Rufang Xiang, Jun-Min LI, MD PhD, Dengli Hong, PhD, Aibin Liang, MD PhD, Jiong Hu, MD

Blood (2019) 134 (Supplement_1): 1268.

https://doi.org/10.1182/blood-2019-128394

Published: 2019

Journal Articles

Akt Inhibition Differently Controls PRC2 Components and Synergizes with Dual EZH2/1 Inhibitor in the Treatment of Multiple Myeloma

Mohamed Rizk, BSc, MSc, Ola Rizq, MD PhD, Motohiko Oshima, PhD, Yaeko Nakajima-Takagi, PhD, Shuhei Koide, PhD, Atsunori Saraya, Yusuke Isshiki, MD PhD, Tetsuhiro Chiba, MD PhD, Satoshi Yamazaki, PhD, Anqi Ma, PhD, Jian Jin, PhD, Atsushi Iwama, MD PhD, Naoya Mimura, MD PhD

Blood (2019) 134 (Supplement_1): 4400.

https://doi.org/10.1182/blood-2019-122157

Published: 2019

Journal Articles

Chromoplexy and Chromothripsis Are Important Prognostically in Myeloma and Deregulate Gene Function By a Range of Mechanisms

Cody Ashby, PhD, Eileen M Boyle, MD MSc, Brian A Walker, PhD, Michael A Bauer, PhD, Katie Rose Ryan, PhD, Judith Dent, Anjan Thakurta, Erin Flynt, Faith E. Davies, MD, Gareth Morgan, MD PhD

Blood (2019) 134 (Supplement_1): 3767.

https://doi.org/10.1182/blood-2019-130335

Published: 2019

Journal Articles

Association between GLUT1 and HbF Levels in Red Blood Cells from Patients with Sickle Cell Disease

Alireza Paikari, MD, Ankush Goyal, MA, Christelle Cousin, PhD, Vincent Petit, DVM, PhD, Vivien A. Sheehan, MD PhD

Blood (2019) 134 (Supplement_1): 2265.

https://doi.org/10.1182/blood-2019-131058

Published: 2019

Journal Articles

Prognostic Significance of FOXO3 in Pediatric Acute Myeloid Leukemia (AML) Patients Treated with Bortezomib Addition to Standard Therapy: Results from a Children's Oncology Group Phase 3 Clinical Trial

Anneke D. van Dijk, BS, Peter P. Ruvolo, PhD, Fieke W Hoff, BSc, Yihua Qiu, Alan S Gamis, MD MPH, Richard Aplenc, MD PhD, Anders E. Kolb, MD, Todd A. Alonzo, PhD, Robert B. Gerbing, Eveline S. de Bont, MD PhD, Sophia W.M. Bruggeman, PhD, Terzah M Horton, MD PhD, Steven M. Kornblau, MD

Blood (2019) 134 (Supplement_1): 2676.

https://doi.org/10.1182/blood-2019-128579

Published: 2019

Journal Articles

Comprehensive Analysis of MYC Translocations in Multiple Myeloma By Whole Genome Sequencing and Whole Transcriptome Sequencing

Sonja Seliger, Verena Geirhos, Torsten Haferlach, MD, Wolfgang Kern, MD, Wencke Walter, PhD, Manja Meggendorfer, PhD, Constance Baer, PhD, Anna Stengel, PhD, Claudia Haferlach, MD

Blood (2019) 134 (Supplement_1): 1774.

https://doi.org/10.1182/blood-2019-124704

Published: 2019

Journal Articles

Regulation of Fetal Hemoglobin through the Insulin Signaling Pathway

Alireza Paikari, MD, Yankai Zhang, PhD, Alicia Chang, MD, Ankush Goyal, MA, Evadnie Rampersaud, PhD, Jonathan M. Flanagan, PhD, Mitchell J. Weiss, MD, PhD, Vivien A. Sheehan, MD PhD

Blood (2019) 134 (Supplement_1): 811.

https://doi.org/10.1182/blood-2019-131313

Published: 2019

Journal Articles

Role of Signal Transducing Adaptor Protein-1 (STAP-1) in Chronic Myelogenous Leukemia Stem Cells

Jun Toda, MD, Michiko Ichii, MD PhD, Hirohiko Shibayama, MD PhD, Hideaki Saito, MD, Yuichi Kitai, Ryuta Muromoto, Jun-ichi Kashiwakura, Kodai Saitoh, Tadashi Matsuda, Kenji Oritani, MD PhD, Yuzuru Kanakura, MD PhD

Blood (2018) 132 (Supplement 1): 4245.

https://doi.org/10.1182/blood-2018-99-113725

Published: 2018

Journal Articles

Interferon-alfa2 Treatment of Patients with Polycythemia Vera and Related Neoplasms Impacts Deregulation of Oxidative Stress Genes and Antioxidative Defence Mechanisms. Potential Implications of IFN-Alfa Induced Changes in TP53, NRF2 and CXCR4 for Genomic Instability and CD34+ Mobilisation

Vibe Skov, PhD, Caroline Riley, PhD, Mads Thomassen, PhD, Lasse Kjær, PhD, Thomas Stauffer Larsen, MD PhD, Ole Weis Bjerrum, MD PhD, Torben A Kruse, Hans Carl Hasselbalch, Professor, dr.MD

Blood (2018) 132 (Supplement 1): 4326.

https://doi.org/10.1182/blood-2018-99-112109

Published: 2018

Journal Articles

The Role of Adenosine Monophosphate Activated Protein Kinase Alpha 1 (AMPK) in Gamma-Globin Regulation

Alicia Chang, MD, Yankai Zhang, PhD, Nelda Itzep, MD, Vivien A Sheehan, MD PhD

Blood (2018) 132 (Supplement 1): 413.

https://doi.org/10.1182/blood-2018-99-117092

Published: 2018

Journal Articles

Insulin-like Growth Factor Binding Protein-3 (IGFBP3) Induces Fetal Hemoglobin in Hematopoietic Stem and Progenitor Cells from Patients with Sickle Cell Anemia

Alireza Paikari, MD, Tian Mi, PhD, Yankai Zhang, PhD, Evadnie Rampersaud, PhD, Guolian Kang, PhD, Gang Wu, PhD, Jane S. Hankins, MD MS, Jeremie H. Estepp, MD, Pavel Sumazin, PhD, Mitchell J. Weiss, MD PhD, Vivien A Sheehan, MD PhD

Blood (2018) 132 (Supplement 1): 722.

https://doi.org/10.1182/blood-2018-99-115383

Published: 2018

Journal Articles

Functional Analysis of the FOXO3 Gene on the Induction of Fetal Hemoglobin in K562 Cells

Flávia Peixoto Albuquerque, MD, Pedro Luis Franca-Neto, MSc, Rafael de Oliveira Franca, PhD, Aderson da Silva Araujo, PhD, Fernando F. Costa, MD, PhD, Marcos Bezerra, BSc, MSc, PhD, Antonio R. Lucena-Araujo, PhD

Blood (2018) 132 (Supplement 1): 2390.

https://doi.org/10.1182/blood-2018-99-111994

Published: 2018

Journal Articles

Single-Cell Analysis Reveals Sequential Genetic Events from Hematopoietic Stem Cell Differentiation Hierarchy in Multiple Myeloma Patients with FGFR3/IGH Translocation

Wen Zhou, PhD, Fenghuang Zhan, MD PhD

Blood (2018) 132 (Supplement 1): 5598.

https://doi.org/10.1182/blood-2018-99-115606

Published: 2018

Journal Articles

Proliferation and Molecular Risk Score of Low Risk Myeloma Cells Are Increased in High Risk Microenvironment Via Augmented Bioavailability of Growth Factors

Syed J. Mehdi, PhD, Sarah K Johnson, PhD, Sharmin Khan, Wen Ling, PhD, Randal Shelton, Joshua Epstein, DSc, Frits van Rhee, MD PhD, Maurizio Zangari, MD, Carolina D. Schinke, MD, Sharmilan Thanendrarajan, MD, Brian A Walker, PhD, Cody Ashby, PhD, Faith E. Davies, MD, Gareth Morgan, MD, Shmuel Yaccoby, PhD

Blood (2018) 132 (Supplement 1): 1929.

https://doi.org/10.1182/blood-2018-99-116455

Published: 2018

Journal Articles

Metformin induces FOXO3-dependent fetal hemoglobin production in human primary erythroid cells

Yankai Zhang, Alireza Paikari, Pavel Sumazin, Carly C. Ginter Summarell, Jacy R. Crosby, Eric Boerwinkle, Mitchell J. Weiss, Vivien A. Sheehan

Blood (2018) 132 (3): 321–333.

https://doi.org/10.1182/blood-2017-11-814335

Published: 2018

Includes: Supplemental data

Journal Articles

Improved Clinical Outcomes in Adults with Sickle Cell Disease and Diabetes Treated with Metformin

Sherif M. Badawy, MD, Amanda B. Payne, MPH, Sundar S. Shrestha, PhD, Scott D. Grosse, PhD

Blood (2017) 130 (Supplement 1): 3534.

https://doi.org/10.1182/blood.V130.Suppl_1.3534.3534

Published: 2017

Journal Articles

XPO1 Inhibition Targets Transcriptional Vulnerability of FLT3-ITD+D835 Double Mutant AML through p53 Accumulation and Inhibition of Oncogenic Transcription Factors: Lesson Learned from Cage Sequencing of Primary AML Cells

Kotoko Yamatani, MD PhD, Yoko Tabe, MD PhD, Kazumasa Sekihara, PhD, Haeun Yang, Kaori Saito, Weiguo Zhang, MD PhD, Kazuho Ikeo, PhD, Sonoko Kinjo, Kaoru Mogushi, PhD, Masaki Hosoya, Yoshihide Hayashizaki, MD PhD, Yasunari Yamanaka, MD PhD, Hironori Harada, Takashi Miida, MD PhD, Marina Konopleva, MD PhD, Michael Andreeff, MD PhD

Blood (2017) 130 (Supplement 1): 1244.

https://doi.org/10.1182/blood.V130.Suppl_1.1244.1244

Published: 2017

Journal Articles

Piceatannol Induces Fetal Hemoglobin in Erythroid Progenitor Cells from Patients with Sickle Cell Disease

Yankai Zhang, PhD, Alicia Chang, MD, Pavel Sumazin, PhD, Vivien Sheehan, MD PhD

Blood (2017) 130 (Supplement 1): 2221.

https://doi.org/10.1182/blood.V130.Suppl_1.2221.2221

Published: 2017

Journal Articles

Metformin Induction of Fetal Hemoglobin

Yankai Zhang, PhD, Alireza Paikari, MD, Pavel Sumazin, PhD, Alex George, MD, PhD, Bogdan Dinu, MD, Carly Summarell, MS, Mitchell J Weiss, MD PhD, Vivien Sheehan, MD PhD

Blood (2017) 130 (Supplement 1): 359.

https://doi.org/10.1182/blood.V130.Suppl_1.359.359

Published: 2017

NARROW

Disruption of the Akt-FoxO Axis As a Safeguard Mechanism for the Hematopoietic Stem Cell Compartment during Chronic Metabolic Stress

Role of HDAC8 Upregulation in Resistance of FLT3-ITD AML Stem Cells to FLT3 Inhibitors

Akt Inhibition Differently Controls PRC2 Components and Synergizes with Dual EZH2/1 Inhibitor in the Treatment of Multiple Myeloma

Chromoplexy and Chromothripsis Are Important Prognostically in Myeloma and Deregulate Gene Function By a Range of Mechanisms

Association between GLUT1 and HbF Levels in Red Blood Cells from Patients with Sickle Cell Disease

Prognostic Significance of FOXO3 in Pediatric Acute Myeloid Leukemia (AML) Patients Treated with Bortezomib Addition to Standard Therapy: Results from a Children's Oncology Group Phase 3 Clinical Trial

Comprehensive Analysis of MYC Translocations in Multiple Myeloma By Whole Genome Sequencing and Whole Transcriptome Sequencing

Regulation of Fetal Hemoglobin through the Insulin Signaling Pathway

Role of Signal Transducing Adaptor Protein-1 (STAP-1) in Chronic Myelogenous Leukemia Stem Cells

Interferon-alfa2 Treatment of Patients with Polycythemia Vera and Related Neoplasms Impacts Deregulation of Oxidative Stress Genes and Antioxidative Defence Mechanisms. Potential Implications of IFN-Alfa Induced Changes in TP53, NRF2 and CXCR4 for Genomic Instability and CD34+ Mobilisation

The Role of Adenosine Monophosphate Activated Protein Kinase Alpha 1 (AMPK) in Gamma-Globin Regulation

Insulin-like Growth Factor Binding Protein-3 (IGFBP3) Induces Fetal Hemoglobin in Hematopoietic Stem and Progenitor Cells from Patients with Sickle Cell Anemia

Functional Analysis of the FOXO3 Gene on the Induction of Fetal Hemoglobin in K562 Cells

Single-Cell Analysis Reveals Sequential Genetic Events from Hematopoietic Stem Cell Differentiation Hierarchy in Multiple Myeloma Patients with FGFR3/IGH Translocation

Proliferation and Molecular Risk Score of Low Risk Myeloma Cells Are Increased in High Risk Microenvironment Via Augmented Bioavailability of Growth Factors

Metformin induces FOXO3-dependent fetal hemoglobin production in human primary erythroid cells

Improved Clinical Outcomes in Adults with Sickle Cell Disease and Diabetes Treated with Metformin

XPO1 Inhibition Targets Transcriptional Vulnerability of FLT3-ITD+D835 Double Mutant AML through p53 Accumulation and Inhibition of Oncogenic Transcription Factors: Lesson Learned from Cage Sequencing of Primary AML Cells

Piceatannol Induces Fetal Hemoglobin in Erythroid Progenitor Cells from Patients with Sickle Cell Disease

Metformin Induction of Fetal Hemoglobin

Email alerts

ASH Publications

American Society of Hematology

Email alerts

ASH Publications

American Society of Hematology

This Feature Is Available To Subscribers Only