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Journal Articles

CRISPR Screens Identify Mechanisms of Natural Killer Cell Evasion across Blood Cancers

Olli Dufva, Khalid Saeed, Sara Gandolfi, MD, Michal Sheffer, PhD, Jay Klievink, Petri Pölönen, MSc, Tiina Hannunen, Mette Ilander, PhD, Pekka Ellonen, BSc, Matti Kankainen, PhD, Dean Anthony Lee, MD PhD, Constantine S. Mitsiades, MD PhD, Satu Mustjoki, MD PhD

Blood (2019) 134 (Supplement_1): 3597.

https://doi.org/10.1182/blood-2019-129837

Published: 2019

Journal Articles

Dimethyl Oxalyl Glycine a Prolyl Hydroxylase Inhibitor Decreases Early Gastrointestinal Gvhd Via Two Independent Pathways of Apoptosis after Allogeneic Hematopoietic Cell Transplantation

Reena Kumari, PhD, Senthilnathan Palaniyandi, PhD, Ethan Strattan, BS, Sabarinath Venniyil Radhakrishnan, MBBS, MD, Gerhard Carl Hildebrandt, MD

Blood (2018) 132 (Supplement 1): 3317.

https://doi.org/10.1182/blood-2018-99-116245

Published: 2018

Journal Articles

Phase II Trial of Ixazomib and Dexamethasone Versus Ixazomib, Dexamethasone and Lenalidomide, Randomized with NFKB2 Rearrangement. (Proteasome Inhibitor NFKB2 Rearrangement Driven Trial, PINR)

Leon Bernal-Mizrachi, MD, Craig E. Cole, MD, Leonard Heffner, MD, Ajay K Nooka, MDMPH, Ravi Vij, MBBS, Nyaya Kelkar, Akshata Sridhar, Munevver Cinar, MD, Zhengjia Chen, PhD, Zhao Chang, PhD, Sagar Lonial, MD, Jonathan L Kaufman, MD

Blood (2018) 132 (Supplement 1): 2011.

https://doi.org/10.1182/blood-2018-99-119337

Published: 2018

Journal Articles

CAR T Cell Cytotoxicity Is Dependent on Death Receptor-Driven Apoptosis

Nathan Singh, MD, Olga Shestova, PhD, Katharina Hayer, Albert Hong, Pranali Ravikumar, MS, Atushi Hoshino, MD PhD, Ophir Shalem, PhD, Matthew D. Weitzman, PhD, Carl H June, MD, Saar I. Gill, MDPhD, Marco Ruella, MD

Blood (2018) 132 (Supplement 1): 698.

https://doi.org/10.1182/blood-2018-99-117328

Published: 2018

Journal Articles

A Novel PU.1 - Caspase 8/cFLIP Axis in Neutrophil and Macrophage Differentiation of AML Cells

Magali Humbert, PhD, Mario P. Tschan, PhD, Aladin Haimovici, Bruce E. Torbett, PhD, Nicolas Niklaus, MSc, BSc

Blood (2018) 132 (Supplement 1): 1347.

https://doi.org/10.1182/blood-2018-99-112797

Published: 2018

Journal Articles

Comprehensive Sequencing Analysis in Subcutaneous Panniculitis-like T-Cell Lymphoma

Blood (2017) 130 (Supplement 1): 3999.

https://doi.org/10.1182/blood.V130.Suppl_1.3999.3999

Published: 2017

Journal Articles

The Long Form of Cellular FLIP Renders NK-Cell Lymphoma Cells Resistant to Fas-Mediated Apoptosis

Yasushi Isobe, MD, PhD, Azuchi Masuda, MD, Koichi Sugimoto, MD, PhD, Norio Komatsu, MD PhD

Blood (2016) 128 (22): 4129.

https://doi.org/10.1182/blood.V128.22.4129.4129

Published: 2016

Journal Articles

The RNA-Binding Protein Musashi 2 Is Upregulated in the Proliferative Fraction of CLL Clones, Particularly in U-CLL Patients, and Its Silencing Induces Programmed Cell Death

Florencia Palacios, PhD, Xiao J. Yan, MD PhD, Jacqueline C. Barrientos, MD, Jonathan E. Kolitz, MD, Steven L. Allen, MD, Kanti R. Rai, MD, Nicholas Chiorazzi, MD

Blood (2016) 128 (22): 3216.

https://doi.org/10.1182/blood.V128.22.3216.3216

Published: 2016

Journal Articles

Cflar Splicing SNP As Predictor of Chemo-Sensitivity to Anticancer Drugs

Lata Chauhan, PhD, Emilie J Bergsma, Jatinder K Lamba, PhD

Blood (2015) 126 (23): 2056.

https://doi.org/10.1182/blood.V126.23.2056.2056

Published: 2015

Journal Articles

PTK7 Is Involved in the Chemotherapy Resistance of T-Cell Acute Lymphoblastic Leukemia through Interaction with FADD-Death Domain

Hideki Goto, MD PhD, Rachel Wilkie Grantham, PhD, Motoaki Mizuuchi, Tetsuji Yamaguchi, Takanori Teshima, MD PhD, John C. Reed, MD PhD, Shu-ichi Matsuzawa, PhD

Blood (2015) 126 (23): 3701.

https://doi.org/10.1182/blood.V126.23.3701.3701

Published: 2015

Journal Articles

Proapoptotic Bid Preserves HSC Function through Restraint of Necroptosis

Patrice N. Wagner, B.S., Qiong Shi, B.S., Yuri D. Fedoriw, MD, Sandra S. Zinkel, MD PhD

Blood (2014) 124 (21): 251.

https://doi.org/10.1182/blood.V124.21.251.251

Published: 2014

Journal Articles

Assessing the Mechanism of Cytarabine-Induced Killing in Acute Leukemia

Nicole Dionne Vincelette, Seongseok Yun, MD, PhD

Blood (2014) 124 (21): 5210.

https://doi.org/10.1182/blood.V124.21.5210.5210

Published: 2014

Journal Articles

SIRPB1 Is a Strong Predictor Biomarker of Response to 5-Azacitidine Therapy in MDS and AML Patients

Blood (2014) 124 (21): 1030.

https://doi.org/10.1182/blood.V124.21.1030.1030

Published: 2014

Journal Articles

Smac mimetic and glucocorticoids synergize to induce apoptosis in childhood ALL by promoting ripoptosome assembly

Katharina Belz, Hannah Schoeneberger, Sibylle Wehner, Andreas Weigert, Halvard Bönig, Thomas Klingebiel, Iduna Fichtner, Simone Fulda

Blood (2014) 124 (2): 240–250.

https://doi.org/10.1182/blood-2013-05-500918

Published: 2014

Includes: Supplemental data

Journal Articles

CD7 Expression On Blasts Of Myelodysplastic Syndromes Is Associated With Apoptosis Resistance With Decreased Expression Of The Proapoptotic Protein Bad and An Independent Unfavorable Prognostic Factor Together With The Revised IPSS Score In Patients

Yasuko Hamada, MD, Hideto Tamura, MD, PhD, Mariko Ishibashi, PhD, Namiko Okuyama, MD, Asaka Kondo, MD, PhD, Keiichi Moriya, MD, PhD, Kiyoyuki Ogata, MD, PhD, Keiji Kakumoto, Yoshihide Miyazaki, Akira Matsuda, MD, PhD, Kaoru Tohyama, MD, PhD, Yasunori Ueda, MD, PhD, Mineo Kurokawa, MD, PhD, Hirohiko Shibayama, Nobuhiko Emi, MD, PhD, Kinuko Mitani, M.D., Ph.D., Tomoki Naoe, MD, PhD, Haruo Sugiyama, MD, PhD, Koiti Inokuchi, MD, PhD

Blood (2013) 122 (21): 2799.

https://doi.org/10.1182/blood.V122.21.2799.2799

Published: 2013

Journal Articles

Necroptotic Death Of RIPK1-Deficient HSC Compromises Hematopoiesis

Ben A Croker, O'Donnell A Joanne, Donald Metcalf, Rickard James, Joseph Evans, Seth L. Masters, Andrew W. Roberts, MBBS, PhD, Motti Gerlic, John Silke

Blood (2013) 122 (21): 218.

https://doi.org/10.1182/blood.V122.21.218.218

Published: 2013

Journal Articles

Mechanism of Regulating Fas Signaling by Promyelocytic Leukemia Protein (PML) and Its Dominant-Negative Mutant PMLRARα

Rong-Hua Tao, M.D., Ph.D., Zuzana Berkova, PhD, Jillian F Wise, B.S., Haifeng Zhu, Ph.D., Xue Ao, MS, Zeming Chen, PhD, Wenzhuo Zhuang, PhD, Frank K Braun, PhD, Rohit Mathur, PhD, Felipe Samaniego, M.D.

Blood (2012) 120 (21): 1327.

https://doi.org/10.1182/blood.V120.21.1327.1327

Published: 2012

Journal Articles

Platelet Production Occurs Independently of Both the Intrinsic and Extrinsic Apoptosis Pathways

Emma C. Josefsson, Deborah L. Burnett, Marlyse A. Debrincat, Katya J. Henley, Rachael M. Lane, Marion Lebois, Lorraine A. O'Reilly, Marc Pellegrini, Simon P. Preston, Ben A. Croker, Donald Metcalf, Andreas Strasser, Benjamin T. Kile

Blood (2012) 120 (21): 389.

https://doi.org/10.1182/blood.V120.21.389.389

Published: 2012

Journal Articles

Fingolimod (FTY720) Overcomes the Resistance to Tyrosine Kinase Inhibitors Via Dual Activation of BIM and BID in Chronic Myelogenous Leukemia

Miki Kiyota, MD, Junya Kuroda, MD, PhD, Mio Yamamoto-Sugitani, MD, PhD, Yuji Shimura, MD, Ryuko Nakayama, MD, Hisao Nagoshi, MD, Shinsuke Mizutani, MD, Yoshiaki Chinen, MD, Natsumi Sakamoto, Tsutomu Kobayashi, MD, PhD, Yosuke Matsumoto, MD, PhD, Shigeo Horiike, MD, PhD, Tomohiko Taki, MD, PhD, Masafumi Taniwaki, MD, PhD

Blood (2012) 120 (21): 3744.

https://doi.org/10.1182/blood.V120.21.3744.3744

Published: 2012

Journal Articles

Impact of Lenalidomide on Gene Expression Profiles of Malignant and Immune Cells in Patients with Chronic Lymphocytic Leukemia

John C. Riches, MD, Ajanthah Sangaralingam, PhD, Shahryar Kiaii, BSc, MSc, PhD, Tracy Chaplin, BSc, Demet Cekdemir, MD, Sameena Iqbal, Alan G. Ramsay, PhD, John G. Gribben, MD, DSc

Blood (2011) 118 (21): 976.

https://doi.org/10.1182/blood.V118.21.976.976

Published: 2011

NARROW

CRISPR Screens Identify Mechanisms of Natural Killer Cell Evasion across Blood Cancers

Dimethyl Oxalyl Glycine a Prolyl Hydroxylase Inhibitor Decreases Early Gastrointestinal Gvhd Via Two Independent Pathways of Apoptosis after Allogeneic Hematopoietic Cell Transplantation

Phase II Trial of Ixazomib and Dexamethasone Versus Ixazomib, Dexamethasone and Lenalidomide, Randomized with NFKB2 Rearrangement. (Proteasome Inhibitor NFKB2 Rearrangement Driven Trial, PINR)

CAR T Cell Cytotoxicity Is Dependent on Death Receptor-Driven Apoptosis

A Novel PU.1 - Caspase 8/cFLIP Axis in Neutrophil and Macrophage Differentiation of AML Cells

Comprehensive Sequencing Analysis in Subcutaneous Panniculitis-like T-Cell Lymphoma

The Long Form of Cellular FLIP Renders NK-Cell Lymphoma Cells Resistant to Fas-Mediated Apoptosis

The RNA-Binding Protein Musashi 2 Is Upregulated in the Proliferative Fraction of CLL Clones, Particularly in U-CLL Patients, and Its Silencing Induces Programmed Cell Death

Cflar Splicing SNP As Predictor of Chemo-Sensitivity to Anticancer Drugs

PTK7 Is Involved in the Chemotherapy Resistance of T-Cell Acute Lymphoblastic Leukemia through Interaction with FADD-Death Domain

Proapoptotic Bid Preserves HSC Function through Restraint of Necroptosis

Assessing the Mechanism of Cytarabine-Induced Killing in Acute Leukemia

SIRPB1 Is a Strong Predictor Biomarker of Response to 5-Azacitidine Therapy in MDS and AML Patients

Smac mimetic and glucocorticoids synergize to induce apoptosis in childhood ALL by promoting ripoptosome assembly

CD7 Expression On Blasts Of Myelodysplastic Syndromes Is Associated With Apoptosis Resistance With Decreased Expression Of The Proapoptotic Protein Bad and An Independent Unfavorable Prognostic Factor Together With The Revised IPSS Score In Patients

Necroptotic Death Of RIPK1-Deficient HSC Compromises Hematopoiesis

Mechanism of Regulating Fas Signaling by Promyelocytic Leukemia Protein (PML) and Its Dominant-Negative Mutant PMLRARα

Platelet Production Occurs Independently of Both the Intrinsic and Extrinsic Apoptosis Pathways

Fingolimod (FTY720) Overcomes the Resistance to Tyrosine Kinase Inhibitors Via Dual Activation of BIM and BID in Chronic Myelogenous Leukemia

Impact of Lenalidomide on Gene Expression Profiles of Malignant and Immune Cells in Patients with Chronic Lymphocytic Leukemia

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American Society of Hematology

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American Society of Hematology

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