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Journal Articles

FoxO1-GAB1 axis regulates homing capacity and tonic AKT activity in chronic lymphocytic leukemia

Vaclav Seda, Eva Vojackova, Laura Ondrisova, Lenka Kostalova, Sonali Sharma, Tomas Loja, Gabriela Mladonicka Pavlasova, Daniel Zicha, Marie Kudlickova Peskova, Jan Krivanek, Kvetoslava Liskova, Leos Kren, Vladimir Benes, Katerina Musilova Litzmanova, Marek Borsky, Jan Oppelt, Jan Verner, Sarka Pospisilova, Yvona Brychtova, Anna Panovska, Zhi Tan, Shuxing Zhang, Michael Doubek, Katerina Amruz Cerna, Jiri Mayer, Marek Mraz
Journal: Blood
Blood (2021) 138 (9): 758–772.
https://doi.org/10.1182/blood.2020008101
Published: 2021
Includes: Supplemental data
Journal Articles

Recurrent Patterns of Clonal Evolution in Relapsed-Refractory DLBCL Following Treatment with R-CHOP

Christopher Rushton, BSc, Sarah E Arthur, BSc, Miguel Alcaide, PhD, Matthew Cheung, BSc, Nicole Thomas, BSc, Laura K Hilton, PhD, Neil R Michaud, Scott Daigle, Jordan Davidson, BSc, Kevin R Bushell, BSc, MSc, Stephen Yu, MSc, Michael D. Jain, MD PhD, Lois E. Shepherd, Michael Crump, MD FRCPC, Koren Kathleen Mann, PhD, John Kuruvilla, MD, Sarit Assouline, MD, Kirstie Cleary, PhD, Mark S Cragg, Prof, David W. Scott, MBChB, PhD, Nathalie Johnson, MD, Ryan D. Morin, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 921.
https://doi.org/10.1182/blood-2019-127399
Published: 2019
Journal Articles

Integrative Immunogenomic Characterization of Diffuse Large B-Cell Lymphoma (DLBCL) Identifies Four Molecular Subtypes with Distinct Immune Landscapes

Michael Leukam, MDMS, James Godfrey, MD, Sravya Tumuluru, Girish Venkataraman, MD MBBS, Sonali M. Smith, MD, Riyue Bao, PhD, Justin Kline, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 924.
https://doi.org/10.1182/blood-2019-131562
Published: 2019
Journal Articles

Genome-Wide Histone Acetylation Profiling in Chronic Lymphocytic Leukemia Reveals a Distinctive Signature in Stereotyped Subset #8

Maria Tsagiopoulou, Vicente Chapaprieta, Nuria Russiñol, Fotis Psomopoulos, Nikos Papakonstantinou, Niki Stavroyianni, Achilles Anagnostopoulos, Panagoula Kollia, PhD, Elias Campo, Kostas Stamatopoulos, José I. Martin-Subero
Journal: Blood
Blood (2019) 134 (Supplement_1): 1241.
https://doi.org/10.1182/blood-2019-127817
Published: 2019
Journal Articles

Coagulation FXIII-a Protein Expression Defines Three Novel Sub-Populations in Pediatric B-Cell Progenitor Acute Lymphoblastic Leukemia Characterized By Distinct Gene Expression Signatures

Katalin Gyurina, MSc, BSc, Bettina Kárai, MD PhD, Anikó Ujfalusi, MD PhD, Zsuzsanna Hevessy, MD PhD, Gábor Barna, PhD, Pál Jáksó, MD PhD, Gyönygi Pálfi-Mészáros, Szilárd Páliska, PhD, Beáta Scholtz, PhD, János Kappelmayer, MD PhD DSc, Gábor Zahuczky, PhD, Csongor Kiss, MD PhD DSc
Journal: Blood
Blood (2019) 134 (Supplement_1): 2523.
https://doi.org/10.1182/blood-2019-124333
Published: 2019
Journal Articles

Evaluation of the m7-FLIPI in Patients with Follicular Lymphoma Treated within the Gallium Trial: EZH2 mutation Status May be a Predictive Marker for Differential Efficacy of Chemotherapy

Vindi Jurinovic, PhD, Verena Passerini, PhD, Mikkel Z Oestergaard, PhD, Andrea Knapp, PhD, Kirsten Mundt, PhD, Shamzah Araf, MRCP, MBBS, PhD, Julia Richter, PhD, Jude Fitzgibbon, PhD, Wolfram Klapper, Robert E. Marcus, FRCP, Andrew Davies, MD PhD, Michael Herold, MD, Wolfgang Hiddemann, PhD, Michael Unterhalt, PhD, Eva Hoster, PhD, Oliver Weigert, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 122.
https://doi.org/10.1182/blood-2019-130208
Published: 2019
Journal Articles

Identification of an Immune Risk Score to Predict the Prognosis of Acute Myeloid Leukemia

Yang Liang, PhD, Yun Wang, Yan-Yu Cai, Siliang Chen, Run-Cong Nie, Zhe-Yuan Qin, PhD, Fang Hu, Weida Wang, MD, Yu-Jun Dai, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 708.
https://doi.org/10.1182/blood-2019-126733
Published: 2019
Journal Articles

PRMT5 Inhibition Drives Therapeutic Vulnerability to BCL-2 Inhibition with Venetoclax and Provides Rationale for Combination Therapy in Mantle Cell Lymphoma

Fiona Brown, BS, Yang Zhang, PhD, Claire Hinterschied, Alexander Prouty, BS, Shelby Sloan, BS, JoBeth Helmig-Mason, Msc, Ji Hyun Chung, PhD, Kris Vaddi, PhD, Selina Chen-Kiang, PhD, Maurizio Di Liberto, PhD, Lapo Alinari, MD PhD, Peggy Scherle, PhD, Rosa Lapalombella, PhD, Jihye Paik, PhD, Robert A Baiocchi, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 302.
https://doi.org/10.1182/blood-2019-130797
Published: 2019
Journal Articles

Protein Phosphatase 2A Activation Dependent Down Regulation of PGC1-Alpha and FOXO1 Phosphorylation with OSU-2S in Human Lymphoma Cells

Sohaila Mohamed Khalil, Swagata Goswami, MSc, Xiaokui Mo, PhD MAS, Natarajan Muthusamy, DVM,PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 3977.
https://doi.org/10.1182/blood-2019-129224
Published: 2019
Journal Articles

Role of HDAC8 Upregulation in Resistance of FLT3-ITD AML Stem Cells to FLT3 Inhibitors

Jun Long, Mingyuan Jia, Weiyue Fang, Xinjie Chen, Zhongyu Wang, Lili Mu, Rufang Xiang, Jun-Min LI, MD PhD, Dengli Hong, PhD, Aibin Liang, MD PhD, Jiong Hu, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 1268.
https://doi.org/10.1182/blood-2019-128394
Published: 2019
Journal Articles

Towards Understanding & Uncovering New Key Players in T-Cell Development upon Aging

Hanane Boukarabila, PhD, Kalpana Nattamai, Medhanie Assmelash Mulaw, PhD, Hartmut Geiger, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 2482.
https://doi.org/10.1182/blood-2019-127294
Published: 2019
Journal Articles

Molecular Characterisation of Diffuse Large B Cell Lymphoma in Patients of 80 Years Old or More: Clinical Relevance in a Multicentric Randomized Phase III Study of the Lysa (SENIOR Study)

Elodie Bohers, PhD, Pierre-Julien Viailly, Philippe Ruminy, PhD, Vinciane Marchand, Mathieu Viennot, Victor Bobée, PharmD, Vincent Delwail, Frederic Peyrade, MD, Herve Maisonneuve, MD, Julie Abraham, MD, Catherine Thieblemont, MD PhD, Pierre Feugier, MD PhD, Gilles A. Salles, MD PhD, Fontanet Bijou, MD, Gandhi Damaj, MD PhD, Gian-Matteo Pica, MD, Peggy Dartigues-Cuillères, MD, Philippe Gaulard, MD PhD, Jean-François Emile, MD PhD, Bettina Fabiani, Herve Tilly, MD PhD, Corinne Haioun, MD PhD, Steven Le Gouill, Rene-Olivier Casasnovas, MD, Fabrice Jardin
Journal: Blood
Blood (2019) 134 (Supplement_1): 2765.
https://doi.org/10.1182/blood-2019-124444
Published: 2019
Journal Articles

Interaction of Mantle Cell Lymphoma with the Microenvironment Induces Phospho Akt-Mediated Resistance Against BTK Inhibition and Can be Overcome By Co-Treatment with a Specific Akt Inhibitor (MK-2206)

Elisabeth Silkenstedt, MD, Claudia Schwandner, Johanna Deuss, Natalie Mack, Yvonne Zimmermann, Martin Dreyling, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 2802.
https://doi.org/10.1182/blood-2019-128782
Published: 2019
Journal Articles

Somatic Mutation Profile Analyzed By Next-Generation Sequencing in Relapsed/Refractory Follicular Lymphoma Treated with Idelalisib

Philippine Robert, Cédric Rossi, MD PhD, Romain Aucagne, PhD, Caroline Chapusot, Selim Ramla, MD, Robin Noel, MD, Reda Bouabdallah, Morgan Avenin, MD, Luc Xerri, MD PhD, Elise Toussaint, MD, Marie-Pierre Chenard, MD PhD, Luc Mathieu Fornecker, MD PhD, Adrien Chauchet, MD, Isabelle Bedgedjian, MD, Anne Quinquenel, MD, Saviz Nasri, Aude Marchal, MD PhD, Alain Jacques Delmer, MD PhD, Juliette Bouteloup, MD, Jean-Noel Bastie, MD PhD, Laurent Martin, MD PhD, Mary Callanan, PhD, Olivier Casasnovas, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 1503.
https://doi.org/10.1182/blood-2019-126459
Published: 2019
Journal Articles

Nuclear FOXO1 promotes lymphomagenesis in germinal center B cells

Eleni Kabrani, Van Trung Chu, Evangelia Tasouri, Thomas Sommermann, Kevin Baßler, Thomas Ulas, Thorsten Zenz, Lars Bullinger, Joachim L. Schultze, Klaus Rajewsky, Sandrine Sander
Journal: Blood
Blood (2018) 132 (25): 2670–2683.
https://doi.org/10.1182/blood-2018-06-856203
Published: 2018
Includes: Supplemental data
Journal Articles

Nuclear Fox(O1): not so fantastic

Marc A. Weniger
Journal: Blood
Blood (2018) 132 (25): 2616–2618.
https://doi.org/10.1182/blood-2018-11-882175
Published: 2018
Journal Articles

Prognostic Biomarkers Converge on a Germinal Centre Dark Zone Phenotype As a Determinant of Adverse Outcome in Follicular Lymphoma Patients Treated with Rituximab and Chemotherapy

Anjali Silva, PhD MSc, BSc, Clementine Sarkozy, MD, Tracy Lackraj, PhD BSc, Anja Mottok, Vindi Jurinovic, MSc, Laurie H Sehn, MD MPH, Oliver Weigert, MD, Christian Steidl, MD, Robert Kridel, PhD MD
Journal: Blood
Blood (2018) 132 (Supplement 1): 4095.
https://doi.org/10.1182/blood-2018-99-112689
Published: 2018
Journal Articles

Updated Report on Identification of Molecular Predictors of Tazemetostat Response in an Ongoing NHL Phase 2 Study

Alice McDonald, Elizabeth Thomas, Scott Daigle, Franck Morschhauser, Gilles Salles, MD PhD, Vincent Ribrag, Pamela McKay, MD, Herve Tilly, MD, Anna Schmitt, Connie Lee Batlevi, MD, Christophe Fruchart, Peter Johnson, MD, Michael Dickinson, MD, Stephen Opat, Wojciech Jurczak, Guillaume Cartron, Thierry Lamy, Pier Luigi Zinzani, MD, Sarit Assouline, John Radford, MD FRCP, John G. Gribben, Corinne Haioun, MD, Aristeidis Chaidos, MD PhD, Steven Le Gouill, MD PhD, Alicia Clawson, John Larus, Stephen J Blakemore
Journal: Blood
Blood (2018) 132 (Supplement 1): 4097.
https://doi.org/10.1182/blood-2018-99-115132
Published: 2018
Journal Articles

Whole Exome Analysis Reveals Key Genomic Differences between Sporadic and Endemic Pediatric Burkitt Lymphoma

Denice Mae Palmos, BS, Rikhia Chakraborty, PhD, Harshal Abhyankar, MS, Joy C. Jayaseelan, MS, Maria F. Cardenas, BS, Joyce Kambugu, MBChB, Jeff Otiti, MBChB, Fadhil Geriga, MBChB, Pietro Pala, MD, John Sekabira, MBChB, MMed, Peter Wasswa, MBChB, Joseph Ssenyondwa, MBChB, Jackson Orem, MBChB, MMed, PhD, David A. Wheeler, PhD, Joseph Lubega, MBChB, MPH, Carl E. Allen, MD PhD, Donald Williams Parsons, MD PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 4117.
https://doi.org/10.1182/blood-2018-99-110762
Published: 2018
Journal Articles

Functional Analysis of the FOXO3 Gene on the Induction of Fetal Hemoglobin in K562 Cells

Flávia Peixoto Albuquerque, MD, Pedro Luis Franca-Neto, MSc, Rafael de Oliveira Franca, PhD, Aderson da Silva Araujo, PhD, Fernando F. Costa, MD, PhD, Marcos Bezerra, BSc, MSc, PhD, Antonio R. Lucena-Araujo, PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 2390.
https://doi.org/10.1182/blood-2018-99-111994
Published: 2018