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Journal Articles

Targeting of canonical WNT signaling ameliorates experimental sclerodermatous chronic graft-versus-host disease

Blood (2021) 137 (17): 2403–2416.

https://doi.org/10.1182/blood.2020008720

Published: 2021

Includes: Supplemental data

Journal Articles

Analysis of disease model iPSCs derived from patients with a novel Fanconi anemia–like IBMFS ADH5/ALDH2 deficiency

Anfeng Mu, Asuka Hira, Akira Niwa, Mitsujiro Osawa, Kenichi Yoshida, Minako Mori, Yusuke Okamoto, Kazuko Inoue, Keita Kondo, Masato T. Kanemaki, Tomonari Matsuda, Etsuro Ito, Seiji Kojima, Tatsutoshi Nakahata, Seishi Ogawa, Keigo Tanaka, Keitaro Matsuo, Megumu K. Saito, Minoru Takata

Blood (2021) 137 (15): 2021–2032.

https://doi.org/10.1182/blood.2020009111

Published: 2021

Includes: Supplemental data

Journal Articles

Defective palmitoylation of transferrin receptor triggers iron overload in Friedreich ataxia fibroblasts

Floriane Petit, Anthony Drecourt, Michaël Dussiot, Coralie Zangarelli, Olivier Hermine, Arnold Munnich, Agnès Rötig

Blood (2021) 137 (15): 2090–2102.

https://doi.org/10.1182/blood.2020006987

Published: 2021

Includes: Multimedia, Supplemental data

Journal Articles

Neutrophil extracellular traps promote fibrous vascular occlusions in chronic thrombosis

Smriti Sharma, Thomas M. Hofbauer, Anna S. Ondracek, Stella Chausheva, Arman Alimohammadi, Tyler Artner, Adelheid Panzenboeck, Johanna Rinderer, Inbal Shafran, Andreas Mangold, Robert Winker, Evelyne Wohlschläger-Krenn, Bernhard Moser, Shahrokh Taghavi, Walter Klepetko, Klaus T. Preissner, Irene M. Lang

Blood (2021) 137 (8): 1104–1116.

https://doi.org/10.1182/blood.2020005861

Published: 2021

Includes: Supplemental data

Journal Articles

MKL1 deficiency results in a severe neutrophil motility defect due to impaired actin polymerization

Blood (2020) 135 (24): 2171–2181.

https://doi.org/10.1182/blood.2019002633

Published: 2020

Includes: Multimedia, Supplemental data

Journal Articles

The Splenic Microenvironment Is a Novel Site of Relapse Following ABT-199 Treatment

Alessandra Di Grande, BSc, Sofie Piers, Pieter Van Vlierberghe, PhD, Triona Ni Chonghaile, PhD BSc

Blood (2019) 134 (Supplement_1): 3800.

https://doi.org/10.1182/blood-2019-127970

Published: 2019

Journal Articles

Heme Oxygenase-1 in Leukemia Cells Promotes Cancer Associated Fibroblasts Mediating Progression of Acute Lymphoblastic Leukemia

Chengyun Pan, Dan Ma, MD, Qin Fang, Ping Liu, Jishi Wang, PhD

Blood (2019) 134 (Supplement_1): 3958.

https://doi.org/10.1182/blood-2019-130440

Published: 2019

Journal Articles

An Autosomal Dominant SCID Form Due to a Gain of Function Mutation in the RAC2 Gene

Chantal Lagresle-Peyrou, PhD, Aurélien Olichon, Hanem Sadek, Philippe Roche, Claudine Tardy, Cindy Da Silva, Alexandrine Garrigue, Alain Fischer, MD PhD, Despina Moshous, MD PhD, Yves Collette, Capucine Picard, MD PhD, Jean-Laurent Casanova, PhD MD, Isabelle André, PhD, Marina Cavazzana, MD PhD

Blood (2019) 134 (Supplement_1): 3742.

https://doi.org/10.1182/blood-2019-126855

Published: 2019

Journal Articles

Tumor Suppressor Function of Dnmt3b in Hematologic Malignancies Critically Depends on Its Catalytic Activity

Katarina Lopusna, PhD, Pawel Nowialis, PhD, Staci L. Haney, PhD, Ajay Abraham, PhD, Jana Opavska, Rene Opavsky, PhD

Blood (2019) 134 (Supplement_1): 3788.

https://doi.org/10.1182/blood-2019-130857

Published: 2019

Journal Articles

New Germline Syndrome Discovery: Heterozygous CSF3R Mutations May Predispose to Myeloid and Lymphoid Malignancies

Amy M Trottier, MDBSc,MSc, Ira L Kraft, MD, Lawrence J Druhan, PhD, Amanda Lance, MS, Belinda R Avalos, MD, Lucy A Godley, MD PhD

Blood (2019) 134 (Supplement_1): 2543.

https://doi.org/10.1182/blood-2019-129492

Published: 2019

Journal Articles

Mutant ASXL1 Disrupts Paraspeckle Formation through Aberrant Interaction with Nono in Hematopoietic Cells

Yamamoto Keita, MD, Susumu Goyama, MD PhD, Shuhei Asada, MD PhD, Takeshi Fujino, MD, Tomofusa Fukuyama, MD PhD, Yosuke Tanaka, MD, Ayana Kon, MD PhD, Yasuhito Nannya, MD PhD, Seishi Ogawa, MD PhD, Reina Onoguchi, PhD, Nobuyoshi Akimitsu, PhD, Toshio Kitamura, MD PhD

Blood (2019) 134 (Supplement_1): 2514.

https://doi.org/10.1182/blood-2019-125472

Published: 2019

Journal Articles

Modeling Transient Myeloproliferative Disorder Using Induced Pluripotent Stem Cells and CRISPR/Cas9 Technology

Sonali Barwe, PhD MSc, E. Anders Kolb, MD, Anilkumar Gopalakrishnapillai, PhD

Blood (2019) 134 (Supplement_1): 2738.

https://doi.org/10.1182/blood-2019-130934

Published: 2019

Journal Articles

Targeting NEK2 Induces Cellular Senescence in B-Cell Malignancies through p53-Independent Signaling Pathways

Yuqi Zhu, Ye Yang, PhD, Yogesh Jethava, MBBS,MDFRCPath,MRCP, Ivana Frech, DSc, PhD MBA, Guido J. Tricot, MD PhD, Fenghuang Zhan, MD PhD

Blood (2019) 134 (Supplement_1): 3102.

https://doi.org/10.1182/blood-2019-123815

Published: 2019

Journal Articles

Complementary Base Editing Approaches for the Treatment of Sickle Cell Disease and Beta Thalassemia

Ling Lin, PhD, Adrian P. Rybak, PhD, Conrad Rinaldi, M.S., Jonathan Yen, PhD, Yanfang Fu, PhD, Elsie Akrawi, Sarah Smith, Scott J. Haskett, M.S., Minerva E. Sanchez, Yeh-Chuin Poh, PhD, Michael S. Packer, PhD, Nicole M. Gaudelli, PhD, Manmohan Singh, PhD, Giuseppe Ciaramella, PhD, B.Sc., Dana N. Levasseur, PhD

Blood (2019) 134 (Supplement_1): 3352.

https://doi.org/10.1182/blood-2019-126710

Published: 2019

Journal Articles

Targeting AML: The Development of Two Functionally and Mechanistically Distinct Classes of Cereblon-Mediated Protein Homeostatic Modulators

Aparajita Hoskote Chourasia, PhD, Leah Fung, PhD, Brooke McElwee, BSc, Normand Richard, MSc, Imelda Lam, BSc, Eduardo Torres, MSc, Paul Erdman, MSc, Robert Sullivan, PhD, David Hecht, PhD, Kyle WH Chan, PhD, Frank Mercurio, PhD, David I Stirling, PhD

Blood (2019) 134 (Supplement_1): 3361.

https://doi.org/10.1182/blood-2019-131872

Published: 2019

Journal Articles

Induction of a Leukemic Bone Marrow Niche Mediated By TGFB1 of Leukemic Blasts in Pediatric Acute Mekaryoblastic Leukemia: Results of an in Vitro and In Vivo Analysis

Theresa Hack, MSc, Stefanie Bertram, MD, Guntram Büsche, MD, Helmut Hanenberg, MD, Ludger Klein-Hitpass, PhD, Nils Von Neuhoff, PhD, Dirk Reinhardt, MD, Markus Schneider, PhD, Mareike Rasche, MD

Blood (2019) 134 (Supplement_1): 3734.

https://doi.org/10.1182/blood-2019-126536

Published: 2019

Journal Articles

Vδ1+ T Cells: Adoptive Cell Therapy for the Treatment of Haematological Malignancies in Allogeneic Settings

André Simoes, PhD, Joanna Kawalkowska, PhD, Timothy Recaldin, PhD, Daniel Foxler, PhD, Oliver Nussbaumer, PhD, Michael Koslowski, MD

Blood (2019) 134 (Supplement_1): 3221.

https://doi.org/10.1182/blood-2019-125688

Published: 2019

Journal Articles

SIX1 Is a Novel Effector Gene in CALM-AF10 Leukemia

Waitman K. Aumann, MDMS, Catherine P. Lavau, DVM, PhD, Amanda Harrington, MD, Amanda E. Conway, PhD, Daniel S. Wechsler, MD PhD

Blood (2019) 134 (Supplement_1): 5035.

https://doi.org/10.1182/blood-2019-130178

Published: 2019

Journal Articles

Targeting Cancer Associated Fibroblasts in the Bone Marrow Prevents Resistance to Chimeric Antigen Receptor T Cell Therapy in Multiple Myeloma

Reona Sakemura, MD PhD, Michelle J. Cox, Michael J. Hansen, Mehrdad Hefazi, MD, Claudia Manriquez Roman, Kendall J. Schick, Erin E. Tapper, Paulina Roman Moreno, MD, Michael W. Ruff, MD, Denise K Walters, PhD BSc, Sameer A. Parikh, MD, Neil E. Kay, MD, Saad S. Kenderian, MD

Blood (2019) 134 (Supplement_1): 865.

https://doi.org/10.1182/blood-2019-123277

Published: 2019

Journal Articles

Ibrutinib and Venetoclax Target Distinct Subpopulation of CLL Cells: Rationale for Drug Combination and Implication of Minimal Residual Disease Eradication

Y. Lynn Lynn Wang, MD PhD, Carrie Franzen, PhD, Shengchun Wang, MD PhD, Girish Venkataraman, MD MBBS, Lei Li, MS, Nifang Niu, PhD, Madina Sukhanova, PhD, Yifan Tu, MD PhD, Juehua Gao, MD PhD, Yi-Hua Chen, MD, Shuo Ma, MD PhD, Richard A. Larson, MD, Lu Pin, MD PhD

Blood (2019) 134 (Supplement_1): 475.

https://doi.org/10.1182/blood-2019-125396

Published: 2019

NARROW

Targeting of canonical WNT signaling ameliorates experimental sclerodermatous chronic graft-versus-host disease

Analysis of disease model iPSCs derived from patients with a novel Fanconi anemia–like IBMFS ADH5/ALDH2 deficiency

Defective palmitoylation of transferrin receptor triggers iron overload in Friedreich ataxia fibroblasts

Neutrophil extracellular traps promote fibrous vascular occlusions in chronic thrombosis

MKL1 deficiency results in a severe neutrophil motility defect due to impaired actin polymerization

The Splenic Microenvironment Is a Novel Site of Relapse Following ABT-199 Treatment

Heme Oxygenase-1 in Leukemia Cells Promotes Cancer Associated Fibroblasts Mediating Progression of Acute Lymphoblastic Leukemia

An Autosomal Dominant SCID Form Due to a Gain of Function Mutation in the RAC2 Gene

Tumor Suppressor Function of Dnmt3b in Hematologic Malignancies Critically Depends on Its Catalytic Activity

New Germline Syndrome Discovery: Heterozygous CSF3R Mutations May Predispose to Myeloid and Lymphoid Malignancies

Mutant ASXL1 Disrupts Paraspeckle Formation through Aberrant Interaction with Nono in Hematopoietic Cells

Modeling Transient Myeloproliferative Disorder Using Induced Pluripotent Stem Cells and CRISPR/Cas9 Technology

Targeting NEK2 Induces Cellular Senescence in B-Cell Malignancies through p53-Independent Signaling Pathways

Complementary Base Editing Approaches for the Treatment of Sickle Cell Disease and Beta Thalassemia

Targeting AML: The Development of Two Functionally and Mechanistically Distinct Classes of Cereblon-Mediated Protein Homeostatic Modulators

Induction of a Leukemic Bone Marrow Niche Mediated By TGFB1 of Leukemic Blasts in Pediatric Acute Mekaryoblastic Leukemia: Results of an in Vitro and In Vivo Analysis

Vδ1+ T Cells: Adoptive Cell Therapy for the Treatment of Haematological Malignancies in Allogeneic Settings

SIX1 Is a Novel Effector Gene in CALM-AF10 Leukemia

Targeting Cancer Associated Fibroblasts in the Bone Marrow Prevents Resistance to Chimeric Antigen Receptor T Cell Therapy in Multiple Myeloma

Ibrutinib and Venetoclax Target Distinct Subpopulation of CLL Cells: Rationale for Drug Combination and Implication of Minimal Residual Disease Eradication

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American Society of Hematology

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ASH Publications

American Society of Hematology

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